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Long-term toxicity to aquatic invertebrates

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Link to relevant study record(s)

Description of key information

One valid long term daphnia study performed as a limit test according to OECD 211 and GLP is available. The NOEC after 21d was determined to be > 12 mg/l. 

Key value for chemical safety assessment

Fresh water invertebrates

Fresh water invertebrates
Dose descriptor:
Effect concentration:
12 mg/L

Additional information

In a 21-day chronic toxicity study, Daphnia magna were exposed to Propanamide, 2-hydroxy-N,N-dimethyl at

nominal concentrations of 0 (control) and 12 mg/L under static renewal conditions in accordance with the OECD 211 guideline. The water pH, temperature and dissolved O2 were within acceptable guideline specifications. Mortality, reproduction and sublethal effects were observed daily. No effect on mortality and reproduction or any adverse effects on additional endpoints (i.e. growth, immobile young, time to first brood, or aborted eggs) were observed in any of the test treatments. An EC0 ≥12 mg/L was deviated for reproduction and mortality.