PBT assessment list

ECHA’s persistence, bioaccumulation and toxicity (PBT) assessment list includes the substances undergoing a PBT/vPvB assessment that have been brought for discussion to ECHA’s PBT Expert Group.

Explanatory note

Inclusion in the list means that an informal hazard assessment for PBT/vPvB properties either is under development or has been completed since February 2013.

For each substance, the table shows the assessing or evaluating Member State (submitter), the outcome from the assessment, and the date of the latest update to the list entry.

Other process details and hazard assessment outcome documents are also available and can be accessed through the ‘Details’ icon.

One possible outcome of such an assessment is that a substance is considered not to have PBT/vPvB properties.

If the outcome is that the substance is considered to have PBT/vPvB properties, confirmation through the formal risk management and decision-making processes is needed before any regulatory action can be taken due to these properties.

The intentions of authorities to submit a dossier to the formal REACH and CLP processes are notified through the Registry of Intentions. All biocidal active substances have to undergo a formal PBT assessment. You can see the status of biocides assessments on the Biocidal Active Substances page.

Disclaimer

The information and views set out in the PBT assessment list and in the hazard assessment outcome documents are those of the evaluating authority and do not necessarily reflect the position or opinion of the other Member States or ECHA. Neither ECHA nor the evaluating authority nor any person acting on either of their behalves may be held liable for the use, which may be made of the information contained therein. Statements made or information contained in the documents are without prejudice to any formal regulatory activities that ECHA or the Member States may initiate at a later stage. PBT assessments and their outcomes are compiled on the basis of information available by the date of the publication of the document.

Last updated 11 April 2024. Database contains 231 unique substances/entries.

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Latest update:

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Date of intention:

Date of hazard assessment:

Showing 1 - 25 of 236 results.

Substance name	EC / List no	CAS no	Authority	Outcome	Latest update
(ethoxymethoxy)cyclododecane	261-332-1	58567-11-6	Finland	not PBT not vPvB	07-Aug-2015	Details
1,1'-(ethane-1,2-diyl)bis[pentabromobenzene]	284-366-9	84852-53-9	Sweden	Under development under SEV	31-Jan-2020	Details
1,1'-(isopropylidene)bis[3,5-dibromo-4-(2,3-dibromo-2-methylpropoxy)benzene]	306-832-3	97416-84-7	Germany	not PBT not vPvB	20-Dec-2021	Details
1,1'-(isopropylidene)bis[3,5-dibromo-4-(2,3-dibromopropoxy)benzene]	244-617-5	21850-44-2	Germany	not PBT not vPvB	20-Dec-2021	Details
1,1'-(methylenedi-4,1-phenylene)bis(3-butylurea)	416-600-4	-	France	Under development	01-Apr-2015	Details
1,1'-[ethane-1,2-diylbisoxy]bis[2,4,6-tribromobenzene]	253-692-3	37853-59-1	Switzerland	vPvB	12-Jun-2023	Details
1,1,1,2,3,3-hexafluoro-2-[1,1,2,3,3,3-hexafluoro-2-[1,1,2,3,3,3-hexafluoro-2-[1,1,2,3,3,3-hexafluoro-2-(1,1,2,2,3,3,3-heptafluoropropoxy)propoxy]propoxy]propoxy]-3-(1,2,2,2-tetrafluoroethoxy)propane	-	37486-69-4	Germany	inconclusive	03-Aug-2021	Details
1,1,1,3,5,5,5-heptamethyl-3-[(trimethylsilyl)oxy]trisiloxane	241-867-7	17928-28-8	Norway	Under development under SEV	31-Jan-2020	Details
1,1,1,3,5,5,5-heptamethyltrisiloxane	217-496-1	1873-88-7	Norway	Under development	03-Nov-2022	Details
1,2,3,4-Tetrahydro-6-(1-phenylethyl)naphthalene	400-370-7	6196-98-1	Finland	Under development under SEV	08-Apr-2021	Details
1,2-benzenedicarboxylic acid, di-C10-12-branched alkyl esters	700-989-5	-	Denmark	not PBT not vPvB	15-Feb-2021	Details
1,2-Benzenedicarboxylic acid, di-C11-14-branched alkyl esters, C13-rich	271-089-3	68515-47-9	Denmark	not PBT	23-Jan-2020	Details
1,2-dichloro-4-(trichloromethyl)benzene	235-869-7	13014-24-9	Netherlands	postponed	10-Mar-2022	Details
1,3,4,6,7,8-hexahydro-4,6,6,7,8,8-hexamethylindeno[5,6-c]pyran	214-946-9	1222-05-5	France	Under development under SEV	30-Jun-2022	Details
1,3,5-tris(oxiranylmethyl)-1,3,5-triazine-2,4,6(1H,3H,5H)-trione	219-514-3	2451-62-9	Poland	not PBT not vPvB	02-Feb-2017	Details
1,4,5,6,7,7-hexachloro-8,9,10-trinorborn-5-ene-2,3-dicarboxylic anhydride	204-077-3	115-27-5	France	not PBT not vPvB	23-Jun-2022	Details
1,4-Benzenediamine, N,N'-mixed Ph and tolyl and xylyl derivs.	273-226-2	68953-83-3	Germany	Under development	01-Apr-2015	Details
1,4-Benzenediamine, N,N'-mixed Ph and tolyl derivs.	273-227-8	68953-84-4	Germany	inconclusive	24-Nov-2022	Details
1,4-Benzenediamine, N,N'-mixed tolyl and xylyl derivs.	270-820-3	68478-45-5	Germany	Under development	01-Apr-2015	Details
1,4-dioxane	204-661-8	123-91-1	Germany		21-Feb-2024	Details
1,6,7,8,9,14,15,16,17,17,18,18-Dodecachloropentacyclo[12.2.1.16,9.02,13.05,10]octadeca-7,15-diene (“Dechlorane Plus”™) covering any of its individual anti- and syn-isomers or any combination thereof show/hide (1S,2S,5R,6R,9S,10S,13R,14R)-1,6,7,8,9,14,15,16,17,17,18,18-Dodecachloropentacyclo[12.2.1.1⁶,⁹.0²,¹³.0⁵,¹⁰]octadeca-7,15-diene EC / List no: - \| CAS no: 135821-03-3 (1S,2S,5S,6S,9R,10R,13R,14R)-1,6,7,8,9,14,15,16,17,17,18,18-Dodecachloropentacyclo[12.2.1.1⁶,⁹.0²,¹³.0⁵,¹⁰]octadeca-7,15-diene EC / List no: - \| CAS no: 135821-74-8 1,6,7,8,9,14,15,16,17,17,18,18-dodecachloropentacyclo[12.2.1.16,9.02,13.05,10]octadeca-7,15-diene EC / List no: 236-948-9 \| CAS no: 13560-89-9 rel-(1R,4S,4aS,6aS,7S,10R,10aR,12aR)-1,2,3,4,7,8,9,10,13,13,14,14-dodecachloro-1,4,4a,5,6,6a,7,10,10a,11,12,12a-dodecahydro-1,4:7,10-dimethanodibenzo[a,e]cyclooctene EC / List no: - \| CAS no: - rel-(1R,4S,4aS,6aR,7R,10S,10aS,12aR)-1,2,3,4,7,8,9,10,13,13,14,14-dodecachloro-1,4,4a,5,6,6a,7,10,10a,11,12,12a-dodecahydro-1,4:7,10-dimethanodibenzo[a,e]cyclooctene EC / List no: - \| CAS no: -	-	-	United Kingdom	vPvB	10-Aug-2018	Details
1-(2-hydroxy-5-nonyl(branched)-phenyl)ethanone oxime	627-083-1	244235-47-0	Spain	not PBT not vPvB	22-Jun-2022	Details
1-(4-methyl-2-nitrophenylazo)-2-naphthol	219-372-2	2425-85-6	Germany	inconclusive	13-Nov-2020	Details
1-[(2,4-dinitrophenyl)azo]-2-naphthol	222-429-4	3468-63-1	Germany	inconclusive	13-Nov-2020	Details
1-[(2-chloro-4-nitrophenyl)azo]-2-naphthol	220-562-2	2814-77-9	Germany	inconclusive	13-Nov-2020	Details

Showing 1 - 25 of 236 results.

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