Registration Dossier

Data platform availability banner - registered substances factsheets

Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Ecotoxicological information

Toxicity to birds

Currently viewing:

Administrative data

Link to relevant study record(s)

Description of key information

No study on toxicity to birds is available.

Key value for chemical safety assessment

Additional information

No studies on the long-term reproductive toxicity to birds are available for the substance.
In Annex X, Section 9.6.1, Column 2 of Regulation (EC) No 1907/2006, it is laid down that any need for testing should be carefully considered taking into account the large mammalian dataset that is usually available at this tonnage level. In case of the substance a mammalian dataset is available. Furthermore, ECHA (2017) states in the "Guidance on information requirements and chemical safety assessment Chapter R.7c" (R.7.10.16) that "given that mammalian toxicity is considered in detail for human health protection, the need for additional data for birds must be considered very carefully – new tests are a last resort in the data collection process."
In case of 1,2-dimethylimidazole (CAS 1739-84-0) a mammalian dataset is available.
In addition, based on the low log Kow, significant bioaccumulation in organisms is not to be expected (see IUCLID Ch. 5.3.1). The Substance is also biodegradable based on an enhanced ready biodegradability test passing the test level of 60% CO2/ThCO2 but not meeting the 10-day window (BASF SE, 2012; see IUCLID Ch 5.2.1); therefore, the substance is assessed to be not P/vP. Hence, secondary poisoning is of no concern.
Therefore, and for reasons of animal welfare, long-term or reproductive toxicity tests on birds do not need to be conducted.