Registration Dossier
Registration Dossier
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EC number: 215-249-2 | CAS number: 1314-96-1
Endpoint summary
Administrative data
Description of key information
Based on worst case considerations strontium sulfide is corrosive to skin and eye, since the pH of a 1% solution is 12.6.
Key value for chemical safety assessment
Skin irritation / corrosion
Endpoint conclusion
- Endpoint conclusion:
- no study available
Eye irritation
Endpoint conclusion
- Endpoint conclusion:
- no study available
Respiratory irritation
Endpoint conclusion
- Endpoint conclusion:
- no study available
Additional information
Skin irritation
No studies on skin irritation have been performed with the substance and none are proposed, based on scientific considerations and for reasons of animal welfare. In accordance with section 8.1, column 2, Annex VII of regulation (EC) 1907/2006), the in-vitro eye irritation study does not need to be conducted as the available information indicates that the criteria are met for classification as corrosive to the skin. In accordance with section 8.1.1, column 2, Annex VIII of regulation (EC) 1907/2006), the in-vivo eye irritation study does not need to be conducted as the substance is a strong base (pH≥11.5).
Eye irritation
No studies on eye irritation have been performed with the substance and none are proposed, based on scientific considerations and for reasons of animal welfare. In accordance with section 8.2, column 2, Annex VII of regulation (EC) 1907/2006), the in-vitro eye irritation study does not need to be conducted as the available information indicates that the criteria are met for classification as corrosive to the eyes. In accordance with section 8.2.1, column 2, Annex VIII of regulation (EC) 1907/2006), the in-vivo eye irritation study does not need to be conducted as the substance is classified as corrosive to the skin and it is provided that the registrant classified the substance as eye irritant. Furthermore, the substance is a strong base (pH≥11.5).
Effects on skin irritation/corrosion: corrosive
Effects on eye irritation: corrosive
Justification for classification or non-classification
Skin irritation:
The test substance should be classified as corrosive to the skin by worst case (pH >11.5). Therefore, the in vivo skin irritation was not conducted due to animal welfare. Hence, the substance has to be classified as skin corrosive 1A substance and labeled with H314: Causes severe skin burns and eye damage.
Eye irritation:
The test substance is classified as corrosive to the skin by default. Therefore, the in vivo eye irritation was not conducted due to animal welfare. Hence, the substance has to be classified as eye damage 1 and labeled with H318: Causes serious eye damage which was already covered by the labeling H314: Causes severe skin burns and eye damage.
Respiratory irritation:
The classification as respiratory irritant is normally covered under the endpoint specific target organ toxicity- single exposure and repeated exposure. For substances and mixtures classified as skin corrosive, the additional labelling EUH071: Corrosive to the respiratory tract should be used due to the fact that no acute inhalation test data is available.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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