Registration Dossier
Registration Dossier
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EC number: 700-230-8 | CAS number: 3160-86-9
Endpoint summary
Administrative data
Description of key information
Key value for chemical safety assessment
Skin sensitisation
Endpoint conclusion
- Additional information:
No sensitization data are available for the PA6T salt [1,4-benzenedioic acid, compound with hexane-1,6-diamine (1:1)]. Data for component chemicals show no evidence for skin sensitization. While sensitization data for a related substance (Nylon 12/T salt [dodecanedioic acid, compound with hexane-1,6-diamine (1:1); CAS# 13188-60-8; EC# 236-143-2]) exists, it may not be relevant as diamines C6 chain length may be more likely to cause sensitization than hexamethylenediamine. Additionally, testing with PA66 salt [adipic acid, compound with hexane-1,6-diamine (1:1); CAS# 3323-53-3; EC# 222-037-3] shows that it is not a sensitizer. Therefore, PA6T salt is not expected to be a skin sensitizer.
References:
OECD SIDS (2004). OECD SIDS Dossier for Adipic Acid (CAS 124-04-9) (http://www.inchem.org/documents/sids/sids/124049.pdf).
OECD SIDS (2001). OECD SIDS Dossier for Terephthalic Acid (CAS 100-21-0) (http://www.chem.unep.ch/irptc/sids/OECDSIDS/100-21-0.pdf).
OECD SIDS (nd). OECD SIDS Dossier for Hexamethylenediamine (CAS 124-09-4) (http://www.inchem.org/documents/sids/sids/124094.pdf).
OECD SIDS (2003). OECD SIDS for Adipic Acid, Compound with Hexane-1,6-diamine (1:1) (CAS 3323-53-3) (http://www.chem.unep.ch/irptc/sids/OECDSIDS/3323533.pdf).
BASF (2014). Material Safety Data Sheet, AH-salt solution (http://www.plasticsportal.net/wa/EU/Catalog/ePlastics/doc4/BASF/PRD/30214804/.pdf?title=&asset_type=msds/pdf&language=EN&validArea=REG_EU&urn=urn:documentum:ProductBase_EU:09007af88001a52c.pdf).
Justification for classification or non-classification
Based on data from component chemicals and similar salts the test substance is not expected to be a skin sensitizer. Therefore the test substance is not classified for skin sensitization to according to EU Directive 67/548/EEC and EU Classification, Labelling and Packaging of Substances and Mixtures (CLP) Regulation (EC) No. 1272/2008.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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