Registration Dossier
Registration Dossier
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EC number: 200-064-1 | CAS number: 50-78-2
Toxicity to birds
Administrative data
- Endpoint:
- short-term toxicity to birds: acute oral toxicity test
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 1983
- Reliability:
- 4 (not assignable)
- Rationale for reliability incl. deficiencies:
- other: Citation of previous publications not checked because of poor relevance
Data source
Reference
- Reference Type:
- publication
- Title:
- The acute oral toxicity, repellency, and hazard potential of 998 chemicals to one or more species of wild and domestic birds
- Author:
- Schafer EW et al
- Year:
- 1 983
- Bibliographic source:
- Arch Environ Contam Toxicol, 12, 355-382)
Materials and methods
- Principles of method if other than guideline:
- Wild-trapped redwing blackbirds were preconditioned to captivity for 2 to 6 weeks, and were dosed by gavage with solutions of the test chemical in propylene glycol.
- GLP compliance:
- no
Test material
- Reference substance name:
- O-acetylsalicylic acid
- EC Number:
- 200-064-1
- EC Name:
- O-acetylsalicylic acid
- Cas Number:
- 50-78-2
- Molecular formula:
- C9H8O4
- IUPAC Name:
- 2-acetoxybenzoic acid
- Test material form:
- solid: crystalline
- Details on test material:
- Purchased or solicited from a producer.
Constituent 1
- Dose method:
- gavage
- Analytical monitoring:
- no
- Vehicle:
- yes
Test organisms
- Test organisms (species):
- other: Agelaius phoeniceus
Study design
- Limit test:
- no
- Remarks:
- No precision in the publication checked, reference of method: Schafer EW (1972) Toxicol. Appl. Pharmacol. 21, 315
- No. of animals per sex per dose and/or stage:
- No data in the publication
Results and discussion
Effect levels
- Dose descriptor:
- LC50
- Effect level:
- 100 mg/kg bw
- Conc. / dose based on:
- test mat.
- Basis for effect:
- mortality
Any other information on results incl. tables
No indication on duration
Applicant's summary and conclusion
- Validity criteria fulfilled:
- not specified
- Conclusions:
- LC50 in Agelaius phoeniceus = 100 mg/kg bw
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