Registered substances

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New Data Availability System

A new Data Availability System is being developed by ECHA. To begin with this system will take over the responsibility of making REACH registration data available, once it is ready. We expect the first version to be publicly available by the end of January 2024.

Since ECHA aims to devote our maximum effort to this new system, we can no longer maintain REACH registration data on the current Dissemination Platform. As such once the IUCLID format change begins on 19th May 2023 we will no longer update REACH registered substance factsheets. The factsheets will remain online, but will not be updated.

New and updated REACH registration submissions, as well as all registrations on file, will be made available in the new system when it is ready. We will inform you of what you can expect in the new System, along with details of when and where to find it.

We appreciate your understanding in the meantime.

DISSEMINATION
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REACH - Registration, Evaluation, Authorisation and Restriction of Chemicals Regulation

Registered Substances Factsheets

Substances which have been registered and can be placed on the EEA market by those companies with a valid registration

Showing 1 - 200 of 26,866 results.

Name	EC / List no.	CAS no.	Registration Status	Registration type	Submission type	Total tonnage band	Last Updated	Details
((2R,3R,4R,5R)-3-(benzoyloxy)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-4-fluoro-4-methyltetrahydrofuran-2-yl)methyl benzoate	807-766-2	863329-65-1	Cease Manufacture	Intermediate	Individual	Cease manufacture	01-02-2016	View substance registered dossier
((4S,4aR,7S,7aR)-4,7-dimethylhexahydrocyclopenta[c]pyran-1(3H)-one	953-513-5	-	Cease Manufacture	Full	Joint	Cease manufacture	04-08-2021	View substance registered dossier
(+)-2-amino-1-butanol	227-475-9	5856-62-2	Cease Manufacture	Intermediate	Joint	Cease manufacture	10-04-2017	View substance registered dossier
(+-)-2,4-dihydro-4-[4-[4-(4-methoxyphenyl)-1-piperazinyl]phenyl]-2-(1-methylpropyl)-3H-1,2,4-triazol-3-one	607-685-0	252964-68-4	Cease Manufacture	Full	Joint	Cease manufacture	29-05-2018	View substance registered dossier
(+-)-TRANS-3-METHYL-1-[(4-METHYLPHENYL)SULFONYL]-4-PHENYLPIPERIDINE-4-CARBONITRILE	607-821-9	25858-24-6	Cease Manufacture	Intermediate	Joint	Cease manufacture	23-10-2012	View substance registered dossier
(+/-) tetrahydrofurfuryl (R)-2-[4-(6-chloroquinoxalin-2-yloxy)phenyloxy]propionate PANTERA; QUIZALOFOP-P-TEFURYL	414-200-4	200509-41-7	Cease Manufacture	NONS	Joint	Cease manufacture	15-12-2008	View substance registered dossier
(+/-)-(R,S)-6-fluoro-3,4-dihydro-2-oxiranyl-2H-1-benzopyran T001448	419-630-6	793669-26-8	Cease Manufacture	NONS	Joint	Cease manufacture	18-08-2010	View substance registered dossier
(+/-)-[(R,R)and(R,S)]-6-fluoro-3,4-dihydro-2-oxiranyl-2H-1-benzopyran T001446	419-600-2	99199-90-3	Cease Manufacture	NONS	Individual	Cease manufacture	12-09-2012	View substance registered dossier
(1-chlorocyclohexyl) cyclohexyl ketone	280-893-3	83803-75-2	Cease Manufacture	Intermediate	Joint	Cease manufacture	08-06-2016	View substance registered dossier
(1-ethoxy-1-oxopropan-2-yl) 5-[2-chloro-4-(trifluoromethyl)phenoxy]-2-nitrobenzoate	616-466-9	77501-63-4	Cease Manufacture	Full	Individual	Cease manufacture	13-05-2013	View substance registered dossier
(1-methylethylidene)di-4,1-phenylenetetraphenyl diphosphate	425-220-8	5945-33-5	Cease Manufacture	Full	Individual	Cease manufacture	20-11-2012	View substance registered dossier
(10aS)-methyl 10a-methoxy-7-methyl-4,6,6a,7,8,9,10,10a-octahydroindolo[4,3-fg]quinoline-9-carboxylate	607-239-5	23495-64-9	Cease Manufacture	Full	Joint	Cease manufacture	28-05-2018	View substance registered dossier
(10S)-10,11-Dihydro-10-hydroxy-5H-dibenz[b,f]azepine-5-carboxamide	810-248-9	104746-04-5	Cease Manufacture	Intermediate	Individual	Cease manufacture	09-06-2015	View substance registered dossier
(17α)-17-hydroxy-3-oxoandrost-4-ene-17-carbonitrile	278-780-9	77881-13-1	Cease Manufacture	Intermediate	Joint	Cease manufacture	22-10-2012	View substance registered dossier
(1E)-N-hydroxy-1-(naphthalen-1-yl)ethanimine	700-765-7	100485-51-6	Cease Manufacture	Intermediate	Individual	Cease manufacture	07-12-2012	View substance registered dossier
(1R)-1-[(4R,4aR,8aS)-2,6-bis(3,4-dimethylphenyl)tetrahydro[1,3]dioxino[5,4-d][1,3]dioxin-4-yl]ethane-1,2-diol	413-110-2	1171816-77-5	Cease Manufacture	Full	Individual	Cease manufacture	02-04-2013	View substance registered dossier
(1R)-1-[(4R,4aR,8aS)-2,6-bis(3,4-dimethylphenyl)tetrahydro[1,3]dioxino[5,4-d][1,3]dioxin-4-yl]ethane-1,2-diol	413-110-2	1171816-77-5	Cease Manufacture	Full	Individual	Cease manufacture	17-08-2012	View substance registered dossier
(1R)-1-[(4R,4aR,8aS)-2,6-bis(3,4-dimethylphenyl)tetrahydro[1,3]dioxino[5,4-d][1,3]dioxin-4-yl]ethane-1,2-diol	413-110-2	1171816-77-5	Cease Manufacture	Full	Individual	Cease manufacture	21-05-2013	View substance registered dossier
(1R,12R)-9-methoxy-4-methyl-11-oxa-4-azatetracyclo[8.6.1.0^{1,12}.0^{6,17}]heptadeca-6(17),7,9,15-tetraen-14-one	428-690-2	1668-86-6	Cease Manufacture	NONS	Individual	Cease manufacture	23-11-2010	View substance registered dossier
(1R,2S,10R,11S,15S)-2,15-dimethyl-4-(morpholin-4-yl)-13-(pyrrolidin-1-yl)tetracyclo[8.7.0.0²,⁷.0¹¹,¹⁵]heptadecane-5,14-diol	601-595-5	119302-20-4	Cease Manufacture	Full	Individual	Cease manufacture	09-07-2015	View substance registered dossier
(1R,2S,3S,4R)-3-((2-chloro-5-fluoropyrimidin-4-yl)amino)bicyclo[2.2.2]octane-2-carboxylic acid	821-184-6	1777721-60-4	Cease Manufacture	Full	Joint	Cease manufacture	28-02-2019	View substance registered dossier
(1R,2S,3S,4R)-3-((5-fluoro-2-(5-fluoro-1-tosyl-1H-pyrrolo[2,3-b]pyridin-3-yl)pyrimidin-4-yl)amino)bicyclo[2.2.2]octane-2-carboxylic acid	821-185-1	1777721-63-7	Cease Manufacture	Full	Joint	Cease manufacture	28-02-2019	View substance registered dossier
(1R,2S,5R)-2-Isopropyl-5-methylcyclohexyl (2R,5R)-5-hydroxy-1,3-oxathiolane-2-carboxylate	604-569-1	147126-62-3	Cease Manufacture	Intermediate	Joint	Cease manufacture	13-08-2014	View substance registered dossier
(1R,2S,8S,10S,11S,13R,14R,15S,17S)-1,8-difluoro- 14,17dihydroxy-2,13,15-trimethyl-5-oxotetracyclo[8.7.0.0^{2,7}.0^{11,15}]heptadeca-3,6-diene-14-carbothioic S-acid	617-081-9	80473-92-3	Cease Manufacture	Full	Joint	Cease manufacture	21-11-2016	View substance registered dossier
(1R,3R,4S,5R)-methyl 3-acetoxy-4-hydroxy-5-(tosyloxy)cyclohexanecarboxylate	813-307-7	1104200-22-7	Cease Manufacture	Intermediate	Individual	Cease manufacture	11-01-2017	View substance registered dossier
(1R,3S,5S)-8-benzyl-8-azabicyclo[3.2.1]octan-3-amine fumarate	943-085-8	-	Cease Manufacture	Intermediate	Individual	Cease manufacture	04-04-2016	View substance registered dossier
(1R,4R,5S)-6,6-dimethyl-4-(tribromomethyl)-3-oxabicyclo[3.1.0]hexan-2-one	619-738-5	87305-03-1	Cease Manufacture	Intermediate	Individual	Cease manufacture	19-08-2008	View substance registered dossier
(1R,4S,4aS,8aR)-9-(dichloromethylene)-1,4,4a,8a-tetrahydro-1,4-methanonaphthalene-5,8-dione	807-377-8	1263184-85-5	Cease Manufacture	Intermediate	Joint	Cease manufacture	21-08-2017	View substance registered dossier
(1R,7S)-10,10-Dimethyl-3-thia-4-azatricyclo[5.2.1.0(1,5)]dec-4-ene 3,3-dioxide	621-464-6	107869-45-4	Cease Manufacture	Intermediate	Individual	Cease manufacture	04-06-2013	View substance registered dossier
(1S)-1-cyclopropylethanamine; (2R)-2-hydroxy-2-phenyl-acetic acid	946-290-0	2246580-61-8	Cease Manufacture	Intermediate	Joint	Cease manufacture	01-10-2020	View substance registered dossier
(1S)-2,3,4,6-TETRA-O-ACETYL-1,5-ANHYDRO-1-(3-{[5-(4-FLUOROPHENYL)THIOPHEN-2-YL]METHYL}-4-METHYLPHENYL)-D-GLUCITOL	617-901-5	866607-35-4	Cease Manufacture	Full	Joint	Cease manufacture	23-06-2020	View substance registered dossier
(1S)-2,3,4,6-TETRA-O-ACETYL-1,5-ANHYDRO-1-(3-{[5-(4-FLUOROPHENYL)THIOPHEN-2-YL]METHYL}-4-METHYLPHENYL)-D-GLUCITOL	617-901-5	866607-35-4	Cease Manufacture	Intermediate	Individual	Cease manufacture	10-10-2014	View substance registered dossier
(1S,2R)-1-((2R,3R,4S,6S)-3-acetamido-4-(diallylamino)-6-hydroxy-6-(methoxycarbonyl)tetrahydro-2H-pyran-2-yl)propane-1,2,3-triyl triacetate	700-779-3	-	Cease Manufacture	Intermediate	Individual	Cease manufacture	31-05-2012	View substance registered dossier
(1S,3R,4R,5R)-methyl 3-acetoxy-4,5-dihydroxycyclohexanecarboxylate	839-204-7	1104200-21-6	Cease Manufacture	Intermediate	Individual	Cease manufacture	03-06-2019	View substance registered dossier
(1S,3R,4R,5S)-methyl 3-acetoxy-5-azido-4-(((2S,3S,4R,5R,6S)-3,4,5-tris(benzyloxy)-6-methyltetrahydro-2H-pyran-2-yl)oxy)cyclohexanecarboxylate	813-345-4	1104200-23-8	Cease Manufacture	Intermediate	Individual	Cease manufacture	20-03-2017	View substance registered dossier
(2,2,8-trimethyl-4H-[1,3]dioxino[4,5-c]pyridin-5-yl)methanol hydrochloride	700-391-4	6953-28-2	Cease Manufacture	Intermediate	Individual	Cease manufacture	02-12-2010	View substance registered dossier
(2,4-Difluorophenyl)(4-Fluorophenyl)methanone	813-638-7	80512-44-3	Cease Manufacture	Intermediate	Individual	Cease manufacture	23-01-2018	View substance registered dossier
(2,5-dimethylphenyl)-acetyl chloride	470-780-9	-	Cease Manufacture	NONS	Individual	Cease manufacture	28-03-2018	View substance registered dossier
(2-hydroxyethyl)(3-hydroxypropyl)dimethylammonium chloride	278-860-3	78182-00-0	Cease Manufacture	Intermediate	Individual	Cease manufacture	30-08-2011	View substance registered dossier
(2R)-2-(2,4-difluorophenyl)-1,1-difluoro-1-{5-[4-(2,2,2-trifluoroethoxy)phenyl]pyridin-2-yl}-3-(1H-tetrazol-1-yl)propan-2-ol	841-499-2	1340593-59-0	Cease Manufacture	Full	Joint	Cease manufacture	25-08-2020	View substance registered dossier
(2R,3R,4R,5R)-5-(4-benzamido-2-oxopyrimidin-1(2H)-yl)-2-(benzoyloxymethyl)-4-fluoro-4-methyltetrahydrofuran-3-yl benzoate	807-677-9	817204-32-3	Cease Manufacture	Intermediate	Individual	Cease manufacture	12-01-2016	View substance registered dossier
(2R,3R,4S,5R)-2-(acetoxymethyl)-6-oxotetrahydro-2H-pyran-3,4,5-triyl triacetate	612-107-5	61259-48-1	Cease Manufacture	Intermediate	Individual	Cease manufacture	29-09-2015	View substance registered dossier
(2S)-2-[[(2S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl]amino]propanoic acid	406-310-6	-	Cease Manufacture	Intermediate	Individual	Cease manufacture	22-11-2011	View substance registered dossier
(2S)-2-Aminobutyramide Hydrochloride	471-490-5	7682-20-4	Cease Manufacture	NONS	Individual	Cease manufacture	15-12-2008	View substance registered dossier
(2S)-2-{[(1E)-(5-chloro-2-hydroxyphenyl)(phenyl)methylene]amino}-3-methylbutanoic acid	609-516-6	38075-43-3	Cease Manufacture	Intermediate	Joint	Cease manufacture	18-01-2018	View substance registered dossier
(2S)-5-methoxy-N-propyl-1,2,3,4-tetrahydronaphthalen-2-amine hydrochloride (1:1)	695-797-0	93601-86-6	Cease Manufacture	Full	Joint	Cease manufacture	04-07-2018	View substance registered dossier
(2S)-5-methoxy-N-propyl-1,2,3,4-tetrahydronaphthalen-2-aminium (2R)-(2-chlorophenyl)(hydroxy)acetate	814-350-4	1352917-66-8	Cease Manufacture	Full	Joint	Cease manufacture	04-07-2018	View substance registered dossier
(2S)-{[(benzyloxy)carbonyl]amino}(cyclohexyl)acetic acid	478-210-0	69901-75-3	Cease Manufacture	Intermediate	Individual	Cease manufacture	05-11-2012	View substance registered dossier
(2S,3R,4R,5S,6R)-3,4,5-tris(benzyloxy)-2-methyl-6-(p-tolylthio)tetrahydro-2H-pyran	835-228-7	211801-54-6	Cease Manufacture	Intermediate	Individual	Cease manufacture	05-03-2019	View substance registered dossier
(2S,3R,4S,5R,6R)-6-(acetoxymethyl)-2-(3-((5-(4-fluorophenyl)thiophen-2-yl)methyl)-4-methylphenyl)-2-hydroxytetrahydro-2H-pyran-3,4,5-triyl triacetate	921-285-6	1071929-02-6	Cease Manufacture	Intermediate	Individual	Cease manufacture	29-09-2015	View substance registered dossier
(2S,3S)-2,3-Bis((4-methoxybenzoyl)oxy)succinic acid	606-247-6	191605-10-4	Cease Manufacture	Intermediate	Individual	Cease manufacture	12-12-2008	View substance registered dossier
(2S,3S)-3-amino-N-cyclopropyl-2-hydroxyhexanamide hydrochloride	478-270-8	-	Cease Manufacture	Intermediate	Individual	Cease manufacture	05-11-2012	View substance registered dossier
(2S,3S,5R)-2-hexyl-3-hydroxy-5-(phenylmethoxy)-Hexadecanoic acid compd. with (S)-α-methylbenzenemethanamine (1:1)	604-018-5	137433-01-3	Cease Manufacture	Intermediate	Joint	Cease manufacture	04-12-2012	View substance registered dossier
(2α,4aα,8β)-hexahydro-1,1,5,5-tetramethyl-2H-2,4a-methanonaphthalen-8(5H)-one	249-648-8	29461-13-0	Cease Manufacture	Full	Joint	Cease manufacture	24-12-2019	View substance registered dossier
(3 β, 5 α, 6β)-3-(acetyloxy)-5-bromo-6-hydroxy-androstan-17-one 17-KETOBROMOHYDRINE	419-790-7	4229-69-0	Cease Manufacture	NONS	Individual	Cease manufacture	10-11-2008	View substance registered dossier
(3,4-Dimethoxy-bicyclo[4.2.0]octa-1,3,5-trien-7-yl)-methylamine	917-818-7	73344-75-9	Cease Manufacture	Intermediate	Individual	Cease manufacture	19-01-2012	View substance registered dossier
(3-aminophenyl)pyridin-3-ylmethanone	428-230-0	79568-06-2	Cease Manufacture	NONS	Individual	Cease manufacture	10-11-2008	View substance registered dossier
(3-aminophenyl)urea	247-201-1	25711-72-2	Cease Manufacture	Full	Joint	Cease manufacture	10-05-2017	View substance registered dossier
(3-aminophenyl)uronium chloride	261-858-1	59690-88-9	Cease Manufacture	Full	Joint	Cease manufacture	29-04-2013	View substance registered dossier
(3-endo)-8-methyl-8-azabicyclo[3.2.1]oct-3-yl methanesulfonate	700-367-3	35130-97-3	Cease Manufacture	Intermediate	Individual	Cease manufacture	09-02-2010	View substance registered dossier
(3aS,4R,5S,6S,8R,9R,9aR,10R)-6-ethenyl-5-hydroxy-4,6,9,10-tetramethyl-1-oxodecahydro-3a,9-propanocyclopenta[8]annulen-8-yl[(methylsulfonyl)oxy]acetate	700-396-1	60924-38-1	Cease Manufacture	Intermediate	Individual	Cease manufacture	09-02-2010	View substance registered dossier
(3beta)-17-(3-pyridinyl)androsta-5,16-dien-3-yl acetate compound with (2R,3R)-tartaric acid and methanol (1 : 1 : 1.5)	931-336-4	-	Cease Manufacture	Intermediate	Individual	Cease manufacture	13-09-2012	View substance registered dossier
(3E)-2-chloro-3-(hydroxymethylene)cyclohexene-1-carbaldehyde	801-656-8	1416808-92-8	Cease Manufacture	Full	Joint	Cease manufacture	13-04-2017	View substance registered dossier
(3R)-3-(2-amino-2-oxoethyl)-5-methylhexanoic acid	605-923-8	181289-33-8	Cease Manufacture	Intermediate	Joint	Cease manufacture	13-05-2015	View substance registered dossier
(3R,4R,5R,6R,9R,10Z,11R,12S,14S)-6-{[(2S,3R,4S,6R)-4-(dimethylamino)-3-hydroxy-6-methyltetrahydro-2H-pyran-2-yl]oxy}-14-ethyl-7,12,13-trihydroxy-4-{[(2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyltetrahydro-2H-pyran-2-yl]oxy}-3,5,7,9,11,13-hexamethyloxacyclotetradecane-2,10-dione 10-oxime	603-883-6	134931-01-4	Cease Manufacture	Intermediate	Individual	Cease manufacture	25-10-2012	View substance registered dossier
(3R,4S,5S,6R,7R,9R,10E,11S,12R,13S,14R)-6-[(2S,3R,4S,6R)-4-dimethylamino-3-hydroxy-6-methyloxan-2-yl]oxy-14-ethyl-7,12,13-trihydroxy-10-hydroxyimino-4-[(2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyloxan-2-yl]oxy-3,5,7,9,11,13-hexamethyl-1-oxacyclotetradecan-2-one	603-467-4	13127-18-9	Cease Manufacture	Intermediate	Individual	Cease manufacture	22-10-2010	View substance registered dossier
(3R,7aR)-3-tert-butyl-1,5-dioxodihydro-1H-pyrrolo[1,2-c][1,3]oxazole-7a(5H)-carbaldehyde	812-036-1	1214741-19-1	Cease Manufacture	Intermediate	Individual	Cease manufacture	28-04-2016	View substance registered dossier
(3R,7aR)-3-tert-butyl-7a-{methoxy[(trimethylsilyl)oxy]methyl}dihydro-1H-pyrrolo[1,2-c][1,3]oxazole-1,5(6H)-dione	942-823-6	-	Cease Manufacture	Intermediate	Individual	Cease manufacture	03-11-2015	View substance registered dossier
(3R,7aS)-3-tert-butyldihydro-1H-pyrrolo[1,2-c]oxazole-1,5(6H)-dione	810-392-2	171284-84-7	Cease Manufacture	Intermediate	Individual	Cease manufacture	07-09-2015	View substance registered dossier
(3S,4aS,8aS)-2-[(2R,3S)-3-amino-2-hydroxy-4-phenylbutyl]-N-tert-butyldecahydroisoquinoline-3-carboxamide PTH-AA	430-230-0	136522-17-3	Cease Manufacture	NONS	Individual	Cease manufacture	13-09-2010	View substance registered dossier
(3S,4aS,8aS)-N-tert-Butyldecahydro-3-isoquinolinecarboxamide	420-380-5	136465-81-1	Cease Manufacture	Intermediate	Individual	Cease manufacture	29-10-2012	View substance registered dossier
(3S,5R,8aS)-3-phenyl-3,5,6,7,8,8a-hexahydro-2H-oxazolo[3,2-a]pyridine-5-carbonitrile	634-598-5	106565-71-3	Cease Manufacture	Intermediate	Individual	Cease manufacture	15-10-2014	View substance registered dossier
(3S,6R,7E,9R,10R,12R,14S,15E,17E,19E,21S,23S,26R,27R,34aS)-9,10,12,13,14,21,22,23,24,25,26,27,32,33,34,34a-hexadecahydro-9,27-dihydroxy-3-[(1R)-2-[(1S,3R,4R)-4-hydroxy-3-methoxycyclohexyl]-1-methylethyl]-10,21-dimethoxy-6,8,12,14,20,26-hexamethyl-23,27-epoxy-3H-pyrido[2,1-c][1,4]-oxaazacyclohentriacontine-1,5,11,28,29(4H,6H,31H)-pentone	610-965-5	53123-88-9	Cease Manufacture	Intermediate	Individual	Cease manufacture	26-08-2014	View substance registered dossier
(3S-cis)-3,6-dimethyl-1,4-dioxane-2,5-dione	224-832-0	4511-42-6	Cease Manufacture	Full	Individual	Cease manufacture	17-08-2015	View substance registered dossier
(4-(4-aminophenyl)(4-iminocyclohexa-2,5-dienylidene)methyl)-2-methylaniline hydrochloride	211-189-6	632-99-5	Cease Manufacture	Full	Joint	Cease manufacture	25-03-2018	View substance registered dossier
(4-benzylpiperazin-1-yl)(cyclopropyl)methanone hydrochloride	816-907-7	1294454-93-5	Cease Manufacture	Intermediate	Joint	Cease manufacture	28-05-2020	View substance registered dossier
(4-Chloro-2-fluoro-phenyl)-acetonitrile	642-783-7	75279-53-7	Cease Manufacture	Intermediate	Individual	Cease manufacture	30-03-2016	View substance registered dossier
(4-cyclopropyl-6-methyl-pyrimidin-5-yl)boronic acid	826-639-2	1817776-86-5	Cease Manufacture	Intermediate	Joint	Cease manufacture	20-07-2020	View substance registered dossier
(4-ethoxyphenyl)(3-(4-fluoro-3-phenoxyphenyl)propyl)dimethylsilane SILANEOPHAN	405-020-7	105024-66-6	Cease Manufacture	NONS	Joint	Cease manufacture	10-11-2008	View substance registered dossier
(4R)-Tetrahydro-4-hydroxy-4-methyl-2H-Pyran-2-one	433-160-9	-	Cease Manufacture	NONS	Individual	Cease manufacture	10-11-2008	View substance registered dossier
(4S,5S)-5-hydroxy-2-methyl-3,4,5,6-tetrahydropyrimidine-4-carboxylic acid HYDROXYECTOIN	442-870-8	-	Cease Manufacture	NONS	Joint	Cease manufacture	10-11-2008	View substance registered dossier
(4Z)-3-methyl-N-nitro-5-{[2-(phenylsulfanyl)-1,3-thiazol-5-yl]methyl}-1,3,5-oxadiazinan-4-imine	427-600-9	192439-46-6	Cease Manufacture	NONS	Individual	Cease manufacture	10-11-2008	View substance registered dossier
(5,6-Dimethyl-9-oxo-9H-xanthen-4-yl)acetic acid	700-141-4	117570-53-3	Cease Manufacture	Intermediate	Individual	Cease manufacture	22-06-2010	View substance registered dossier
(5α)-Androsta-2,16-dien-17-yl acetate	610-545-1	50588-42-6	Cease Manufacture	Full	Individual	Cease manufacture	21-05-2015	View substance registered dossier
(6ALPHA,11BETA,16ALPHA,17ALPHA)-6,9-DIFLUORO-11-HYDRO XY-16-METHYL-3-OXO-17- (1-OXOPROPOXY)ANDROSTA-1,4-DIENE-CARBOTHIOIC ACID	617-084-5	80474-45-9	Cease Manufacture	Full	Joint	Cease manufacture	20-12-2016	View substance registered dossier
(6R,7R)-3-[(5-amino-4-{[(2-aminoethyl)carbamoyl]amino}-1-methyl-1H-pyrazol-2-ium-2-yl)methyl]-7-{[(2Z)-2-(5-amino-1,2,4-thiadiazol-3-yl)-2-{[(2-carboxypropan-2-yl)oxy]imino}acetyl]amino}-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate trifluoroacetate (1:3)	939-998-6	-	Cease Manufacture	Intermediate	Joint	Cease manufacture	24-11-2014	View substance registered dossier
(6R,7R)-3-[[(Aminocarbonyl)oxy]methyl]-7-[[(2Z)-2-furanyl(methoxyimino)acetyl]amino]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-en-2-carboxylic acid, 1-butylammonium salt	439-350-8	-	Cease Manufacture	NONS	Individual	Cease manufacture	22-12-2010	View substance registered dossier
(6R,7R)-7-[[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-methoxyiminoacetyl]amino]-3-(furan-2-carbonylsulfanylmethyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid;hydrochloride	600-507-2	103980-44-5	Cease Manufacture	Intermediate	Joint	Cease manufacture	03-04-2018	View substance registered dossier
(6R,7R)-7-amino-3-(5H-imidazo[1,2-b]pyridazin-1-ylmethyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid;hydroiodide	606-382-0	197897-11-3	Cease Manufacture	Intermediate	Individual	Cease manufacture	20-04-2018	View substance registered dossier
(6R,7R)-7-amino-3-{[(furan-2-ylcarbonyl)sulfanyl]methyl}-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid	617-065-1	80370-59-8	Cease Manufacture	Intermediate	Joint	Cease manufacture	03-04-2018	View substance registered dossier
(6R,7R)-7-{[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetyl]amino}-3-({[5-(carboxymethyl)-4-methyl-1,3-thiazol-2-yl]sulfanyl}methyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid	700-301-3	69739-16-8	Cease Manufacture	Intermediate	Individual	Cease manufacture	04-06-2009	View substance registered dossier
(6R-trans)-1-((7-Ammonio-2-carboxylato-8-oxo-5-thia-1-azabicyclo-(4.2.0)oct-2-en-3-yl)methyl)pyridinium iodide	423-260-0	100988-63-4	Cease Manufacture	NONS	Individual	Cease manufacture	29-10-2012	View substance registered dossier
(6R-trans)-7-amino-3-[[[5-(carboxymethyl)-4-methyl-2-thiazolyl]thio]methyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid	619-847-8	111298-82-9	Cease Manufacture	Intermediate	Individual	Cease manufacture	26-03-2009	View substance registered dossier
(6R-trans)-7-amino-8-oxo-3-[[(1,2,5,6-tetrahydro-2-methyl-5,6-dioxo-1,2,4-triazin-3-yl)thio]methyl]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid	261-491-7	58909-56-1	Cease Manufacture	Full	Joint	Cease manufacture	03-05-2018	View substance registered dossier
(6S,7S)-7-Amino-3-(methoxymethyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid	435-680-1	-	Cease Manufacture	Full	Individual	Cease manufacture	17-05-2018	View substance registered dossier
(6S,9R,10S,11S,13S,16R,17R)-6,9-difluoro-11,17-dihydroxy-10,13,16-trimethyl-3-oxo-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthrene-17-carboxylic acid	434-320-0	-	Cease Manufacture	NONS	Joint	Cease manufacture	15-11-2012	View substance registered dossier
(7R)-7-(4-carboxybutanamido)cephalosporanate amidohydrolase (enzyme substance)	611-406-8	56645-46-6	Cease Manufacture	Full	Joint	Cease manufacture	01-10-2018	View substance registered dossier
(8R,9S,10R,13S,14S,17R)-17-ethynyl-17-hydroxy-13-methyl-1,2,8,9,10,11,12,14,15,16-decahydrocyclopenta[a]phenanthren-3-one	608-630-3	31528-46-8	Cease Manufacture	Full	Joint	Cease manufacture	10-01-2019	View substance registered dossier
(Benzyloxycarbonyl)methyl 3-[5-acetamido-4-(2-chloro-4,6-dinitrophenylazo)-2-methoxyanilino]propionate	436-000-6	159010-67-0	Cease Manufacture	NONS	Individual	Cease manufacture	10-11-2008	View substance registered dossier
(Benzyloxycarbonyl)methyl 4-(1-Butyl-5-cyano-1,6-dihydro-2-hydroxy-4-methyl-6-oxo-3-pyridylazo)-benzoate	442-520-4	-	Cease Manufacture	NONS	Individual	Cease manufacture	10-11-2008	View substance registered dossier
(Bromomethyl)cyclobutane	700-027-4	17247-58-4	Cease Manufacture	Intermediate	Individual	Cease manufacture	31-08-2011	View substance registered dossier
(Bromomethyl)cyclobutane	700-027-4	17247-58-4	Cease Manufacture	Intermediate	Joint	Cease manufacture	14-12-2011	View substance registered dossier
(C12-C14)tert-alkylammonium methylphosphonate CD 23-404	404-750-3	119415-07-5	Cease Manufacture	NONS	Individual	Cease manufacture	10-11-2008	View substance registered dossier
(chloromethyl)bis(4-fluorophenyl)methylsilane H6572	401-200-4	85491-26-5	Cease Manufacture	Full	Joint	Cease manufacture	29-10-2012	View substance registered dossier
(cyclohex-3-en-1-yl)methyl 2-hydroxypropanoate	946-283-2	1864727-96-7	Cease Manufacture	Full	Joint	Cease manufacture	18-01-2019	View substance registered dossier
(E)-1,4-dibromobut-2-ene	212-472-7	821-06-7	Cease Manufacture	Intermediate	Joint	Cease manufacture	18-05-2018	View substance registered dossier
(E)-3-(2-chlorophenyl)-2-(4-fluorophenyl)propenal DPP	410-980-5	112704-51-5	Cease Manufacture	NONS	Individual	Cease manufacture	10-11-2008	View substance registered dossier
(E)-5-benzyl-1-(2-chloro-1,3-thiazol-5-ylmethyl)-3-methyl-N-nitro-1,3,5-triazinan-2-imine	606-753-7	213967-55-6	Cease Manufacture	Intermediate	Individual	Cease manufacture	15-12-2010	View substance registered dossier
(E)-methyl 2-acetyloct-2-enoate	807-427-9	228114-02-1	Cease Manufacture	Intermediate	Joint	Cease manufacture	16-10-2014	View substance registered dossier
(E,Z)-2,6-dimethylocta-2,4,6-triene	230-603-6	7216-56-0	Cease Manufacture	Full	Joint	Cease manufacture	17-04-2018	View substance registered dossier
(R)-1-chloro-2,3-epoxypropane (R)-EPICHLOROHYDRIN	424-280-2	51594-55-9	Cease Manufacture	Intermediate	Joint	Cease manufacture	20-03-2018	View substance registered dossier
(R)-2-(2,4-Difluorphenyl)-1,1-difluor-3-(tetrazol-1-yl)-1-{5-[4-(2,2,2-trifluorethoxy)-phenyl]-2-pyridyl}-2-propanol-(R,R)-tartrate	845-262-4	1809816-36-1	Cease Manufacture	Full	Joint	Cease manufacture	30-09-2020	View substance registered dossier
(R)-3-chloropropane-1,2-diol	435-560-9	57090-45-6	Cease Manufacture	NONS	Individual	Cease manufacture	10-11-2008	View substance registered dossier
(RS)-3-dichloroacetyl-5-(2-furanyl)-2,2-dimethyloxazolidine	434-800-1	-	Cease Manufacture	Full	Individual	Cease manufacture	05-11-2020	View substance registered dossier
(S)-(+)-2-(2-Chlorophenyl)-2-hydroxyacetic acid	700-307-6	52950-19-3	Cease Manufacture	Intermediate	Individual	Cease manufacture	27-11-2009	View substance registered dossier
(S)-1,1-diphenyl-1,2-propanediol	443-220-6	46755-94-6	Cease Manufacture	NONS	Individual	Cease manufacture	26-01-2012	View substance registered dossier
(S)-2,6-Diamino-4,5,6,7-tetrahydrobenzothiazole	600-715-3	106092-09-5	Cease Manufacture	Intermediate	Joint	Cease manufacture	30-08-2012	View substance registered dossier
(S)-2-(1-aminopropyl)-5-fluoro-3-phenylquinazolin-4(3H)-one hydrochloride	942-180-1	-	Cease Manufacture	Intermediate	Individual	Cease manufacture	28-08-2015	View substance registered dossier
(S)-2-amino-3-(3,4-dimethoxyphenyl)-2-methylpropiononitrile monohydrochloride	219-823-3	2544-13-0	Cease Manufacture	Intermediate	Joint	Cease manufacture	03-12-2013	View substance registered dossier
(S)-2-Amino-6-propionylamino-4,5,6,7-tetrahydrobenzothiazole	600-709-0	106006-84-2	Cease Manufacture	Intermediate	Joint	Cease manufacture	05-07-2012	View substance registered dossier
(S)-2-Amino-6-propylamino-4,5,6,7-tetrahydrobenzothiazole	600-593-1	104632-26-0	Cease Manufacture	Intermediate	Individual	Cease manufacture	18-04-2011	View substance registered dossier
(S)-2-Hydroxy-3,3-dimethyl-4-butanolide	626-470-2	5405-40-3	Cease Manufacture	Full	Individual	Cease manufacture	05-07-2011	View substance registered dossier
(S)-3-(tert-butylamino)propane-1,2-diol	250-125-1	30315-46-9	Cease Manufacture	Full	Joint	Cease manufacture	27-08-2020	View substance registered dossier
(S)-3-benzyloxycarbonyl-1,2,3,4-tetrahydro-isoquinolinium 4-methylbenzenesulfonate BENZYL THIQ TOSYLATE; PD 114683-10; TIC-B	406-960-0	77497-97-3	Cease Manufacture	Intermediate	Individual	Cease manufacture	04-10-2012	View substance registered dossier
(S)-3-Hydroxytetrahydrofurane	425-090-2	-	Cease Manufacture	Intermediate	Joint	Cease manufacture	10-05-2010	View substance registered dossier
(S)-3-Methyl-1-(2-piperidine-1-phenyl)butylamine compound with N-Acetyl-L-glutamic acid	606-883-4	219921-94-5	Cease Manufacture	Intermediate	Individual	Cease manufacture	10-12-2014	View substance registered dossier
(S)-3-Methyl-1-(2-piperidinophenyl)-1-butylamine	604-603-5	147769-93-5	Cease Manufacture	Intermediate	Individual	Cease manufacture	23-03-2015	View substance registered dossier
(S)-6-(2-(7-bromo-9,9-difluoro-9H-fluoren-2-yl)-2-oxoethyl) 5-tert-butyl 5-azaspiro[2.4]heptane-5,6-dicarboxylate	941-125-9	-	Cease Manufacture	Intermediate	Joint	Cease manufacture	09-06-2015	View substance registered dossier
(S)-[2-(phenylmethoxy)propylidene]hydrazinecarboxylate, tert-butyle	439-220-0	-	Cease Manufacture	NONS	Individual	Cease manufacture	10-11-2008	View substance registered dossier
(S)-azetidine-2-carboxylic acid; 4-cyanobenzylamide hydrochloride	433-010-2	-	Cease Manufacture	NONS	Individual	Cease manufacture	10-11-2008	View substance registered dossier
(S)-methyl 5-(4-(benzyloxy)phenyl)-3,4-dihydro-2H-pyrrole-2-carboxylate	815-198-1	934240-38-7	Cease Manufacture	Intermediate	Joint	Cease manufacture	14-03-2018	View substance registered dossier
(S)-tert-butyl 6-(5-(7-bromo-9,9-difluoro-9H-fluoren-2-yl)-1H-imidazol-2-yl)-5-azaspiro[2.4]heptane-5-carboxylate	939-899-8	1441670-89-8	Cease Manufacture	Intermediate	Joint	Cease manufacture	09-06-2015	View substance registered dossier
(S)-tert-butyl(1-((3-fluoro-2-(phenylcarbamoyl)phenyl)amino)-1-oxobutan-2 yl)carbamate	942-159-7	-	Cease Manufacture	Intermediate	Individual	Cease manufacture	20-07-2015	View substance registered dossier
(tert-Butoxycarbonyl)methyl 2-[1-[(4-chlorophenyl)carbonyl]-5-methoxy-2-methylindol-3-yl]acetate	616-210-6	75302-98-6	Cease Manufacture	Intermediate	Individual	Cease manufacture	17-10-2012	View substance registered dossier
(trimethoxysilyl)methyl prop-2-enoate	700-313-9	21134-38-3	Cease Manufacture	Intermediate	Individual	Cease manufacture	18-11-2009	View substance registered dossier
(TRIMETHYLENEDINITRILO)TETRAKISACETONITRILE	429-330-7	-	Cease Manufacture	Intermediate	Individual	Cease manufacture	03-02-2012	View substance registered dossier
(Z)-4-hydroxy-4-(6-methoxynaphthalen-2-yl)but-3-en-2-one	700-075-6	218768-11-7	Cease Manufacture	Intermediate	Individual	Cease manufacture	11-11-2008	View substance registered dossier
(Z)-5-Amino-α-(methoxyimino)-1,2,4-thiadiazole-3-acetic acid	456-150-6	-	Cease Manufacture	NONS	Individual	Cease manufacture	04-03-2011	View substance registered dossier
(Z)-Octadec-9-enylamine, ethoxylated 1 - 4.5 moles ethoxylated	500-048-7	26635-93-8	Cease Manufacture	Full	Joint	Cease manufacture	03-10-2018	View substance registered dossier
(±)-2-(6-methoxy-2-naphthyl)propionic acid	247-485-7	26159-31-9	Cease Manufacture	Intermediate	Joint	Cease manufacture	10-09-2013	View substance registered dossier
(±)-2-aminododecanoic acid	252-454-6	35237-37-7	Cease Manufacture	Intermediate	Individual	Cease manufacture	01-02-2018	View substance registered dossier
(±)-3-hexyl-5,6-dihydro-4-hydroxy-6-undecyl-2H-Pyran-2-one	603-982-4	136890-21-6	Cease Manufacture	Intermediate	Joint	Cease manufacture	03-12-2012	View substance registered dossier
(η-cumene)-(η-cyclopentadienyl)iron(II) trifluoromethane-sulfonate CG 26-751	407-880-9	117549-13-0	Cease Manufacture	NONS	Joint	Cease manufacture	26-11-2010	View substance registered dossier
1,1'-(1,3-phenylenedioxy)bis(3-(2-(prop-2-enyl)phenoxy)propan-2-ol) COMPIMIDE™ 121	405-840-5	110866-35-8	Cease Manufacture	NONS	Individual	Cease manufacture	10-11-2008	View substance registered dossier
1,1'-(4-chlorobutylidene)bis[4-fluorobenzene]	221-998-6	3312-04-7	Cease Manufacture	Full	Joint	Cease manufacture	11-08-2017	View substance registered dossier
1,1'-(tridecylimino)bis-2-propanol	613-099-6	62889-66-1	Cease Manufacture	Intermediate	Individual	Cease manufacture	17-03-2010	View substance registered dossier
1,1'-[methylenebis(oxy)]dibutane	219-909-0	2568-90-3	Cease Manufacture	Intermediate	Individual	Cease manufacture	06-05-2011	View substance registered dossier
1,1'-methylenebis[4-fluorobenzene]	207-274-2	457-68-1	Cease Manufacture	Intermediate	Joint	Cease manufacture	03-11-2010	View substance registered dossier
1,1,1,2,2,3,3,4,4,5,5,6,6-tridecafluorotetradecane	432-570-5	-	Cease Manufacture	NONS	Individual	Cease manufacture	10-11-2008	View substance registered dossier
1,1,1-Tris(p-hydroxyphenyl)ethane, mixed esters with 3-Diazo-3,4-dihydro-4-oxonaphthalene 2-sulphonic acid and 6-Diazo-5,6-dihydro-5-oxonaphthalene 2-sulphonic acid	422-760-6	-	Cease Manufacture	NONS	Individual	Cease manufacture	07-02-2011	View substance registered dossier
1,1,2,2,3,3,4,4,4-nonafluoro-N,N-bis(2-hydroxyethyl)butane-1-sulphonamide	252-044-7	34455-00-0	Cease Manufacture	Full	Joint	Cease manufacture	02-10-2018	View substance registered dossier
1,1,2,2,3,3,4,4,4-nonafluoro-N-methylbutane-1-sulfonamide	614-396-3	68298-12-4	Cease Manufacture	Intermediate	Individual	Cease manufacture	30-03-2021	View substance registered dossier
1,1,2,2-tetramethoxyethane	463-280-7	-	Cease Manufacture	NONS	Individual	Cease manufacture	01-03-2018	View substance registered dossier
1,1-diethoxy-3,7-dimethylocta-2,6-diene	231-323-7	7492-66-2	Cease Manufacture	Full	Joint	Cease manufacture	03-05-2017	View substance registered dossier
1,1-dimethylethyl 4'-(bromomethyl)biphenyl-2-carboxylate	442-850-9	114772-40-6	Cease Manufacture	NONS	Individual	Cease manufacture	10-11-2008	View substance registered dossier
1,12-bis (diisopropyl phosphoryl) dodecane	919-645-2	-	Cease Manufacture	Intermediate	Joint	Cease manufacture	07-10-2015	View substance registered dossier
1,2,3,4-tetrahydroisoquinoline	202-050-0	91-21-4	Cease Manufacture	Intermediate	Joint	Cease manufacture	21-08-2013	View substance registered dossier
1,2,3-triaqua-1,2:1,2:1,3:1,3:2,3:2,3-hexa-μ-acetato-(O,O')-μ3-oxo-triangulo-triiridium acetate IR 112	417-670-9	-	Cease Manufacture	NONS	Individual	Cease manufacture	10-11-2008	View substance registered dossier
1,2,4-Thiadiazole-3-ethanethioic acid, 5-amino-alpha-[(triphenylmethoxy)imino]-, S-2-benzothiazolyl ester, (alphaZ)-	447-420-4	-	Cease Manufacture	NONS	Individual	Cease manufacture	22-02-2013	View substance registered dossier
1,2-Benzenedicarboxylic acid, di-C6-10-alkyl esters	271-094-0	68515-51-5	Cease Manufacture	Full	Joint	Cease manufacture	23-03-2016	View substance registered dossier
1,2-Bis(2-aminophenoxy)ethane	459-990-1	52411-34-4	Cease Manufacture	Full	Individual	Cease manufacture	06-06-2013	View substance registered dossier
1,2-bis(vinylsulfonylacetamido)ethane H-603	404-790-1	66710-66-5	Cease Manufacture	NONS	Individual	Cease manufacture	10-11-2008	View substance registered dossier
1,2-bis[4-fluoro-6-{4-sulfo-5-(2-(4-sulfonaphtalene-3-ylazo)-1-hydroxy-3,6-disulfo-8-aminonaphthalene-7-ylazo)phenylamino}-1,3,5-triazin-2-ylamino]ethane;x-sodium, y-potassium salts x = 7,755 y = 0,245 REACTIVE NAVY DER 7678	417-610-1	155522-09-1	Cease Manufacture	NONS	Individual	Cease manufacture	10-11-2008	View substance registered dossier
1,2-dihydroxyanthraquinone	200-782-5	72-48-0	Cease Manufacture	Full	Joint	Cease manufacture	15-05-2018	View substance registered dossier
1,2-Ethanediamine, N-(5-methoxy-2-nitrophenyl)-, monohydrochloride	415-480-0	86419-69-4	Cease Manufacture	NONS	Joint	Cease manufacture	10-11-2008	View substance registered dossier
1,3,5-Benzenetricarboxylic acid, copper(2+) salt (2:3)	813-272-8	309721-49-1	Cease Manufacture	Full	Joint	Cease manufacture	26-09-2016	View substance registered dossier
1,3,5-triazine-2,4,6-triyltrinitrilohexamethanol	208-503-9	531-18-0	Cease Manufacture	Intermediate	Individual	Cease manufacture	31-10-2012	View substance registered dossier
1,3,5-tris(3,5-dicyclohexyl-4-hydroxybenzyl)perhydro-1,3,5-triazine-2,4,6-trione CG 25-955	404-180-5	-	Cease Manufacture	NONS	Individual	Cease manufacture	10-11-2008	View substance registered dossier
1,3-Benzenedisulfonic acid, 4,4'-[1,2-ethenediylbis[(3-sulfo-4,1-phenylene)imino(6-chloro-1,3,5-triazine-4,2-diyl)imino]]bis[6-[[5-(aminocarbonyl)-1-ethyl-1,6-dihydro-2-hydroxy-4-methyl-6-oxo-3-pyridinyl]azo]-, hexasodium salt	273-662-3	68991-98-0	Cease Manufacture	Full	Joint	Cease manufacture	01-03-2018	View substance registered dossier
1,3-benzodioxolane	205-992-0	274-09-9	Cease Manufacture	Intermediate	Individual	Cease manufacture	22-05-2013	View substance registered dossier
1,3-bis(vinylsulfonylacetamido)propane H-604	428-350-3	93629-90-4	Cease Manufacture	NONS	Individual	Cease manufacture	10-11-2008	View substance registered dossier
1,3-bis[(2-hydroxyethyl)sulfanyl]propan-2-ol	700-829-4	5324-06-1	Cease Manufacture	Intermediate	Individual	Cease manufacture	21-06-2012	View substance registered dossier
1,3-dichloro-2-methoxy-5-nitrobenzene T 1049	403-350-6	17742-69-7	Cease Manufacture	NONS	Individual	Cease manufacture	16-08-2010	View substance registered dossier
1,3-dichloro-4-fluorobenzene 1,3-DICHLOR-4-FLUORBENZOL; B-7	406-160-1	1435-48-9	Cease Manufacture	NONS	Joint	Cease manufacture	10-11-2008	View substance registered dossier
1,3-dihydro-1-oxoisobenzofuran-5-carbonitrile	279-900-2	82104-74-3	Cease Manufacture	Full	Joint	Cease manufacture	17-10-2012	View substance registered dossier
1,3-dihydro-5-methoxy-2H-benzimidazole-2-thione	253-326-2	37052-78-1	Cease Manufacture	Full	Joint	Cease manufacture	06-12-2018	View substance registered dossier
1,3-Dioxan-2-one	423-980-5	-	Cease Manufacture	NONS	Individual	Cease manufacture	10-11-2008	View substance registered dossier
1,3-dioxepane	208-015-6	505-65-7	Cease Manufacture	Full	Joint	Cease manufacture	16-06-2020	View substance registered dossier
1,3-Dioxolane-4-methanol, 2-(2,4-dichlorophenyl)-2-(1H-imidazol-1-ylmethyl)-, 4-methylbenzenesulfonate (ester), (2R,4R)-rel-	603-791-6	134071-44-6	Cease Manufacture	Intermediate	Individual	Cease manufacture	26-01-2015	View substance registered dossier
1,3-disodium, 7-(2-{4-[(4-{2-[2-(cyanoamino)-4,6-dihydroxypyrimidin-5-yl]diazen-1-yl}benzene)amido]-3-methoxyphenyl}diazen-1-yl)naphthalene-1,3-disulfonate	931-147-7	-	Cease Manufacture	Intermediate	Individual	Cease manufacture	08-07-2010	View substance registered dossier
1,4-Benzene disulfonic acid, 2,2'-[1,2-ethenediylbis[(3-sulfo-4 ,1-phenylene)imino[6-(1-methylpropyl)amino]-1,3,5-triazine-4 ,2-diyl]imino]]bis-, hexasodium salt	451-550-7	714252-10-5	Cease Manufacture	NONS	Joint	Cease manufacture	10-11-2008	View substance registered dossier
1,4-Benzenedicarboxylic acid, compd. with 1,6-hexanediamine (1:1)	700-230-8	3160-86-9	Cease Manufacture	Intermediate	Joint	Cease manufacture	23-07-2014	View substance registered dossier
1,4-Benzenedicarboxylic acid, dimethyl ester, manuf. of, by-products from A complex residuum from the distillation of products from the manufacture of dimethyl terephthalate by air oxidation and esterification of p-xylene. It consists of polyphenyl polyesters.	273-521-6	68988-22-7	Cease Manufacture	Full	Joint	Cease manufacture	10-07-2014	View substance registered dossier
1,4-bis(2,3-dihydroxypropylamino)anthraquinone	421-470-7	99788-75-7	Cease Manufacture	NONS	Individual	Cease manufacture	10-11-2008	View substance registered dossier
1,4-bis[(2-methylphenyl)amino]anthraquinone	229-792-8	6737-68-4	Cease Manufacture	Full	Joint	Cease manufacture	12-01-2018	View substance registered dossier
1,4-diamino-2,3-dichloroanthraquinone	201-348-8	81-42-5	Cease Manufacture	Full	Joint	Cease manufacture	24-08-2017	View substance registered dossier
1,4-diamino-2,3-diphenoxyanthraquinone	229-066-0	6408-72-6	Cease Manufacture	Intermediate	Joint	Cease manufacture	25-01-2018	View substance registered dossier
1,4-dibromobutane	203-775-5	110-52-1	Cease Manufacture	Full	Joint	Cease manufacture	19-08-2019	View substance registered dossier
1,4-dichloro-2-(1,1,2,3,3,3-hexafluoropropoxy)-5-nitrobenzene	620-459-6	130841-23-5	Cease Manufacture	Intermediate	Joint	Cease manufacture	04-11-2014	View substance registered dossier
1,4-dichloro-2-(1,1,2,3,3,3-hexafluoropropoxy)benzene	921-909-7	-	Cease Manufacture	Intermediate	Individual	Cease manufacture	24-10-2011	View substance registered dossier
1,4-dichlorobenzene	203-400-5	106-46-7	Cease Manufacture	Intermediate	Joint	Cease manufacture	15-04-2018	View substance registered dossier
1,4-diisobutyl-2,3,5,6-tetrahydroxy-1,4-dioxo-1,4-diphosphorinane CYAGARD RF 1204 (FLAME RETARDANT)	415-160-0	-	Cease Manufacture	NONS	Individual	Cease manufacture	10-11-2008	View substance registered dossier
1,4-naphthoquinone	204-977-6	130-15-4	Cease Manufacture	Intermediate	Joint	Cease manufacture	24-11-2017	View substance registered dossier
1,5,10-Trimethylcyclododeca-1,5,9-triene with 1,5,9-trimethylcyclododeca-1,5,9-triene and 2-methyl-1,3-butadiene homopolymer	931-107-9	-	Cease Manufacture	Intermediate	Individual	Cease manufacture	15-06-2010	View substance registered dossier
1,5-bis(3,4-dimethoxyphenyl)-penta-1,4-dien-3-one 1,4-PENTADIEN-3-ON, 1,5-BIS(3,4-DIMETHOXYPHENYL)-	421-570-0	-	Cease Manufacture	NONS	Individual	Cease manufacture	10-11-2008	View substance registered dossier
1,5-dichloro-2-(1-methylethoxy)-4-nitrobenzene	255-259-4	41200-97-9	Cease Manufacture	Intermediate	Joint	Cease manufacture	27-02-2013	View substance registered dossier
1,6,10-dodecatriene, 7,11-dimethyl-3-methylene-, (6E)-, hydrogenated	942-471-3	-	Cease Manufacture	Full	Individual	Cease manufacture	08-09-2015	View substance registered dossier
1,6,7,8,9,14,15,16,17,17,18,18-dodecachloropentacyclo[12.2.1.16,9.02,13.05,10]octadeca-7,15-diene	236-948-9	13560-89-9	Cease Manufacture	Full	Joint	Cease manufacture	20-10-2020	View substance registered dossier
1,6-bis((dibenzylthiocarbamoyl)disulfanyl)hexane	429-280-6	151900-44-6	Cease Manufacture	Full	Individual	Cease manufacture	29-07-2014	View substance registered dossier
1,6-bis(3,3-bis((1-methylpentylidenimino)propyl)ureido)hexane SETALUX EPC 4690	420-190-2	771478-66-1	Cease Manufacture	NONS	Individual	Cease manufacture	10-11-2008	View substance registered dossier

Showing 1 - 200 of 26,866 results.

Registrant/Supplier	Address	Country	Registration Status	Name	EC / List no.	CAS no.	Last update year	Details
[Confidential]	-	-	-	((2R,3R,4R,5R)-3-(benzoyloxy)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-4-fluoro-4-methyltetrahydrofuran-2-yl)methyl benzoate	807-766-2	863329-65-1	-	View substance registered dossier
Yordas GmbH	Äuβere Nürnberger Straβe 62 91301 Forchheim Germany	Germany	Cease Manufacture	((4S,4aR,7S,7aR)-4,7-dimethylhexahydrocyclopenta[c]pyran-1(3H)-one	953-513-5	-	2023	View substance registered dossier
Sicor - Società Italiana Corticosteroidi S.r.l.	Piazzale Luigi Cadorna 4 20123 Milano (MI) Italy	Italy	Cease Manufacture	(+)-2-amino-1-butanol	227-475-9	5856-62-2	2022	View substance registered dossier
Janssen Pharmaceutica N.V.	Turnhoutseweg 30 2340 Beerse Belgium	Belgium	Cease Manufacture	(+-)-2,4-dihydro-4-[4-[4-(4-methoxyphenyl)-1-piperazinyl]phenyl]-2-(1-methylpropyl)-3H-1,2,4-triazol-3-one	607-685-0	252964-68-4	2021	View substance registered dossier
Janssen Pharmaceutica N.V.	Turnhoutseweg 30 2340 Beerse Belgium	Belgium	Cease Manufacture	(+-)-TRANS-3-METHYL-1-[(4-METHYLPHENYL)SULFONYL]-4-PHENYLPIPERIDINE-4-CARBONITRILE	607-821-9	25858-24-6	2020	View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant UK competent national authority.	-	-	No longer Valid	(+/-) tetrahydrofurfuryl (R)-2-[4-(6-chloroquinoxalin-2-yloxy)phenyloxy]propionate	414-200-4	200509-41-7	2022	View substance registered dossier
ESIM Chemicals GmbH	St.-Peter-Strasse 25 4020 Linz Austria	Austria	Cease Manufacture	(+/-) tetrahydrofurfuryl (R)-2-[4-(6-chloroquinoxalin-2-yloxy)phenyloxy]propionate	414-200-4	200509-41-7	2022	View substance registered dossier
Janssen Pharmaceutica N.V.	Turnhoutseweg 30 2340 Beerse Belgium	Belgium	Cease Manufacture	(+/-)-(R,S)-6-fluoro-3,4-dihydro-2-oxiranyl-2H-1-benzopyran	419-630-6	793669-26-8	2017	View substance registered dossier
Merck KGaA	Frankfurter Strasse 250 64293 Darmstadt Germany	Germany	Cease Manufacture	(+/-)-(R,S)-6-fluoro-3,4-dihydro-2-oxiranyl-2H-1-benzopyran	419-630-6	793669-26-8	2023	View substance registered dossier
Janssen Pharmaceutica N.V.	Turnhoutseweg 30 2340 Beerse Belgium	Belgium	Cease Manufacture	(+/-)-[(R,R)and(R,S)]-6-fluoro-3,4-dihydro-2-oxiranyl-2H-1-benzopyran	419-600-2	99199-90-3	2017	View substance registered dossier
OLON Spa	Strada Rivoltana Km 6/7 20053 RODANO Milano Italy	Italy	Cease Manufacture	(1-chlorocyclohexyl) cyclohexyl ketone	280-893-3	83803-75-2	2022	View substance registered dossier
[Confidential]	-	-	-	(1-ethoxy-1-oxopropan-2-yl) 5-[2-chloro-4-(trifluoromethyl)phenoxy]-2-nitrobenzoate	616-466-9	77501-63-4	-	View substance registered dossier
CHEMICAL INSPECTION & REGULATION SERVICE LIMITED	Regus Harcourt Centre D02 HW77 Dublin Ireland	Ireland	Cease Manufacture	(1-methylethylidene)di-4,1-phenylenetetraphenyl diphosphate	425-220-8	5945-33-5	2014	View substance registered dossier
OLON Spa	Strada Rivoltana Km 6/7 20053 RODANO Milano Italy	Italy	Cease Manufacture	(10aS)-methyl 10a-methoxy-7-methyl-4,6,6a,7,8,9,10,10a-octahydroindolo[4,3-fg]quinoline-9-carboxylate	607-239-5	23495-64-9	2022	View substance registered dossier
[Confidential]	-	-	-	(10S)-10,11-Dihydro-10-hydroxy-5H-dibenz[b,f]azepine-5-carboxamide	810-248-9	104746-04-5	-	View substance registered dossier
Bayer AG	Kaiser-Wilhelm-Allee 1 51373 Leverkusen Germany	Germany	Cease Manufacture	(17α)-17-hydroxy-3-oxoandrost-4-ene-17-carbonitrile	278-780-9	77881-13-1	2022	View substance registered dossier
Minakem Dunkerque Production	224 avenue de la Dordogne Zone d'entreprises du Nord Gracht 59640 DUNKERQUE France	France	Cease Manufacture	(1E)-N-hydroxy-1-(naphthalen-1-yl)ethanimine	700-765-7	100485-51-6	2019	View substance registered dossier
ROQUETTE Frères	1 rue de la haute loge 62136 LESTREM Cedex France	France	Cease Manufacture	(1R)-1-[(4R,4aR,8aS)-2,6-bis(3,4-dimethylphenyl)tetrahydro[1,3]dioxino[5,4-d][1,3]dioxin-4-yl]ethane-1,2-diol	413-110-2	1171816-77-5	2018	View substance registered dossier
REACH COMPLIANCE SERVICES LIMITED	Suite 1E, Paramount Court, Corrig Road, Sandyford Dublin 18 Dublin Ireland	Ireland	Cease Manufacture	(1R)-1-[(4R,4aR,8aS)-2,6-bis(3,4-dimethylphenyl)tetrahydro[1,3]dioxino[5,4-d][1,3]dioxin-4-yl]ethane-1,2-diol	413-110-2	1171816-77-5	2021	View substance registered dossier
REACH24H CONSULTING GROUP	Suite 1E, Paramount Court, Corrig Road, Sandyford Dublin 18 Dublin Ireland	Ireland	Cease Manufacture	(1R)-1-[(4R,4aR,8aS)-2,6-bis(3,4-dimethylphenyl)tetrahydro[1,3]dioxino[5,4-d][1,3]dioxin-4-yl]ethane-1,2-diol	413-110-2	1171816-77-5	2021	View substance registered dossier
Janssen Pharmaceutica N.V.	Turnhoutseweg 30 2340 Beerse Belgium	Belgium	Cease Manufacture	(1R,12R)-9-methoxy-4-methyl-11-oxa-4-azatetracyclo[8.6.1.0^{1,12}.0^{6,17}]heptadeca-6(17),7,9,15-tetraen-14-one	428-690-2	1668-86-6	2019	View substance registered dossier
Aspen Oss BV	Kloosterstraat 6 5349 AB Oss Netherlands	Netherlands	Cease Manufacture	(1R,2S,10R,11S,15S)-2,15-dimethyl-4-(morpholin-4-yl)-13-(pyrrolidin-1-yl)tetracyclo[8.7.0.0²,⁷.0¹¹,¹⁵]heptadecane-5,14-diol	601-595-5	119302-20-4	2022	View substance registered dossier
Janssen Pharmaceutica N.V.	Turnhoutseweg 30 2340 Beerse Belgium	Belgium	Cease Manufacture	(1R,2S,3S,4R)-3-((2-chloro-5-fluoropyrimidin-4-yl)amino)bicyclo[2.2.2]octane-2-carboxylic acid	821-184-6	1777721-60-4	2022	View substance registered dossier
Janssen Pharmaceutica N.V.	Turnhoutseweg 30 2340 Beerse Belgium	Belgium	Cease Manufacture	(1R,2S,3S,4R)-3-((5-fluoro-2-(5-fluoro-1-tosyl-1H-pyrrolo[2,3-b]pyridin-3-yl)pyrimidin-4-yl)amino)bicyclo[2.2.2]octane-2-carboxylic acid	821-185-1	1777721-63-7	2022	View substance registered dossier
Evonik Operations GmbH	Rellinghauser Straße 1-11 45128 Essen Germany	Germany	Cease Manufacture	(1R,2S,5R)-2-Isopropyl-5-methylcyclohexyl (2R,5R)-5-hydroxy-1,3-oxathiolane-2-carboxylate	604-569-1	147126-62-3	2021	View substance registered dossier
HH Compliance Ltd	Rubicon Building CIT Campus T12 Y275 Bishopstown Cork Ireland	Ireland	Cease Manufacture	(1R,2S,8S,10S,11S,13R,14R,15S,17S)-1,8-difluoro- 14,17dihydroxy-2,13,15-trimethyl-5-oxotetracyclo[8.7.0.0^{2,7}.0^{11,15}]heptadeca-3,6-diene-14-carbothioic S-acid	617-081-9	80473-92-3	2023	View substance registered dossier
N.V. Ajinomoto OmniChem S.A.	Cooppallaan 91 9230 Wetteren Oost-Vlaanderen Belgium	Belgium	Cease Manufacture	(1R,3R,4S,5R)-methyl 3-acetoxy-4-hydroxy-5-(tosyloxy)cyclohexanecarboxylate	813-307-7	1104200-22-7	2020	View substance registered dossier
N.V. Ajinomoto OmniChem S.A.	Cooppallaan 91 9230 Wetteren Oost-Vlaanderen Belgium	Belgium	Cease Manufacture	(1R,3S,5S)-8-benzyl-8-azabicyclo[3.2.1]octan-3-amine fumarate	943-085-8	-	2021	View substance registered dossier
Cheminova A/S	Thyborønvej 78 DK-7673 Harboøre Denmark	Denmark	Cease Manufacture	(1R,4R,5S)-6,6-dimethyl-4-(tribromomethyl)-3-oxabicyclo[3.1.0]hexan-2-one	619-738-5	87305-03-1	2014	View substance registered dossier
[Confidential]	-	-	-	(1R,4S,4aS,8aR)-9-(dichloromethylene)-1,4,4a,8a-tetrahydro-1,4-methanonaphthalene-5,8-dione	807-377-8	1263184-85-5	-	View substance registered dossier
Minakem Dunkerque Production	224 avenue de la Dordogne Zone d'entreprises du Nord Gracht 59640 DUNKERQUE France	France	Cease Manufacture	(1R,7S)-10,10-Dimethyl-3-thia-4-azatricyclo[5.2.1.0(1,5)]dec-4-ene 3,3-dioxide	621-464-6	107869-45-4	2019	View substance registered dossier
Bidachem S.p.A.	S.S. 11 Padana Superiore No. 8 24040 Fornovo San Giovanni BG Italy	Italy	Cease Manufacture	(1S)-1-cyclopropylethanamine; (2R)-2-hydroxy-2-phenyl-acetic acid	946-290-0	2246580-61-8	2022	View substance registered dossier
Boehringer Ingelheim Pharma GmbH & Co. KG	Binger Strasse 173 55216 Ingelheim am Rhein Germany	Germany	Cease Manufacture	(1S)-1-cyclopropylethanamine; (2R)-2-hydroxy-2-phenyl-acetic acid	946-290-0	2246580-61-8	2022	View substance registered dossier
Janssen Pharmaceutica N.V.	Turnhoutseweg 30 2340 Beerse Belgium	Belgium	Cease Manufacture	(1S)-2,3,4,6-TETRA-O-ACETYL-1,5-ANHYDRO-1-(3-{[5-(4-FLUOROPHENYL)THIOPHEN-2-YL]METHYL}-4-METHYLPHENYL)-D-GLUCITOL	617-901-5	866607-35-4	2022	View substance registered dossier
N.V. Ajinomoto OmniChem S.A.	Cooppallaan 91 9230 Wetteren Oost-Vlaanderen Belgium	Belgium	Cease Manufacture	(1S)-2,3,4,6-TETRA-O-ACETYL-1,5-ANHYDRO-1-(3-{[5-(4-FLUOROPHENYL)THIOPHEN-2-YL]METHYL}-4-METHYLPHENYL)-D-GLUCITOL	617-901-5	866607-35-4	2019	View substance registered dossier
N.V. Ajinomoto OmniChem S.A.	Cooppallaan 91 9230 Wetteren Oost-Vlaanderen Belgium	Belgium	Cease Manufacture	(1S,2R)-1-((2R,3R,4S,6S)-3-acetamido-4-(diallylamino)-6-hydroxy-6-(methoxycarbonyl)tetrahydro-2H-pyran-2-yl)propane-1,2,3-triyl triacetate	700-779-3	-	2020	View substance registered dossier
N.V. Ajinomoto OmniChem S.A.	Cooppallaan 91 9230 Wetteren Oost-Vlaanderen Belgium	Belgium	Cease Manufacture	(1S,3R,4R,5R)-methyl 3-acetoxy-4,5-dihydroxycyclohexanecarboxylate	839-204-7	1104200-21-6	2020	View substance registered dossier
N.V. Ajinomoto OmniChem S.A.	Cooppallaan 91 9230 Wetteren Oost-Vlaanderen Belgium	Belgium	Cease Manufacture	(1S,3R,4R,5S)-methyl 3-acetoxy-5-azido-4-(((2S,3S,4R,5R,6S)-3,4,5-tris(benzyloxy)-6-methyltetrahydro-2H-pyran-2-yl)oxy)cyclohexanecarboxylate	813-345-4	1104200-23-8	2020	View substance registered dossier
Productos Esteve Internacional, S.A	Avd. Verge Montserrat, 12. 08024 Barcelona Barcelona Spain	Spain	Cease Manufacture	(2,2,8-trimethyl-4H-[1,3]dioxino[4,5-c]pyridin-5-yl)methanol hydrochloride	700-391-4	6953-28-2	2017	View substance registered dossier
Stewardship Chemicals 40	Długosza 67 43-188 Orzesze Poland	Poland	Cease Manufacture	(2,4-Difluorophenyl)(4-Fluorophenyl)methanone	813-638-7	80512-44-3	2023	View substance registered dossier
WeylChem Lamotte S.A.S	Rue du Flottage B.P. 1 60350 Trosly Breuil France	France	Cease Manufacture	(2,5-dimethylphenyl)-acetyl chloride	470-780-9	-	2019	View substance registered dossier
BASF SE	Carl-Bosch-Str. 38 67056 Ludwigshafen am Rhein Rheinland-Pfalz Germany	Germany	Cease Manufacture	(2-hydroxyethyl)(3-hydroxypropyl)dimethylammonium chloride	278-860-3	78182-00-0	2020	View substance registered dossier
Dynamit Nobel GmbH Explosivstoff- und Systemtechnik	Kalkstrasse 218 51377 Leverkusen Germany	Germany	Cease Manufacture	(2R)-2-(2,4-difluorophenyl)-1,1-difluoro-1-{5-[4-(2,2,2-trifluoroethoxy)phenyl]pyridin-2-yl}-3-(1H-tetrazol-1-yl)propan-2-ol	841-499-2	1340593-59-0	2022	View substance registered dossier
[Confidential]	-	-	-	(2R,3R,4R,5R)-5-(4-benzamido-2-oxopyrimidin-1(2H)-yl)-2-(benzoyloxymethyl)-4-fluoro-4-methyltetrahydrofuran-3-yl benzoate	807-677-9	817204-32-3	-	View substance registered dossier
N.V. Ajinomoto OmniChem S.A.	Cooppallaan 91 9230 Wetteren Oost-Vlaanderen Belgium	Belgium	Cease Manufacture	(2R,3R,4S,5R)-2-(acetoxymethyl)-6-oxotetrahydro-2H-pyran-3,4,5-triyl triacetate	612-107-5	61259-48-1	2019	View substance registered dossier
TAMARANG, S.A.	Balmes, 84, 4-2 08008 Barcelona Barcelona Spain	Spain	Cease Manufacture	(2S)-2-[[(2S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl]amino]propanoic acid	406-310-6	-	2012	View substance registered dossier
MITSUBISHI GAS CHEMICAL EUROPE GMBH	Immermannstr.13 40210 Duesseldorf Germany	Germany	Cease Manufacture	(2S)-2-Aminobutyramide Hydrochloride	471-490-5	7682-20-4	2013	View substance registered dossier
OLON Spa	Strada Rivoltana Km 6/7 20053 RODANO Milano Italy	Italy	Cease Manufacture	(2S)-2-{[(1E)-(5-chloro-2-hydroxyphenyl)(phenyl)methylene]amino}-3-methylbutanoic acid	609-516-6	38075-43-3	2022	View substance registered dossier
Avara Shannon Pharmaceutical Services Limited	Shannon Industrial Estate V14 FX09 Shannon Clare Ireland	Ireland	Cease Manufacture	(2S)-5-methoxy-N-propyl-1,2,3,4-tetrahydronaphthalen-2-amine hydrochloride (1:1)	695-797-0	93601-86-6	2021	View substance registered dossier
Avara Shannon Pharmaceutical Services Limited	Shannon Industrial Estate V14 FX09 Shannon Clare Ireland	Ireland	Cease Manufacture	(2S)-5-methoxy-N-propyl-1,2,3,4-tetrahydronaphthalen-2-aminium (2R)-(2-chlorophenyl)(hydroxy)acetate	814-350-4	1352917-66-8	2021	View substance registered dossier
Janssen Pharmaceutica N.V.	Turnhoutseweg 30 2340 Beerse Belgium	Belgium	Cease Manufacture	(2S)-{[(benzyloxy)carbonyl]amino}(cyclohexyl)acetic acid	478-210-0	69901-75-3	2019	View substance registered dossier
N.V. Ajinomoto OmniChem S.A.	Cooppallaan 91 9230 Wetteren Oost-Vlaanderen Belgium	Belgium	Cease Manufacture	(2S,3R,4R,5S,6R)-3,4,5-tris(benzyloxy)-2-methyl-6-(p-tolylthio)tetrahydro-2H-pyran	835-228-7	211801-54-6	2021	View substance registered dossier
N.V. Ajinomoto OmniChem S.A.	Cooppallaan 91 9230 Wetteren Oost-Vlaanderen Belgium	Belgium	Cease Manufacture	(2S,3R,4S,5R,6R)-6-(acetoxymethyl)-2-(3-((5-(4-fluorophenyl)thiophen-2-yl)methyl)-4-methylphenyl)-2-hydroxytetrahydro-2H-pyran-3,4,5-triyl triacetate	921-285-6	1071929-02-6	2019	View substance registered dossier
Warsaw University of Technology, Faculty of Chemistry, Laboratory of Technological Processes	Noakowskiego 3 00-664 Warszawa Poland	Poland	Cease Manufacture	(2S,3S)-2,3-Bis((4-methoxybenzoyl)oxy)succinic acid	606-247-6	191605-10-4	2014	View substance registered dossier
Janssen Pharmaceutica N.V.	Turnhoutseweg 30 2340 Beerse Belgium	Belgium	Cease Manufacture	(2S,3S)-3-amino-N-cyclopropyl-2-hydroxyhexanamide hydrochloride	478-270-8	-	2019	View substance registered dossier
F.I.S. Fabbrica Italiana Sintetici S.p.a.	Viale Milano, 26 36075 Montecchio Maggiore (VI) Veneto Italy	Italy	Cease Manufacture	(2S,3S,5R)-2-hexyl-3-hydroxy-5-(phenylmethoxy)-Hexadecanoic acid compd. with (S)-α-methylbenzenemethanamine (1:1)	604-018-5	137433-01-3	2015	View substance registered dossier
Patheon Austria GmbH & Co KG	St. Peter Strasse 25 4020 Linz Austria	Austria	Cease Manufacture	(2S,3S,5R)-2-hexyl-3-hydroxy-5-(phenylmethoxy)-Hexadecanoic acid compd. with (S)-α-methylbenzenemethanamine (1:1)	604-018-5	137433-01-3	2020	View substance registered dossier
Global Product Compliance (Europe) AB	IDEON, Beta 5, Scheelevägen 17 22363 Lund Sweden	Sweden	Cease Manufacture	(2α,4aα,8β)-hexahydro-1,1,5,5-tetramethyl-2H-2,4a-methanonaphthalen-8(5H)-one	249-648-8	29461-13-0	2020	View substance registered dossier
Aspen Oss BV	Kloosterstraat 6 5349 AB Oss Netherlands	Netherlands	Cease Manufacture	(3 β, 5 α, 6β)-3-(acetyloxy)-5-bromo-6-hydroxy-androstan-17-one	419-790-7	4229-69-0	2019	View substance registered dossier
Saltigo GmbH	HSEQ-RA Kaiser-Wilhelm-Allee 40 51373 Leverkusen Germany	Germany	Cease Manufacture	(3,4-Dimethoxy-bicyclo[4.2.0]octa-1,3,5-trien-7-yl)-methylamine	917-818-7	73344-75-9	2013	View substance registered dossier
Boehringer Ingelheim Pharma GmbH & Co. KG	Binger Strasse 173 55216 Ingelheim am Rhein Germany	Germany	Cease Manufacture	(3-aminophenyl)pyridin-3-ylmethanone	428-230-0	79568-06-2	2015	View substance registered dossier
Global Product Compliance (Europe) AB	IDEON, Beta 5, Scheelevägen 17 22363 Lund Sweden	Sweden	Cease Manufacture	(3-aminophenyl)urea	247-201-1	25711-72-2	2022	View substance registered dossier
Global Product Compliance (Europe) AB	IDEON, Beta 5, Scheelevägen 17 22363 Lund Sweden	Sweden	Cease Manufacture	(3-aminophenyl)uronium chloride	261-858-1	59690-88-9	2022	View substance registered dossier
N.V. Ajinomoto OmniChem S.A.	Cooppallaan 91 9230 Wetteren Oost-Vlaanderen Belgium	Belgium	Cease Manufacture	(3-endo)-8-methyl-8-azabicyclo[3.2.1]oct-3-yl methanesulfonate	700-367-3	35130-97-3	2012	View substance registered dossier
N.V. Ajinomoto OmniChem S.A.	Cooppallaan 91 9230 Wetteren Oost-Vlaanderen Belgium	Belgium	Cease Manufacture	(3aS,4R,5S,6S,8R,9R,9aR,10R)-6-ethenyl-5-hydroxy-4,6,9,10-tetramethyl-1-oxodecahydro-3a,9-propanocyclopenta[8]annulen-8-yl[(methylsulfonyl)oxy]acetate	700-396-1	60924-38-1	2012	View substance registered dossier
Janssen Pharmaceutica N.V.	Turnhoutseweg 30 2340 Beerse Belgium	Belgium	Cease Manufacture	(3beta)-17-(3-pyridinyl)androsta-5,16-dien-3-yl acetate compound with (2R,3R)-tartaric acid and methanol (1 : 1 : 1.5)	931-336-4	-	2019	View substance registered dossier
Agfa-Gevaert N.V.	Septestraat 27 2640 Mortsel Belgium	Belgium	Cease Manufacture	(3E)-2-chloro-3-(hydroxymethylene)cyclohexene-1-carbaldehyde	801-656-8	1416808-92-8	2021	View substance registered dossier
Esteve Quimica, S.A.	Torre Esteve Passeig de la Zona Franca, 109, 4ª Planta 08038 Barcelona Barcelona Spain	Spain	Cease Manufacture	(3R)-3-(2-amino-2-oxoethyl)-5-methylhexanoic acid	605-923-8	181289-33-8	2017	View substance registered dossier
[Confidential]	-	-	-	(3R,4R,5R,6R,9R,10Z,11R,12S,14S)-6-{[(2S,3R,4S,6R)-4-(dimethylamino)-3-hydroxy-6-methyltetrahydro-2H-pyran-2-yl]oxy}-14-ethyl-7,12,13-trihydroxy-4-{[(2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyltetrahydro-2H-pyran-2-yl]oxy}-3,5,7,9,11,13-hexamethyloxacyclotetradecane-2,10-dione 10-oxime	603-883-6	134931-01-4	-	View substance registered dossier
Hovione FarmaCiencia SA	Sete Casas 2674-506 Loures Portugal	Portugal	Cease Manufacture	(3R,4S,5S,6R,7R,9R,10E,11S,12R,13S,14R)-6-[(2S,3R,4S,6R)-4-dimethylamino-3-hydroxy-6-methyloxan-2-yl]oxy-14-ethyl-7,12,13-trihydroxy-10-hydroxyimino-4-[(2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyloxan-2-yl]oxy-3,5,7,9,11,13-hexamethyl-1-oxacyclotetradecan-2-one	603-467-4	13127-18-9	2017	View substance registered dossier
MINAKEM Beuvry Production SAS	145, Chemin des Lilas 59310 Beuvry-la-Forêt France	France	Cease Manufacture	(3R,7aR)-3-tert-butyl-1,5-dioxodihydro-1H-pyrrolo[1,2-c][1,3]oxazole-7a(5H)-carbaldehyde	812-036-1	1214741-19-1	2019	View substance registered dossier
MINAKEM Beuvry Production SAS	145, Chemin des Lilas 59310 Beuvry-la-Forêt France	France	Cease Manufacture	(3R,7aR)-3-tert-butyl-7a-{methoxy[(trimethylsilyl)oxy]methyl}dihydro-1H-pyrrolo[1,2-c][1,3]oxazole-1,5(6H)-dione	942-823-6	-	2019	View substance registered dossier
MINAKEM Beuvry Production SAS	145, Chemin des Lilas 59310 Beuvry-la-Forêt France	France	Cease Manufacture	(3R,7aS)-3-tert-butyldihydro-1H-pyrrolo[1,2-c]oxazole-1,5(6H)-dione	810-392-2	171284-84-7	2019	View substance registered dossier
Roche Ireland Limited	Clarehill . Clarecastle Ireland	Ireland	Cease Manufacture	(3S,4aS,8aS)-2-[(2R,3S)-3-amino-2-hydroxy-4-phenylbutyl]-N-tert-butyldecahydroisoquinoline-3-carboxamide	430-230-0	136522-17-3	2020	View substance registered dossier
Roche Ireland Limited	Clarehill . Clarecastle Ireland	Ireland	Cease Manufacture	(3S,4aS,8aS)-N-tert-Butyldecahydro-3-isoquinolinecarboxamide	420-380-5	136465-81-1	2020	View substance registered dossier
CU Chemie Uetikon GmbH	Raiffeisenstrasse 4 77933 Lahr Germany	Germany	Cease Manufacture	(3S,5R,8aS)-3-phenyl-3,5,6,7,8,8a-hexahydro-2H-oxazolo[3,2-a]pyridine-5-carbonitrile	634-598-5	106565-71-3	2020	View substance registered dossier
Lek Pharmaceuticals d.d.	Verovskova 57 1526 Ljubljana Slovenia	Slovenia	Cease Manufacture	(3S,6R,7E,9R,10R,12R,14S,15E,17E,19E,21S,23S,26R,27R,34aS)-9,10,12,13,14,21,22,23,24,25,26,27,32,33,34,34a-hexadecahydro-9,27-dihydroxy-3-[(1R)-2-[(1S,3R,4R)-4-hydroxy-3-methoxycyclohexyl]-1-methylethyl]-10,21-dimethoxy-6,8,12,14,20,26-hexamethyl-23,27-epoxy-3H-pyrido[2,1-c][1,4]-oxaazacyclohentriacontine-1,5,11,28,29(4H,6H,31H)-pentone	610-965-5	53123-88-9	2017	View substance registered dossier
Santrol Europe ApS	Aagade 103 Pjedsted 7000 Fredericia Denmark	Denmark	Cease Manufacture	(3S-cis)-3,6-dimethyl-1,4-dioxane-2,5-dione	224-832-0	4511-42-6	2016	View substance registered dossier
Global Product Compliance (Europe) AB	IDEON, Beta 5, Scheelevägen 17 22363 Lund Sweden	Sweden	Cease Manufacture	(4-(4-aminophenyl)(4-iminocyclohexa-2,5-dienylidene)methyl)-2-methylaniline hydrochloride	211-189-6	632-99-5	2023	View substance registered dossier
Evonik Operations GmbH	Rellinghauser Straße 1-11 45128 Essen Germany	Germany	Cease Manufacture	(4-benzylpiperazin-1-yl)(cyclopropyl)methanone hydrochloride	816-907-7	1294454-93-5	2021	View substance registered dossier
Derivados Quimicos SAU	Strada Rivoltana km6/7 20053 Rodano (Milano) Lombardia Spain	Spain	Cease Manufacture	(4-Chloro-2-fluoro-phenyl)-acetonitrile	642-783-7	75279-53-7	2020	View substance registered dossier
Bidachem S.p.A.	S.S. 11 Padana Superiore No. 8 24040 Fornovo San Giovanni BG Italy	Italy	Cease Manufacture	(4-cyclopropyl-6-methyl-pyrimidin-5-yl)boronic acid	826-639-2	1817776-86-5	2022	View substance registered dossier
Boehringer Ingelheim Pharma GmbH & Co. KG	Binger Strasse 173 55216 Ingelheim am Rhein Germany	Germany	Cease Manufacture	(4-cyclopropyl-6-methyl-pyrimidin-5-yl)boronic acid	826-639-2	1817776-86-5	2022	View substance registered dossier
INTEROR	49, rue d'Ostende F-62100 CALAIS France	France	Cease Manufacture	(4-ethoxyphenyl)(3-(4-fluoro-3-phenoxyphenyl)propyl)dimethylsilane	405-020-7	105024-66-6	2022	View substance registered dossier
Bayer AG	Kaiser-Wilhelm-Allee 1 51373 Leverkusen Germany	Germany	Cease Manufacture	(4-ethoxyphenyl)(3-(4-fluoro-3-phenoxyphenyl)propyl)dimethylsilane	405-020-7	105024-66-6	2010	View substance registered dossier
-	-	-	-	(4R)-Tetrahydro-4-hydroxy-4-methyl-2H-Pyran-2-one	433-160-9	-	-	View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant German competent national authority.	-	-	No longer Valid	(4S,5S)-5-hydroxy-2-methyl-3,4,5,6-tetrahydropyrimidine-4-carboxylic acid	442-870-8	-	2022	View substance registered dossier
-	-	-	-	(4S,5S)-5-hydroxy-2-methyl-3,4,5,6-tetrahydropyrimidine-4-carboxylic acid	442-870-8	-	-	View substance registered dossier
ESIM Chemicals GmbH	St.-Peter-Strasse 25 4020 Linz Austria	Austria	Cease Manufacture	(4Z)-3-methyl-N-nitro-5-{[2-(phenylsulfanyl)-1,3-thiazol-5-yl]methyl}-1,3,5-oxadiazinan-4-imine	427-600-9	192439-46-6	2022	View substance registered dossier
Novartis Ringaskiddy Limited	. . Ringaskiddy County Cork Ireland	Ireland	Cease Manufacture	(5,6-Dimethyl-9-oxo-9H-xanthen-4-yl)acetic acid	700-141-4	117570-53-3	2015	View substance registered dossier
Aspen Oss BV	Kloosterstraat 6 5349 AB Oss Netherlands	Netherlands	Cease Manufacture	(5α)-Androsta-2,16-dien-17-yl acetate	610-545-1	50588-42-6	2019	View substance registered dossier
HH Compliance Ltd	Rubicon Building CIT Campus T12 Y275 Bishopstown Cork Ireland	Ireland	Cease Manufacture	(6ALPHA,11BETA,16ALPHA,17ALPHA)-6,9-DIFLUORO-11-HYDRO XY-16-METHYL-3-OXO-17- (1-OXOPROPOXY)ANDROSTA-1,4-DIENE-CARBOTHIOIC ACID	617-084-5	80474-45-9	2023	View substance registered dossier
Corden Pharma Latina S.p.A.	Via Murillo, 7 IT04013 Sermoneta (LT) Lazio Italy	Italy	Cease Manufacture	(6R,7R)-3-[(5-amino-4-{[(2-aminoethyl)carbamoyl]amino}-1-methyl-1H-pyrazol-2-ium-2-yl)methyl]-7-{[(2Z)-2-(5-amino-1,2,4-thiadiazol-3-yl)-2-{[(2-carboxypropan-2-yl)oxy]imino}acetyl]amino}-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate trifluoroacetate (1:3)	939-998-6	-	2017	View substance registered dossier
Sandoz GmbH	Biochemiestr. 10 6250 Kundl Austria	Austria	Cease Manufacture	(6R,7R)-3-[[(Aminocarbonyl)oxy]methyl]-7-[[(2Z)-2-furanyl(methoxyimino)acetyl]amino]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-en-2-carboxylic acid, 1-butylammonium salt	439-350-8	-	2021	View substance registered dossier
Sandoz GmbH	Biochemiestr. 10 6250 Kundl Austria	Austria	Cease Manufacture	(6R,7R)-7-[[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-methoxyiminoacetyl]amino]-3-(furan-2-carbonylsulfanylmethyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid;hydrochloride	600-507-2	103980-44-5	2021	View substance registered dossier
Sandoz GmbH	Biochemiestr. 10 6250 Kundl Austria	Austria	Cease Manufacture	(6R,7R)-7-amino-3-(5H-imidazo[1,2-b]pyridazin-1-ylmethyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid;hydroiodide	606-382-0	197897-11-3	2021	View substance registered dossier
Sandoz GmbH	Biochemiestr. 10 6250 Kundl Austria	Austria	Cease Manufacture	(6R,7R)-7-amino-3-{[(furan-2-ylcarbonyl)sulfanyl]methyl}-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid	617-065-1	80370-59-8	2021	View substance registered dossier
Sandoz GmbH	Biochemiestr. 10 6250 Kundl Austria	Austria	Cease Manufacture	(6R,7R)-7-{[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetyl]amino}-3-({[5-(carboxymethyl)-4-methyl-1,3-thiazol-2-yl]sulfanyl}methyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid	700-301-3	69739-16-8	2021	View substance registered dossier
Sandoz GmbH	Biochemiestr. 10 6250 Kundl Austria	Austria	Cease Manufacture	(6R-trans)-1-((7-Ammonio-2-carboxylato-8-oxo-5-thia-1-azabicyclo-(4.2.0)oct-2-en-3-yl)methyl)pyridinium iodide	423-260-0	100988-63-4	2021	View substance registered dossier
Sandoz GmbH	Biochemiestr. 10 6250 Kundl Austria	Austria	Cease Manufacture	(6R-trans)-7-amino-3-[[[5-(carboxymethyl)-4-methyl-2-thiazolyl]thio]methyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid	619-847-8	111298-82-9	2021	View substance registered dossier
Sandoz GmbH	Biochemiestr. 10 6250 Kundl Austria	Austria	Cease Manufacture	(6R-trans)-7-amino-8-oxo-3-[[(1,2,5,6-tetrahydro-2-methyl-5,6-dioxo-1,2,4-triazin-3-yl)thio]methyl]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid	261-491-7	58909-56-1	2020	View substance registered dossier
Sandoz GmbH	Biochemiestr. 10 6250 Kundl Austria	Austria	Cease Manufacture	(6S,7S)-7-Amino-3-(methoxymethyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid	435-680-1	-	2021	View substance registered dossier
[Confidential]	-	-	-	(6S,9R,10S,11S,13S,16R,17R)-6,9-difluoro-11,17-dihydroxy-10,13,16-trimethyl-3-oxo-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthrene-17-carboxylic acid	434-320-0	-	-	View substance registered dossier
HH Compliance Ltd	Rubicon Building CIT Campus T12 Y275 Bishopstown Cork Ireland	Ireland	Cease Manufacture	(6S,9R,10S,11S,13S,16R,17R)-6,9-difluoro-11,17-dihydroxy-10,13,16-trimethyl-3-oxo-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthrene-17-carboxylic acid	434-320-0	-	2023	View substance registered dossier
Centrient Pharmaceuticals Netherlands B.V.	Alexander Fleminglaan 1 2613 AX Delft Netherlands	Netherlands	Cease Manufacture	(7R)-7-(4-carboxybutanamido)cephalosporanate amidohydrolase (enzyme substance)	611-406-8	56645-46-6	2022	View substance registered dossier
Aspen Oss BV	Kloosterstraat 6 5349 AB Oss Netherlands	Netherlands	Cease Manufacture	(8R,9S,10R,13S,14S,17R)-17-ethynyl-17-hydroxy-13-methyl-1,2,8,9,10,11,12,14,15,16-decahydrocyclopenta[a]phenanthren-3-one	608-630-3	31528-46-8	2022	View substance registered dossier
Archroma Italy, S.r.l. - OR	Via Manzoni 37 20030 Palazzolo Milanese Italy	Italy	Cease Manufacture	(Benzyloxycarbonyl)methyl 3-[5-acetamido-4-(2-chloro-4,6-dinitrophenylazo)-2-methoxyanilino]propionate	436-000-6	159010-67-0	2017	View substance registered dossier
Archroma Italy, S.r.l. - OR	Via Manzoni 37 20030 Palazzolo Milanese Italy	Italy	Cease Manufacture	(Benzyloxycarbonyl)methyl 4-(1-Butyl-5-cyano-1,6-dihydro-2-hydroxy-4-methyl-6-oxo-3-pyridylazo)-benzoate	442-520-4	-	2017	View substance registered dossier
MINAKEM Beuvry Production SAS	145, Chemin des Lilas 59310 Beuvry-la-Forêt France	France	Cease Manufacture	(Bromomethyl)cyclobutane	700-027-4	17247-58-4	2015	View substance registered dossier
Evonik Operations GmbH	Rellinghauser Straße 1-11 45128 Essen Germany	Germany	Cease Manufacture	(Bromomethyl)cyclobutane	700-027-4	17247-58-4	2018	View substance registered dossier
BASF Lampertheim GmbH	Chemiestrasse 22 68619 Lampertheim Germany	Germany	Cease Manufacture	(C12-C14)tert-alkylammonium methylphosphonate	404-750-3	119415-07-5	2018	View substance registered dossier
[Confidential]	-	-	-	(chloromethyl)bis(4-fluorophenyl)methylsilane	401-200-4	85491-26-5	-	View substance registered dossier
TAKASAGO TEPL-OR(1)	12 rue Torricelli 75017 Paris France	France	Cease Manufacture	(cyclohex-3-en-1-yl)methyl 2-hydroxypropanoate	946-283-2	1864727-96-7	2023	View substance registered dossier
BASF SE	Carl-Bosch-Str. 38 67056 Ludwigshafen am Rhein Rheinland-Pfalz Germany	Germany	Cease Manufacture	(E)-1,4-dibromobut-2-ene	212-472-7	821-06-7	2016	View substance registered dossier
Siegfried St. Vulbas SAS	530, allée de la Luye 01150 SAINT VULBAS France	France	Cease Manufacture	(E)-1,4-dibromobut-2-ene	212-472-7	821-06-7	2017	View substance registered dossier
Novartis Integrated Services Limited	Ringaskiddy P43 FR63 Ringaskiddy Co. Cork Ireland	Ireland	Cease Manufacture	(E)-1,4-dibromobut-2-ene	212-472-7	821-06-7	2015	View substance registered dossier
Contract Chemicals Ltd	Penrhyn Road Knowsley Business Park L34 9HY Prescot Merseyside United Kingdom	United Kingdom	No longer Valid	(E)-1,4-dibromobut-2-ene	212-472-7	821-06-7	2021	View substance registered dossier
BASF Schwarzheide GmbH	Schipkauer Str. 1 01987 Schwarzheide Brandenburg Germany	Germany	Cease Manufacture	(E)-3-(2-chlorophenyl)-2-(4-fluorophenyl)propenal	410-980-5	112704-51-5	2018	View substance registered dossier
Bayer AG	Kaiser-Wilhelm-Allee 1 51373 Leverkusen Germany	Germany	Cease Manufacture	(E)-5-benzyl-1-(2-chloro-1,3-thiazol-5-ylmethyl)-3-methyl-N-nitro-1,3,5-triazinan-2-imine	606-753-7	213967-55-6	2023	View substance registered dossier
Patheon Austria GmbH & Co KG	St. Peterstrasse 25 A-4020 Linz Austria	Austria	Cease Manufacture	(E)-methyl 2-acetyloct-2-enoate	807-427-9	228114-02-1	2019	View substance registered dossier
LES DERIVES RESINIQUES ET TERPENIQUES	30 rue Gambetta B.P. 206 40105 Dax Cedex France	France	Cease Manufacture	(E,Z)-2,6-dimethylocta-2,4,6-triene	230-603-6	7216-56-0	2021	View substance registered dossier
Evonik Operations GmbH	Rellinghauser Straße 1-11 45128 Essen Germany	Germany	Cease Manufacture	(R)-1-chloro-2,3-epoxypropane	424-280-2	51594-55-9	2022	View substance registered dossier
Dynamit Nobel GmbH Explosivstoff- und Systemtechnik	Kalkstrasse 218 51377 Leverkusen Germany	Germany	Cease Manufacture	(R)-2-(2,4-Difluorphenyl)-1,1-difluor-3-(tetrazol-1-yl)-1-{5-[4-(2,2,2-trifluorethoxy)-phenyl]-2-pyridyl}-2-propanol-(R,R)-tartrate	845-262-4	1809816-36-1	2022	View substance registered dossier
COVANCE CLINICAL DEVELOPMENT SA 171	Parque Empresarial Las Tablas, Edificio 1 Calle Federico Mompou, 5 – 5 Planta 28050 Madrid Spain	Spain	Cease Manufacture	(R)-3-chloropropane-1,2-diol	435-560-9	57090-45-6	2012	View substance registered dossier
Bayer Agriculture bvba	Scheldelaan 460 B-2040 Antwerp Belgium	Belgium	Cease Manufacture	(RS)-3-dichloroacetyl-5-(2-furanyl)-2,2-dimethyloxazolidine	434-800-1	-	2020	View substance registered dossier
Janssen Pharmaceutica N.V.	Turnhoutseweg 30 2340 Beerse Belgium	Belgium	Cease Manufacture	(S)-(+)-2-(2-Chlorophenyl)-2-hydroxyacetic acid	700-307-6	52950-19-3	2019	View substance registered dossier
DSM Nutritional Products GmbH	Emil-Barell-Str. 3 79639 Grenzach-Wyhlen Germany	Germany	Cease Manufacture	(S)-1,1-diphenyl-1,2-propanediol	443-220-6	46755-94-6	2019	View substance registered dossier
Boehringer Ingelheim Pharma GmbH & Co. KG	Binger Strasse 173 55216 Ingelheim am Rhein Germany	Germany	Cease Manufacture	(S)-2,6-Diamino-4,5,6,7-tetrahydrobenzothiazole	600-715-3	106092-09-5	2020	View substance registered dossier
Cambrex Karlskoga AB	Bjorkborns Industriomrade 69185 Karlskoga Sweden	Sweden	Cease Manufacture	(S)-2-(1-aminopropyl)-5-fluoro-3-phenylquinazolin-4(3H)-one hydrochloride	942-180-1	-	2017	View substance registered dossier
Sicor - Società Italiana Corticosteroidi S.r.l.	Piazzale Luigi Cadorna 4 20123 Milano (MI) Italy	Italy	Cease Manufacture	(S)-2-amino-3-(3,4-dimethoxyphenyl)-2-methylpropiononitrile monohydrochloride	219-823-3	2544-13-0	2022	View substance registered dossier
Boehringer Ingelheim Pharma GmbH & Co. KG	Binger Strasse 173 55216 Ingelheim am Rhein Germany	Germany	Cease Manufacture	(S)-2-Amino-6-propionylamino-4,5,6,7-tetrahydrobenzothiazole	600-709-0	106006-84-2	2019	View substance registered dossier
Boehringer Ingelheim Pharma GmbH & Co. KG	Binger Strasse 173 55216 Ingelheim am Rhein Germany	Germany	Cease Manufacture	(S)-2-Amino-6-propylamino-4,5,6,7-tetrahydrobenzothiazole	600-593-1	104632-26-0	2019	View substance registered dossier
TÜV SÜD Industrie Service GmbH	Westendstr. 199 IS-CMS-MUC 80686 Munich Germany	Germany	Cease Manufacture	(S)-2-Hydroxy-3,3-dimethyl-4-butanolide	626-470-2	5405-40-3	2015	View substance registered dossier
Sicor - Società Italiana Corticosteroidi S.r.l.	Piazzale Luigi Cadorna 4 20123 Milano (MI) Italy	Italy	Cease Manufacture	(S)-3-(tert-butylamino)propane-1,2-diol	250-125-1	30315-46-9	2022	View substance registered dossier
Esteve Quimica, S.A.	Torre Esteve Passeig de la Zona Franca, 109, 4ª Planta 08038 Barcelona Barcelona Spain	Spain	Cease Manufacture	(S)-3-benzyloxycarbonyl-1,2,3,4-tetrahydro-isoquinolinium 4-methylbenzenesulfonate	406-960-0	77497-97-3	2017	View substance registered dossier
N.V. Ajinomoto OmniChem S.A.	Cooppallaan 91 9230 Wetteren Oost-Vlaanderen Belgium	Belgium	Cease Manufacture	(S)-3-Hydroxytetrahydrofurane	425-090-2	-	2020	View substance registered dossier
Boehringer Ingelheim Pharma GmbH & Co. KG	Binger Strasse 173 55216 Ingelheim am Rhein Germany	Germany	Cease Manufacture	(S)-3-Methyl-1-(2-piperidine-1-phenyl)butylamine compound with N-Acetyl-L-glutamic acid	606-883-4	219921-94-5	2023	View substance registered dossier
Boehringer Ingelheim Pharma GmbH & Co. KG	Binger Strasse 173 55216 Ingelheim am Rhein Germany	Germany	Cease Manufacture	(S)-3-Methyl-1-(2-piperidinophenyl)-1-butylamine	604-603-5	147769-93-5	2023	View substance registered dossier
Esteve Quimica, S.A.	Torre Esteve Passeig de la Zona Franca, 109, 4ª Planta 08038 Barcelona Barcelona Spain	Spain	Cease Manufacture	(S)-6-(2-(7-bromo-9,9-difluoro-9H-fluoren-2-yl)-2-oxoethyl) 5-tert-butyl 5-azaspiro[2.4]heptane-5,6-dicarboxylate	941-125-9	-	2021	View substance registered dossier
-	-	-	-	(S)-[2-(phenylmethoxy)propylidene]hydrazinecarboxylate, tert-butyle	439-220-0	-	-	View substance registered dossier
AstraZeneca	B313:5 AZ GlobalSHE- Chem.Reg. SE-15185 Södertälje Sweden	Sweden	Cease Manufacture	(S)-azetidine-2-carboxylic acid; 4-cyanobenzylamide hydrochloride	433-010-2	-	2012	View substance registered dossier
OLON Spa	Strada Rivoltana Km 6/7 20053 RODANO Milano Italy	Italy	Cease Manufacture	(S)-methyl 5-(4-(benzyloxy)phenyl)-3,4-dihydro-2H-pyrrole-2-carboxylate	815-198-1	934240-38-7	2022	View substance registered dossier
Esteve Quimica, S.A.	Torre Esteve Passeig de la Zona Franca, 109, 4ª Planta 08038 Barcelona Barcelona Spain	Spain	Cease Manufacture	(S)-tert-butyl 6-(5-(7-bromo-9,9-difluoro-9H-fluoren-2-yl)-1H-imidazol-2-yl)-5-azaspiro[2.4]heptane-5-carboxylate	939-899-8	1441670-89-8	2021	View substance registered dossier
Cambrex Karlskoga AB	Bjorkborns Industriomrade 69185 Karlskoga Sweden	Sweden	Cease Manufacture	(S)-tert-butyl(1-((3-fluoro-2-(phenylcarbamoyl)phenyl)amino)-1-oxobutan-2 yl)carbamate	942-159-7	-	2017	View substance registered dossier
Bayer AG	Kaiser-Wilhelm-Allee 1 51373 Leverkusen Germany	Germany	Cease Manufacture	(tert-Butoxycarbonyl)methyl 2-[1-[(4-chlorophenyl)carbonyl]-5-methoxy-2-methylindol-3-yl]acetate	616-210-6	75302-98-6	2021	View substance registered dossier
Dow Silicones Belgium SPRL OR-1	rue Jules Bordet Parc industriel C 7180 Seneffe Belgium	Belgium	Cease Manufacture	(trimethoxysilyl)methyl prop-2-enoate	700-313-9	21134-38-3	2012	View substance registered dossier
Nouryon Functional Chemicals B.V.	Haaksbergweg 88 1101 BZ Amsterdam The Netherlands Netherlands	Netherlands	Cease Manufacture	(TRIMETHYLENEDINITRILO)TETRAKISACETONITRILE	429-330-7	-	2014	View substance registered dossier
Esteve Quimica, S.A.	Torre Esteve Passeig de la Zona Franca, 109, 4ª Planta 08038 Barcelona Barcelona Spain	Spain	Cease Manufacture	(Z)-4-hydroxy-4-(6-methoxynaphthalen-2-yl)but-3-en-2-one	700-075-6	218768-11-7	2017	View substance registered dossier
Sandoz GmbH	Biochemiestr. 10 6250 Kundl Austria	Austria	Cease Manufacture	(Z)-5-Amino-α-(methoxyimino)-1,2,4-thiadiazole-3-acetic acid	456-150-6	-	2021	View substance registered dossier
Nouryon Surface Chemistry AB	Stenunge Allé 3 S-44485 Stenungsund Sweden	Sweden	Cease Manufacture	(Z)-Octadec-9-enylamine, ethoxylated	500-048-7	26635-93-8	2021	View substance registered dossier
NetSun EU B.V.	Blaak 40, Fifth Floor 3011 TA Rotterdam Netherlands	Netherlands	Cease Manufacture	(±)-2-(6-methoxy-2-naphthyl)propionic acid	247-485-7	26159-31-9	2019	View substance registered dossier
Stadex Nederland BV	Boxbergerweg 119 7431PM Diepenveen Netherlands	Netherlands	Cease Manufacture	(±)-2-(6-methoxy-2-naphthyl)propionic acid	247-485-7	26159-31-9	2013	View substance registered dossier
Evotec DS Germany GmbH	Kantstrasse 2 33790 Halle/ Westf. Germany	Germany	Cease Manufacture	(±)-2-aminododecanoic acid	252-454-6	35237-37-7	2023	View substance registered dossier
F.I.S. Fabbrica Italiana Sintetici S.p.a.	Viale Milano, 26 36075 Montecchio Maggiore (VI) Veneto Italy	Italy	Cease Manufacture	(±)-3-hexyl-5,6-dihydro-4-hydroxy-6-undecyl-2H-Pyran-2-one	603-982-4	136890-21-6	2015	View substance registered dossier
Patheon Austria GmbH & Co KG	St. Peter Strasse 25 4020 Linz Austria	Austria	Cease Manufacture	(±)-3-hexyl-5,6-dihydro-4-hydroxy-6-undecyl-2H-Pyran-2-one	603-982-4	136890-21-6	2020	View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant Belgian competent national authority.	-	-	No longer Valid	(η-cumene)-(η-cyclopentadienyl)iron(II) trifluoromethane-sulfonate	407-880-9	117549-13-0	2022	View substance registered dossier
Colors & Effects France S.A.S.	Rue de la Chapelle 28 68330 Huningue France	France	Cease Manufacture	(η-cumene)-(η-cyclopentadienyl)iron(II) trifluoromethane-sulfonate	407-880-9	117549-13-0	2018	View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant Dutch competent national authority.	-	-	No longer Valid	(η-cumene)-(η-cyclopentadienyl)iron(II) trifluoromethane-sulfonate	407-880-9	117549-13-0	2022	View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant Italian competent national authority.	-	-	No longer Valid	(η-cumene)-(η-cyclopentadienyl)iron(II) trifluoromethane-sulfonate	407-880-9	117549-13-0	2022	View substance registered dossier
Huntsman Advanced Materials (Europe) BV	Everslaan 45 B-3078 Everberg Belgium	Belgium	Cease Manufacture	(η-cumene)-(η-cyclopentadienyl)iron(II) trifluoromethane-sulfonate	407-880-9	117549-13-0	2022	View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant German competent national authority.	-	-	No longer Valid	(η-cumene)-(η-cyclopentadienyl)iron(II) trifluoromethane-sulfonate	407-880-9	117549-13-0	2022	View substance registered dossier
Evonik Operations GmbH	Rellinghauser Straße 1-11 45128 Essen Germany	Germany	Cease Manufacture	1,1'-(1,3-phenylenedioxy)bis(3-(2-(prop-2-enyl)phenoxy)propan-2-ol)	405-840-5	110866-35-8	2018	View substance registered dossier
Global Product Compliance (Europe) AB	IDEON, Beta 5, Scheelevägen 17 22363 Lund Sweden	Sweden	Cease Manufacture	1,1'-(4-chlorobutylidene)bis[4-fluorobenzene]	221-998-6	3312-04-7	2022	View substance registered dossier
BASF SE	Carl-Bosch-Str. 38 67056 Ludwigshafen am Rhein Rheinland-Pfalz Germany	Germany	Cease Manufacture	1,1'-(tridecylimino)bis-2-propanol	613-099-6	62889-66-1	2019	View substance registered dossier
BASF SE	Carl-Bosch-Str. 38 67056 Ludwigshafen am Rhein Rheinland-Pfalz Germany	Germany	Cease Manufacture	1,1'-[methylenebis(oxy)]dibutane	219-909-0	2568-90-3	2020	View substance registered dossier
Stewardship Chemicals 40	Długosza 67 43-188 Orzesze Poland	Poland	Cease Manufacture	1,1'-methylenebis[4-fluorobenzene]	207-274-2	457-68-1	2023	View substance registered dossier
-	-	-	-	1,1,1,2,2,3,3,4,4,5,5,6,6-tridecafluorotetradecane	432-570-5	-	-	View substance registered dossier
Merck Performance Materials GmbH	Rheingaustrasse 190-196 65203 Wiesbaden Germany	Germany	Cease Manufacture	1,1,1-Tris(p-hydroxyphenyl)ethane, mixed esters with 3-Diazo-3,4-dihydro-4-oxonaphthalene 2-sulphonic acid and 6-Diazo-5,6-dihydro-5-oxonaphthalene 2-sulphonic acid	422-760-6	-	2019	View substance registered dossier
3M Belgium BVBA/SPRL (OR1)	Hermeslaan 7 1831 Diegem Belgium	Belgium	Cease Manufacture	1,1,2,2,3,3,4,4,4-nonafluoro-N,N-bis(2-hydroxyethyl)butane-1-sulphonamide	252-044-7	34455-00-0	2022	View substance registered dossier
3M Belgium BVBA/SPRL	Hermeslaan 7 1831 Diegem Belgium	Belgium	Cease Manufacture	1,1,2,2,3,3,4,4,4-nonafluoro-N-methylbutane-1-sulfonamide	614-396-3	68298-12-4	2022	View substance registered dossier
WeylChem Lamotte S.A.S	Rue du Flottage B.P. 1 60350 Trosly Breuil France	France	Cease Manufacture	1,1,2,2-tetramethoxyethane	463-280-7	-	2019	View substance registered dossier
Global Product Compliance (Europe) AB	IDEON, Beta 5, Scheelevägen 17 22363 Lund Sweden	Sweden	Cease Manufacture	1,1-diethoxy-3,7-dimethylocta-2,6-diene	231-323-7	7492-66-2	2022	View substance registered dossier
Boehringer Ingelheim Pharma GmbH & Co. KG	Binger Strasse 173 55216 Ingelheim am Rhein Germany	Germany	Cease Manufacture	1,1-dimethylethyl 4'-(bromomethyl)biphenyl-2-carboxylate	442-850-9	114772-40-6	2015	View substance registered dossier
Cytec Industries BV as OR for Solvay Solutions UK Limited	Weena 505 3013 AL Rotterdam Rotterdam Netherlands Netherlands	Netherlands	Cease Manufacture	1,12-bis (diisopropyl phosphoryl) dodecane	919-645-2	-	2021	View substance registered dossier
BASF SE	Carl-Bosch-Str. 38 67056 Ludwigshafen am Rhein Rheinland-Pfalz Germany	Germany	Cease Manufacture	1,2,3,4-tetrahydroisoquinoline	202-050-0	91-21-4	2022	View substance registered dossier
-	-	-	-	1,2,3-triaqua-1,2:1,2:1,3:1,3:2,3:2,3-hexa-μ-acetato-(O,O')-μ3-oxo-triangulo-triiridium acetate	417-670-9	-	-	View substance registered dossier
Janssen Pharmaceutica N.V.	Turnhoutseweg 30 2340 Beerse Belgium	Belgium	Cease Manufacture	1,2,4-Thiadiazole-3-ethanethioic acid, 5-amino-alpha-[(triphenylmethoxy)imino]-, S-2-benzothiazolyl ester, (alphaZ)-	447-420-4	-	2019	View substance registered dossier
Ineos Solvents Germany GmbH	Roemerstr. 733 47443 Moers Germany	Germany	Cease Manufacture	1,2-Benzenedicarboxylic acid, di-C6-10-alkyl esters	271-094-0	68515-51-5	2018	View substance registered dossier
AllessaProduktion GmbH	Alt-Fechenheim 34 60386 Frankfurt am Main Germany	Germany	Cease Manufacture	1,2-Bis(2-aminophenoxy)ethane	459-990-1	52411-34-4	2019	View substance registered dossier
FujiFilm Manufacturing Europe BV	Oudenstaart 1 5047 TK Tilburg Netherlands	Netherlands	Cease Manufacture	1,2-bis(vinylsulfonylacetamido)ethane	404-790-1	66710-66-5	2019	View substance registered dossier
Huntsman Textile Effects (Germany) GmbH	Rehlinger Str. 1 D-86462 Langweid a.Lech Germany	Germany	Cease Manufacture	1,2-bis[4-fluoro-6-{4-sulfo-5-(2-(4-sulfonaphtalene-3-ylazo)-1-hydroxy-3,6-disulfo-8-aminonaphthalene-7-ylazo)phenylamino}-1,3,5-triazin-2-ylamino]ethane;x-sodium, y-potassium salts x = 7,755 y = 0,245	417-610-1	155522-09-1	2014	View substance registered dossier
Vlisco Netherlands BV	Binnen Parallelweg 27 5701 PH Helmond NB Netherlands	Netherlands	Cease Manufacture	1,2-dihydroxyanthraquinone	200-782-5	72-48-0	2021	View substance registered dossier
-	-	-	-	1,2-Ethanediamine, N-(5-methoxy-2-nitrophenyl)-, monohydrochloride	415-480-0	86419-69-4	-	View substance registered dossier
BASF SE	Carl-Bosch-Str. 38 67056 Ludwigshafen am Rhein Rheinland-Pfalz Germany	Germany	Cease Manufacture	1,3,5-Benzenetricarboxylic acid, copper(2+) salt (2:3)	813-272-8	309721-49-1	2016	View substance registered dossier
REACH COMPLIANCE SERVICES LIMITED	Suite 1E, Paramount Court, Corrig Road, Sandyford Dublin 18 Dublin Ireland	Ireland	Cease Manufacture	1,3,5-triazine-2,4,6-triyltrinitrilohexamethanol	208-503-9	531-18-0	2016	View substance registered dossier
BASF Lampertheim GmbH	Chemiestrasse 22 68619 Lampertheim Germany	Germany	Cease Manufacture	1,3,5-tris(3,5-dicyclohexyl-4-hydroxybenzyl)perhydro-1,3,5-triazine-2,4,6-trione	404-180-5	-	2018	View substance registered dossier
Global Product Compliance (Europe) AB	IDEON, Beta 5, Scheelevägen 17 22363 Lund Sweden	Sweden	Cease Manufacture	1,3-Benzenedisulfonic acid, 4,4'-[1,2-ethenediylbis[(3-sulfo-4,1-phenylene)imino(6-chloro-1,3,5-triazine-4,2-diyl)imino]]bis[6-[[5-(aminocarbonyl)-1-ethyl-1,6-dihydro-2-hydroxy-4-methyl-6-oxo-3-pyridinyl]azo]-, hexasodium salt	273-662-3	68991-98-0	2022	View substance registered dossier
LAXMI ORGANIC INDUSTRIES (EUROPE) B.V.	BURGEMEESTER FEITHPLEIN 11 2273 BZ VOORBURG Netherlands	Netherlands	Cease Manufacture	1,3-benzodioxolane	205-992-0	274-09-9	2019	View substance registered dossier
FujiFilm Manufacturing Europe BV	Oudenstaart 1 5047 TK Tilburg Netherlands	Netherlands	Cease Manufacture	1,3-bis(vinylsulfonylacetamido)propane	428-350-3	93629-90-4	2019	View substance registered dossier
Bruno Bock GmbH	Eichholzer Straße 23 21436 Marschacht Lower Saxony Germany	Germany	Cease Manufacture	1,3-bis[(2-hydroxyethyl)sulfanyl]propan-2-ol	700-829-4	5324-06-1	2020	View substance registered dossier
Janssen Pharmaceutica N.V.	Turnhoutseweg 30 2340 Beerse Belgium	Belgium	Cease Manufacture	1,3-dichloro-2-methoxy-5-nitrobenzene	403-350-6	17742-69-7	2019	View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant Spanish competent national authority.	-	-	No longer Valid	1,3-dichloro-4-fluorobenzene	406-160-1	1435-48-9	2022	View substance registered dossier
Clariant Produkte (Deutschland) GmbH	August-Laubenheimer-Straße 1 Global Product Stewardship 65929 Frankfurt am Main Germany	Germany	Cease Manufacture	1,3-dichloro-4-fluorobenzene	406-160-1	1435-48-9	2022	View substance registered dossier
Global Product Compliance (Europe) AB	IDEON, Beta 5, Scheelevägen 17 223 63 Lund Sweden	Sweden	Cease Manufacture	1,3-dihydro-1-oxoisobenzofuran-5-carbonitrile	279-900-2	82104-74-3	2022	View substance registered dossier
Global Product Compliance (Europe) AB	IDEON, Beta 5, Scheelevägen 17 22363 Lund Sweden	Sweden	Cease Manufacture	1,3-dihydro-5-methoxy-2H-benzimidazole-2-thione	253-326-2	37052-78-1	2022	View substance registered dossier
LABSO Chimie Fine	20, rue Jean Duvert 33920 Blanquefort France	France	Cease Manufacture	1,3-Dioxan-2-one	423-980-5	-	2016	View substance registered dossier
BASF SE	Carl-Bosch-Str. 38 67056 Ludwigshafen am Rhein Rheinland-Pfalz Germany	Germany	Cease Manufacture	1,3-dioxepane	208-015-6	505-65-7	2020	View substance registered dossier
Esteve Quimica, S.A.	Torre Esteve Passeig de la Zona Franca, 109, 4ª Planta 08038 Barcelona Barcelona Spain	Spain	Cease Manufacture	1,3-Dioxolane-4-methanol, 2-(2,4-dichlorophenyl)-2-(1H-imidazol-1-ylmethyl)-, 4-methylbenzenesulfonate (ester), (2R,4R)-rel-	603-791-6	134071-44-6	2017	View substance registered dossier
ARCHROMA IBÉRICA, S.L.	ZAL-Prat c/Cal Coracero, 46-56 08820 El Prat de Llobregat Spain	Spain	Cease Manufacture	1,3-disodium, 7-(2-{4-[(4-{2-[2-(cyanoamino)-4,6-dihydroxypyrimidin-5-yl]diazen-1-yl}benzene)amido]-3-methoxyphenyl}diazen-1-yl)naphthalene-1,3-disulfonate	931-147-7	-	2023	View substance registered dossier
-	-	-	-	1,4-Benzene disulfonic acid, 2,2'-[1,2-ethenediylbis[(3-sulfo-4 ,1-phenylene)imino[6-(1-methylpropyl)amino]-1,3,5-triazine-4 ,2-diyl]imino]]bis-, hexasodium salt	451-550-7	714252-10-5	-	View substance registered dossier
[Confidential]	-	-	-	1,4-Benzenedicarboxylic acid, compd. with 1,6-hexanediamine (1:1)	700-230-8	3160-86-9	-	View substance registered dossier
Oxxynova GmbH	Borsteler Weg 31595 Steyerberg Lower Saxony Germany	Germany	Cease Manufacture	1,4-Benzenedicarboxylic acid, dimethyl ester, manuf. of, by-products from	273-521-6	68988-22-7	2023	View substance registered dossier
Stepan Netherlands B.V.	Maltaweg 3-2 4389 PV RITTHEM Netherlands	Netherlands	Cease Manufacture	1,4-Benzenedicarboxylic acid, dimethyl ester, manuf. of, by-products from	273-521-6	68988-22-7	2023	View substance registered dossier
Indorama Ventures Polymers Germany GmbH	Philipp Reis Strasse 4 65795 Hattersheim Germany	Germany	Cease Manufacture	1,4-Benzenedicarboxylic acid, dimethyl ester, manuf. of, by-products from	273-521-6	68988-22-7	2015	View substance registered dossier
NOVEAL	16 rue Maurice Berteaux 95500 LE THILLAY France	France	Cease Manufacture	1,4-bis(2,3-dihydroxypropylamino)anthraquinone	421-470-7	99788-75-7	2022	View substance registered dossier
Global Product Compliance (Europe) AB	IDEON, Beta 5, Scheelevägen 17 22363 Lund Sweden	Sweden	Cease Manufacture	1,4-bis[(2-methylphenyl)amino]anthraquinone	229-792-8	6737-68-4	2022	View substance registered dossier
Global Product Compliance (Europe) AB	IDEON, Beta 5, Scheelevägen 17 22363 Lund Sweden	Sweden	Cease Manufacture	1,4-diamino-2,3-dichloroanthraquinone	201-348-8	81-42-5	2022