Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Toxicological information

Direct observations: clinical cases, poisoning incidents and other

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Administrative data

Endpoint:
direct observations: clinical cases, poisoning incidents and other
Type of information:
experimental study
Adequacy of study:
other information
Reliability:
3 (not reliable)
Rationale for reliability incl. deficiencies:
other: Method not validated

Data source

Reference
Title:
No information
Author:
Bogaards J.J. et al., Toxicol. Appl. Pharmacol. 132, 44-52|(1995)

Materials and methods

Principles of method if other than guideline:
Use of techniques ad HPLC and EROD to assess in the human cytochrome P450 enzyme selectivities in the oxidation of chlorinated benzenes
GLP compliance:
not specified

Test material

Constituent 1
Chemical structure
Reference substance name:
1,2,4-trichlorobenzene
EC Number:
204-428-0
EC Name:
1,2,4-trichlorobenzene
Cas Number:
120-82-1
Molecular formula:
C6H3Cl3
IUPAC Name:
1,2,4-trichlorobenzene
Details on test material:
TS-Freetext:
highest available quality (no other information)

Results and discussion

Applicant's summary and conclusion