Registration Dossier
Registration Dossier
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EC number: 201-944-8 | CAS number: 89-83-8
Additional toxicological data
Administrative data
- Endpoint:
- additional toxicological information
- Type of information:
- experimental study
- Adequacy of study:
- other information
- Reliability:
- 4 (not assignable)
- Rationale for reliability incl. deficiencies:
- other: early study (1956)
Data source
Reference
- Reference Type:
- publication
- Title:
- 3-Methyl-4-isopropylphenol studies on antiseptics
- Author:
- Izeki M
- Year:
- 1 956
- Bibliographic source:
- Osaka Shiritsu Daigaku Igaku Zasshi 5, 111-118
Materials and methods
- Type of study / information:
- effects of thymol on vital functions
- Principles of method if other than guideline:
- clinicals signs of intravenous injection of thymol to rabbits
- GLP compliance:
- no
Test material
- Reference substance name:
- Thymol
- EC Number:
- 201-944-8
- EC Name:
- Thymol
- Cas Number:
- 89-83-8
- Molecular formula:
- C10H14O
- IUPAC Name:
- 5-methyl-2-(propan-2-yl)phenol
- Details on test material:
- no data
Constituent 1
Results and discussion
Any other information on results incl. tables
5 mg/kg bw thymol i.v. to rabbits: transient fall of blood pressure, inhibition of respiration
Applicant's summary and conclusion
- Executive summary:
- Intravenous injection of 5 mg/kg bw thymol to rabbits produces a transient fall of blood pressure and the inhibition of respiration
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