Previous Testing Proposals

This page provides the list of testing proposal consultations for which the deadline for comments has passed. ECHA addresses all third-party contributions in the dossier evaluation decisions addressed to the registrant.

Further instructions

To see if testing proposals submitted by registrants, and for which ECHA has held a third-party consultation, were subsequently withdrawn, please consult the table below. First, follow the link to the related aggregated registration dossier (if it is already published). There you can review the details of the testing proposed and other information on the substance that is subject to the testing proposal. The admissibility of any testing proposal will be concluded only after the third party consultation. Later during the testing proposal examination process, you may check the same section in the disseminated dossier to see if a testing proposal previously present has been withdrawn. The reasons for withdrawal may be that the registrant has reviewed their assessment or has taken into account the third-party comments provided to ECHA and communicated to them.

Showing 851 - 900 of 2,011 results.

Name	EC Number	CAS Number	Hazard endpoint for which vertebrate testing was proposed	Date of publication to call for available information	Deadline for submitting information
2,3-epoxypropyl neodecanoate	247-979-2	26761-45-5	Reproductive toxicity (extended one-generation reproductive toxicity study)	23/04/2018	07/06/2018	Details
2,5-Furandione, dihydro-, mono-C15-20-alkenyl derivs.	272-221-2	68784-12-3	Reproductive toxicity (extended one-generation reproductive toxicity study)	23/04/2018	07/06/2018	Details
6,6'-di-tert-butyl-2,2'-methylenedi-p-cresol	204-327-1	119-47-1	Reproductive toxicity (extended one-generation reproductive toxicity study)	23/04/2018	07/06/2018	Details
Alcohols, C18-22, distn. residues	641-136-6	1160164-88-4	Reproductive toxicity (extended one-generation reproductive toxicity study)	23/04/2018	07/06/2018	Details
Benzoic acid, 2-hydroxy-, mono-C14-18-alkyl derivs., calcium salts (2:1)	931-276-9	-	Reproductive toxicity (extended one-generation reproductive toxicity study)	23/04/2018	07/06/2018	Details
Decahydronaphthalene	202-046-9	91-17-8	Reproductive toxicity (extended one-generation reproductive toxicity study)	23/04/2018	07/06/2018	Details
Diammonium hexachloroplatinate	240-973-0	16919-58-7	Genetic toxicity in vivo \|\| Note: Testing proposal is based on concern identified by the registrant.	23/04/2018	07/06/2018	Details
Dodecamethylcyclohexasiloxane	208-762-8	540-97-6	Reproductive toxicity (extended one-generation reproductive toxicity study	23/04/2018	07/06/2018	Details
Hexadecyldimethylamine	695-101-5	1275611-65-8	Reproductive toxicity (pre-natal developmental toxicity)	23/04/2018	07/06/2018	Details
Magnesium, bis(2-hydroxybenzoato-O1,O2)-, ar,ar'-di-C14-18alkyl derivs	931-371-5	-	Reproductive toxicity (extended one-generation reproductive toxicity study)	23/04/2018	07/06/2018	Details
Octene, hydroformylation products, high-boiling	271-237-7	68526-89-6	Reproductive toxicity (extended one-generation reproductive toxicity study)	23/04/2018	07/06/2018	Details
Potassium cyanate	209-676-3	590-28-3	Reproductive toxicity (extended one-generation reproductive toxicity study)	23/04/2018	07/06/2018	Details
Reaction products of 1H-Imidazole-1-ethanol, 4,5-dihydro-, 2-(C11-17 and C17 unsatd. alkyl) derivs. and sodium hydroxide and 2-propenoic acid	946-533-0	-	Reproductive toxicity (pre-natal developmental toxicity) \|\| Note: testing proposed with Reaction products of 1H-Imidazole-1-ethanol, 4,5-dihydro-, 2-(C7-C17 odd-numbered, C17-unsatd. alkyl) derivs. and sodium hydroxide and chloroacetic acid (EC 931-291-0)	23/04/2018	07/06/2018	Details
Sulphamidic acid	226-218-8	5329-14-6	Reproductive toxicity (extended one-generation reproductive toxicity study) \|\| Note: testing proposed with ammonium sulphamate (pH consideration)	23/04/2018	07/06/2018	Details
Tetrahydrothiophene 1,1-dioxide	204-783-1	126-33-0	Reproductive toxicity (extended one-generation reproductive toxicity study) / Testing proposal is based on concern identified by the registrant.	23/04/2018	07/06/2018	Details
3,6-bis(4-chlorophenyl)-1H,2H,4H,5H-pyrrolo[3,4-c]pyrrole-1,4-dione	401-540-3	-	Sub-chronic toxicity (90-day): oral Reproductive toxicity (extended one-generation reproductive toxicity study) Reproductive toxicity (pre-natal developmental toxicity)	26/03/2018 26/03/2018 26/03/2018	11/05/2018 11/05/2018 11/05/2018	Details
2,4,4-trimethylpentene	246-690-9	25167-70-8	Sub-chronic toxicity (90-day): oral Reproductive toxicity (pre-natal developmental toxicity) \|\| Note: There are two testing proposals for this endpoint.	26/03/2018 26/03/2018	11/05/2018 11/05/2018	Details
2-methylpentane-2,4-diol	203-489-0	107-41-5	Reproductive toxicity (extended one-generation reproductive toxicity study) Reproductive toxicity (pre-natal developmental toxicity)	26/03/2018 26/03/2018	11/05/2018 11/05/2018	Details
4,4'-methylenebis[2,6-diethylaniline]	237-185-4	13680-35-8	Long-term toxicity to fish Genetic toxicity in vivo	26/03/2018 26/03/2018	11/05/2018 11/05/2018	Details
alkyl amine and alkylbenzenesulphonate	-	-	Sub-chronic toxicity (90-day): oral Reproductive toxicity (pre-natal developmental toxicity)	26/03/2018 26/03/2018	11/05/2018 11/05/2018	Details
Tris(2-butoxyethyl) phosphate	201-122-9	78-51-3	Reproductive toxicity (extended one-generation reproductive toxicity study) Reproductive toxicity (pre-natal developmental toxicity)	26/03/2018 26/03/2018	11/05/2018 11/05/2018	Details
1,1'-isopropylidenebis(p-phenyleneoxy)dipropan-2-ol	204-137-9	116-37-0	Reproductive toxicity (extended one-generation reproductive toxicity study)	26/03/2018	11/05/2018	Details
1,2,3,4-tetrahydronaphthalene	204-340-2	119-64-2	Reproductive toxicity (extended one-generation reproductive toxicity study)	26/03/2018	11/05/2018	Details
1-Hexanol, 2-ethyl-, manuf. of, by-products from, distn. residues	271-832-1	68609-68-7	Reproductive toxicity (extended one-generation reproductive toxicity study)	26/03/2018	11/05/2018	Details
2,2'-[oxybis(methylene)]bis[2-ethylpropane-1,3-diol]	245-509-0	23235-61-2	Reproductive toxicity (extended one-generation reproductive toxicity study)	26/03/2018	11/05/2018	Details
2-chloropropane	200-858-8	75-29-6	Reproductive toxicity (extended one-generation reproductive toxicity study)	26/03/2018	11/05/2018	Details
3-C12-18-(even numbered)-alkylamido-N,N-dimethylpropan-1-amino oxide	939-581-9	-	Reproductive toxicity (pre-natal developmental toxicity)	26/03/2018	11/05/2018	Details
6'-(dibutylamino)-3'-methyl-2'-(phenylamino)spiro[isobenzofuran-1(3H),9-(9H)-xanthen]-3-one	403-830-5	89331-94-2	Sub-chronic toxicity (90-day): oral	26/03/2018	11/05/2018	Details
Barium chloride	233-788-1	10361-37-2	Reproductive toxicity (extended one-generation reproductive toxicity study)	26/03/2018	11/05/2018	Details
Bis(2-(2-butoxyethoxy)ethoxy)methane	205-598-9	143-29-3	Reproductive toxicity (extended one-generation reproductive toxicity study)	26/03/2018	11/05/2018	Details
Dimethoxymethane	203-714-2	109-87-5	Reproductive toxicity (extended one-generation reproductive toxicity study)	26/03/2018	11/05/2018	Details
Dipotassium hexachloroplatinate	240-979-3	16921-30-5	Genetic toxicity in vivo \|\| Note: Testing proposal is based on concern identified by the registrant.	26/03/2018	11/05/2018	Details
Hexachloroplatinic acid	241-010-7	16941-12-1	Genetic toxicity in vivo \|\| Note: testing proposed with Diammonium hexachloroplatinate (EC 241-010-7). Testing proposal is based on concern identified by the registrant.	26/03/2018	11/05/2018	Details
inorganic phosphorus salt	428-310-5	-	Reproductive toxicity (extended one-generation reproductive toxicity study)	26/03/2018	11/05/2018	Details
Phenol, isopropylated, phosphate (3:1)	273-066-3	68937-41-7	Reproductive toxicity (extended one-generation reproductive toxicity study)	26/03/2018	11/05/2018	Details
Slags, ferromanganese-manufg.	273-728-1	69012-28-8	Reproductive toxicity (pre-natal developmental toxicity)	26/03/2018	11/05/2018	Details
C16-(branched), C20-(branched) and C24-(branched)-alkanes	700-992-1	-	Sub-chronic toxicity (90-day): oral Reproductive toxicity (extended one-generation reproductive toxicity study) Reproductive toxicity (pre-natal developmental toxicity)	28/02/2018 28/02/2018 28/02/2018	16/04/2018 16/04/2018 16/04/2018	Details
4-tert-butylpyrocatechol	202-653-9	98-29-3	Genetic toxicity in vivo \|\| Note: Testing proposal is based on concern identified by the registrant. Reproductive toxicity (extended one-generation reproductive toxicity study)	28/02/2018 28/02/2018	16/04/2018 16/04/2018	Details
ethyl methyl carbonate	433-480-9	-	Sub-chronic toxicity (90-day): oral \|\| Note: testing proposed with an analogue substance. Reproductive toxicity (pre-natal developmental toxicity) \|\| Note: testing proposed with an analogue substance.	28/02/2018 28/02/2018	16/04/2018 16/04/2018	Details
Fatty acids, C18-unsatd., dimers, oligomeric reaction products with tall-oil fatty acids and triethylenetetramine	500-191-5	-	Sub-chronic toxicity (90-day): oral Reproductive toxicity (pre-natal developmental toxicity)	28/02/2018 28/02/2018	16/04/2018 16/04/2018	Details
Fatty acids, C18-unsatd., dimers, polymers with oleic acid and triethylenetetramine	701-120-2	-	Sub-chronic toxicity (90-day): oral \|\| Note: testing proposed with Fatty acids, C18-unsatd., dimers, oligomeric reaction products with tall-oil fatty acids and triethylenetetramine Reproductive toxicity (pre-natal developmental toxicity) \|\| Note: testing proposed with Fatty acids, C18-unsatd., dimers, oligomeric reaction products with tall-oil fatty acids and triethylenetetramine	28/02/2018 28/02/2018	16/04/2018 16/04/2018	Details
Fatty acids, C18-unsatd., dimers, reaction products with polyethylenepolyamines	614-452-7	68410-23-1	Sub-chronic toxicity (90-day): oral \|\| Note: testing proposed with Fatty acids, C18-unsatd., dimers, oligomeric reaction products with tall-oil fatty acids and triethylenetetramine Reproductive toxicity (pre-natal developmental toxicity) \|\| Note: testing proposed with Fatty acids, C18-unsatd., dimers, oligomeric reaction products with tall-oil fatty acids and triethylenetetramine	28/02/2018 28/02/2018	16/04/2018 16/04/2018	Details
Polysulfides, bis[3-(triethoxysilyl)propyl]	915-673-4	-	Reproductive toxicity (extended one-generation reproductive toxicity study) Reproductive toxicity (pre-natal developmental toxicity)	28/02/2018 28/02/2018	16/04/2018 16/04/2018	Details
Triethoxy(2,4,4-trimethylpentyl)silane	252-558-1	35435-21-3	Long-term toxicity to fish \|\| Note: Testing on fish needs to be considered in relation to the testing proposal for long-term toxicity to aquatic invertebrates. Reproductive toxicity (extended one-generation reproductive toxicity study) \|\| Note: testing proposed with triethoxyoctylsilane (CAS 2943-75-1)	28/02/2018 28/02/2018	16/04/2018 16/04/2018	Details
2-Butyne-1,4-diol, polymer with 2-(chloromethyl)oxirane, brominated, dehydrochlorinated, methoxylateddehydrochlorinated, methoxylated	614-503-3	68441-62-3	Reproductive toxicity (extended one-generation reproductive toxicity study)	28/02/2018	16/04/2018	Details
Alkenes, C11-12, hydroformylation products, distn. Residues	292-427-6	90622-27-8	Reproductive toxicity (extended one-generation reproductive toxicity study)	28/02/2018	16/04/2018	Details
Aluminium oxide	215-691-6	1344-28-1	Genetic toxicity in vivo \|\| Note: Testing proposal for two in vivo studies is based on concern identified by the registrant. Testing proposed with Aluminium oxide nanoscale material.	28/02/2018	16/04/2018	Details
Bis(4-chlorophenyl) sulphone	201-247-9	80-07-9	Reproductive toxicity (extended one-generation reproductive toxicity study)	28/02/2018	16/04/2018	Details
Calcium cyanamide	205-861-8	156-62-7	Reproductive toxicity (extended one-generation reproductive toxicity study)	28/02/2018	16/04/2018	Details
Citral	226-394-6	5392-40-5	Reproductive toxicity (extended one-generation reproductive toxicity study)	28/02/2018	16/04/2018	Details

Showing 851 - 900 of 2,011 results.

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