Registration Dossier
Registration Dossier
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EC number: 200-853-0 | CAS number: 75-24-1
Endpoint summary
Administrative data
Link to relevant study record(s)
Description of key information
Written toxicokinetics assessment
Key value for chemical safety assessment
Additional information
It is not possible to evaluate the toxicokinetics of trimethylaluminium as the substance reacts with water to produce aluminium hydroxide and methane or methanol and reacts spontaneously in air to form aluminium oxide, carbon dioxide and water. Therefore, the toxicokinetics effects of aluminium oxide and aluminium hydroxide need to be considered when evaluating the effects of exposure to trimethylaluminium.
Absorption of aluminium by the oral, inhalation and dermal routes is predicted to be low. Filtration in the kidneys is the main route by which systemic aluminium is excreted.Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
