Registered substances

Data platform availability banner - registered substances

The new ECHA CHEM database has been released by ECHA. At first this system will contain only substances and data from REACH registration dossiers. For new and updated REACH registration data please check ECHA CHEM. See for more information on the transition to ECHA CHEM.  More

Please be aware that REACH registration data here on the current Dissemination Platform is no longer maintained; it remains frozen as of 19th May 2023.



REACH - Registration, Evaluation, Authorisation and Restriction of Chemicals Regulation

Registered Substances Factsheets

Substances which have been registered and can be placed on the EEA market by those companies with a valid registration

No results were found
465-070-0 - Active Intermediate Joint Intermediate use only 29-05-2019 View substance registered dossier
465-070-0 - Active NONS Individual Tonnage data confidential 10-11-2008 View substance registered dossier
452-330-3 - Active Intermediate Joint Intermediate use only 16-12-2020 View substance registered dossier
401-600-9 - Active NONS Individual Tonnage data confidential 10-11-2008 View substance registered dossier
2-(2-(4-(dibenzo[b,f][1,4]thiazepin-11-yl)piperazin-1-yl)ethoxy)ethan-1-ol fumarate
924-097-2 - Active Intermediate Individual Intermediate use only 14-05-2018 View substance registered dossier
2-(2-(4-benzoyl-phenoxy)ethoxy)ethyl 2-methylprop-2-enoate
943-359-7 - Active Full Joint ≥ 10 to < 100 tonnes 11-10-2018 View substance registered dossier
2-(2-bromo-4,5-dimethoxyphenyl)ethan-1-amine hydrobromide
920-619-8 - Active Intermediate Joint Intermediate use only 05-06-2018 View substance registered dossier
2-(2-Ethoxyphenoxy)ethanaminium methanesulfonate
689-022-5 - Active Intermediate Individual Intermediate use only 16-09-2011 View substance registered dossier
2-(2-methoxyphenoxy)ethyl 4-toluenesulfonate
403-930-9 - Cease Manufacture NONS Individual Cease manufacture 07-09-2010 View substance registered dossier
446-650-2 - Active Full Individual ≥ 100 to < 1 000 tonnes 20-05-2016 View substance registered dossier
No results were found
Registrant/Supplier Address Country Registration Status Name EC / List no. CAS no. Last update year Details
MSD International GmbH (Ballydine Branch) Ballydine - Kilsheelan 0 Clonmel Ireland Ireland Active 2-(1-amino-1-methylethyl)-N-(4-fluorobenzyl)-5-hydroxy-1-methyl-6-oxo-1,6-dihydropyrimidine-4-carboxamide 465-070-0 - 2011; 2012; 2018; 2019 View substance registered dossier
F.I.S. Fabbrica Italiana Sintetici S.p.a. Viale Milano, 26 36075 Montecchio Maggiore (VI) Veneto Italy Italy Active 2-(1-amino-1-methylethyl)-N-(4-fluorobenzyl)-5-hydroxy-1-methyl-6-oxo-1,6-dihydropyrimidine-4-carboxamide 465-070-0 - - View substance registered dossier
Syngenta Hellas Single Member S.A.C.I. Anthousas Avenue 153 49 Anthousa - Attiki Greece Greece Active 2-(2,6-diethyl-4-methyl-phenyl)propanediamide 452-330-3 - - View substance registered dossier
Syngenta Ltd Jealott’s Hill International Research Centre RG42 6EY Bracknell Berkshire United Kingdom United Kingdom No longer Valid 2-(2,6-diethyl-4-methyl-phenyl)propanediamide 452-330-3 - 2021 View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant UK competent national authority. - - Active 2-(2-(2,4-dioctyloxyphenyl)vinyl)quinoline 401-600-9 - - View substance registered dossier
N.V. Ajinomoto OmniChem S.A. Cooppallaan 91 9230 Wetteren Oost-Vlaanderen Belgium Belgium Active 2-(2-(4-(dibenzo[b,f][1,4]thiazepin-11-yl)piperazin-1-yl)ethoxy)ethan-1-ol fumarate 924-097-2 - - View substance registered dossier
[Confidential] - - - 2-(2-(4-benzoyl-phenoxy)ethoxy)ethyl 2-methylprop-2-enoate 943-359-7 - - View substance registered dossier
CU Chemie Uetikon GmbH Raiffeisenstrasse 4 77933 Lahr Baden-Württemberg Germany Germany Active 2-(2-bromo-4,5-dimethoxyphenyl)ethan-1-amine hydrobromide 920-619-8 - - View substance registered dossier
Synthon, s.r.o. Brněnská 32 678 01 Blansko Czech Republic Czech Republic Active 2-(2-Ethoxyphenoxy)ethanaminium methanesulfonate 689-022-5 - - View substance registered dossier
Roche Diagnostics GmbH Sandhoferstrasse 116 68305 Mannheim Germany Germany Cease Manufacture 2-(2-methoxyphenoxy)ethyl 4-toluenesulfonate 403-930-9 - 2019 View substance registered dossier
UCB Pharma S.A.(Belgium) Allée de la recherche, 60 1070 Brussels Belgium Belgium Active 2-(2-oxopyrrolidin-1-yl)butyramide 446-650-2 - 2013; 2016 View substance registered dossier

In this table, you will find all public data submitted to ECHA in REACH registration dossiers by substance manufacturers, importers, or their representatives, as laid out by the REACH Regulation (see Understanding REACH regulation).

ECHA makes available this information as REACH registered substance factsheets, which contain the full set of non-confidential information from related registration dossiers for a substance. Depending on the number of registrations that have been made for a substance, one factsheet can thus represent data from anything between hundreds of registration dossiers in a joint submission, to data from just one registration dossier.

As noted in the Legal Notice of the ECHA website, ECHA does not give any guarantees or warranties regarding the quality and correctness of the published information. The information in the portal is published ‘as provided’ by industry, and its accuracy has not been verified by ECHA. ECHA is also not in a position to intervene with, edit or correct the published data; this can only be done by the registrant responsible for its submission. Please also note that the information may be protected and its use may require prior permission from its owner (see the ECHA website Legal Notice more details).

In the portal results table are presented:

  • Public substance identity – the best available non-confidential substance name, EC, and CAS numbers.
  • Registration status – indicating the calculated registration status for the whole factsheet: Active – is being manufactured or imported to the EEA by one or more registrants; Cease Manufacture - is no longer being manufactured or imported above 1 tone per calendar year. All registrants of the substance have reported a cease of manufacture or import; or No longer valid - no longer considered registered under REACH and not currently allowed to be manufactured or imported to the EEA, until the substance is registered again.
  • Registration type – indicating whether a given factsheet contains data from a REACH full registration, REACH intermediate registration, or only a limited set of data inherited from a NONS notification.
  • Submission type – indicating whether the data in a given factsheet was submitted jointly or individually.
  • Total tonnage band – calculated per factsheet from all contributing registrations, based on the estimated quantity of the substance placed on the market. Data is excluded from dossiers where the tonnage is claimed confidential, from Intermediate registration dossiers, and from NONs which have not been updated.
  • Last updated – indicating the date on which this registered substance factsheet was last modified with new or updated data, based on an industry submission.
  • Link to the full factsheet.

A subset of the key chemical properties (physico-chemical, environmental fate, ecotoxicological and toxicological data) of registered substances can be searched and accessed via the OECD eChemPortal.