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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Endpoint:
toxicity to microorganisms, other
Type of information:
experimental study
Adequacy of study:
key study
Study period:
November 1995- April 1996
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
study well documented, meets generally accepted scientific principles, acceptable for assessment

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
1996

Materials and methods

Test guideline
Qualifier:
according to guideline
Guideline:
other: Richtlinie 87/302/EWG
Principles of method if other than guideline:
method: Other: according to guideline RL 87/302/EWG Respiration inhibition for activated sludge.
GLP compliance:
not specified

Test material

Constituent 1
Chemical structure
Reference substance name:
-
EC Number:
421-690-3
EC Name:
-
Cas Number:
203515-86-0
Molecular formula:
C14H21N3O6 . ClH
IUPAC Name:
5-amino-N1,N3-bis(2,3-dihydroxypropyl)benzene-1,3-dicarboxamide hydrochloride
Constituent 2
Reference substance name:
3,5-bis[(2,3-dihydroxypropyl)carbamoyl]aniliniumchloride
IUPAC Name:
3,5-bis[(2,3-dihydroxypropyl)carbamoyl]aniliniumchloride
Details on test material:
- Name of test material (as cited in study report): ABA-HCl
- Molecular formula (if other than submission substance):
- Molecular weight (if other than submission substance):
- Smiles notation (if other than submission substance):
- InChl (if other than submission substance):
- Structural formula attached as image file (if other than submission substance): see Fig.
- Substance type:
- Physical state: Powder
- Analytical purity: ≥98.5
- Impurities (identity and concentrations):
- Composition of test material, percentage of components:
- Isomers composition:
- Purity test date:
- Lot/batch No.: S-31308
- Expiration date of the lot/batch:
- Radiochemical purity (if radiolabelling):
- Specific activity (if radiolabelling):
- Locations of the label (if radiolabelling):
- Expiration date of radiochemical substance (if radiolabelling):
- Stability under test conditions:
- Storage condition of test material:
- Other:

Test organisms

Test organisms (species):
activated sludge

Study design

Test type:
other: aerobic
Total exposure duration:
3 h

Test conditions

Test temperature:
20oC
Reference substance (positive control):
yes
Remarks:
3,5 -Dichlorphenol

Results and discussion

Effect concentrationsopen allclose all
Duration:
3 h
Dose descriptor:
NOEC
Effect conc.:
< 1.56 g/L
Duration:
3 h
Dose descriptor:
EC10
Effect conc.:
3 g/L
Duration:
3 h
Dose descriptor:
EC50
Effect conc.:
> 22 g/L

Applicant's summary and conclusion

Conclusions:
Respiration inhibition (for activated sludge): EC50 > 22gr/l.