Registration Dossier

Diss Factsheets

Administrative data

Key value for chemical safety assessment

Genetic toxicity in vitro

Description of key information

Pigment Brown 41 (nano form): Mutagenicity in bacteria: Negative (Ames; Analogue substance: Pigment Red 242 (nano form): Negative (Ames, CA)


Analogue substance: Pigment Red 166 (not specified form): Negative (Ames, OECD 476, OECD 474)


Analogue substance: Pigment Red 144 (nano and not specified form): Negative (Ames)


Cytogenicity in mammaial cells: Negative


Gene mutation in mammalian cells: Negative

Endpoint conclusion
Endpoint conclusion:
no adverse effect observed (negative)

Genetic toxicity in vivo

Description of key information

Analogue substance Pigment Red 166 (not specified form): Negative (MN)

Endpoint conclusion
Endpoint conclusion:
no adverse effect observed (negative)

Additional information

Justification for classification or non-classification

Classification, Labelling, and Packaging Regulation (EC) No. 1272/2008


The available experimental test data are reliable and suitable for classification purposes under Regulation 1272/2008. As a result the substance is not considered to be classified for mutagenicity under Regulation (EC) No. 1272/2008, as amended for the third time in Directive EC 618/2012.