Registration Dossier
Registration Dossier
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EC number: 261-858-1 | CAS number: 59690-88-9
Developmental toxicity / teratogenicity
Administrative data
- Endpoint:
- developmental toxicity
- Type of information:
- calculation (if not (Q)SAR)
- Remarks:
- Migrated phrase: estimated by calculation
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
Data source
Reference
- Reference Type:
- other: Authoritative data base
- Title:
- Danish QSAR study for CAS No.: 59690-88-9
- Author:
- Danish EPA Model
- Year:
- 2 012
- Bibliographic source:
- QSAR predictions by Danish Environmental Protection Agency (EPA)model powered by OASIS database:- Commercial
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- other: modelling database
- Principles of method if other than guideline:
- Teratogenicity (human). Multicase model.
- GLP compliance:
- no
Test material
- Reference substance name:
- (3-aminophenyl)uronium chloride
- EC Number:
- 261-858-1
- EC Name:
- (3-aminophenyl)uronium chloride
- Cas Number:
- 59690-88-9
- Molecular formula:
- C7H9N3O.ClH
- IUPAC Name:
- (NZ)-3-amino-N-[amino(hydroxy)methylidene]anilinium chloride
- Details on test material:
- - Name of test material : (3-aminophenyl)uronium chloride
Constituent 1
Test animals
- Species:
- other: human
- Strain:
- not specified
Administration / exposure
- Type of inhalation exposure (if applicable):
- not specified
- Vehicle:
- not specified
Results and discussion
Results: maternal animals
Effect levels (maternal animals)
- Basis for effect level:
- other: effect type not specified
Results (fetuses)
Fetal abnormalities
- Abnormalities:
- not specified
Overall developmental toxicity
- Developmental effects observed:
- not specified
Applicant's summary and conclusion
- Conclusions:
- Teratogenicity of (3-aminophenyl)uronium chloride is estimated to give negative result.
- Executive summary:
Teratogenicity of (3-aminophenyl)uronium chloride is estimated to give negative result.
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