Registered substances

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The new ECHA CHEM database has been released by ECHA. At first this system will contain only substances and data from REACH registration dossiers. For new and updated REACH registration data please check ECHA CHEM. See for more information on the transition to ECHA CHEM.  More

Please be aware that REACH registration data here on the current Dissemination Platform is no longer maintained; it remains frozen as of 19th May 2023.



REACH - Registration, Evaluation, Authorisation and Restriction of Chemicals Regulation

Registered Substances Factsheets

Substances which have been registered and can be placed on the EEA market by those companies with a valid registration

No results were found
(6S,7S)-7-Amino-3-(methoxymethyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
435-680-1 - Cease Manufacture Full Individual Cease manufacture 17-05-2018 View substance registered dossier
(7-Hydroxy-2-naphthyl)-trimethylammonium methyl sulphate
807-380-4 377734-55-9 No longer Valid Full Joint No longer valid 26-03-2018 View substance registered dossier
617-813-7 861960-34-1 Active Full Joint ≥ 1 to < 10 tonnes 11-05-2018 View substance registered dossier
461-670-1 - Active Full Individual ≥ 1 to < 10 tonnes 08-06-2010 View substance registered dossier
(7R)-4-(5-Chloro-1,3-benzoxazol-2-yl)-7-methyl-1,4-diazepan-1-ium chloride
690-742-7 1266664-66-7 Active Full Joint ≥ 10 to < 100 tonnes 20-05-2020 View substance registered dossier
(7R)-7-(4-carboxybutanamido)cephalosporanate amidohydrolase (enzyme substance)
611-406-8 56645-46-6 Cease Manufacture Full Joint Cease manufacture 01-10-2018 View substance registered dossier
608-630-3 31528-46-8 Cease Manufacture Full Joint Cease manufacture 10-01-2019 View substance registered dossier
(8Z)-16-{[(2R,4S,5S)-6-[(acetyloxy)methyl]-3-{[(2S,4S,5S)-6-[(acetyloxy)methyl]-3,4,5-trihydroxyoxan-2-yl]oxy}-4,5-dihydroxyoxan-2-yl]oxy}heptadec-8-enoic acid; [(1S,4S,5S,8R,17Z,27S,31R)-28-[(acetyloxy)methyl]-4,5,30,31-tetrahydroxy-10-methyl-25-oxo-2,7,9,26,29-pentaoxatricyclo[³,⁸]hentriacont-17-en-6-yl]methyl acetate
941-809-7 - Active Full Joint ≥ 10 to < 100 tonnes 18-05-2022 View substance registered dossier
(8α,9R,8'''α,9'''R)-1,1'-[(2,3,5,6-tetrafluoro-1,4-phenylene)bis(methylene)]bis(6'-methoxycinchonan-1-ium-9-ol) dibromide
857-673-6 1879067-61-4 Active Full Joint ≥ 1 to < 10 tonnes 11-08-2022 View substance registered dossier
(aminoalkyl) hydrogen thiosulfate
- - Active Full Joint ≥ 1 to < 10 tonnes 05-01-2021 View substance registered dossier
No results were found
Registrant/Supplier Address Country Registration Status Name EC / List no. CAS no. Last update year Details
Sandoz GmbH Biochemiestr. 10 6250 Kundl Austria Austria Cease Manufacture (6S,7S)-7-Amino-3-(methoxymethyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid 435-680-1 - 2021 View substance registered dossier
Sensient Colors Oldmedow Road PE30 4LA King's Lynn Norfolk United Kingdom United Kingdom No longer Valid (7-Hydroxy-2-naphthyl)-trimethylammonium methyl sulphate 807-380-4 377734-55-9 2021 View substance registered dossier
LABORATORIOS SERVIER S.L. RIO JARAMA 59 45007 TOLEDO Spain Spain Active (7-Methoxy-3,4-dihydronaphthalen-1-yl)acetonitrile 617-813-7 861960-34-1 - View substance registered dossier
EGIS Pharmaceuticals PLC Keresztúri út 30-38 H-1106 Budapest Hungary Hungary Active (7-Methoxy-3,4-dihydronaphthalen-1-yl)acetonitrile 617-813-7 861960-34-1 - View substance registered dossier
EGIS Pharmaceuticals PLC Keresztúri út 30-38 H-1106 Budapest Hungary Hungary Active (7-methoxynaphthalen-1-yl)acetonitrile 461-670-1 - - View substance registered dossier
MSD International GmbH (Ballydine Branch) Ballydine - Kilsheelan 0 Clonmel Ireland Ireland Active (7R)-4-(5-Chloro-1,3-benzoxazol-2-yl)-7-methyl-1,4-diazepan-1-ium chloride 690-742-7 1266664-66-7 2019; 2020 View substance registered dossier
Centrient Pharmaceuticals Netherlands B.V. Alexander Fleminglaan 1 2613 AX Delft Netherlands Netherlands Cease Manufacture (7R)-7-(4-carboxybutanamido)cephalosporanate amidohydrolase (enzyme substance) 611-406-8 56645-46-6 2022 View substance registered dossier
Aspen Oss BV Kloosterstraat 6 5349 AB Oss Netherlands Netherlands Cease Manufacture (8R,9S,10R,13S,14S,17R)-17-ethynyl-17-hydroxy-13-methyl-1,2,8,9,10,11,12,14,15,16-decahydrocyclopenta[a]phenanthren-3-one 608-630-3 31528-46-8 2022 View substance registered dossier
Evonik Operations GmbH Rellinghauser Straße 1-11 45128 Essen Germany Germany Active (8Z)-16-{[(2R,4S,5S)-6-[(acetyloxy)methyl]-3-{[(2S,4S,5S)-6-[(acetyloxy)methyl]-3,4,5-trihydroxyoxan-2-yl]oxy}-4,5-dihydroxyoxan-2-yl]oxy}heptadec-8-enoic acid; [(1S,4S,5S,8R,17Z,27S,31R)-28-[(acetyloxy)methyl]-4,5,30,31-tetrahydroxy-10-methyl-25-oxo-2,7,9,26,29-pentaoxatricyclo[³,⁸]hentriacont-17-en-6-yl]methyl acetate 941-809-7 - 2022 View substance registered dossier
Evonik Fermas s.r.o. Slovenská Ľupča 938 976 13 Slovenská Ľupča Slovakia Slovakia Active (8Z)-16-{[(2R,4S,5S)-6-[(acetyloxy)methyl]-3-{[(2S,4S,5S)-6-[(acetyloxy)methyl]-3,4,5-trihydroxyoxan-2-yl]oxy}-4,5-dihydroxyoxan-2-yl]oxy}heptadec-8-enoic acid; [(1S,4S,5S,8R,17Z,27S,31R)-28-[(acetyloxy)methyl]-4,5,30,31-tetrahydroxy-10-methyl-25-oxo-2,7,9,26,29-pentaoxatricyclo[³,⁸]hentriacont-17-en-6-yl]methyl acetate 941-809-7 - 2016; 2019; 2021; 2022 View substance registered dossier
Syngenta Hellas Single Member S.A.C.I. Anthousas Avenue 153 49 Anthousa - Attiki Greece Greece Active (8α,9R,8'''α,9'''R)-1,1'-[(2,3,5,6-tetrafluoro-1,4-phenylene)bis(methylene)]bis(6'-methoxycinchonan-1-ium-9-ol) dibromide 857-673-6 1879067-61-4 - View substance registered dossier
RSI ChemRep Europe Ltd (S001) 27-30 Merchants Quay Merchants House 8 Dublin Ireland Ireland Active (aminoalkyl) hydrogen thiosulfate - - 2017; 2021 View substance registered dossier

In this table, you will find all public data submitted to ECHA in REACH registration dossiers by substance manufacturers, importers, or their representatives, as laid out by the REACH Regulation (see Understanding REACH regulation).

ECHA makes available this information as REACH registered substance factsheets, which contain the full set of non-confidential information from related registration dossiers for a substance. Depending on the number of registrations that have been made for a substance, one factsheet can thus represent data from anything between hundreds of registration dossiers in a joint submission, to data from just one registration dossier.

As noted in the Legal Notice of the ECHA website, ECHA does not give any guarantees or warranties regarding the quality and correctness of the published information. The information in the portal is published ‘as provided’ by industry, and its accuracy has not been verified by ECHA. ECHA is also not in a position to intervene with, edit or correct the published data; this can only be done by the registrant responsible for its submission. Please also note that the information may be protected and its use may require prior permission from its owner (see the ECHA website Legal Notice more details).

In the portal results table are presented:

  • Public substance identity – the best available non-confidential substance name, EC, and CAS numbers.
  • Registration status – indicating the calculated registration status for the whole factsheet: Active – is being manufactured or imported to the EEA by one or more registrants; Cease Manufacture - is no longer being manufactured or imported above 1 tone per calendar year. All registrants of the substance have reported a cease of manufacture or import; or No longer valid - no longer considered registered under REACH and not currently allowed to be manufactured or imported to the EEA, until the substance is registered again.
  • Registration type – indicating whether a given factsheet contains data from a REACH full registration, REACH intermediate registration, or only a limited set of data inherited from a NONS notification.
  • Submission type – indicating whether the data in a given factsheet was submitted jointly or individually.
  • Total tonnage band – calculated per factsheet from all contributing registrations, based on the estimated quantity of the substance placed on the market. Data is excluded from dossiers where the tonnage is claimed confidential, from Intermediate registration dossiers, and from NONs which have not been updated.
  • Last updated – indicating the date on which this registered substance factsheet was last modified with new or updated data, based on an industry submission.
  • Link to the full factsheet.

A subset of the key chemical properties (physico-chemical, environmental fate, ecotoxicological and toxicological data) of registered substances can be searched and accessed via the OECD eChemPortal.