PBT assessment list

ECHA’s persistence, bioaccumulation and toxicity (PBT) assessment list includes the substances undergoing a PBT/vPvB assessment that have been brought for discussion to ECHA’s PBT Expert Group.

Explanatory note

Inclusion in the list means that an informal hazard assessment for PBT/vPvB properties either is under development or has been completed since February 2013.

For each substance, the table shows the assessing or evaluating Member State (submitter), the outcome from the assessment, and the date of the latest update to the list entry.

Other process details and hazard assessment outcome documents are also available and can be accessed through the ‘Details’ icon.

One possible outcome of such an assessment is that a substance is considered not to have PBT/vPvB properties.

If the outcome is that the substance is considered to have PBT/vPvB properties, confirmation through the formal risk management and decision-making processes is needed before any regulatory action can be taken due to these properties.

The intentions of authorities to submit a dossier to the formal REACH and CLP processes are notified through the Registry of Intentions. All biocidal active substances have to undergo a formal PBT assessment. You can see the status of biocides assessments on the Biocidal Active Substances page.

Disclaimer

The information and views set out in the PBT assessment list and in the hazard assessment outcome documents are those of the evaluating authority and do not necessarily reflect the position or opinion of the other Member States or ECHA. Neither ECHA nor the evaluating authority nor any person acting on either of their behalves may be held liable for the use, which may be made of the information contained therein. Statements made or information contained in the documents are without prejudice to any formal regulatory activities that ECHA or the Member States may initiate at a later stage. PBT assessments and their outcomes are compiled on the basis of information available by the date of the publication of the document.

Last updated 09 March 2023. Database contains 228 unique substances/entries.

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Latest update:

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Date of intention:

Date of hazard assessment:

Showing 151 - 200 of 232 results.

Substance name	EC / List no	CAS no	Authority	Outcome	Latest update
[1,3(or 1,4)-phenylenebis(1-methylethylidene)]bis[tert-butyl] peroxide	246-678-3	25155-25-3	Netherlands	Under development under SEV	04-May-2015	Details
6,6'-di-tert-butyl-4,4'-thiodi-m-cresol	202-525-2	96-69-5	Austria	Under development under SEV	05-Jun-2015	Details
6,6'-di-tert-butyl-4,4'-butylidenedi-m-cresol	201-618-5	85-60-9	France	Under development under SEV	02-Jun-2020	Details
5-sec-butyl-2-(2,4-dimethylcyclohex-3-en-1-yl)-5-methyl-1,3-dioxane [1], 5-sec-butyl-2-(4,6-dimethylcyclohex-3-en-1-yl)-5-methyl-1,3-dioxane [2] covering any of the individual stereoisomers of [1] and [2] or any combination thereof show/hide 1,3-Dioxane, 2-(2,4-dimethyl-3-cyclohexen-1-yl)-5-methyl-5-(1-methylpropyl)- EC / List no: - \| CAS no: 186309-28-4 Reaction mass of 5-sec-butyl-2-(2,4-dimethylcyclohex-3-en-1-yl)-5-methyl-1,3-dioxane and 5-sec-butyl-2-(4,6-dimethylcyclohex-3-en-1-yl)-5-methyl-1,3-dioxane EC / List no: 413-720-9 \| CAS no: - 1,3-Dioxane, 2-[(1R,2R)-2,4-dimethyl-3-cyclohexen-1-yl]-5-methyl-5-(1-methylpropyl)-, cis-rel- EC / List no: - \| CAS no: 343934-04-3 1,3-Dioxane, 2-[(1R,2R)-2,4-dimethyl-3-cyclohexen-1-yl]-5-methyl-5-(1-methylpropyl)-, trans- EC / List no: - \| CAS no: 676367-09-2 1,3-Dioxane, 2-[(1R,2R)-2,4-dimethyl-3-cyclohexen-1-yl]-5-methyl-5-(1-methylpropyl)-, trans-rel- EC / List no: - \| CAS no: 343934-05-4 1,3-Dioxane, 2-[(1R,2S)-2,4-dimethyl-3-cyclohexen-1-yl]-5-methyl-5-(1-methylpropyl)-, cis- EC / List no: - \| CAS no: 676367-04-7 1,3-Dioxane, 2-[(1R,2S)-2,4-dimethyl-3-cyclohexen-1-yl]-5-methyl-5-(1-methylpropyl)-, trans- EC / List no: - \| CAS no: 676367-08-1 1,3-Dioxane, 2-[(1S,2R)-2,4-dimethyl-3-cyclohexen-1-yl]-5-methyl-5-(1-methylpropyl)-, cis- EC / List no: - \| CAS no: 676367-03-6 1,3-Dioxane, 2-[(1S,2R)-2,4-dimethyl-3-cyclohexen-1-yl]-5-methyl-5-(1-methylpropyl)-, trans- EC / List no: - \| CAS no: 676367-07-0 1,3-Dioxane, 2-[(1S,2S)-2,4-dimethyl-3-cyclohexen-1-yl]-5-methyl-5-(1-methylpropyl)-, cis- EC / List no: - \| CAS no: 676367-02-5 1,3-Dioxane, 2-[(1S,2S)-2,4-dimethyl-3-cyclohexen-1-yl]-5-methyl-5-(1-methylpropyl)-, trans- EC / List no: - \| CAS no: 676367-06-9 Reaction mass of 5-[(2R)-butan-2-yl]-2-[(1R,2R)-2,4-dimethylcyclohex-3-en-1-yl]-5-methyl-1,3-dioxane and 5-[(2R)-butan-2-yl]-2-[(1R,6R)-4,6-dimethylcyclohex-3-en-1-yl]-5-methyl-1,3-dioxane and 5-[(2S)-butan-2-yl]-2-[(1R,2R)-2,4-dimethylcyclohex-3-en-1-yl]-5-methyl-1,3-dioxane and 5-[(2S)-butan-2-yl]-2-[(1S,2R)-2,4-dimethylcyclohex-3-en-1-yl]-5-methyl-1,3-dioxane and 5-[(2S)-butan-2-yl]-2-[(1S,6R)-4,6-dimethylcyclohex-3-en-1-yl]-5-methyl-1,3-dioxane EC / List no: 700-927-7 \| CAS no: - 1,3-Dioxane, 2-(2,4-dimethyl-3-cyclohexen-1-yl)-5-methyl-5-(1-methylpropyl)- EC / List no: 601-499-3 \| CAS no: 117933-89-8 5-sec-butyl-2-(2,4-dimethylcyclohex-3-en-1-yl)-5-methyl-1,3-dioxane EC / List no: - \| CAS no: - 5-sec-butyl-2-(4,6-dimethylcyclohex-3-en-1-yl)-5-methyl-1,3-dioxane EC / List no: - \| CAS no: - 1,3-Dioxane, 2-[(1R,2R)-2,4-dimethyl-3-cyclohexen-1-yl]-5-methyl-5-(1-methylpropyl)-, cis- EC / List no: - \| CAS no: 676367-05-8	-	-	Netherlands	vPvB	24-Jan-2019	Details
4-(1,1,3,3-tetramethylbutyl)phenol	205-426-2	140-66-9	ECHA	postponed	10-Mar-2022	Details
4,4'-methylenediphenyl diisocyanate	202-966-0	101-68-8	Estonia	not PBT not vPvB	28-Jan-2019	Details
4,4'-Methylene-bis-(3-chloro-2,6-diethylaniline)	402-130-7	106246-33-7	Netherlands	Under development	18-Feb-2021	Details
4,4'-methylene bis(dibutyldithiocarbamate)	233-593-1	10254-57-6	Germany	Under development	27-Oct-2022	Details
4,4'-[(isopropylidene)bis(p-phenyleneoxy)]diphthalic dianhydride	253-781-7	38103-06-9	Germany	postponed	10-Mar-2022	Details
4,4'-(1,3-phenylene-bis(1-methylethylidene))bis-phenol	428-970-4	13595-25-0	Belgium	postponed	28-Apr-2022	Details
3-Isocyanatomethyl-3,5,5-trimethylcyclohexyl isocyanate homopolymer, isocyanurate type	931-312-3	53880-05-0	ECHA	Under development	27-Mar-2019	Details
3-ethoxy-1,1,1,2,3,4,4,5,5,6,6,6-dodecafluoro-2-(trifluoromethyl)-hexane	435-790-1	297730-93-9	Spain	Under development under SEV	30-Sep-2019	Details
3,7,11-trimethyldodeca-1,6,10-trien-3-ol,mixed isomers	230-597-5	7212-44-4	Austria	not PBT not vPvB	05-Jun-2015	Details
3,7,11,15-tetramethylhexadec-1-en-3-ol	208-008-8	505-32-8	Germany	not PBT not vPvB	08-Dec-2021	Details
3,3,4,4,5,5,6,6,7,7,8,8,8-tridecafluorooctyl methacrylate	218-407-9	2144-53-8	Germany	Under development under SEV	04-May-2016	Details
3,3,4,4,5,5,6,6,7,7,8,8,8-tridecafluorooctyl acrylate	241-527-8	17527-29-6	Germany	Under development under SEV	04-May-2016	Details
3,3'-dimethylbiphenyl-4,4'-diyl diisocyanate	202-112-7	91-97-4	France	not PBT	28-Oct-2021	Details
2-octyldodecan-1-ol	226-242-9	5333-42-6	France	not PBT not vPvB	01-Apr-2015	Details
2-hexyldecan-1-ol	219-370-1	2425-77-6	Netherlands	Under development	01-Apr-2015	Details
2-ethylhexyl diphenyl phosphate	214-987-2	1241-94-7	United Kingdom	not PBT not vPvB	01-Apr-2015	Details
2-ethyl-4-(2,2,3-trimethyl-3-cyclopenten-1-yl)-2-buten-1-ol	248-908-8	28219-61-6	United Kingdom	not PBT not vPvB	01-Apr-2015	Details
2-Ethoxy-3,3,4,4,5-pentafluoro-2,5-bis[(1,2,2,2-tetrafluoro-1-trifluoromethyl)ethyl] tetrahydrofuran	484-410-9	-	Spain	Under development under SEV	27-Mar-2019	Details
2-[methyl[(nonafluorobutyl)sulphonyl]amino]ethyl acrylate	266-733-5	67584-55-8	Germany	not PBT	23-Mar-2020	Details
2-[2-(3-butoxypropyl)-1,1-dioxo-1,2,4-benzothiadiazin-3-yl]-5'-tert-butyl-2-(5,5-dimethyl-2,4-dioxo-1,3-oxazolidin-3-yl)-2'-[(2-ethylhexyl)thio]acetanilide	448-060-0	727678-39-9	Germany	Under development	27-Jan-2022	Details
2-[(4-methoxy-2-nitrophenyl)azo]-N-(2-methoxyphenyl)-3-oxobutyramide	229-419-9	6528-34-3	Italy	Under development under SEV	02-Jun-2020	Details
2-[(4-chloro-2-nitrophenyl)azo]-N-(2-chlorophenyl)-3-oxobutyramide	229-355-1	6486-23-3	Italy	Under development under SEV	02-Jun-2020	Details
2-[(2-methoxy-4-nitrophenyl)azo]-N-(2-methoxyphenyl)-3-oxobutyramide	228-768-4	6358-31-2	Italy	Under development under SEV	02-Jun-2020	Details
2-(4-tert-butylbenzyl)propionaldehyde	201-289-8	80-54-6	Sweden	not PBT not vPvB	13-Jun-2016	Details
2-(2H-benzotriazol-2-yl)-p-cresol	219-470-5	2440-22-4	Germany	Under development	08-Apr-2021	Details
2-(2H-Benzotriazol-2-yl)-6-(1-methyl-1-phenylethyl)-4-(1,1,3,3-tetramethylbutyl)phenol	422-600-5	73936-91-1	Germany	Under development	01-Apr-2015	Details
2-(2H-benzotriazol-2-yl)-4-(tert-butyl)-6-(sec-butyl)phenol	253-037-1	36437-37-3	Germany	vPvB	27-Mar-2019	Details
2-(2H-benzotriazol-2-yl)-4-(1,1,3,3-tetramethylbutyl)phenol	221-573-5	3147-75-9	Germany	Under development	01-Apr-2015	Details
2-(2H-benzotriazol-2-yl)-4,6-ditertpentylphenol	247-384-8	25973-55-1	Germany	PBT vPvB	06-Nov-2020	Details
2-(2H-benzotriazol-2-yl)-4,6-ditertpentylphenol	247-384-8	25973-55-1	Switzerland		11-Aug-2020	Details
2-(2H-benzotriazol-2-yl)-4,6-bis(1-methyl-1-phenylethyl)phenol	274-570-6	70321-86-7	Germany	Under development	01-Apr-2015	Details
2-(1-(3',3'-dimethyl-1'-cyclohexyl)ethoxy)-2-methyl propyl propanoate HELVETOLIDE	415-490-5	141773-73-1	Germany	not PBT not vPvB	20-Dec-2021	Details
2,9-dimethylanthra[2,1,9-def:6,5,10-d'e'f']diisoquinoline-1,3,8,10(2H,9H)-tetrone	226-866-1	5521-31-3	Belgium	Under development	30-Jun-2021	Details
2,6-dichloro-N-phenylaniline	239-349-0	15307-93-4	To Be Defined	postponed	17-Mar-2022	Details
2,6-di-tert-butylphenol	204-884-0	128-39-2	Belgium	not PBT not vPvB	01-Apr-2015	Details
2,5-Furandione, dihydro-, mono-C15-20-alkenyl derivs.	272-221-2	68784-12-3	Norway	not PBT not vPvB	01-Apr-2015	Details
2,5-di-tert-pentylhydroquinone	201-222-2	79-74-3	Italy	Under development under SEV	31-Jan-2020	Details
2,4-di-tert-butylphenol	202-532-0	96-76-4	Belgium	not PBT not vPvB	01-Apr-2015	Details
2,4-di-tert-butyl-6-(5-chlorobenzotriazol-2-yl)phenol	223-383-8	3864-99-1	Germany	vPvB	27-Mar-2019	Details
2,4,6-tris(2,4,6-tribromophenoxy)-1,3,5-triazine SR-245	426-040-2	25713-60-4	Netherlands	Under development	04-May-2015	Details
2,4,6-trichloro-1,3,5-triazine	203-614-9	108-77-0	Poland	not PBT not vPvB	24-Jan-2019	Details
2,4,6-tribromophenol	204-278-6	118-79-6	Norway	postponed	17-Mar-2022	Details
2,4,6-triallyloxy-1,3,5-triazine	202-936-7	101-37-1	France	Under development	01-Apr-2015	Details
2,4,6-tri-tert-butylphenol	211-989-5	732-26-3	Belgium	PBT vPvB	24-Jan-2019	Details
2,2,6,6-tetrakis(tetradecanoyloxymethyl)-4-oxa-heptane-1,7-diyl ditetradecanoate	442-200-4	-	To Be Defined	postponed	10-Mar-2022	Details
2,2'-[(3,3'-dichloro[1,1'-biphenyl]-4,4'-diyl)bis(azo)]bis[N-(4-chloro-2,5-dimethoxyphenyl)-3-oxobutyramide]	226-939-8	5567-15-7	Belgium	not PBT not vPvB	11-Dec-2015	Details

Showing 151 - 200 of 232 results.

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PBT assessment list

PBT assessment list

PBT assessment list

Further information

Last updated 09 March 2023. Database contains 228 unique substances/entries.

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