Registration Dossier
Registration Dossier
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EC number: 267-023-8 | CAS number: 67762-55-4
Short-term toxicity to fish
Administrative data
Link to relevant study record(s)
Description of key information
Under the conditions of this study, the 96 hour LL50 was determined to be greater than 100 mg/L loading rate WAF. The No Observed Effect Loading rate was 100 mg/L loading rate WAF.
Key value for chemical safety assessment
Fresh water fish
Fresh water fish
- Dose descriptor:
- LC50
- Effect concentration:
- 100 mg/L
Additional information
The acute toxicity potential of the test material to Oncorhynchus mykiss was investigated in the key study in accordance with the standardised guidelines OECD 203 and EU Method C.1 under GLP conditions. It was assigned a reliability score of 1 in accordance with the criteria set forth in Klimisch (1997).
Seven fish were exposed to a Water Accommodated Fraction (WAF) of the test material, at a single nominal loading rate of 100 mg/L for a period of 96 hours at a temperature of 13 to 15 °C under semi-static test conditions. The number of mortalities and any sub-lethal effects of exposure in each test and control vessel were determined 3 and 6 hours after the start of exposure and then daily throughout the test until termination after 96 hours.
Under the conditions of this study, the 96 hour LL50 was determined to be greater than 100 mg/L loading rate WAF. The No Observed Effect Loading rate was 100 mg/L loading rate WAF.
It was considered unnecessary and unrealistic to test at loading rates in excess of 100 mg/L.
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