Registration Dossier
Registration Dossier
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EC number: 940-822-5 | CAS number: -
Endpoint summary
Administrative data
Description of key information
Additional information
Performing a bioaccumulation experiment on FAV-ES is technically hampered. As FAV-ES consists of a high (>30) number of constituents, the analytical identification of these constituens and their quantification in fish tissue is not straightforward. Therefore, the EpiSuite QSAR was used in order to gain information on the bioaccumulative potential of each of the identified constituents.
The QSAR results show that 31 of the 34 constituents identified in FAV-ES have estimated BCF values < 2000. The remaining 3 constituents (F1, C4 and C5) have estimated BCF values of 2460, 2052 and 2802, respectively.
Even though these estimated BCF values > 2000 indicate a potential for bioaccumulation, it has to be taken into account that the ester functions present in all FAV-ES constituents will be subject to hydrolysis under the influence of esterase and lipase enzymes present in the organism. As a consequence, an accumulation of the FAV-ES constituents in living organisms is unlikely. Therefore, none of the FAV-ES constituents are considered to have bioaccumulative potential.
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