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EC number: 618-883-1 | CAS number: 92878-95-0
Skin sensitisation
Administrative data
- Endpoint:
- skin sensitisation: in vivo (LLNA)
- Type of information:
- experimental study
- Adequacy of study:
- other information
- Study period:
- 15 July - 11 August 2009
- Reliability:
- 1 (reliable without restriction)
Data source
Materials and methods
Test guidelineopen allclose all
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 429 (Skin Sensitisation: Local Lymph Node Assay)
- Qualifier:
- according to guideline
- Guideline:
- EU Method B.42 (Skin Sensitisation: Local Lymph Node Assay)
- Qualifier:
- according to guideline
- Guideline:
- EPA OPPTS 870.2600 (Skin Sensitisation)
- Principles of method if other than guideline:
- Molecular formula C10H12ClNO4
Molecular weight 245.66
CAS Number 92878-95-0
Description Slightly yellow powder
Batch 18238702
Purity 99.8%
Test substance storage At room temperature protected from light
Stability under storage conditions Stable - GLP compliance:
- yes
- Type of study:
- mouse local lymph node assay (LLNA)
Test material
- Reference substance name:
- 2-(3-chloropropoxy)-1-methoxy-4-nitrobenzene
- EC Number:
- 618-883-1
- Cas Number:
- 92878-95-0
- Molecular formula:
- C10H12ClNO4
- IUPAC Name:
- 2-(3-chloropropoxy)-1-methoxy-4-nitrobenzene
Constituent 1
In vivo test system
Test animals
- Species:
- mouse
- Strain:
- CBA
- Sex:
- female
Study design: in vivo (LLNA)
- Vehicle:
- propylene glycol
- No. of animals per dose:
- 20 females (nulliparous and non-pregnant), five females per group.
Results and discussion
Applicant's summary and conclusion
- Interpretation of results:
- not sensitising
- Remarks:
- Migrated information
- Conclusions:
- Based on these results WAY-188471 does not have to be classified and has no obligatory labeling requirement for sensitization by skin contact according to the recommendations made in the test guidelines, the Globally Harmonized System of Classification and Labeling of Chemicals (GHS) of the United Nations (2007) and the Regulation (EC) No 1272/2008 on classification, labeling and packaging of substances and mixtures.
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