N,N'-(2,5-dichloro-1,4-phenylene)bis[4-[[2-chloro-5-(trifluoromethyl)phenyl]azo]-3-hydroxynaphthalene-2-carboxamide]

Nanomaterial dustiness

Administrative data

Endpoint:

nanomaterial dustiness

Type of information:

experimental study

Adequacy of study:

key study

Study period:

2020

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

test procedure in accordance with national standard methods

Remarks:

according to DIN EN 17199-3

Data source

Reference

Reference Type:

study report

Title:

Unnamed

Year:

2020

Report date:

2020

Materials and methods

Test guideline

Qualifier:

according to guideline

Guideline:

other: DIN EN 17199-3

Version / remarks:

measurement of dustiness of bulk materials that contain or release respirable NOAA or other respirable particles - Part 3: Continuous drop method

Deviations:

yes

Remarks:

test conditions (temperature, humidity) due to laboratory environment; 1 meaurement performed

GLP compliance:

no

Type of method:

continuous drop

Sampling:

The test material was used without further treatment (e.g. drying). 48.9 g (249.5 cm3) test material are used for the measurement, dosing rate: 4.89 g/min

Test material

Test material information

Constituent 1

Reference substance name:

N,N'-(2,5-dichloro-1,4-phenylene)bis[4-[[2-chloro-5-(trifluoromethyl)phenyl]azo]-3-hydroxynaphthalene-2-carboxamide]

EC Number:

257-776-0

EC Name:

N,N'-(2,5-dichloro-1,4-phenylene)bis[4-[[2-chloro-5-(trifluoromethyl)phenyl]azo]-3-hydroxynaphthalene-2-carboxamide]

Cas Number:

52238-92-3

Molecular formula:

C42H22Cl4F6N6O4

IUPAC Name:

N,N'-(2,5-dichloro-1,4-phenylene)bis(4-{[2-chloro-5-(trifluoromethyl)phenyl]diazenyl}-3-hydroxy-2-naphthamide)

Test material form:

solid: nanoform, no surface treatment

Details on test material:

none

Results and discussion

Dustiness index

Dustiness index 1

Key result

Mean:

97 805.5 other: 1/mg

Remarks on result:

other: dustiness index as number of airborne particles per mg in the nanoscale (10 nm - 100 nm)

Dustiness index 2

Mean:

9 023.9 other: N/cm3

Remarks on result:

other: number of airborne nanoparticles per cm3

Any other information on results incl. tables

measurement duration: 10 min

temperature: 19°C, rel. air humidity 51 %

The cleaned, almost particle-free air had a total particle count of 5 particles/cm³ in the range of 10 nm - 417 nm, the nanoscale fraction (10 - 100 nm) contained 2 particles/cm³.

table 1: summary SMPS (sanning mobility particle sizer)

Range [nm]	Mean [nm]	Concentration [N/cm^3]	ICD[1/mg]	ECD[1/mg x s]
10 - 100	46.3	9023.9	97805.5	163.0
100 - 417	204.8	5806.8	62937.2	104.9
10 - 417	108.3	14830.8	160742.8	267.9

I_CD: dustiness index as number of airborne particles per mg

E_CD: emission rate as number of particles per mg per second

mean: average particle diameter in nm

N: number of airborne particles

table 2: summary OPS (optical particle sizer)

Range [µm]	Mean [µm]	Concentration [N/cm^3]	ICD[1/mg]	ECD[1/mg x s]
0.3 - 10	5.1	30.5	330.6	0.6

Applicant's summary and conclusion

Executive summary:

The dusting behaviour of the test material was investigated using DIN EN 17199 -3: 2019 -12 "workplace exposure - measurement of dustiness of bulk materials that contain or release respirable nano objects and their aggregates and agglomerates or other respirable particles- Part 3: Copntinuous drop method".

The dust released by the falling test material was measured by a scanning mobility particle sizer (SMPS, 10 - 417 nm) and an optical particle sizer (3 - 10 µm). The counterflow was provided by cleaned, almost particle-free air.

The SMPS counted 9023.9 particles per cm³ (in the nanoscale (10 - 100 m)

corresponding to a dustiness index of 97805.5 particles per mg (in the nanoscale (10 - 100 nm).

The mean size of the nanoparticles was 46.3 nm (in the nanoscale 10 - 100 nm).

The SMPS counted 14830.8 particles per cm³(in the nanoscale (10 - 417 m)

corresponding to a dustiness index of 160742.8 particles per mg (in the nanoscale (10 - 417 nm).

The mean size of the nanoparticles was 108.3 nm (in the nanoscale 10 - 417 nm).

The OPS (0.3 - 10 µm) counted 30.5 particles per cm³ corresponding to a dustiness index of 330.6 particles per mg. The mean size of the particles was 5.1 µm.