Registration Dossier
Registration Dossier
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EC number: 201-755-0 | CAS number: 87-59-2
Endpoint summary
Administrative data
Description of key information
Acut oral toxicity male rats: 930 mg/kg (BUA-Stoffberichte)
Acut oral toxicity male mouse: 1070 mg/kg (BUA-Stoffberichte)
Methemoglobinemia after intraveneous application 20,2% in first 5 h
Key value for chemical safety assessment
Acute toxicity: via oral route
Endpoint conclusion
- Dose descriptor:
- LD50
- Value:
- 930 mg/kg bw
Additional information
Only limited data is available on acute toxicity. The values for oral toxicity indicate that the 2,3 -xylidine is less toxic than the 2,4 -isomer. 2,3-xylidine was found to cause methemoglobinemia.
Justification for classification or non-classification
As other xylidines (except 2,4-xylidine) 2,3-xylidine is found to be harmful at oral application. This would justify a classification as acut tox 4 (oral). But since available data are limited and because of lack of datas for dermal and inhalative route a deviation from EU group classification for xylidines seem to be not justified.
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