Registration Dossier
Registration Dossier
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EC number: 272-379-2 | CAS number: 68815-51-0
Endpoint summary
Administrative data
Description of key information
Murine Local Lymph Node Assay: sensitising (EC3 = 1%)
Key value for chemical safety assessment
Skin sensitisation
Endpoint conclusion
- Endpoint conclusion:
- adverse effect observed (sensitising)
- Additional information:
In the key study that was performed according to OECD guideline 429 in compliance with GLP the substance showed a skin sensitising effect (BASF SE, 2009). The threshold concentration for sensitisation induction was < 3%. The estimated concentration that leads to the SI of 1.5 for cell count (EC 1.5) and the estimated concentration that leads to the SI of 3.0 for 3H-thymidine incorporation (EC 3) was calculated by semi-logarithmical regression from the results of all concentrations to be about 1%, respectively.
Respiratory sensitisation
Endpoint conclusion
- Endpoint conclusion:
- no study available
- Additional information:
There are no data available concerning respiratory sensitisation.
Justification for classification or non-classification
GHS classification according to Annex I 1272/2008 CLP (EU GHS):
- Skin sensitisation Cat. 1A
- Respiratory sensitisation: data lacking
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