Registration Dossier

Data platform availability banner - registered substances factsheets

Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Toxicological information

Developmental toxicity / teratogenicity

Currently viewing:

Administrative data

developmental toxicity
Developmental Toxicity model (CAESAR) 2.1.7
Type of information:
Adequacy of study:
supporting study
Study period:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
results derived from a valid (Q)SAR model and falling into its applicability domain, with adequate and reliable documentation / justification

Data source

Materials and methods

Test guideline
according to guideline
other: Developmental Toxicity model (CAESAR) 2.1.7
Version / remarks:
not applicable
Principles of method if other than guideline:
The model implements a virtual library of toxicant compounds. The CAESAR QSAR model has been developed with the aim to minimize false negatives in order to make them more usable for REACH.

Test material

Constituent 1
Chemical structure
Reference substance name:
Butyl 10-oxooctadecanoate
Molecular formula:
Butyl 10-oxooctadecanoate
Test material form:
liquid: viscous

Results and discussion

Any other information on results incl. tables


Experimental value: -

Predicted developmental toxicity activity: NON-Toxicant

Reliability: the predicted compound is into the Applicability Domain of the model

Remarks: none

Global AD Index

AD index = 0.912

Explanation: the predicted compound is into the Applicability Domain of the model.

Similar molecules with known experimental value

Similarity index = 0.831

Explanation: strongly similar compounds with known experimental value in the training set have been found.

Accuracy of prediction for similar molecules

Accuracy index = 1

Explanation: accuracy of prediction for similar molecules found in the training set is good.

Applicant's summary and conclusion

This constituent (the most present in terms of percentage) resulted non toxicant