pregnant-women-protection

Protection of Pregnant and Breastfeeding Workers Directive, Annex I+II

EU. Chemical Agents: Annexes I & II, Directive 92/85/EEC on Pregnant Workers, 28 November 1992 (updated by table 3 of Annex VI to CLP, 5 October 2018)

This list contains a non-exhaustive inventory of substances to which pregnant workers and workers who have recently given birth or are breastfeeding may not be exposed. Employers are obligated to prevent the exposure of these workers to any agents that may have adverse health effects on either mother or child. The inventory originates from Table 3 of Annex VI to the CLP.

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Last updated 19 April 2024. Database contains 2100 unique substances/entries.
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Substance Name
EC No.
CAS No.
CLP (1272/2008) CMRs
ECCAR Directive 2004/37/EC
 
1,2-dimethoxyethane; ethylene glycol dimethyl ether; EGDME
203-794-9
110-71-4
Repr. 1B
yes
 Details
1,2-dimethylhydrazine
-
540-73-8
Carc. 1B
yes
 Details
1,2-epoxybutane
203-438-2
106-88-7
Carc. 2
Details
1,3,5-triazine-2,4,6-triamine; melamine
203-615-4
108-78-1
Carc. 2
Details
1,3,5-trioxan; trioxymethylene
203-812-5
110-88-3
Repr. 2
Details
1,3,5-tris(oxiranylmethyl)-1,3,5-triazine-2,4,6(1H,3H,5H)-trione; TGIC
219-514-3
2451-62-9
Muta. 1B
yes
 Details
1,3,5-tris-[(2S and 2R)-2,3-epoxypropyl]-1,3,5-triazine-2,4,6-(1H,3H,5H)-trione
TEPIC-H
423-400-0
59653-74-6
Muta. 1B
yes
 Details
1,3-bis(vinylsulfonylacetamido)propane
H-604
428-350-3
93629-90-4
Muta. 2
Details
1,3-butadiene; buta-1,3-diene
203-450-8
106-99-0
Carc. 1A; Muta. 1B
yes
 Details
1,3-dichloro-2-propanol
202-491-9
96-23-1
Carc. 1B
yes
 Details
1,3-diphenylguanidine
203-002-1
102-06-7
Repr. 2
Details
1,3-propanesultone; 1,2-oxathiolane 2,2-dioxide
214-317-9
1120-71-4
Carc. 1B
yes
 Details
1,4,5,8-tetraaminoanthra; quinone; C.I. Disperse Blue 1
219-603-7
2475-45-8
Carc. 1B
yes
 Details
1,4-Benzenediamine, N,N'-mixed Ph and tolyl derivs.
273-227-8
68953-84-4
Repr. 1B
yes
 Details
1,4-dichlorobenzene; p-dichlorobenzene
203-400-5
106-46-7
Carc. 2
Details
1,4-dichlorobut-2-ene
212-121-8
764-41-0
Carc. 1B
yes
 Details
1,4-dihydroxybenzene; hydroquinone; quinol
204-617-8
123-31-9
Carc. 2; Muta. 2
Details
1,4-dioxane
204-661-8
123-91-1
Carc. 1B
yes
 Details
1,5-naphthylenediamine
218-817-8
2243-62-1
Carc. 2
Details
1-(1-naphthylmethyl)quinolinium chloride
CIB R634
406-220-7
65322-65-8
Carc. 2; Muta. 2
Details
1-(2-amino-5-chlorophenyl)-2,2,2-trifluoro-1,1-ethanediol, hydrochloride [containing ≥ 0,1 % 4-chloroaniline (EC No 203-401-0)]
433-580-2
214353-17-0
Carc. 1B
yes
 Details
1-bromo-2-methylpropyl propionate
422-900-6
158894-67-8
Carc. 2
Details
1-bromo-3,4,5-trifluorobenzene
1-BROM-3,4,5-TRIFLUORBENZOL; 1-BROMO-3,4,5-TRIFLUOROBENZENE
418-480-9
138526-69-9
Carc. 2
Details
1-bromopropane; n-propyl bromide
203-445-0
106-94-5
Repr. 1B
yes
 Details
1-chloro-2,3-epoxypropane; epichlorhydrin
203-439-8
106-89-8
Carc. 1B
yes
 Details
1-chloro-4-nitrobenzene
202-809-6
100-00-5
Carc. 2; Muta. 2
Details
1-cyclopropyl-6,7-difluoro-1,4-dihydro-4-oxoquinoline-3-carboxylic acid
CHINOLONCARBONSÄURE 93-073; CP-70,335
413-760-7
93107-30-3
Repr. 2
Details
1-ethyl-1-methylmorpholinium bromide
MEM
418-250-8
65756-41-4
Muta. 2
Details
1-ethyl-1-methylpyrrolidinium bromide
MEP
418-200-5
69227-51-6
Muta. 2
Details
1-methyl-3-nitro-1-nitrosoguanidine
200-730-1
70-25-7
Carc. 1B
yes
 Details
1-vinyl-2-pyrrolidone
201-800-4
88-12-0
Carc. 2
Details
1-vinylimidazole
214-012-0
1072-63-5
Repr. 1B
yes
 Details
2,2',6,6'-tetrabromo-4,4'-isopropylidenediphenol; tetrabromobisphenol-A
201-236-9
79-94-7
Carc. 1B
yes
 Details
2,2'-((3,3', 5,5'-tetramethyl-(1,1'-biphenyl)-4,4'-diyl)-bis(oxymethylene))-bis-oxirane
EPIKOTE YX4000; EPIKOTE YX4000H; YX-4000
413-900-7
85954-11-6
Carc. 2
Details
2,2'-(nitrosoimino)bisethanol
214-237-4
1116-54-7
Carc. 1B
yes
 Details
2,2'-bioxirane; 1,2:3,4-diepoxybutane
215-979-1
1464-53-5
Carc. 1B; Muta. 1B
yes
 Details
2,2'-dichloro-4,4'-methylenedianiline; 4,4'-methylene bis(2-chloroaniline)
202-918-9
101-14-4
Carc. 1B
yes
 Details
2,2'-methylenediphenyl diisocyanate; diphenylmethane-2,2'-diisocyanate
219-799-4
2536-05-2
Carc. 2
Details
2,2-bis(bromomethyl)propane-1,3-diol
221-967-7
3296-90-0
Carc. 1B; Muta. 1B
yes
 Details
2,2-dibromo-2-nitroethanol
PERMACHEM N21
412-380-9
69094-18-4
Carc. 2
Details
2,2-dimethylpropan-1-ol, tribromo derivative
253-057-0
36483-57-5
Carc. 1B; Muta. 2
yes
 Details
2,3,4-trichlorobut-1-ene
219-397-9
2431-50-7
Carc. 2
Details
2,3,5,6-tetrafluoro-4-(methoxymethyl)benzyl (1R,3R)-2,2-dimethyl-3-[(1Z)-prop-1-en-1-yl]cyclopropanecarboxylate; epsilon-metofluthrin
-
240494-71-7
STOT SE 1
Details
2,3,5,6-tetrafluoro-4-(methoxymethyl)benzyl (Z)-(1R,3R)-3-(2-cyanoprop-1-enyl)-2,2-dimethylcyclopropanecarboxylate; epsilon-momfluorothrin
-
1065124-65-3
STOT SE 2
Details
2,3-dibromopropan-1-ol; 2,3-dibromo-1-propanol
202-480-9
96-13-9
Carc. 1B; Repr. 2
yes
 Details
2,3-dichloropropene; 2,3-dichloropropylene
201-153-8
78-88-6
Muta. 2
Details
2,3-dinitrotoluene
210-013-5
602-01-7
Carc. 1B; Muta. 2; Repr. 2
yes
 Details
2,3-epoxypropan-1-ol; glycidol; oxiranemethanol
209-128-3
556-52-5
Carc. 1B; Muta. 2; Repr. 1B
yes
 Details
2,3-epoxypropyl methacrylate; glycidyl methacrylate
203-441-9
106-91-2
Carc. 1B; Muta. 2; Repr. 1B
yes
 Details
2,3-epoxypropyl o-tolyl ether
218-645-3
2210-79-9
Muta. 2
Details
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