Registration Dossier
Registration Dossier
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EC number: 404-360-3 | CAS number: 119313-12-1 CG 25-369; IRGACURE 369; TK 11-319
Toxicity to aquatic algae and cyanobacteria
Administrative data
- Endpoint:
- toxicity to aquatic algae and cyanobacteria
- Type of information:
- (Q)SAR
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: ECOSAR (a module of EPISuite) is a validated QSAR tool
- Justification for type of information:
- QSAR prediction: migrated from IUCLID 5.6
Data source
Reference
- Reference Type:
- other: Body Responsible for test
- Title:
- Unnamed
- Report date:
- 1991
Materials and methods
Test guideline
- Guideline:
- other: REACH guidance on QSARs
Test material
- Reference substance name:
- 2-benzyl-2-dimethylamino-4'-morpholinobutyrophenone
- EC Number:
- 404-360-3
- EC Name:
- 2-benzyl-2-dimethylamino-4'-morpholinobutyrophenone
- Cas Number:
- 119313-12-1
- Molecular formula:
- C23H30N2O2
- IUPAC Name:
- 2-benzyl-2-(dimethylamino)-1-[4-(morpholin-4-yl)phenyl]butan-1-one
- Details on test material:
- Smiles code: CN(C)C(Cc1ccccc1)(CC)C(=O)c2ccc(cc2)N3CCOCC3
Constituent 1
Results and discussion
Effect concentrations
- Duration:
- 96 h
- Dose descriptor:
- EC50
- Effect conc.:
- < 1 mg/L
- Remarks on result:
- other: QSAR estimation
Applicant's summary and conclusion
- Validity criteria fulfilled:
- not applicable
- Conclusions:
- It is assumed that the substance, or the products of photolysis, as very toxic to aquatic organisms
- Executive summary:
It is assumed that the substance, or the products of photolysis, is very toxic to aquatic organisms based on the result to fish and aquatic invertebrates. Modelling with ECOSAR (part of EPISuite) confirms the high expected toxicity.
The study is not possible to perform and was not conducted as part of the original notification.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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