Previous Testing Proposals

This page provides the list of testing proposal consultations for which the deadline for comments has passed. ECHA addresses all third-party contributions in the dossier evaluation decisions addressed to the registrant.

Further instructions

To see if testing proposals submitted by registrants, and for which ECHA has held a third-party consultation, were subsequently withdrawn, please consult the table below. First, follow the link to the related aggregated registration dossier (if it is already published). There you can review the details of the testing proposed and other information on the substance that is subject to the testing proposal. The admissibility of any testing proposal will be concluded only after the third party consultation. Later during the testing proposal examination process, you may check the same section in the disseminated dossier to see if a testing proposal previously present has been withdrawn. The reasons for withdrawal may be that the registrant has reviewed their assessment or has taken into account the third-party comments provided to ECHA and communicated to them.

Showing 301 - 350 of 2,011 results.

Name	EC Number	CAS Number	Hazard endpoint for which vertebrate testing was proposed	Date of publication to call for available information	Deadline for submitting information
Diundecyl phthalate	222-884-9	3648-20-2	Reproductive toxicity (pre-natal developmental toxicity)	25/11/2021	10/01/2022	Details
Magnesium metaborate	237-235-5	13703-82-7	Reproductive toxicity (pre-natal developmental toxicity)	25/11/2021	10/01/2022	Details
Reaction products of 5,5-dimethylhydantoin and ethylene oxide	701-388-0	-	Reproductive toxicity (pre-natal developmental toxicity)	25/11/2021	10/01/2022	Details
Reaction products of amines, polyethylenepoly-, tetraethylenepentamine fraction and copper sulphate (1:1)	701-400-4	-	Genetic toxicity in vivo	25/11/2021	10/01/2022	Details
Reaction products of amines, polyethylenepoly-, triethylenetetramine fraction and copper sulphate (1:1)	701-399-0	-	"Genetic toxicity in vivo \|\| Note: testing proposed with Reaction products of amines, polyethylenepoly-, tetraethylenepentamine fraction and copper sulphate (1:1) (EC 701-400-4)"	25/11/2021	10/01/2022	Details
Reaction products of diazotised 4,4-diaminodiphenylamine-2-sulfonic acid, subsequently coupled with 6-amino-4-hydroxynaphthalene-2-sulfonic acid, further diazotised and coupled with metaphenylendiamine, sodium salts	939-382-7	-	Genetic toxicity in vivo	25/11/2021	10/01/2022	Details
Reaction products of tetrazotized 5-amino-2-[(E)-2-(4-amino-2-sulfophenyl)ethenyl]benzenesulfonic acid with 6-amino-4-hydroxynaphthalene-2-sulfonic acid and 4-amino-5-hydroxynaphthalene-2,7-disulfonic acid in 2-[bis(2-hydroxyethyl)amino]ethanol	916-899-6	-	Long-term toxicity to fish	25/11/2021	10/01/2022	Details
Sulphamidic acid	226-218-8	5329-14-6	Reproductive toxicity (pre-natal developmental toxicity)	25/11/2021	10/01/2022	Details
SUMILIZER GP	442-450-4	-	Long-term toxicity to fish	25/11/2021	10/01/2022	Details
Tetraammineplatinum dichloride	237-706-5	13933-32-9	Genetic toxicity in vivo	25/11/2021	10/01/2022	Details
Vinylene carbonate	212-825-5	872-36-6	Reproductive toxicity (pre-natal developmental toxicity)	25/11/2021	10/01/2022	Details
Lithium bis(fluorosulfonyl)imide	686-526-7	171611-11-3	Sub-chronic toxicity (90-day): oral Reproductive toxicity (extended one-generation reproductive toxicity study) Reproductive toxicity (pre-natal developmental toxicity)	21/10/2021 21/10/2021 21/10/2021	07/12/2021 07/12/2021 07/12/2021	Details
Ditolyl ether	248-948-6	28299-41-4	Reproductive toxicity (extended one-generation reproductive toxicity study) Reproductive toxicity (pre-natal developmental toxicity)	21/10/2021 21/10/2021	07/12/2021 07/12/2021	Details
2,7-naphthalenedisulfonic acid, 4-amino-5-hydroxy-, diazotized, coupled with diazotized 2-amino-4,6-dinitrophenol, diazotized 4-nitrobenzenamine and resorcinol, sodium salts	232-380-0	8011-86-7	Genetic toxicity in vivo	21/10/2021	07/12/2021	Details
2-(2-(2-ethoxyethoxy)ethoxy)ethanol	203-978-9	112-50-5	Reproductive toxicity (extended one-generation reproductive toxicity study) \|\| Note: testing proposed with 2-(2-(2-methoxyethoxy)ethoxy)ethanol (EC 203-962-1)	21/10/2021	07/12/2021	Details
3,6,9,12-tetraoxotridecanol	245-883-5	23783-42-8	Reproductive toxicity (extended one-generation reproductive toxicity study) \|\| Note: testing proposed with 2-(2-(2-methoxyethoxy)ethoxy)ethanol (EC 203-962-1)	21/10/2021	07/12/2021	Details
Carboxylic acids, di-, C4-6	271-678-5	68603-87-2	Reproductive toxicity (extended one-generation reproductive toxicity study) \|\| Note: testing proposed with adipic acid (EC 204-673-3)	21/10/2021	07/12/2021	Details
Decanal	203-957-4	112-31-2	Reproductive toxicity (pre-natal developmental toxicity)	21/10/2021	07/12/2021	Details
Disodium [2,4-dihydro-4-[(2-hydroxy-5-nitrophenyl)azo]-5-methyl-2-phenyl-3H-pyrazol-3-onato(2-)][3-hydroxy-4-[(2-hydroxy-1-naphthyl)azo]-7-nitronaphthalene-1-sulphonato(3-)]chromate(2-)	274-490-1	70236-60-1	Genetic toxicity in vivo	21/10/2021	07/12/2021	Details
n-methyl-n-[c18-(unsaturated)alkanoyl]glycine	701-177-3	-	Reproductive toxicity (extended one-generation reproductive toxicity study)	21/10/2021	07/12/2021	Details
N-Phenyl-diethanolamine, reaction products with formaldehyde	942-131-4	-	Reproductive toxicity (pre-natal developmental toxicity)	21/10/2021	07/12/2021	Details
Polysulfides, bis[3-(triethoxysilyl)propyl]	915-673-4	-	Sub-chronic toxicity (90-day): oral	21/10/2021	07/12/2021	Details
Propanamide, 2-hydroxy-N,N-dimethyl-	609-066-0	35123-06-9	Reproductive toxicity (extended one-generation reproductive toxicity study)	21/10/2021	07/12/2021	Details
Fatty acids, C12-14 (even numbered), methyl ester	629-776-4	308065-15-8	Sub-chronic toxicity (90-day): oral Reproductive toxicity (extended one-generation reproductive toxicity study) Reproductive toxicity (pre-natal developmental toxicity)	30/09/2021 30/09/2021 30/09/2021	15/11/2021 15/11/2021 15/11/2021	Details
n4,n4'-hexane-1,6-diylbis[n-butyl-6-chloro-n,n'-bis(2,2,6,6-tetramethylpiperidin-4-yl)-1,3,5-triazine-2,4-diamine]	835-183-3	83420-16-0	Bioaccumulation aquatic / sediment Sub-chronic toxicity (90-day): oral Reproductive toxicity (pre-natal developmental toxicity)	30/09/2021 30/09/2021 30/09/2021	15/11/2021 15/11/2021 15/11/2021	Details
Tetrakis(phenylmethyl)thioperoxydi(carbothioamide)	404-310-0	10591-85-2	Long-term toxicity to fish Sub-chronic toxicity (90-day): oral Reproductive toxicity (pre-natal developmental toxicity)	30/09/2021 30/09/2021 30/09/2021	15/11/2021 15/11/2021 15/11/2021	Details
3-(trimethoxysilyl)propyl isocyanate	239-415-9	15396-00-6	Genetic toxicity in vivo Reproductive toxicity (extended one-generation reproductive toxicity study) \|\| Note: it is proposed to use the information from an ongoing study with 3-(trimethoxysilyl)propylamine (EC 237-511-5)	30/09/2021 30/09/2021	15/11/2021 15/11/2021	Details
Ethylene	200-815-3	74-85-1	Reproductive toxicity (extended one-generation reproductive toxicity study) Reproductive toxicity (pre-natal developmental toxicity)	30/09/2021 30/09/2021	15/11/2021 15/11/2021	Details
Saccharomyces cerevisiae, lysate	305-230-8	94350-12-6	Sub-chronic toxicity (90-day): oral Reproductive toxicity (pre-natal developmental toxicity)	30/09/2021 30/09/2021	15/11/2021 15/11/2021	Details
1,1'-(methylenedi-p-phenylene)bismaleimide	237-163-4	13676-54-5	Reproductive toxicity (pre-natal developmental toxicity)	30/09/2021	15/11/2021	Details
3-methoxy-3-methylbutan-1-ol	260-252-4	56539-66-3	Reproductive toxicity (extended one-generation reproductive toxicity study)	30/09/2021	15/11/2021	Details
A mixture of: esters of C14-C15 branched alcohols with 3,5-di-t-butyl-4-hydroxyphenyl propionic acid; C15 branched and linear alkyl 3,5-bis(1,1-dimethylethyl)-4-hydroxybenzenepropanoate; C13 branched and linear alkyl 3,5-bis(1,1-dimethylethyl)-4-hydroxybenzenepropanoate	413-750-2	-	Reproductive toxicity (pre-natal developmental toxicity)	30/09/2021	15/11/2021	Details
benzenesulfonic acid, 4-c10-13-alkyl derivs.-, salts with amines, c16-c18 (even numbered) alkyl	953-378-2	-	Long-term toxicity to fish	30/09/2021	15/11/2021	Details
BICYCLO[3.1.1]HEPT-2-ENE,2,6,6-TRIMETHYL-,POLYMER WITH 6,6-DIMETHYL-2-METHYLENEBICYCLO[3.1.1]HEPTANE	608-613-0	-	Reproductive toxicity (pre-natal developmental toxicity)	30/09/2021	15/11/2021	Details
Dodecanoic acid, 2,2-dimethyl-3-oxopropyl ester	468-880-2	102985-93-3	Long-term toxicity to fish	30/09/2021	15/11/2021	Details
Reaction product of 4,4'-methylenediphenyl diisocyanate (MDI) (101-68-8), Octylamine (111-86-4) and Cyclohexylamine (108-91-8)	926-119-6	-	Long-term toxicity to fish \|\| Note: testing proposed with Reaction mass of 4,4'-methylenediphenyl diisocyanate and Amines, soya alkyl (EC 905-837-3) and Reaction product of 4,4'-methylenediphenyl diisocyanate (MDI) (CAS: 101-68-8), Octylamine (111-86-4) and Hexamethylenediamine (124-09-4) (EC no 924-670-7)	30/09/2021	15/11/2021	Details
Sodium 2,4,5-trichlorobenzenesulphonate	258-548-3	53423-65-7	Genetic toxicity in vivo	30/09/2021	15/11/2021	Details
Alkane 6	438-390-3	-	Sub-chronic toxicity (90-day): oral \|\| Note: testing proposed with 1-Dodecene, dimer, hydrogenated (EC 604-768-3) and 1-Decene, tetramer, mixed with 1-decene trimer, hydrogenated (EC 614-695-9) Reproductive toxicity (extended one-generation reproductive toxicity study \|\| Note: testing proposed with Dec-1-ene, homopolymer, hydrogenated Dec-1-ene, oligomers, hydrogenated (EC 500-183-1), 1-decene, dimer (EC 917-709-4) and 1-Decene, tetramer, mixed with 1-decene trimer, hydrogenated (EC 614-695-9) Reproductive toxicity (pre-natal developmental toxicity) \|\| Note: testing proposed with 1-Dodecene, Dimer (EC 814-509-8), 1-Decene, tetramer, mixed with 1-decene trimer, hydrogenated (EC 614-695-9) and Dec-1-ene, homopolymer, hydrogenated Dec-1-ene, oligomers, hydrogenated (EC 500-183-1)	26/08/2021 26/08/2021 26/08/2021	11/10/2021 11/10/2021 11/10/2021	Details
Branched hexatriacontane	417-070-7	-	Sub-chronic toxicity (90-day): oral \|\| Note: testing proposed with 1-Dodecene, dimer, hydrogenated (EC 604-768-3) and 1-Decene, tetramer, mixed with 1-decene trimer, hydrogenated (EC 614-695-9) Reproductive toxicity (extended one-generation reproductive toxicity study) \|\| Note: testing proposed with Dec-1-ene, homopolymer, hydrogenated Dec-1-ene, oligomers, hydrogenated (EC 500-183-1), 1-decene, dimer (EC 917-709-4), 1-Decene, tetramer, mixed with 1-decene trimer, hydrogenated (EC 614-695-9) Reproductive toxicity (pre-natal developmental toxicity) \|\| Note: testing proposed with 1-Decene, tetramer, mixed with 1-decene trimer, hydrogenated (EC 614-695-9), 1-Dodecene, Dimer (EC 814-509-8 ), Dec-1-ene, homopolymer, hydrogenated Dec-1-ene, oligomers, hydrogenated (EC 500-183-1)	26/08/2021 26/08/2021 26/08/2021	11/10/2021 11/10/2021 11/10/2021	Details
N,N-dimethyl-N'-(2,2,6,6-tetramethylpiperidin-4-yl)propane-1,3-diamine	278-817-9	78014-16-1	Sub-chronic toxicity (90-day): oral Genetic toxicity in vivo Reproductive toxicity (pre-natal developmental toxicity)	26/08/2021 26/08/2021 26/08/2021	11/10/2021 11/10/2021 11/10/2021	Details
(1-methylethylidene)di-4,1-phenylenetetraphenyl diphosphate	425-220-8	5945-33-5	Reproductive toxicity (extended one-generation reproductive toxicity study) Reproductive toxicity (pre-natal developmental toxicity)	26/08/2021 26/08/2021	11/10/2021 11/10/2021	Details
3-chloropropyltrimethoxysilane	219-787-9	2530-87-2	Reproductive toxicity (extended one-generation reproductive toxicity study) Reproductive toxicity (pre-natal developmental toxicity)	26/08/2021 26/08/2021	11/10/2021 11/10/2021	Details
6,8-Dioxabicyclo[3.2.1]octan-4-one, (1S,5R) (Cyrene)	807-130-4	53716-82-8	Sub-chronic toxicity (90-day): oral Reproductive toxicity (pre-natal developmental toxicity)	26/08/2021 26/08/2021	11/10/2021 11/10/2021	Details
N-(2-ethylhexyl)isononan-1-amide	810-288-7	1700656-13-8	Sub-chronic toxicity (90-day): oral Reproductive toxicity (pre-natal developmental toxicity)	26/08/2021 26/08/2021	11/10/2021 11/10/2021	Details
Peracetic acid	201-186-8	79-21-0	Reproductive toxicity (extended one-generation reproductive toxicity study) Reproductive toxicity (pre-natal developmental toxicity)	26/08/2021 26/08/2021	11/10/2021 11/10/2021	Details
Propylidynetrimethanol, ethoxylated, esters with acrylic acid, reaction products with diethylamine	500-425-6	159034-91-0	Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral	26/08/2021 26/08/2021	11/10/2021 11/10/2021	Details
1-Dodecanamine, reaction products with 1,1'-methylenebis[4-isocyanatobenzene] and 1-octanamine	812-490-0	1312943-21-7	Long-term toxicity to fish \|\| Note: testing proposed with Reaction mass of 4,4'-methylenediphenyl diisocyanate and Amines, soya alkyl (EC no. 905-837-3) and Reaction product of 4,4'-methylenediphenyl diisocyanate (MDI) (Octylamine and Hexamethylenediamine (EC no. 924-670-7)	26/08/2021	11/10/2021	Details
1-Octadecanamine, reaction products with 1,1'-methylenebis[4-isocyanatobenzene] and 1-octanamine	812-491-6	1312943-23-9	Long-term toxicity to fish \|\| Note: testing proposed with Reaction mass of 4,4'-methylenediphenyl diisocyanate and Amines, soya alkyl (EC no. 905-837-3) and Reaction product of 4,4'-methylenediphenyl diisocyanate (MDI) , Octylamine) and Hexamethylenediamine (EC no. 924-670-7)	26/08/2021	11/10/2021	Details
2,5-Furandione, dihydro-, mono-C15-20-alkenyl derivs.	272-221-2	68784-12-3	Reproductive toxicity (pre-natal developmental toxicity)	26/08/2021	11/10/2021	Details
2,6-dimethyloct-7-en-2-ol	242-362-4	18479-58-8	Reproductive toxicity (pre-natal developmental toxicity)	26/08/2021	11/10/2021	Details

Showing 301 - 350 of 2,011 results.

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