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EC number: 255-460-7 | CAS number: 41611-76-1
Long-term toxicity to aquatic invertebrates
Administrative data
Link to relevant study record(s)
Description of key information
21d-EC10 (Daphnia magna) > solubility limit; iSafeRat® High-Accuracy-Quantitative Structure-Activity Relationship; KREATiS (2022).
Key value for chemical safety assessment
Additional information
To strengthen the reliability of the HA-QSAR prediction and the category approach, one experimental chronic daphnia study is available on the source substance, Solvent Blue 104 (CAS No 116-75-6). In addition, a testing proposal for a chronic daphnia study is requested on the source substance, Solvent Green 28 (CAS No 4851-50-7). Both substances are members of the category. See the category approach justification document, attached in section 13, for further details.
Global overview of the category approach for the endpoint:
| Solvent Violet 36 | Solvent Green 3 | Reinblau RLW | Reinblau BLW | Solvent Blue 104# | Solvent Green 28 | |
Long-term toxicity to aquatic invertebrates | 21d-EC10 (D.magna) > solubility limit* | 21d-EC10 (D.magna) > solubility limit* | 21d-EC10 (D.magna) > solubility limit* | 21d-EC10 (D.magna) > solubility limit* | 21d-NOEC (D.magna) ³ 1.0 mg/L (nominal)$
21d-EC10 (D.magna) > solubility limit* | Testing proposal (OECD TG 211) | |
# not registered by LANXESS, data with letter of access
* iSafeRat® High Accuracy QSAR predictions (KREATiS, 2022)
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