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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Ecotoxicological information

Long-term toxicity to aquatic invertebrates

Administrative data

Endpoint:
long-term toxicity to aquatic invertebrates
Type of information:
experimental study
Adequacy of study:
key study
Study period:
July, 2001
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
study well documented, meets generally accepted scientific principles, acceptable for assessment

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2001

Materials and methods

Test guideline
Qualifier:
according to guideline
Guideline:
OECD Guideline 211 (Daphnia magna Reproduction Test)
GLP compliance:
yes (incl. QA statement)

Test material

Constituent 1
Chemical structure
Reference substance name:
-
EC Number:
421-690-3
EC Name:
-
Cas Number:
203515-86-0
Molecular formula:
C14H21N3O6 . ClH
IUPAC Name:
5-amino-N1,N3-bis(2,3-dihydroxypropyl)benzene-1,3-dicarboxamide hydrochloride

Study design

Test type:
semi-static
Water media type:
freshwater
Total exposure duration:
21 d

Results and discussion

Effect concentrationsopen allclose all
Duration:
21 d
Dose descriptor:
EC50
Effect conc.:
> 100 mg/L
Basis for effect:
reproduction
Duration:
21 d
Dose descriptor:
NOEC
Effect conc.:
100 mg/L

Any other information on results incl. tables

Comments:

The analytically measured test item concentration in the test medium of the highest test concentration of nominal 100 mg/l was in the range of 98 to 100%. The test item was

sufficiently stable during the test medium renewal periods

of 2 and 3 days. Therefore, the test results are related to

nominal concentrations of the test item.

Applicant's summary and conclusion

Conclusions:
In conclusion, the test item ABA-HCl had no toxic effects on the survival rates and reproduction rates of daphnids up to 100 mg/l.