Registration Dossier
Registration Dossier
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EC number: 939-692-2 | CAS number: 1474044-73-9
Endpoint summary
Administrative data
Description of key information
Additional information
Strong bioaccumulation in aquatic organisms is unlikely for substances (like the UVCB substance '1,3,4-Thiadiazolidine-2,5-dithione, reaction products with hydrogen peroxide and tert-dodecanethiol' (no CAS#, no EC#) exhibiting a partition coefficient (logPow) < 4.5 or > 6. The partition coefficient of log Pow >9.4 was determined on the supporting substance '1,3,4-Thiadiazolidine-2,5-dithione, reaction products with hydrogen peroxide and tert-nonanethiol' by High Performance Liquid Chromatography (HPLC) according to OECD 117 / EU Method A.8 (whereat the result should be also applicable for the closely related substance ‘1,3,4-Thiadiazolidine-2,5-dithione, reaction products with hydrogen peroxide and tert-dodecanethiol’).
The aquatic bioconcentration factor (BCF) of 1,3,4-Thiadiazole, 2,5-bis(tert-dodecyldithio)- (CAS# 50530-43-3) [= one of the main constituents of the UVCB substance '1,3,4-Thiadiazolidine-2,5-dithione, reaction products with hydrogen peroxide and tert-dodecanethiol' (no CAS#, no EC#)] was predicted with the US-EPA software BCFBAF v3.01. The most relevant method, the regression-based one, revealed a BCF of 3.16 L/kg. This value indicates that strong bioaccumulation in aquatic organisms is unlikely.
Terrestrial bioaccumulation is no mandatory requirement under REACH and the chemical safety assessment indicates no need for further testing. Thus, the endpoint is fulfilled.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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