Registration Dossier
Registration Dossier
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The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
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EC number: 201-755-0 | CAS number: 87-59-2
Acute Toxicity: other routes
Administrative data
- Endpoint:
- acute toxicity: other routes
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: Secondary Literature, no details of study available. Secondary literature reliable.
Data source
Referenceopen allclose all
- Reference Type:
- secondary source
- Title:
- Xylidine, BUA Stoffbericht 161
- Year:
- 1 994
- Bibliographic source:
- BUA, Beratergremium für umweltrelevante Altstoffe (BUA) der Gesellschaft Deutscher Chemiker, S.Hirzel Verlag 1995
- Reference Type:
- secondary source
- Title:
- Database value
- Year:
- 2 011
- Bibliographic source:
- ACToR Database
Materials and methods
- Principles of method if other than guideline:
- Intravenous application to cats
- GLP compliance:
- not specified
Test material
- Reference substance name:
- 2,3-xylidine
- EC Number:
- 201-755-0
- EC Name:
- 2,3-xylidine
- Cas Number:
- 87-59-2
- Molecular formula:
- C8H11N
- IUPAC Name:
- 2,3-dimethylaniline
Constituent 1
Test animals
- Species:
- cat
- Strain:
- not specified
- Sex:
- not specified
Administration / exposure
- Route of administration:
- other: no data
- Vehicle:
- not specified
- Details on exposure:
- intraveneous
- Doses:
- 30 mg/kg
- No. of animals per sex per dose:
- no data
- Control animals:
- not specified
Results and discussion
Effect levels
- Sex:
- not specified
- Dose descriptor:
- other: conc. of methemoglobinemia
- Effect level:
- ca. 20.2 other: %
- Based on:
- not specified
Applicant's summary and conclusion
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
