Registered substances

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New Data Availability System

A new Data Availability System is being developed by ECHA. To begin with this system will take over the responsibility of making REACH registration data available, once it is ready. We expect the first version to be publicly available by the end of 2023.

Since ECHA aims to devote our maximum effort to this new system, we can no longer maintain REACH registration data on the current Dissemination Platform. As such once the IUCLID format change begins on 19th May 2023 we will no longer update REACH registered substance factsheets. The factsheets will remain online, but will not be updated.

New and updated REACH registration submissions, as well as all registrations on file, will be made available in the new system when it is ready. We will inform you of what you can expect in the new system, along with details of when and where to find it.

We appreciate your understanding in the meantime.

DISSEMINATION
PLATFORM

REACH - Registration, Evaluation, Authorisation and Restriction of Chemicals Regulation

Registered Substances Factsheets

Substances which have been registered and can be placed on the EEA market by those companies with a valid registration

Showing 901 - 1,000 of 26,866 results.

Name	EC / List no.	CAS no.	Registration Status	Registration type	Submission type	Total tonnage band	Last Updated	Details
(6ALPHA,11BETA,16ALPHA,17ALPHA)-6,9-DIFLUORO-11-HYDRO XY-16-METHYL-3-OXO-17- (1-OXOPROPOXY)ANDROSTA-1,4-DIENE-CARBOTHIOIC ACID	617-084-5	80474-45-9	Active	Intermediate	Joint	Intermediate use only	29-07-2022	View substance registered dossier
(6R)-6-(dimethylamino)-4,4-diphenylheptan-3-one	603-081-6	125-58-6	Active	Intermediate	Joint	Intermediate use only	14-02-2022	View substance registered dossier
(6R)-6-Dimethylamino-4,4-diphenyl-heptan-3-one; compound with 2-(toluene-4-sulfonylamino)-pentanedioic acid	921-925-4	-	Active	Intermediate	Joint	Intermediate use only	14-02-2022	View substance registered dossier
(6R,7R)-7-hydroxy-6-[(propan-2-yl)amino]-4,5,6,7-tetrahydroimidazo[4,5,1-jk][1]benzazepin-2(1H)-one	862-404-0	119520-05-7	Active	Intermediate	Joint	Intermediate use only	24-08-2022	View substance registered dossier
(6R,7R)-3-[(5-amino-4-{[(2-aminoethyl)carbamoyl]amino}-1-methyl-1H-pyrazol-2-ium-2-yl)methyl]-7-{[(2Z)-2-(5-amino-1,2,4-thiadiazol-3-yl)-2-{[(2-carboxypropan-2-yl)oxy]imino}acetyl]amino}-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate trifluoroacetate (1:3)	939-998-6	-	Cease Manufacture	Intermediate	Joint	Cease manufacture	24-11-2014	View substance registered dossier
(6R,7R)-3-[(5-amino-4-{[(2-aminoethyl)carbamoyl]amino}-1-methyl-1H-pyrazol-2-ium-2-yl)methyl]-7-{[(2Z)-2-(5-amino-1,2,4-thiadiazol-3-yl)-2-{[(2-carboxypropan-2-yl)oxy]imino}acetyl]amino}-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate trifluoroacetate (1:3)	939-998-6	-	Active	Intermediate	Individual	Intermediate use only	18-12-2013	View substance registered dossier
(6R,7R)-3-[[(Aminocarbonyl)oxy]methyl]-7-[[(2Z)-2-furanyl(methoxyimino)acetyl]amino]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-en-2-carboxylic acid, 1-butylammonium salt	439-350-8	-	Cease Manufacture	NONS	Individual	Cease manufacture	22-12-2010	View substance registered dossier
(6R,7R)-3-chloromethyl-7-{(Z)-2-(5-amino-1,2,4-thiadiazol-3-yl)2-[(1-carboxy-1-methylethoxy)imino]acetylamino}-8-oxo-5-thia-1-azbicyclo[4.2.0]oct-2-ene-2-carboxylic acid p-methoxybenzyl ester	939-996-5	689294-28-8	Active	Intermediate	Joint	Intermediate use only	08-04-2014	View substance registered dossier
(6R,7R)-3-chloromethyl-7-{(Z)-2-(5-amino-1,2,4-thiadiazol-3-yl)2-[(1-carboxy-1-methylethoxy)imino]acetylamino}-8-oxo-5-thia-1-azbicyclo[4.2.0]oct-2-ene-2-carboxylic acid p-methoxybenzyl ester	939-996-5	689294-28-8	Active	Intermediate	Individual	Intermediate use only	26-02-2014	View substance registered dossier
(6R,7R)-7-[((2Z)-2-[({2-[(1,1-dimethylethyl)oxy]-1,1-dimethyl-2-oxoethyl}oxy)imino]-2-{2-[(triphenylmethyl)amino]-1,3-thiazol-4-yl}acetyl)amino]-8-oxo-3-(1-pyridiniumylmethyl)-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate	617-560-2	84377-83-3	No longer Valid	Full	Joint	No longer valid	15-11-2018	View substance registered dossier
(6R,7R)-7-[[(2Z)-(2-Aminothiazol-4-yl)(methoxy-imino)acetyl]amino]-3-[1-methylpyrrolidinio)methyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate dihydrochloride	827-945-9	107648-80-6	Active	Intermediate	Joint	Intermediate use only	21-09-2018	View substance registered dossier
(6R,7R)-7-[[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-[2-methyl-1-[(2-methylpropan-2-yl)oxy]-1-oxopropan-2-yl]oxyiminoacetyl]amino]-8-oxo-3-(pyridin-1-ium-1-ylmethyl)-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate	600-349-4	102772-66-7	Active	Intermediate	Joint	Intermediate use only	08-05-2018	View substance registered dossier
(6R,7R)-7-[[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-methoxyiminoacetyl]amino]-3-(furan-2-carbonylsulfanylmethyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid;hydrochloride	600-507-2	103980-44-5	Cease Manufacture	Intermediate	Joint	Cease manufacture	03-04-2018	View substance registered dossier
(6R,7R)-7-[[(2Z)-2-(5-amino-1,2,4-thiadiazol-3-yl)-2-[(triphenylmethoxy)imino]acethyl]amino]-3-(hydroxymethyl)-8-oxo-5thia-1-azabicyclo[4.2.0]oct-2-ene-carboxylic acid diphenylmethyl ester	609-461-8	376653-36-0	Active	Full	Joint	≥ 1 to < 10 tonnes	30-07-2018	View substance registered dossier
(6R,7R)-7-[[(2Z)-2-(5-amino-1,2,4-thiadiazol-3-yl)-2-[(triphenylmethoxy)imino]acetyl]amino]-3-[(E)-[(3'R)-1'-[(1,1-dimethylethoxy)carbonyl]-2-oxo-[1,3'-bipyrrolidin]-3-ylidene]methyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid diphenylmethyl ester	609-463-9	376653-41-7	Active	Full	Joint	≥ 1 to < 10 tonnes	30-07-2018	View substance registered dossier
(6R,7R)-7-amino-3-(5H-imidazo[1,2-b]pyridazin-1-ylmethyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid;hydroiodide	606-382-0	197897-11-3	Cease Manufacture	Intermediate	Individual	Cease manufacture	20-04-2018	View substance registered dossier
(6R,7R)-7-amino-3-{[(furan-2-ylcarbonyl)sulfanyl]methyl}-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid	617-065-1	80370-59-8	Cease Manufacture	Intermediate	Joint	Cease manufacture	03-04-2018	View substance registered dossier
(6R,7R)-7-Amino-8-oxo-3-vinyl-5-thia-1-aza-bicyclo[4,2,0]oct-2-ene-2-carboxylic acid	438-350-5	79349-82-9	Active	NONS	Individual	Tonnage data confidential	20-12-2010	View substance registered dossier
(6R,7R)-7-Amino-8-oxo-3-vinyl-5-thia-1-aza-bicyclo[4,2,0]oct-2-ene-2-carboxylic acid	438-350-5	79349-82-9	Active	Intermediate	Joint	Intermediate use only	21-12-2017	View substance registered dossier
(6R,7R)-7-{[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetyl]amino}-3-({[5-(carboxymethyl)-4-methyl-1,3-thiazol-2-yl]sulfanyl}methyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid	700-301-3	69739-16-8	Cease Manufacture	Intermediate	Individual	Cease manufacture	04-06-2009	View substance registered dossier
(6R,7R)-benzhydryl 3-hydroxy-8-oxo-7-(2-phenylacetamido)-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate	611-177-4	54639-48-4	Active	Intermediate	Joint	Intermediate use only	03-06-2013	View substance registered dossier
(6R,7R,14S)-17-cyano-7,8-dihydro-7-[(1S)-1-hydroxy-1,2,2-trimethylpropyl]-3,6-O-dimethyl-6,14-ethano-17-normorphine	921-415-1	-	Active	Intermediate	Individual	Intermediate use only	01-09-2016	View substance registered dossier
(6R,7R,14S)-7,8-dihydro-7-[(1S)-1-hydroxy-1,2,2-trimethylpropyl]-3,6-O-dimethyl-6,14-ethanomorphine	918-453-6	-	Active	Intermediate	Individual	Intermediate use only	31-08-2016	View substance registered dossier
(6R,7R,14S)-7,8-dihydro-7-[(1S)-1-hydroxy-1,2,2-trimethylpropyl]-6-O-methyl-6,14-ethano-17-normorphine	917-585-1	-	Active	Intermediate	Individual	Intermediate use only	01-09-2016	View substance registered dossier
(6R,7S)-Benzhydryl 7-amino-7-methoxy-3-((1-methyl-1H-tetrazol-5-ylthio)methyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate	611-404-7	56610-72-1	Active	Intermediate	Joint	Intermediate use only	02-11-2016	View substance registered dossier
(6R-trans)-1-((7-Ammonio-2-carboxylato-8-oxo-5-thia-1-azabicyclo-(4.2.0)oct-2-en-3-yl)methyl)pyridinium iodide	423-260-0	100988-63-4	Cease Manufacture	NONS	Individual	Cease manufacture	29-10-2012	View substance registered dossier
(6R-trans)-7-amino-3-(hydroxymethyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid	239-787-2	15690-38-7	Active	Intermediate	Joint	Intermediate use only	19-12-2018	View substance registered dossier
(6R-trans)-7-amino-3-[([5-(carboxymethyl)-4-methyl-2-thiazolyl]thio)methyl]-8-oxo- 5-thia-1-azabicyclo-[4.2.0]oct-2-en-2-carboxylic acid TACS	403-690-5	111298-82-9	Active	NONS	Individual	Tonnage data confidential	10-11-2008	View substance registered dossier
(6R-trans)-7-amino-3-[[(5-methyl-1,3,4-thiadiazol-2-yl)thio]methyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid	250-099-1	30246-33-4	Active	Intermediate	Joint	Intermediate use only	16-10-2019	View substance registered dossier
(6R-trans)-7-amino-3-[[[5-(carboxymethyl)-4-methyl-2-thiazolyl]thio]methyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid	619-847-8	111298-82-9	Cease Manufacture	Intermediate	Individual	Cease manufacture	26-03-2009	View substance registered dossier
(6R-trans)-7-amino-3-chloro-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid	258-907-4	53994-69-7	Active	Intermediate	Joint	Intermediate use only	16-10-2019	View substance registered dossier
(6R-trans)-7-amino-3-methyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid	244-870-1	22252-43-3	Active	Intermediate	Joint	Intermediate use only	16-12-2019	View substance registered dossier
(6R-trans)-7-amino-8-oxo-3-[[(1,2,5,6-tetrahydro-2-methyl-5,6-dioxo-1,2,4-triazin-3-yl)thio]methyl]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid	261-491-7	58909-56-1	Active	Intermediate	Joint	Intermediate use only	10-07-2019	View substance registered dossier
(6R-trans)-7-amino-8-oxo-3-[[(1,2,5,6-tetrahydro-2-methyl-5,6-dioxo-1,2,4-triazin-3-yl)thio]methyl]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid	261-491-7	58909-56-1	Cease Manufacture	Full	Joint	Cease manufacture	03-05-2018	View substance registered dossier
(6RS,7RS)3,5,5,6,7,8,8-heptamethyl-5,6,7,8-tetrahydronaphthalene-2-carbaldehyde	482-190-9	127459-79-4	Active	NONS	Joint	Tonnage data confidential	10-11-2008	View substance registered dossier
(6S)-1'-tert-butyl-3-chlorospiro[5,7-dihydrocyclopenta[b]pyridine-6,3'-pyrrolo[2,3-b]pyridine]-2'-one	881-148-0	1455358-14-1	Active	Intermediate	Joint	Intermediate use only	14-03-2022	View substance registered dossier
(6S)-2,6-dimethyloct-2-ene-8,8-diyl diacetate	949-377-1	-	Active	Intermediate	Joint	Intermediate use only	10-05-2019	View substance registered dossier
(6S)-6-(propylamino)-5,6,7,8-tetrahydronaphthalen-1-ol hydrobromide (1:1)	605-420-3	165950-84-5	Active	Full	Joint	≥ 1 to < 10 tonnes	26-11-2020	View substance registered dossier
(6S)-6-methyl-5,6-Dihydro-4H-thieno[2,3-b]thiopyran4-one-7,7-dioxide	431-140-4	-	Active	Intermediate	Joint	Intermediate use only	13-11-2017	View substance registered dossier
(6S)-6-methyl-5,6-Dihydro-4H-thieno[2,3-b]thiopyran4-one-7,7-dioxide	431-140-4	-	Active	NONS	Individual	Tonnage data confidential	10-11-2008	View substance registered dossier
(6S)-6-{propyl[2-(2-thienyl)ethyl]amino}-5,6,7,8-tetrahydronaphthalen-1-ol hydrochloride (1:1)	603-080-0	125572-93-2	Active	Full	Joint	≥ 1 to < 10 tonnes	17-12-2020	View substance registered dossier
(6S,12aR)-3,10-Dibromo-12,12a-dihydro-6-phenyl-6H-indolo[1,2-c][1,3]benzoxazine	813-155-1	1585969-16-9	Active	Intermediate	Individual	Intermediate use only	21-09-2016	View substance registered dossier
(6S,7S)-7-Amino-3-(methoxymethyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid	435-680-1	-	Cease Manufacture	Full	Individual	Cease manufacture	17-05-2018	View substance registered dossier
(6S,8S,9S,10R,11S,13S,14S,17R)-17-acetyl-11,17-dihydroxy-6,10,13-trimethyl-2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthren-3-one	615-123-0	7055-53-0	Active	Intermediate	Joint	Intermediate use only	28-01-2022	View substance registered dossier
(6S,9R,10S,11S,13S,14S,16R,17R)-17-(((diethylamino)(ethyl)-λ4-sulfaneyl)carbonyl)-6,9-difluoro-11-hydroxy-10,13,16-trimethyl-3-oxo-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[α]phenanthren-17-yl propionate	884-371-1	577970-31-1	Active	Intermediate	Joint	Intermediate use only	29-07-2022	View substance registered dossier
(6S,9R,10S,11S,13S,14S,16R,17R)-6,9-difluoro-11-hydroxy-10,13,16-trimethyl-3-oxo-17-(propionyloxy)-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthrene-17-carboxylic acid	813-979-1	65429-42-7	Active	Intermediate	Joint	Intermediate use only	29-07-2022	View substance registered dossier
(6S,9R,10S,11S,13S,16R,17R)-6,9-difluoro-11,17-dihydroxy-10,13,16-trimethyl-3-oxo-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthrene-17-carboxylic acid	434-320-0	-	Cease Manufacture	NONS	Joint	Cease manufacture	15-11-2012	View substance registered dossier
(6S,9R,10S,11S,13S,16R,17R)-6,9-difluoro-11,17-dihydroxy-10,13,16-trimethyl-3-oxo-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthrene-17-carboxylic acid	434-320-0	-	Active	Intermediate	Joint	Intermediate use only	08-10-2021	View substance registered dossier
(6Z)-6-(hydroxyimino)-5,6-dihydroimidazo[4,5,1-jk][1]benzazepine-2,7(1H,4H)-dione	695-945-4	-	Active	Intermediate	Joint	Intermediate use only	23-06-2022	View substance registered dossier
(6β)-6,19-epoxyandrost-4-ene-3,17-dione	433-490-3	6563-83-3	Active	NONS	Individual	Tonnage data confidential	15-12-2008	View substance registered dossier
(7-Bromobenzofuran-5-yl)methanol	876-095-5	286836-24-6	Active	Intermediate	Joint	Intermediate use only	24-02-2022	View substance registered dossier
(7-Hydroxy-2-naphthyl)-trimethylammonium methyl sulphate	807-380-4	377734-55-9	No longer Valid	Full	Joint	No longer valid	26-03-2018	View substance registered dossier
(7-Methoxy-3,4-dihydronaphthalen-1-yl)acetonitrile	617-813-7	861960-34-1	Active	Full	Joint	≥ 1 to < 10 tonnes	11-05-2018	View substance registered dossier
(7-methoxynaphthalen-1-yl)acetonitrile	461-670-1	-	Active	Full	Individual	≥ 1 to < 10 tonnes	08-06-2010	View substance registered dossier
(7-methoxynaphthalen-1-yl)acetonitrile	461-670-1	-	Active	Intermediate	Joint	Intermediate use only	14-12-2021	View substance registered dossier
(7-methoxynaphthalen-1-yl)acetonitrile	461-670-1	-	Active	NONS	Individual	Tonnage data confidential	10-11-2008	View substance registered dossier
(7-Phenylsulfonyl-6-nitro-chinazolin-4-yl)-(3-chlor-4-fluor-phenyl)-amin	620-069-6	945553-94-6	Active	Intermediate	Joint	Intermediate use only	26-04-2018	View substance registered dossier
(7R)-4-(5-Chloro-1,3-benzoxazol-2-yl)-7-methyl-1,4-diazepan-1-ium chloride	690-742-7	1266664-66-7	Active	Full	Joint	≥ 10 to < 100 tonnes	20-05-2020	View substance registered dossier
(7R)-7-(4-carboxybutanamido)cephalosporanate amidohydrolase (enzyme substance)	611-406-8	56645-46-6	Cease Manufacture	Full	Joint	Cease manufacture	01-10-2018	View substance registered dossier
(7R,13S,17S)-13-methyl-3-oxo-7-(9-((4,4,5,5,5-pentafluoropentyl)thio)nonyl)-2,3,6,7,8,9,10,11,12,13,14,15,16, 17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl acetate	642-947-8	415927-29-6	Active	Intermediate	Individual	Intermediate use only	04-04-2018	View substance registered dossier
(7R,13S,17S)-13-methyl-3-oxo-7-(9-((4,4,5,5,5-pentafluoropentyl)thio)nonyl)-2,3,6,7,8,9,10,11,12,13,14,15,16, 17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl acetate and (7S,13S,17S)-13-methyl-3-oxo-7-(9-((4,4,5,5,5-pentafluoropentyl)thio)nonyl)-2,3,6, 7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl acetate	943-624-7	-	Active	Intermediate	Joint	Intermediate use only	01-03-2022	View substance registered dossier
(7R,8R,9S,13S,14S,17S)-13-methyl-7-(9-((4,4,5,5,5-pentafluoropentyl)thio)nonyl)-7,8,9,11,12,13,14,15,16,17-decahydro-6H-cyclopenta[α]phenanthrene-3,17-diol	642-948-3	153004-31-0	Active	Intermediate	Joint	Intermediate use only	30-11-2021	View substance registered dossier
(7S,8R,9S,13S,14S,17S)-3,17-dihydroxy-13-methyl-7-(9-((4,4,5,5,5-pentafluoropentyl)thio)nonyl)-7,8,9,11,12,13,14,15,16,17-decahydro-6H-cyclopenta[α]phenanthren-6-one	837-287-4	1107606-70-1	Active	Intermediate	Joint	Intermediate use only	30-11-2021	View substance registered dossier
(7S,8R,9S,13S,14S,17S)-7-(9-chlorononyl)-3,17-dihydroxy-13-methyl-7,8,9,11,12,13,14,15,16,17-decahydro-6H-cyclopenta[a]phenanthren-6-one	955-019-5	-	Active	Intermediate	Joint	Intermediate use only	22-10-2021	View substance registered dossier
(7S,9aS)-7-[(benzyloxy)methyl]octahydropyrazino[2,1-c][1,4]oxazine dioxalic acid salt	875-887-8	1268364-46-0	Active	Intermediate	Joint	Intermediate use only	23-02-2022	View substance registered dossier
(8R,9S,10R,13S,14S,17R)-10,13-Dimethyl-1,8,9,10,11,12,13,14,15,16-decahydro-3'H-spiro[cyclopenta[a]phenanthrene-17,2'-furan]-3,5'(2H,4'H)-dione - 2,3,5,6-tetrachlorobenzene-1,4-diol (1:1)	926-987-6	-	Active	Intermediate	Joint	Intermediate use only	13-12-2021	View substance registered dossier
(8R,9S,10R,13S,14S,17R)-17-ethynyl-10,13-dimethyl-1,2,4,7,8,9,10,11,12,13,14,15,16,17,-tetradecahydrospiro[cyclopenta[a]phenanthrene-3,2´-[1,3]dioxolan]-17-ol	610-527-3	50407-76-6	Active	Intermediate	Joint	Intermediate use only	06-05-2020	View substance registered dossier
(8R,9S,10R,13S,14S,17R)-17-ethynyl-17-hydroxy-13-methyl-1,2,8,9,10,11,12,14,15,16-decahydrocyclopenta[a]phenanthren-3-one	608-630-3	31528-46-8	Cease Manufacture	Full	Joint	Cease manufacture	10-01-2019	View substance registered dossier
(8R,9S,13S,14S)-3-(Benzyloxy)-13-methyl-6,7,8,9,11,12,13,14 ,15,16-decahydrospiro[cyclopenta[a]phenanthrene-17,2`-[1,3]dioxolane]	844-245-9	162784-26-1	Active	Intermediate	Individual	Intermediate use only	09-11-2021	View substance registered dossier
(8R,9S,13S,14S)-3-benzyloxy)-13-methyl-6,7,8,9,11,12,13,14- octahydrospiro[cyclopenta[a]phenanthrene-17,2`[1,3]dioxolane]	844-243-8	534572-67-3	Active	Intermediate	Individual	Intermediate use only	05-11-2021	View substance registered dossier
(8R,9S,13S,14S,17S)-3,17-bis((2-methoxypropan-2-yl)oxy)-13-methyl-7,8,9,11,12,13,14,15,16,17-decahydro-6H-cyclopenta[α]phenanthren-6-one	875-633-6	486999-08-0	Active	Intermediate	Joint	Intermediate use only	12-11-2021	View substance registered dossier
(8R,9S,13S,14S,17S)-3,17-dihydroxy-13-methyl-8,9,11,12,14,15,16,17-octahydro-7H-cyclopenta[a]phenanthren-6-one	641-994-1	571-92-6	Active	Intermediate	Joint	Intermediate use only	01-04-2020	View substance registered dossier
(8S,10S,13S,14S,17R)-17-hydroxy-10,13-dimethyl-1,2,4,7,8,10,12,13,14,15,16,17-dodecahydrospiro[cyclopenta[a]phenanthrene-3,2'-[1,3]dioxolane]-17-carbonitrile	601-332-4	114882-16-5	Active	Intermediate	Joint	Intermediate use only	25-01-2022	View substance registered dossier
(8S,13S,14S,17R)-17-allyl-13-methyl-1,2,4,6,7,8,12,13,14,15,16,17-dodecahydrospiro[cyclopenta[a]phenanthrene-3,2'-[1,3]dioxolan]-17ol	849-739-8	141299-95-8	Active	Intermediate	Joint	Intermediate use only	13-04-2021	View substance registered dossier
(8S,13S,14S,17R)-17-allyl-17-hydroxy-13-methyl-1,2,4,6,7,8,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthren-3-one	849-749-2	23760-34-1	Active	Intermediate	Joint	Intermediate use only	13-04-2021	View substance registered dossier
(8S,13S,14S,17S)-17-hydroxy-13-methyl-2,6,7,8,14,15,16,17-octahydro-1H-cyclopenta[a]phenanthren-3-one	600-229-1	10161-33-8	Active	Intermediate	Joint	Intermediate use only	07-02-2022	View substance registered dossier
(8~{S},13~{S},14~{S})-13-methyl-1,2,6,7,8,11,12,14,15,16-decahydrocyclopenta[a]phenanthrene-3,17-dione	610-717-6	5173-46-6	Active	Intermediate	Joint	Intermediate use only	21-02-2019	View substance registered dossier
(8α,9R,8'''α,9'''R)-1,1'-[(2,3,5,6-tetrafluoro-1,4-phenylene)bis(methylene)]bis(6'-methoxycinchonan-1-ium-9-ol) dibromide	857-673-6	1879067-61-4	Active	Full	Joint	≥ 1 to < 10 tonnes	11-08-2022	View substance registered dossier
(9beta,11beta)-3,20-dioxo-9,11-epoxypregna-1,4,16-trien-21-yl acetate	600-439-3	103466-44-0	Active	Intermediate	Joint	Intermediate use only	25-01-2022	View substance registered dossier
(9H-fluoren-9-yl)methyl (2,5-dioxopyrrolidin-1-yl) carbonate	433-520-5	82911-69-1	Active	NONS	Joint	Tonnage data confidential	10-11-2008	View substance registered dossier
(9H-fluoren-9-yl)methyl (2,5-dioxopyrrolidin-1-yl) carbonate	433-520-5	82911-69-1	Active	Intermediate	Joint	Intermediate use only	29-11-2022	View substance registered dossier
(9R,10S,13S)-10,13-dimethyl-17-(2-methyl-1,3-dioxolan-2-yl)spiro[1,2,4,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthrene-3,2'-1,3-dioxolane]	611-207-6	5488-51-7	Active	Intermediate	Joint	Intermediate use only	19-11-2018	View substance registered dossier
(9S)-9-amino-9-deoxyerythromycin E.M.A.	406-790-7	26116-56-3	Active	NONS	Individual	Tonnage data confidential	10-11-2008	View substance registered dossier
(9β,11β,16α)-9,11-epoxy-21-hydroxy-16, 17-[(1-methylethylidene)bis(oxy)]-pregna-1,4-diene-3,20-dione	609-736-2	39672-75-8	Active	Intermediate	Individual	Intermediate use only	30-05-2014	View substance registered dossier
(alpha-cyanobenzyl)malonic acid diethyl ester	922-463-6	-	Active	Intermediate	Joint	Intermediate use only	17-02-2017	View substance registered dossier
(alphaS)-methyl alpha-(2-chlorophenyl)-6,7-dihydrothieno[3,2-c]pyridine-5(4H)-acetate 2-propyl sulfate	614-478-9	684269-94-1	Active	Intermediate	Joint	Intermediate use only	15-09-2021	View substance registered dossier
(aminoalkyl) hydrogen thiosulfate	-	-	Active	Full	Joint	≥ 1 to < 10 tonnes	05-01-2021	View substance registered dossier
(benzoato-O,O')hydroxy(octadecanoato-O,O')aluminium	259-105-7	54326-11-3	Active	Full	Joint	≥ 10 to < 100 tonnes	06-07-2022	View substance registered dossier
(benzothiazol-2-ylthio)acetic acid	228-565-0	6295-57-4	Active	Full	Joint	≥ 100 to < 1 000 tonnes	27-07-2021	View substance registered dossier
(benzothiazol-2-ylthio)succinic acid (2-BENZOTHIAZOLYLTHIO)BERNSTEINSÄURE; BTTBS; HALOX 650; IRGACOR 252	401-450-4	95154-01-1	Active	Full	Joint	≥ 0 to < 10 tonnes	21-12-2021	View substance registered dossier
(benzothiazol-2-ylthio)succinic acid (2-BENZOTHIAZOLYLTHIO)BERNSTEINSÄURE; BTTBS; HALOX 650; IRGACOR 252	401-450-4	95154-01-1	Active	NONS	Joint	Tonnage data confidential	10-11-2008	View substance registered dossier
(benzylamine)trifluoroboron	211-802-7	696-99-1	Active	Full	Joint	≥ 1 to < 10 tonnes	18-05-2018	View substance registered dossier
(Benzyloxycarbonyl)methyl 3-[5-acetamido-4-(2-chloro-4,6-dinitrophenylazo)-2-methoxyanilino]propionate	436-000-6	159010-67-0	Active	Full	Joint	≥ 1 tonnes	20-03-2020	View substance registered dossier
(Benzyloxycarbonyl)methyl 3-[5-acetamido-4-(2-chloro-4,6-dinitrophenylazo)-2-methoxyanilino]propionate	436-000-6	159010-67-0	Cease Manufacture	NONS	Individual	Cease manufacture	10-11-2008	View substance registered dossier
(Benzyloxycarbonyl)methyl 4-(1-Butyl-5-cyano-1,6-dihydro-2-hydroxy-4-methyl-6-oxo-3-pyridylazo)-benzoate	442-520-4	-	Active	Full	Joint	≥ 1 tonnes	12-02-2020	View substance registered dossier
(Benzyloxycarbonyl)methyl 4-(1-Butyl-5-cyano-1,6-dihydro-2-hydroxy-4-methyl-6-oxo-3-pyridylazo)-benzoate	442-520-4	-	Cease Manufacture	NONS	Individual	Cease manufacture	10-11-2008	View substance registered dossier
(Bromomethyl)cyclobutane	700-027-4	17247-58-4	Cease Manufacture	Intermediate	Individual	Cease manufacture	31-08-2011	View substance registered dossier
(Bromomethyl)cyclobutane	700-027-4	17247-58-4	Cease Manufacture	Intermediate	Joint	Cease manufacture	14-12-2011	View substance registered dossier
(Bromomethylphenyl-4')-2 benzonitrile	601-327-7	114772-54-2	Active	Intermediate	Joint	Intermediate use only	31-05-2013	View substance registered dossier
(butylamine)[[2,2'-thiobis[4-(1,1,3,3-tetramethylbutyl)phenolato]](2-)-O,O',S]nickel	238-523-3	14516-71-3	Active	Full	Joint	≥ 100 to < 1 000 tonnes	28-09-2022	View substance registered dossier

Showing 901 - 1,000 of 26,866 results.

Registrant/Supplier	Address	Country	Registration Status	Name	EC / List no.	CAS no.	Last update year	Details
Industriale Chimica s.r.l.	via E.H. Grieg, 13 21074 Saronno (VA) Italy	Italy	Active	(6ALPHA,11BETA,16ALPHA,17ALPHA)-6,9-DIFLUORO-11-HYDRO XY-16-METHYL-3-OXO-17- (1-OXOPROPOXY)ANDROSTA-1,4-DIENE-CARBOTHIOIC ACID	617-084-5	80474-45-9	-	View substance registered dossier
EUROAPI Germany GmbH	Brüningstraße 50 65926 Frankfurt am Main Germany	Germany	Active	(6R)-6-(dimethylamino)-4,4-diphenylheptan-3-one	603-081-6	125-58-6	2022	View substance registered dossier
EUROAPI Germany GmbH	Brüningstraße 50 65926 Frankfurt am Main Germany	Germany	Active	(6R)-6-Dimethylamino-4,4-diphenyl-heptan-3-one; compound with 2-(toluene-4-sulfonylamino)-pentanedioic acid	921-925-4	-	2022	View substance registered dossier
F.I.S. Fabbrica Italiana Sintetici S.p.a.	Viale Milano, 26 36075 Montecchio Maggiore (VI) Veneto Italy	Italy	Active	(6R,7R)-7-hydroxy-6-[(propan-2-yl)amino]-4,5,6,7-tetrahydroimidazo[4,5,1-jk][1]benzazepin-2(1H)-one	862-404-0	119520-05-7	-	View substance registered dossier
Corden Pharma Latina S.p.A.	Via Murillo, 7 IT04013 Sermoneta (LT) Lazio Italy	Italy	Cease Manufacture	(6R,7R)-3-[(5-amino-4-{[(2-aminoethyl)carbamoyl]amino}-1-methyl-1H-pyrazol-2-ium-2-yl)methyl]-7-{[(2Z)-2-(5-amino-1,2,4-thiadiazol-3-yl)-2-{[(2-carboxypropan-2-yl)oxy]imino}acetyl]amino}-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate trifluoroacetate (1:3)	939-998-6	-	2017	View substance registered dossier
ACS DOBFAR S.p.A	Viale Addetta 4/12 20067 Tribiano Milano Italy	Italy	Active	(6R,7R)-3-[(5-amino-4-{[(2-aminoethyl)carbamoyl]amino}-1-methyl-1H-pyrazol-2-ium-2-yl)methyl]-7-{[(2Z)-2-(5-amino-1,2,4-thiadiazol-3-yl)-2-{[(2-carboxypropan-2-yl)oxy]imino}acetyl]amino}-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate trifluoroacetate (1:3)	939-998-6	-	-	View substance registered dossier
Sandoz GmbH	Biochemiestr. 10 6250 Kundl Austria	Austria	Cease Manufacture	(6R,7R)-3-[[(Aminocarbonyl)oxy]methyl]-7-[[(2Z)-2-furanyl(methoxyimino)acetyl]amino]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-en-2-carboxylic acid, 1-butylammonium salt	439-350-8	-	2021	View substance registered dossier
Corden Pharma Latina S.p.A.	Via Murillo, 7 IT04013 Sermoneta (LT) Lazio Italy	Italy	Active	(6R,7R)-3-chloromethyl-7-{(Z)-2-(5-amino-1,2,4-thiadiazol-3-yl)2-[(1-carboxy-1-methylethoxy)imino]acetylamino}-8-oxo-5-thia-1-azbicyclo[4.2.0]oct-2-ene-2-carboxylic acid p-methoxybenzyl ester	939-996-5	689294-28-8	-	View substance registered dossier
ACS DOBFAR S.p.A	Viale Addetta 4/12 20067 Tribiano Milano Italy	Italy	Active	(6R,7R)-3-chloromethyl-7-{(Z)-2-(5-amino-1,2,4-thiadiazol-3-yl)2-[(1-carboxy-1-methylethoxy)imino]acetylamino}-8-oxo-5-thia-1-azbicyclo[4.2.0]oct-2-ene-2-carboxylic acid p-methoxybenzyl ester	939-996-5	689294-28-8	2014	View substance registered dossier
Glaxo Operations UK	Glaxo Wellcome House Berkeley Avenue UB6 0NN Greenford Middlesex United Kingdom	United Kingdom	No longer Valid	(6R,7R)-7-[((2Z)-2-[({2-[(1,1-dimethylethyl)oxy]-1,1-dimethyl-2-oxoethyl}oxy)imino]-2-{2-[(triphenylmethyl)amino]-1,3-thiazol-4-yl}acetyl)amino]-8-oxo-3-(1-pyridiniumylmethyl)-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate	617-560-2	84377-83-3	2021	View substance registered dossier
FRESENIUS KABI iPSUM s.r.l.	Via Roma, 108 20060 Cassina de' Pecchi (MI) Italy	Italy	Active	(6R,7R)-7-[[(2Z)-(2-Aminothiazol-4-yl)(methoxy-imino)acetyl]amino]-3-[1-methylpyrrolidinio)methyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate dihydrochloride	827-945-9	107648-80-6	-	View substance registered dossier
FRESENIUS KABI iPSUM s.r.l.	Via Roma, 108 20060 Cassina de' Pecchi (MI) Italy	Italy	Active	(6R,7R)-7-[[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-[2-methyl-1-[(2-methylpropan-2-yl)oxy]-1-oxopropan-2-yl]oxyiminoacetyl]amino]-8-oxo-3-(pyridin-1-ium-1-ylmethyl)-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate	600-349-4	102772-66-7	-	View substance registered dossier
Sandoz GmbH	Biochemiestr. 10 6250 Kundl Austria	Austria	Cease Manufacture	(6R,7R)-7-[[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-[2-methyl-1-[(2-methylpropan-2-yl)oxy]-1-oxopropan-2-yl]oxyiminoacetyl]amino]-8-oxo-3-(pyridin-1-ium-1-ylmethyl)-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate	600-349-4	102772-66-7	2021	View substance registered dossier
ACS DOBFAR S.p.A	Viale Addetta 4/12 20067 Tribiano Milano Italy	Italy	Active	(6R,7R)-7-[[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-[2-methyl-1-[(2-methylpropan-2-yl)oxy]-1-oxopropan-2-yl]oxyiminoacetyl]amino]-8-oxo-3-(pyridin-1-ium-1-ylmethyl)-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate	600-349-4	102772-66-7	-	View substance registered dossier
Sandoz GmbH	Biochemiestr. 10 6250 Kundl Austria	Austria	Cease Manufacture	(6R,7R)-7-[[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-methoxyiminoacetyl]amino]-3-(furan-2-carbonylsulfanylmethyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid;hydrochloride	600-507-2	103980-44-5	2021	View substance registered dossier
OLON Spa	Strada Rivoltana Km 6/7 20053 RODANO Milano Italy	Italy	Active	(6R,7R)-7-[[(2Z)-2-(5-amino-1,2,4-thiadiazol-3-yl)-2-[(triphenylmethoxy)imino]acethyl]amino]-3-(hydroxymethyl)-8-oxo-5thia-1-azabicyclo[4.2.0]oct-2-ene-carboxylic acid diphenylmethyl ester	609-461-8	376653-36-0	2018	View substance registered dossier
OLON Spa	Strada Rivoltana Km 6/7 20053 RODANO Milano Italy	Italy	Active	(6R,7R)-7-[[(2Z)-2-(5-amino-1,2,4-thiadiazol-3-yl)-2-[(triphenylmethoxy)imino]acetyl]amino]-3-[(E)-[(3'R)-1'-[(1,1-dimethylethoxy)carbonyl]-2-oxo-[1,3'-bipyrrolidin]-3-ylidene]methyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid diphenylmethyl ester	609-463-9	376653-41-7	2018	View substance registered dossier
Sandoz GmbH	Biochemiestr. 10 6250 Kundl Austria	Austria	Cease Manufacture	(6R,7R)-7-amino-3-(5H-imidazo[1,2-b]pyridazin-1-ylmethyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid;hydroiodide	606-382-0	197897-11-3	2021	View substance registered dossier
Sandoz GmbH	Biochemiestr. 10 6250 Kundl Austria	Austria	Cease Manufacture	(6R,7R)-7-amino-3-{[(furan-2-ylcarbonyl)sulfanyl]methyl}-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid	617-065-1	80370-59-8	2021	View substance registered dossier
Sandoz GmbH	Biochemiestr. 10 6250 Kundl Austria	Austria	Active	(6R,7R)-7-Amino-8-oxo-3-vinyl-5-thia-1-aza-bicyclo[4,2,0]oct-2-ene-2-carboxylic acid	438-350-5	79349-82-9	2010	View substance registered dossier
OLON Spa	Strada Rivoltana Km 6/7 20053 RODANO Milano Italy	Italy	Active	(6R,7R)-7-Amino-8-oxo-3-vinyl-5-thia-1-aza-bicyclo[4,2,0]oct-2-ene-2-carboxylic acid	438-350-5	79349-82-9	2012; 2017	View substance registered dossier
Sandoz GmbH	Biochemiestr. 10 6250 Kundl Austria	Austria	Cease Manufacture	(6R,7R)-7-{[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetyl]amino}-3-({[5-(carboxymethyl)-4-methyl-1,3-thiazol-2-yl]sulfanyl}methyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid	700-301-3	69739-16-8	2021	View substance registered dossier
ACS DOBFAR S.p.A	Viale Addetta 4/12 20067 Tribiano Milano Italy	Italy	Active	(6R,7R)-benzhydryl 3-hydroxy-8-oxo-7-(2-phenylacetamido)-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate	611-177-4	54639-48-4	2013	View substance registered dossier
Sandoz GmbH	Biochemiestr. 10 6250 Kundl Austria	Austria	Cease Manufacture	(6R,7R)-benzhydryl 3-hydroxy-8-oxo-7-(2-phenylacetamido)-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate	611-177-4	54639-48-4	2021	View substance registered dossier
Teva Czech Industries s.r.o.	Ostravska 29/305 74770 Opava - Komarov Czech Republic	Czech Republic	Active	(6R,7R,14S)-17-cyano-7,8-dihydro-7-[(1S)-1-hydroxy-1,2,2-trimethylpropyl]-3,6-O-dimethyl-6,14-ethano-17-normorphine	921-415-1	-	-	View substance registered dossier
Teva Czech Industries s.r.o.	Ostravska 29/305 74770 Opava - Komarov Czech Republic	Czech Republic	Active	(6R,7R,14S)-7,8-dihydro-7-[(1S)-1-hydroxy-1,2,2-trimethylpropyl]-3,6-O-dimethyl-6,14-ethanomorphine	918-453-6	-	-	View substance registered dossier
Teva Czech Industries s.r.o.	Ostravska 29/305 74770 Opava - Komarov Czech Republic	Czech Republic	Active	(6R,7R,14S)-7,8-dihydro-7-[(1S)-1-hydroxy-1,2,2-trimethylpropyl]-6-O-methyl-6,14-ethano-17-normorphine	917-585-1	-	-	View substance registered dossier
ACS DOBFAR S.p.A	Viale Addetta 4/12 20067 Tribiano Milano Italy	Italy	Active	(6R,7S)-Benzhydryl 7-amino-7-methoxy-3-((1-methyl-1H-tetrazol-5-ylthio)methyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate	611-404-7	56610-72-1	-	View substance registered dossier
Sandoz GmbH	Biochemiestr. 10 6250 Kundl Austria	Austria	Cease Manufacture	(6R-trans)-1-((7-Ammonio-2-carboxylato-8-oxo-5-thia-1-azabicyclo-(4.2.0)oct-2-en-3-yl)methyl)pyridinium iodide	423-260-0	100988-63-4	2021	View substance registered dossier
ACS DOBFAR S.p.A	Viale Addetta 4/12 20067 Tribiano Milano Italy	Italy	Active	(6R-trans)-7-amino-3-(hydroxymethyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid	239-787-2	15690-38-7	-	View substance registered dossier
Sandoz GmbH	Biochemiestr. 10 6250 Kundl Austria	Austria	Cease Manufacture	(6R-trans)-7-amino-3-(hydroxymethyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid	239-787-2	15690-38-7	2021	View substance registered dossier
Sanofi Aventis Deutschland GmbH	Industriepark Höchst H 831 (Room A0472) z.Hd. Hr. Dr. Schwind 65926 Frankfurt am Main Germany	Germany	Active	(6R-trans)-7-amino-3-[([5-(carboxymethyl)-4-methyl-2-thiazolyl]thio)methyl]-8-oxo- 5-thia-1-azabicyclo-[4.2.0]oct-2-en-2-carboxylic acid	403-690-5	111298-82-9	-	View substance registered dossier
ACS DOBFAR S.p.A	Viale Addetta 4/12 20067 Tribiano Milano Italy	Italy	Active	(6R-trans)-7-amino-3-[[(5-methyl-1,3,4-thiadiazol-2-yl)thio]methyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid	250-099-1	30246-33-4	2019	View substance registered dossier
Sandoz GmbH	Biochemiestr. 10 6250 Kundl Austria	Austria	Cease Manufacture	(6R-trans)-7-amino-3-[[[5-(carboxymethyl)-4-methyl-2-thiazolyl]thio]methyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid	619-847-8	111298-82-9	2021	View substance registered dossier
ACS DOBFAR S.p.A	Viale Addetta 4/12 20067 Tribiano Milano Italy	Italy	Active	(6R-trans)-7-amino-3-chloro-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid	258-907-4	53994-69-7	2019	View substance registered dossier
Centrient Pharmaceuticals Netherlands B.V.	Alexander Fleminglaan 1 2613 AX Delft Netherlands	Netherlands	Active	(6R-trans)-7-amino-3-methyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid	244-870-1	22252-43-3	-	View substance registered dossier
ACS DOBFAR S.p.A	Viale Addetta 4/12 20067 Tribiano Milano Italy	Italy	Active	(6R-trans)-7-amino-3-methyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid	244-870-1	22252-43-3	-	View substance registered dossier
ACS DOBFAR S.p.A	Viale Addetta 4/12 20067 Tribiano Milano Italy	Italy	Active	(6R-trans)-7-amino-8-oxo-3-[[(1,2,5,6-tetrahydro-2-methyl-5,6-dioxo-1,2,4-triazin-3-yl)thio]methyl]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid	261-491-7	58909-56-1	-	View substance registered dossier
Sandoz GmbH	Biochemiestr. 10 6250 Kundl Austria	Austria	Cease Manufacture	(6R-trans)-7-amino-8-oxo-3-[[(1,2,5,6-tetrahydro-2-methyl-5,6-dioxo-1,2,4-triazin-3-yl)thio]methyl]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid	261-491-7	58909-56-1	2020	View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant UK competent national authority.	-	-	Active	(6RS,7RS)3,5,5,6,7,8,8-heptamethyl-5,6,7,8-tetrahydronaphthalene-2-carbaldehyde	482-190-9	127459-79-4	-	View substance registered dossier
-	-	-	-	(6RS,7RS)3,5,5,6,7,8,8-heptamethyl-5,6,7,8-tetrahydronaphthalene-2-carbaldehyde	482-190-9	127459-79-4	-	View substance registered dossier
AbbVie Logistics B.V.	Zuiderzeelaan 53 8017 JV Zwolle Netherlands	Netherlands	Active	(6S)-1'-tert-butyl-3-chlorospiro[5,7-dihydrocyclopenta[b]pyridine-6,3'-pyrrolo[2,3-b]pyridine]-2'-one	881-148-0	1455358-14-1	2022	View substance registered dossier
TAKASAGO TICSA-Producer/Importer	Avenida de Mazarrón, 49 30120 El Palmar Murcia Spain	Spain	Active	(6S)-2,6-dimethyloct-2-ene-8,8-diyl diacetate	949-377-1	-	-	View substance registered dossier
Avara Shannon Pharmaceutical Services Limited	Shannon Industrial Estate V14 FX09 Shannon Clare Ireland	Ireland	Cease Manufacture	(6S)-6-(propylamino)-5,6,7,8-tetrahydronaphthalen-1-ol hydrobromide (1:1)	605-420-3	165950-84-5	2021	View substance registered dossier
Cambrex Karlskoga AB	Bjorkborns Industriomrade 69185 Karlskoga Sweden	Sweden	Active	(6S)-6-(propylamino)-5,6,7,8-tetrahydronaphthalen-1-ol hydrobromide (1:1)	605-420-3	165950-84-5	2018; 2020	View substance registered dossier
F.I.S. Fabbrica Italiana Sintetici S.p.a.	Viale Milano, 26 36075 Montecchio Maggiore (VI) Veneto Italy	Italy	Active	(6S)-6-methyl-5,6-Dihydro-4H-thieno[2,3-b]thiopyran4-one-7,7-dioxide	431-140-4	-	-	View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant UK competent national authority.	-	-	Active	(6S)-6-methyl-5,6-Dihydro-4H-thieno[2,3-b]thiopyran4-one-7,7-dioxide	431-140-4	-	-	View substance registered dossier
Avara Shannon Pharmaceutical Services Limited	Shannon Industrial Estate V14 FX09 Shannon Clare Ireland	Ireland	Cease Manufacture	(6S)-6-{propyl[2-(2-thienyl)ethyl]amino}-5,6,7,8-tetrahydronaphthalen-1-ol hydrochloride (1:1)	603-080-0	125572-93-2	2021	View substance registered dossier
Cambrex Karlskoga AB	Bjorkborns Industriomrade 69185 Karlskoga Sweden	Sweden	Active	(6S)-6-{propyl[2-(2-thienyl)ethyl]amino}-5,6,7,8-tetrahydronaphthalen-1-ol hydrochloride (1:1)	603-080-0	125572-93-2	2019; 2020	View substance registered dossier
F.I.S. Fabbrica Italiana Sintetici S.p.a.	Viale Milano, 26 36075 Montecchio Maggiore (VI) Veneto Italy	Italy	Active	(6S,12aR)-3,10-Dibromo-12,12a-dihydro-6-phenyl-6H-indolo[1,2-c][1,3]benzoxazine	813-155-1	1585969-16-9	-	View substance registered dossier
Sandoz GmbH	Biochemiestr. 10 6250 Kundl Austria	Austria	Cease Manufacture	(6S,7S)-7-Amino-3-(methoxymethyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid	435-680-1	-	2021	View substance registered dossier
EUROAPI FRANCE	15 rue Traversière 75012 Paris France	France	Active	(6S,8S,9S,10R,11S,13S,14S,17R)-17-acetyl-11,17-dihydroxy-6,10,13-trimethyl-2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthren-3-one	615-123-0	7055-53-0	2021; 2022	View substance registered dossier
Industriale Chimica s.r.l.	via E.H. Grieg, 13 21074 Saronno (VA) Italy	Italy	Active	(6S,9R,10S,11S,13S,14S,16R,17R)-17-(((diethylamino)(ethyl)-λ4-sulfaneyl)carbonyl)-6,9-difluoro-11-hydroxy-10,13,16-trimethyl-3-oxo-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[α]phenanthren-17-yl propionate	884-371-1	577970-31-1	-	View substance registered dossier
Industriale Chimica s.r.l.	via E.H. Grieg, 13 21074 Saronno (VA) Italy	Italy	Active	(6S,9R,10S,11S,13S,14S,16R,17R)-6,9-difluoro-11-hydroxy-10,13,16-trimethyl-3-oxo-17-(propionyloxy)-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthrene-17-carboxylic acid	813-979-1	65429-42-7	-	View substance registered dossier
[Confidential]	-	-	-	(6S,9R,10S,11S,13S,16R,17R)-6,9-difluoro-11,17-dihydroxy-10,13,16-trimethyl-3-oxo-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthrene-17-carboxylic acid	434-320-0	-	-	View substance registered dossier
HH Compliance Ltd	Rubicon Building CIT Campus T12 Y275 Bishopstown Cork Ireland	Ireland	Cease Manufacture	(6S,9R,10S,11S,13S,16R,17R)-6,9-difluoro-11,17-dihydroxy-10,13,16-trimethyl-3-oxo-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthrene-17-carboxylic acid	434-320-0	-	2023	View substance registered dossier
Industriale Chimica s.r.l.	via E.H. Grieg, 13 21074 Saronno (VA) Italy	Italy	Active	(6S,9R,10S,11S,13S,16R,17R)-6,9-difluoro-11,17-dihydroxy-10,13,16-trimethyl-3-oxo-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthrene-17-carboxylic acid	434-320-0	-	-	View substance registered dossier
F.I.S. Fabbrica Italiana Sintetici S.p.a.	Viale Milano, 26 36075 Montecchio Maggiore (VI) Veneto Italy	Italy	Active	(6Z)-6-(hydroxyimino)-5,6-dihydroimidazo[4,5,1-jk][1]benzazepine-2,7(1H,4H)-dione	695-945-4	-	-	View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant Dutch competent national authority.	-	-	Active	(6β)-6,19-epoxyandrost-4-ene-3,17-dione	433-490-3	6563-83-3	-	View substance registered dossier
Cambrex Karlskoga AB	Bjorkborns Industriomrade 69185 Karlskoga Sweden	Sweden	Active	(7-Bromobenzofuran-5-yl)methanol	876-095-5	286836-24-6	-	View substance registered dossier
Sensient Colors	Oldmedow Road PE30 4LA King's Lynn Norfolk United Kingdom	United Kingdom	No longer Valid	(7-Hydroxy-2-naphthyl)-trimethylammonium methyl sulphate	807-380-4	377734-55-9	2021	View substance registered dossier
LABORATORIOS SERVIER S.L.	RIO JARAMA 59 45007 TOLEDO Spain	Spain	Active	(7-Methoxy-3,4-dihydronaphthalen-1-yl)acetonitrile	617-813-7	861960-34-1	-	View substance registered dossier
EGIS Pharmaceuticals PLC	Keresztúri út 30-38 H-1106 Budapest Hungary	Hungary	Active	(7-Methoxy-3,4-dihydronaphthalen-1-yl)acetonitrile	617-813-7	861960-34-1	-	View substance registered dossier
EGIS Pharmaceuticals PLC	Keresztúri út 30-38 H-1106 Budapest Hungary	Hungary	Active	(7-methoxynaphthalen-1-yl)acetonitrile	461-670-1	-	-	View substance registered dossier
LABORATORIOS SERVIER S.L.	RIO JARAMA 59 45007 TOLEDO Spain	Spain	Active	(7-methoxynaphthalen-1-yl)acetonitrile	461-670-1	-	2011; 2018	View substance registered dossier
EUROAPI Hungary Ltd.	Tó utca 1-5. 1045 Budapest Hungary	Hungary	Active	(7-methoxynaphthalen-1-yl)acetonitrile	461-670-1	-	2021	View substance registered dossier
ORIL INDUSTRIE	13 rue Auguste Desgenétais 76210 BOLBEC France	France	Active	(7-methoxynaphthalen-1-yl)acetonitrile	461-670-1	-	-	View substance registered dossier
Siegfried PharmaChemikalien Minden GmbH	Karlstr. 15-39, 42-44 32423 Minden Nordrhein-Westphalen Germany	Germany	Active	(7-Phenylsulfonyl-6-nitro-chinazolin-4-yl)-(3-chlor-4-fluor-phenyl)-amin	620-069-6	945553-94-6	-	View substance registered dossier
CARBOGEN AMCIS B.V.	Nieuweweg 2a 3901 BE Veenendaal Netherlands	Netherlands	Active	(7-Phenylsulfonyl-6-nitro-chinazolin-4-yl)-(3-chlor-4-fluor-phenyl)-amin	620-069-6	945553-94-6	-	View substance registered dossier
Boehringer Ingelheim Pharma GmbH & Co. KG	Binger Strasse 173 55216 Ingelheim am Rhein Germany	Germany	Active	(7-Phenylsulfonyl-6-nitro-chinazolin-4-yl)-(3-chlor-4-fluor-phenyl)-amin	620-069-6	945553-94-6	-	View substance registered dossier
MSD International GmbH (Ballydine Branch)	Ballydine - Kilsheelan 0 Clonmel Ireland	Ireland	Active	(7R)-4-(5-Chloro-1,3-benzoxazol-2-yl)-7-methyl-1,4-diazepan-1-ium chloride	690-742-7	1266664-66-7	2019; 2020	View substance registered dossier
Centrient Pharmaceuticals Netherlands B.V.	Alexander Fleminglaan 1 2613 AX Delft Netherlands	Netherlands	Cease Manufacture	(7R)-7-(4-carboxybutanamido)cephalosporanate amidohydrolase (enzyme substance)	611-406-8	56645-46-6	2022	View substance registered dossier
N.V. Ajinomoto OmniChem S.A.	Cooppallaan 91 9230 Wetteren Oost-Vlaanderen Belgium	Belgium	Active	(7R,13S,17S)-13-methyl-3-oxo-7-(9-((4,4,5,5,5-pentafluoropentyl)thio)nonyl)-2,3,6,7,8,9,10,11,12,13,14,15,16, 17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl acetate	642-947-8	415927-29-6	-	View substance registered dossier
Minakem High Potent s.a.	Rue Fonds Jean Pâques 8 1435 Mont-Saint-Guibert Belgium	Belgium	Active	(7R,13S,17S)-13-methyl-3-oxo-7-(9-((4,4,5,5,5-pentafluoropentyl)thio)nonyl)-2,3,6,7,8,9,10,11,12,13,14,15,16, 17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl acetate and (7S,13S,17S)-13-methyl-3-oxo-7-(9-((4,4,5,5,5-pentafluoropentyl)thio)nonyl)-2,3,6, 7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl acetate	943-624-7	-	-	View substance registered dossier
STERLING CHEMICAL MALTA LTD.	HF51, Hal-Far Industrial Estate BBG 3000 Birżebbuġa Malta	Malta	Active	(7R,13S,17S)-13-methyl-3-oxo-7-(9-((4,4,5,5,5-pentafluoropentyl)thio)nonyl)-2,3,6,7,8,9,10,11,12,13,14,15,16, 17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl acetate and (7S,13S,17S)-13-methyl-3-oxo-7-(9-((4,4,5,5,5-pentafluoropentyl)thio)nonyl)-2,3,6, 7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl acetate	943-624-7	-	-	View substance registered dossier
N.V. Ajinomoto OmniChem S.A.	Cooppallaan 91 9230 Wetteren Oost-Vlaanderen Belgium	Belgium	Active	(7R,13S,17S)-13-methyl-3-oxo-7-(9-((4,4,5,5,5-pentafluoropentyl)thio)nonyl)-2,3,6,7,8,9,10,11,12,13,14,15,16, 17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl acetate and (7S,13S,17S)-13-methyl-3-oxo-7-(9-((4,4,5,5,5-pentafluoropentyl)thio)nonyl)-2,3,6, 7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl acetate	943-624-7	-	2018	View substance registered dossier
AstraZeneca	Alderley Park AZ SHE Chemical Registration SK10 4TF Macclesfield Cheshire United Kingdom	United Kingdom	No longer Valid	(7R,13S,17S)-13-methyl-3-oxo-7-(9-((4,4,5,5,5-pentafluoropentyl)thio)nonyl)-2,3,6,7,8,9,10,11,12,13,14,15,16, 17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl acetate and (7S,13S,17S)-13-methyl-3-oxo-7-(9-((4,4,5,5,5-pentafluoropentyl)thio)nonyl)-2,3,6, 7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl acetate	943-624-7	-	2021	View substance registered dossier
Industriale Chimica s.r.l.	via E.H. Grieg, 13 21074 Saronno (VA) Italy	Italy	Active	(7R,8R,9S,13S,14S,17S)-13-methyl-7-(9-((4,4,5,5,5-pentafluoropentyl)thio)nonyl)-7,8,9,11,12,13,14,15,16,17-decahydro-6H-cyclopenta[α]phenanthrene-3,17-diol	642-948-3	153004-31-0	-	View substance registered dossier
Industriale Chimica s.r.l.	via E.H. Grieg, 13 21074 Saronno (VA) Italy	Italy	Active	(7S,8R,9S,13S,14S,17S)-3,17-dihydroxy-13-methyl-7-(9-((4,4,5,5,5-pentafluoropentyl)thio)nonyl)-7,8,9,11,12,13,14,15,16,17-decahydro-6H-cyclopenta[α]phenanthren-6-one	837-287-4	1107606-70-1	-	View substance registered dossier
Industriale Chimica s.r.l.	via E.H. Grieg, 13 21074 Saronno (VA) Italy	Italy	Active	(7S,8R,9S,13S,14S,17S)-7-(9-chlorononyl)-3,17-dihydroxy-13-methyl-7,8,9,11,12,13,14,15,16,17-decahydro-6H-cyclopenta[a]phenanthren-6-one	955-019-5	-	-	View substance registered dossier
Bayer AG	Kaiser-Wilhelm-Allee 1 51373 Leverkusen Germany	Germany	Active	(7S,9aS)-7-[(benzyloxy)methyl]octahydropyrazino[2,1-c][1,4]oxazine dioxalic acid salt	875-887-8	1268364-46-0	-	View substance registered dossier
Gedeon Richter Plc.	Gyomroi ut 19-21 1103 Budapest Hungary	Hungary	Active	(8R,9S,10R,13S,14S,17R)-10,13-Dimethyl-1,8,9,10,11,12,13,14,15,16-decahydro-3'H-spiro[cyclopenta[a]phenanthrene-17,2'-furan]-3,5'(2H,4'H)-dione - 2,3,5,6-tetrachlorobenzene-1,4-diol (1:1)	926-987-6	-	2021	View substance registered dossier
Gedeon Richter Plc.	Gyomroi ut 19-21 1103 Budapest Hungary	Hungary	Active	(8R,9S,10R,13S,14S,17R)-17-ethynyl-10,13-dimethyl-1,2,4,7,8,9,10,11,12,13,14,15,16,17,-tetradecahydrospiro[cyclopenta[a]phenanthrene-3,2´-[1,3]dioxolan]-17-ol	610-527-3	50407-76-6	2020	View substance registered dossier
Aspen Oss BV	Kloosterstraat 6 5349 AB Oss Netherlands	Netherlands	Cease Manufacture	(8R,9S,10R,13S,14S,17R)-17-ethynyl-17-hydroxy-13-methyl-1,2,8,9,10,11,12,14,15,16-decahydrocyclopenta[a]phenanthren-3-one	608-630-3	31528-46-8	2022	View substance registered dossier
Gedeon Richter Plc.	Gyomroi ut 19-21 1103 Budapest Hungary	Hungary	Active	(8R,9S,13S,14S)-3-(Benzyloxy)-13-methyl-6,7,8,9,11,12,13,14 ,15,16-decahydrospiro[cyclopenta[a]phenanthrene-17,2`-[1,3]dioxolane]	844-245-9	162784-26-1	-	View substance registered dossier
Gedeon Richter Plc.	Gyomroi ut 19-21 1103 Budapest Hungary	Hungary	Active	(8R,9S,13S,14S)-3-benzyloxy)-13-methyl-6,7,8,9,11,12,13,14- octahydrospiro[cyclopenta[a]phenanthrene-17,2`[1,3]dioxolane]	844-243-8	534572-67-3	-	View substance registered dossier
Industriale Chimica s.r.l.	via E.H. Grieg, 13 21074 Saronno (VA) Italy	Italy	Active	(8R,9S,13S,14S,17S)-3,17-bis((2-methoxypropan-2-yl)oxy)-13-methyl-7,8,9,11,12,13,14,15,16,17-decahydro-6H-cyclopenta[α]phenanthren-6-one	875-633-6	486999-08-0	-	View substance registered dossier
Industriale Chimica s.r.l.	via E.H. Grieg, 13 21074 Saronno (VA) Italy	Italy	Active	(8R,9S,13S,14S,17S)-3,17-dihydroxy-13-methyl-8,9,11,12,14,15,16,17-octahydro-7H-cyclopenta[a]phenanthren-6-one	641-994-1	571-92-6	-	View substance registered dossier
[Confidential]	-	-	-	(8S,10S,13S,14S,17R)-17-hydroxy-10,13-dimethyl-1,2,4,7,8,10,12,13,14,15,16,17-dodecahydrospiro[cyclopenta[a]phenanthrene-3,2'-[1,3]dioxolane]-17-carbonitrile	601-332-4	114882-16-5	-	View substance registered dossier
CHEMO BIOSYNTHESIS SRL	VIALE ISONZO, 8 20135 MILANO Italy	Italy	Active	(8S,13S,14S,17R)-17-allyl-13-methyl-1,2,4,6,7,8,12,13,14,15,16,17-dodecahydrospiro[cyclopenta[a]phenanthrene-3,2'-[1,3]dioxolan]-17ol	849-739-8	141299-95-8	-	View substance registered dossier
Industriale Chimica s.r.l.	via E.H. Grieg, 13 21074 Saronno (VA) Italy	Italy	Active	(8S,13S,14S,17R)-17-allyl-13-methyl-1,2,4,6,7,8,12,13,14,15,16,17-dodecahydrospiro[cyclopenta[a]phenanthrene-3,2'-[1,3]dioxolan]-17ol	849-739-8	141299-95-8	-	View substance registered dossier
CHEMO BIOSYNTHESIS SRL	VIALE ISONZO, 8 20135 MILANO Italy	Italy	Active	(8S,13S,14S,17R)-17-allyl-17-hydroxy-13-methyl-1,2,4,6,7,8,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthren-3-one	849-749-2	23760-34-1	-	View substance registered dossier
Industriale Chimica s.r.l.	via E.H. Grieg, 13 21074 Saronno (VA) Italy	Italy	Active	(8S,13S,14S,17R)-17-allyl-17-hydroxy-13-methyl-1,2,4,6,7,8,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthren-3-one	849-749-2	23760-34-1	-	View substance registered dossier
EUROAPI FRANCE	15 rue Traversière 75012 Paris France	France	Active	(8S,13S,14S,17S)-17-hydroxy-13-methyl-2,6,7,8,14,15,16,17-octahydro-1H-cyclopenta[a]phenanthren-3-one	600-229-1	10161-33-8	2022	View substance registered dossier
Aceto France SAS	3 Rue de Genève CS 50363 BP 50367 Lyon Cedex 06 France	France	Active	(8~{S},13~{S},14~{S})-13-methyl-1,2,6,7,8,11,12,14,15,16-decahydrocyclopenta[a]phenanthrene-3,17-dione	610-717-6	5173-46-6	2019	View substance registered dossier
SAFIC ALCAN	13 Cours Valmy 92977 Paris La Défense France	France	Active	(8~{S},13~{S},14~{S})-13-methyl-1,2,6,7,8,11,12,14,15,16-decahydrocyclopenta[a]phenanthrene-3,17-dione	610-717-6	5173-46-6	-	View substance registered dossier
Syngenta Hellas Single Member S.A.C.I.	Anthousas Avenue 153 49 Anthousa - Attiki Greece	Greece	Active	(8α,9R,8'''α,9'''R)-1,1'-[(2,3,5,6-tetrafluoro-1,4-phenylene)bis(methylene)]bis(6'-methoxycinchonan-1-ium-9-ol) dibromide	857-673-6	1879067-61-4	-	View substance registered dossier
EUROAPI FRANCE	15 rue Traversière 75012 Paris France	France	Active	(9beta,11beta)-3,20-dioxo-9,11-epoxypregna-1,4,16-trien-21-yl acetate	600-439-3	103466-44-0	2021; 2022	View substance registered dossier
Farmabios Spa	Via Pavia, 1 27027 Gropello Cairoli PV Italy	Italy	Active	(9beta,11beta)-3,20-dioxo-9,11-epoxypregna-1,4,16-trien-21-yl acetate	600-439-3	103466-44-0	2017	View substance registered dossier
F.I.S. Fabbrica Italiana Sintetici S.p.a.	Viale Milano, 26 36075 Montecchio Maggiore (VI) Veneto Italy	Italy	Active	(9H-fluoren-9-yl)methyl (2,5-dioxopyrrolidin-1-yl) carbonate	433-520-5	82911-69-1	-	View substance registered dossier
MinAscent Leuna Production GmbH	Am Haupttor Gebäude 4208 06237 Leuna Germany	Germany	Cease Manufacture	(9H-fluoren-9-yl)methyl (2,5-dioxopyrrolidin-1-yl) carbonate	433-520-5	82911-69-1	2019	View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant German competent national authority.	-	-	Active	(9H-fluoren-9-yl)methyl (2,5-dioxopyrrolidin-1-yl) carbonate	433-520-5	82911-69-1	-	View substance registered dossier
CU Chemie Uetikon GmbH	Raiffeisenstrasse 4 77933 Lahr Baden-Württemberg Germany	Germany	Active	(9H-fluoren-9-yl)methyl (2,5-dioxopyrrolidin-1-yl) carbonate	433-520-5	82911-69-1	-	View substance registered dossier
REACH24H CONSULTING GROUP	Suite 1E, Paramount Court, Corrig Road, Sandyford Dublin 18 Dublin Ireland	Ireland	Active	(9H-fluoren-9-yl)methyl (2,5-dioxopyrrolidin-1-yl) carbonate	433-520-5	82911-69-1	-	View substance registered dossier
Roche Pharma AG (1)	Emil-Barell-Strasse 1 79639 Grenzach-Wyhlen Germany	Germany	Active	(9H-fluoren-9-yl)methyl (2,5-dioxopyrrolidin-1-yl) carbonate	433-520-5	82911-69-1	2010; 2013; 2020; 2022	View substance registered dossier
Flamma S.p.a.	via Bedeschi, 22 24040 Chignolo d'Isola Bergamo Italy	Italy	Active	(9H-fluoren-9-yl)methyl (2,5-dioxopyrrolidin-1-yl) carbonate	433-520-5	82911-69-1	-	View substance registered dossier
Chemical and Biopharmaceutical Laboratories of Patras S.A.	Industrial area of Patras, Building block 1 25018 Patras Greece	Greece	Active	(9H-fluoren-9-yl)methyl (2,5-dioxopyrrolidin-1-yl) carbonate	433-520-5	82911-69-1	-	View substance registered dossier
ABBOTT HEALTHCARE PRODUCTS B.V.	C.J. VAN HOUTENLAAN 36 1381CP WEESP Netherlands	Netherlands	Active	(9R,10S,13S)-10,13-dimethyl-17-(2-methyl-1,3-dioxolan-2-yl)spiro[1,2,4,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthrene-3,2'-1,3-dioxolane]	611-207-6	5488-51-7	2018	View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant Irish competent national authority.	-	-	Active	(9S)-9-amino-9-deoxyerythromycin	406-790-7	26116-56-3	-	View substance registered dossier
Sicor - Società Italiana Corticosteroidi S.r.l.	Piazzale Luigi Cadorna 4 20123 Milano (MI) Italy	Italy	Active	(9β,11β,16α)-9,11-epoxy-21-hydroxy-16, 17-[(1-methylethylidene)bis(oxy)]-pregna-1,4-diene-3,20-dione	609-736-2	39672-75-8	-	View substance registered dossier
JSC "Olainfarm"	Rupnicu str. 5 LV-2114 Olaine Latvia	Latvia	Active	(alpha-cyanobenzyl)malonic acid diethyl ester	922-463-6	-	-	View substance registered dossier
Krka, d. d., Novo mesto	Smarjeska cesta 6 SI-8501 Novo mesto Slovenia	Slovenia	Active	(alphaS)-methyl alpha-(2-chlorophenyl)-6,7-dihydrothieno[3,2-c]pyridine-5(4H)-acetate 2-propyl sulfate	614-478-9	684269-94-1	2021	View substance registered dossier
RSI ChemRep Europe Ltd (S001)	27-30 Merchants Quay Merchants House 8 Dublin Ireland	Ireland	Active	(aminoalkyl) hydrogen thiosulfate	-	-	2017; 2021	View substance registered dossier
ILCO INDUSTRIALE S.r.l.	Via fratelli Rosselli, 2 I-20090 Premenugo di Settala - MILAN Italy	Italy	Cease Manufacture	(benzoato-O,O')hydroxy(octadecanoato-O,O')aluminium	259-105-7	54326-11-3	2021	View substance registered dossier
HH Compliance Ltd.	Rubicon-Building, CIT-Campus Bishopstown none Cork Cork Ireland	Ireland	Active	(benzoato-O,O')hydroxy(octadecanoato-O,O')aluminium	259-105-7	54326-11-3	-	View substance registered dossier
Quaker Houghton B.V.	Industrieweg 7 1422 AH Uithoorn Netherlands	Netherlands	Active	(benzoato-O,O')hydroxy(octadecanoato-O,O')aluminium	259-105-7	54326-11-3	-	View substance registered dossier
Specialty Electronic Materials Belgium SRL OR-1	Boulevard d’Angleterre 2 1420 Braine-l’Alleud Belgium	Belgium	Active	(benzoato-O,O')hydroxy(octadecanoato-O,O')aluminium	259-105-7	54326-11-3	-	View substance registered dossier
KAJO GmbH	Boschstr. 13 59609 Anröchte Nordrhein-Westfalen Germany	Germany	Active	(benzoato-O,O')hydroxy(octadecanoato-O,O')aluminium	259-105-7	54326-11-3	-	View substance registered dossier
Archroma Germany GmbH	Kasteler Str. 45 65203 Wiesbaden Germany	Germany	Active	(benzothiazol-2-ylthio)acetic acid	228-565-0	6295-57-4	-	View substance registered dossier
Tecnofluid Srl	Via Mons. Colombo 34 21053 Castellanza VA Italy	Italy	Active	(benzothiazol-2-ylthio)acetic acid	228-565-0	6295-57-4	-	View substance registered dossier
Clariant Prodotti (Italia) S.p.A.	Via Vittor Pisani 20 IT-20124 Milano Italy	Italy	Active	(benzothiazol-2-ylthio)acetic acid	228-565-0	6295-57-4	2021	View substance registered dossier
BASF SE	Carl-Bosch-Str. 38 67056 Ludwigshafen am Rhein Rheinland-Pfalz Germany	Germany	Active	(benzothiazol-2-ylthio)acetic acid	228-565-0	6295-57-4	2021	View substance registered dossier
Clariant Produkte (Deutschland) GmbH	August-Laubenheimer-Straße 1 Global Product Stewardship 65929 Frankfurt am Main Germany	Germany	Active	(benzothiazol-2-ylthio)acetic acid	228-565-0	6295-57-4	2020	View substance registered dossier
Evonik Operations GmbH-M04	Rellinghauser Straße 1-11 45128 Essen Germany	Germany	Active	(benzothiazol-2-ylthio)succinic acid	401-450-4	95154-01-1	2021	View substance registered dossier
Evonik Chemicals Limited	Clayton Lane M11 4SR Clayton Manchester United Kingdom	United Kingdom	No longer Valid	(benzothiazol-2-ylthio)succinic acid	401-450-4	95154-01-1	2021	View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant Danish competent national authority.	-	-	No longer Valid	(benzothiazol-2-ylthio)succinic acid	401-450-4	95154-01-1	2022	View substance registered dossier
ICL Europe Coöperatief U.A.	Prinsenhof Building Koningin Wilhelminaplein 30 1062 KR Amsterdam NH Netherlands	Netherlands	Active	(benzothiazol-2-ylthio)succinic acid	401-450-4	95154-01-1	-	View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant German competent national authority.	-	-	No longer Valid	(benzothiazol-2-ylthio)succinic acid	401-450-4	95154-01-1	2022	View substance registered dossier
Wacker Chemie AG	Hanns-Seidel-Platz 4 81737 Muenchen Germany	Germany	Cease Manufacture	(benzothiazol-2-ylthio)succinic acid	401-450-4	95154-01-1	2022	View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant Belgian competent national authority.	-	-	No longer Valid	(benzothiazol-2-ylthio)succinic acid	401-450-4	95154-01-1	2022	View substance registered dossier
Lanxess Deutschland GmbH	Kennedyplatz 1 50569 Köln Germany	Germany	Active	(benzylamine)trifluoroboron	211-802-7	696-99-1	2017	View substance registered dossier
Laborchemie Apolda GmbH	Utenbacher Straße 72-74 99510 Apolda Germany	Germany	Active	(benzylamine)trifluoroboron	211-802-7	696-99-1	-	View substance registered dossier
ARCHROMA IBÉRICA, S.L.	ZAL-Prat c/Cal Coracero, 46-56 08820 El Prat de Llobregat Spain	Spain	Active	(Benzyloxycarbonyl)methyl 3-[5-acetamido-4-(2-chloro-4,6-dinitrophenylazo)-2-methoxyanilino]propionate	436-000-6	159010-67-0	2014; 2020	View substance registered dossier
Archroma Germany GmbH	Kasteler Str. 45 65203 Wiesbaden Germany	Germany	Active	(Benzyloxycarbonyl)methyl 3-[5-acetamido-4-(2-chloro-4,6-dinitrophenylazo)-2-methoxyanilino]propionate	436-000-6	159010-67-0	2020	View substance registered dossier
Archroma Ibérica, S.L. - OR	ZAL-Prat c/Cal Coracero, 46-56 08820 El Prat de Llobregat Spain	Spain	Cease Manufacture	(Benzyloxycarbonyl)methyl 3-[5-acetamido-4-(2-chloro-4,6-dinitrophenylazo)-2-methoxyanilino]propionate	436-000-6	159010-67-0	2020	View substance registered dossier
Archroma Italy, S.r.l. - OR	Via Manzoni 37 20030 Palazzolo Milanese Italy	Italy	Cease Manufacture	(Benzyloxycarbonyl)methyl 3-[5-acetamido-4-(2-chloro-4,6-dinitrophenylazo)-2-methoxyanilino]propionate	436-000-6	159010-67-0	2017	View substance registered dossier
ARCHROMA IBÉRICA, S.L.	ZAL-Prat c/Cal Coracero, 46-56 08820 El Prat de Llobregat Spain	Spain	Active	(Benzyloxycarbonyl)methyl 4-(1-Butyl-5-cyano-1,6-dihydro-2-hydroxy-4-methyl-6-oxo-3-pyridylazo)-benzoate	442-520-4	-	2020	View substance registered dossier
Archroma Ibérica, S.L. - OR	ZAL-Prat c/Cal Coracero, 46-56 08820 El Prat de Llobregat Spain	Spain	Cease Manufacture	(Benzyloxycarbonyl)methyl 4-(1-Butyl-5-cyano-1,6-dihydro-2-hydroxy-4-methyl-6-oxo-3-pyridylazo)-benzoate	442-520-4	-	2020	View substance registered dossier
Archroma Italy, S.r.l. - OR	Via Manzoni 37 20030 Palazzolo Milanese Italy	Italy	Cease Manufacture	(Benzyloxycarbonyl)methyl 4-(1-Butyl-5-cyano-1,6-dihydro-2-hydroxy-4-methyl-6-oxo-3-pyridylazo)-benzoate	442-520-4	-	2017	View substance registered dossier
MINAKEM Beuvry Production SAS	145, Chemin des Lilas 59310 Beuvry-la-Forêt France	France	Cease Manufacture	(Bromomethyl)cyclobutane	700-027-4	17247-58-4	2015	View substance registered dossier
Evonik Operations GmbH	Rellinghauser Straße 1-11 45128 Essen Germany	Germany	Cease Manufacture	(Bromomethyl)cyclobutane	700-027-4	17247-58-4	2018	View substance registered dossier
EUROAPI Hungary Ltd.	Tó utca 1-5. 1045 Budapest Hungary	Hungary	Active	(Bromomethylphenyl-4')-2 benzonitrile	601-327-7	114772-54-2	-	View substance registered dossier
PLASTIKA KRITIS S.A.	P.O. Box 1093 71110 Heraklion Crete Greece	Greece	Active	(butylamine)[[2,2'-thiobis[4-(1,1,3,3-tetramethylbutyl)phenolato]](2-)-O,O',S]nickel	238-523-3	14516-71-3	-	View substance registered dossier
REACH24H CONSULTING GROUP	Paramount Court, Corrig Road, Sandyford Dublin 18 Dublin Ireland	Ireland	Active	(butylamine)[[2,2'-thiobis[4-(1,1,3,3-tetramethylbutyl)phenolato]](2-)-O,O',S]nickel	238-523-3	14516-71-3	2018; 2022	View substance registered dossier
REACH24H CONSULTING GROUP	Paramount Court, Corrig Road, Sandyford Dublin 18 Dublin Ireland	Ireland	Active	(butylamine)[[2,2'-thiobis[4-(1,1,3,3-tetramethylbutyl)phenolato]](2-)-O,O',S]nickel	238-523-3	14516-71-3	2018; 2020	View substance registered dossier
I.C.B. srl	via San Giuliano 4 30173 Venice Italy	Italy	Active	(butylamine)[[2,2'-thiobis[4-(1,1,3,3-tetramethylbutyl)phenolato]](2-)-O,O',S]nickel	238-523-3	14516-71-3	-	View substance registered dossier
REACH24H CONSULTING GROUP	Paramount Court, Corrig Road, Sandyford Dublin18 Dublin Ireland	Ireland	Active	(butylamine)[[2,2'-thiobis[4-(1,1,3,3-tetramethylbutyl)phenolato]](2-)-O,O',S]nickel	238-523-3	14516-71-3	-	View substance registered dossier
ICG Specialty Chemicals B.V	Maliestraat 3 3581 SH Utrecht Netherlands	Netherlands	Active	(butylamine)[[2,2'-thiobis[4-(1,1,3,3-tetramethylbutyl)phenolato]](2-)-O,O',S]nickel	238-523-3	14516-71-3	2020	View substance registered dossier
K CHIMICA	Via Taglio Sinistro 63A 30035 Mirano Veneto Italy	Italy	Active	(butylamine)[[2,2'-thiobis[4-(1,1,3,3-tetramethylbutyl)phenolato]](2-)-O,O',S]nickel	238-523-3	14516-71-3	2021	View substance registered dossier
Everkem Srl	Via Melchiorre Gioia, 168 20125 Milano Italy	Italy	Active	(butylamine)[[2,2'-thiobis[4-(1,1,3,3-tetramethylbutyl)phenolato]](2-)-O,O',S]nickel	238-523-3	14516-71-3	-	View substance registered dossier

Showing 901 - 1,000 of 26,866 results.

In this table, you will find all public data submitted to ECHA in REACH registration dossiers by substance manufacturers, importers, or their representatives, as laid out by the REACH Regulation (see Understanding REACH regulation).

ECHA makes available this information as REACH registered substance factsheets, which contain the full set of non-confidential information from related registration dossiers for a substance. Depending on the number of registrations that have been made for a substance, one factsheet can thus represent data from anything between hundreds of registration dossiers in a joint submission, to data from just one registration dossier.

As noted in the Legal Notice of the ECHA website, ECHA does not give any guarantees or warranties regarding the quality and correctness of the published information. The information in the portal is published ‘as provided’ by industry, and its accuracy has not been verified by ECHA. ECHA is also not in a position to intervene with, edit or correct the published data; this can only be done by the registrant responsible for its submission. Please also note that the information may be protected and its use may require prior permission from its owner (see the ECHA website Legal Notice more details).

In the portal results table are presented:

Public substance identity – the best available non-confidential substance name, EC, and CAS numbers.
Registration status – indicating the calculated registration status for the whole factsheet: Active – is being manufactured or imported to the EEA by one or more registrants; Cease Manufacture - is no longer being manufactured or imported above 1 tone per calendar year. All registrants of the substance have reported a cease of manufacture or import; or No longer valid - no longer considered registered under REACH and not currently allowed to be manufactured or imported to the EEA, until the substance is registered again.
Registration type – indicating whether a given factsheet contains data from a REACH full registration, REACH intermediate registration, or only a limited set of data inherited from a NONS notification.
Submission type – indicating whether the data in a given factsheet was submitted jointly or individually.
Total tonnage band – calculated per factsheet from all contributing registrations, based on the estimated quantity of the substance placed on the market. Data is excluded from dossiers where the tonnage is claimed confidential, from Intermediate registration dossiers, and from NONs which have not been updated.
Last updated – indicating the date on which this registered substance factsheet was last modified with new or updated data, based on an industry submission.
Link to the full factsheet.

Chemical Property Data Search

A subset of the key chemical properties (physico-chemical, environmental fate, ecotoxicological and toxicological data) of registered substances can be searched and accessed via the OECD eChemPortal.

RELATED INFORMATION

Welcome to the REACH Registered Substance Factsheets

Here you will find details from REACH registrations submitted to ECHA. Registrations under REACH can be submitted either jointly – where a group of legal entities pool their data – or individually. The set of details from each published joint or individual submission is presented as a row in the results table. For each row there is also an ‘eye’ icon leading to the detailed factsheet which contains the entire public dataset, following the IUCLID format.

Note that there can be more than one joint or individual submission for the same substance, thus there can be cases where one substance is covered by many REACH registered substance factsheets.

Note too, that as mentioned in the Legal Notice of the ECHA website, ECHA does not give any guarantees or warranties regarding the quality and correctness of the published information. The information in the portal is published ‘as provided’ by industry, and its accuracy has not been verified by ECHA. ECHA is also not in a position to intervene with, edit or correct the published data; this can only be done by the registrant responsible for its submission.

Finally, please note that the information may be protected and its use may require prior permission from its owner (see the ECHA website Legal Notice more details).

All substances table

The “All substances” table gives an overview of all the REACH registered substance factsheets on file at ECHA. Since this covers all data ever submitted since the entry into force of the REACH Regulation, there are some substances which are no longer considered registered under REACH in the EU / EEA. These can be for example substances that were registered only in the UK; since Brexit they are no longer registered in the EU / EEA.

The following columns are presented in the “All substances” table:

Public substance identity – the best available non-confidential substance name, EC, and CAS numbers.
Registration status – indicating the calculated registration status for the whole factsheet: Active – is being manufactured or imported to the EEA by one or more registrants; Cease Manufacture - is no longer being manufactured or imported above 1 tone per calendar year. All registrants of the substance have reported a cease of manufacture or import; or No longer valid - no longer considered registered under REACH and not currently allowed to be manufactured or imported to the EEA, until the substance is registered again.
Registration type – indicating whether a given factsheet contains data from a REACH full registration, REACH intermediate registration, or only a limited set of data inherited from a NONS notification.
Submission type – indicating whether the data in a given factsheet was submitted jointly or individually.
Total tonnage band – calculated per factsheet from all contributing registrations, based on the estimated quantity of the substance placed on the market. Data is excluded from dossiers where the tonnage is claimed confidential, from Intermediate registration dossiers, and from NONs which have not been updated.
Last updated – indicating the date on which this registered substance factsheet was last modified with new or updated data, based on an industry submission.
‘Eye’ icon linking to the full factsheet.

Searching

The search for REACH registered substance factsheets is divided into logically separated blocks of related search filters. Note that the search works so that if you provide filters in different blocks, then the results returned must match the filters in block 1 AND those in block 2 etc. Searches are conducted on all the public data included in all published REACH registrations.

Substance identity

In this block you can search by substance identifiers, under filters for Name, EC / List number, and CAS number. Full or partial identifiers can be used. And under the Name filter you can search by any substance name of any kind from any source. Other numerical identifiers such as Harmonised C&L Index number, or PIC CN code can also optionally be used.

Administrative data

In this block you can search by administrative information relating to REACH registered substance factsheets:

Registration type – picklist of Full, Intermediate, NONS
Registration status – picklist of Active, Cease Manufacture, No longer valid
Submission type – Individual or Joint
Country in which registered – picklist of current and former EU / EEA member states from which REACH registrations were received
First published date – the date when a REACH registration factsheet was first published
Last update date – the last date when any registrant / supplier submission contributing to a given REACH registration factsheet was submitted
Last update year – the year in which any registrant / supplier last made an update submission included in a given REACH registration factsheet
Registrant / supplier name – where available and not claimed confidential
Registration number – where available and not claimed confidential
Registrant address – where available and not claimed confidential

Substance data

In this block you can search by substance related data from REACH registered substance factsheets:

Tonnage band – picklist of Tonnage range, Tonnage Confidential, Intermediate use only
Selected total tonnage band range – available only if Tonnage range is selected, and allows to filter REACH registered substance factsheets within any selected min and max value
Substance has nanoform – picklist of Yes, No
PBT assessment outcome – picklist of all possible PBT assessment outcomes
CSA performed – picklist of Yes, No

Use and exposure

In this block you can search by elements relating to how use and exposure are encoded in REACH registrations.

Under the Life cycle option you can select one or more life cycle stages. The search results returned will include only factsheets containing uses reported under the selected life cycle stages.

Under the Category option there are modal popups for each of the use descriptor categories – Product, Sector of use, Process, Environmental release, and Article categories. In each of these are multi select picklists for all the related descriptor codes. The search results returned will include only factsheets containing uses which include the selected descriptor codes.

Note that the Life cycle and Category options work together, so that if a life cycle stage and Category options are both selected the search results will include factsheets containing specific uses in the selected life cycle stage, and where the use includes the selected descriptor codes.

With the search operator option you can select to refine how the search works. AND refines results and returns only those factsheets where ALL the search filter criteria are met. OR broadens the results and returns factsheets where ANY of the selected search filter criteria are met.

The factsheets

There is always a detailed factsheet per joint or individual submission, and it is generated based primarily on the IUCLID format.

The factsheet header begins with the identity of the substance in question, to which the factsheet is linked. The substance identity should always be aligned with that shown in the related substance Infocard. Note that since the Infocard refreshes daily, whereas the factsheet sometimes refreshes on a slower pace, sometimes the data may be out of alignment. In such cases it will always realign as quickly as possible.

The substance identification is enriched with the data provided in the relevant IUCLID section of the primary submitted dossier – either the joint submission lead, or the single individual submission.

In this section are also provided the type of substance, all other identifiers such as trade names, common names, other names etc, as well as all distinct submitted compositions for the substance.

Next is a page covering administrative type information from the data submitted, including:

Registration details, on the total tonnage band informed to ECHA, the registration type, first published and last updated dates, and whether a chemical safety assessment has been performed.

Registrant / supplier details, giving the identity and status of registrants / suppliers, except where the identity has been claimed confidential.

Registration numbers, giving again the identity and status of registration numbers, except where claimed confidential.

Contact persons responsible for the SDS, giving the non-confidential SDS contacts provided to ECHA.

The remainder of the factsheet faithfully follows the IUCLID structure, covering the C&L and PBT, Manufacture, use, and exposure, Physical and chemical properties, Environmental fate and pathways, Ecotoxicological information, Toxicological information, Analytical methods (if available), Guidance on safe use, Assessment reports, and Reference substances.