Registered substances

Data platform availability banner - registered substances

New Data Availability System

A new Data Availability System is being developed by ECHA. To begin with this system will take over the responsibility of making REACH registration data available, once it is ready. We expect the first version to be publicly available by the end of 2023.

Since ECHA aims to devote our maximum effort to this new system, we can no longer maintain REACH registration data on the current Dissemination Platform. As such once the IUCLID format change begins on 19th May 2023 we will no longer update REACH registered substance factsheets. The factsheets will remain online, but will not be updated.

New and updated REACH registration submissions, as well as all registrations on file, will be made available in the new system when it is ready. We will inform you of what you can expect in the new system, along with details of when and where to find it.

We appreciate your understanding in the meantime.

DISSEMINATION
PLATFORM

REACH - Registration, Evaluation, Authorisation and Restriction of Chemicals Regulation

Registered Substances Factsheets

Substances which have been registered and can be placed on the EEA market by those companies with a valid registration



No results were found
Details
4-Fluoro-3-hydroxybenzoic acid
434-190-5 - No longer Valid NONS Individual No longer valid 10-11-2008 View substance registered dossier
4-Fluoro-3-hydroxybenzoic acid
434-190-5 - Active Intermediate Joint Intermediate use only 28-08-2019 View substance registered dossier
4-fluoro-N-(propan-2-yl)aniline
448-100-7 - Active Intermediate Joint Intermediate use only 13-05-2022 View substance registered dossier
4-hexadecyl-1-phenylpyrazolidin-3-one
430-840-7 - Active NONS Joint Tonnage data confidential 10-03-2011 View substance registered dossier
4-Hydroxy-3,5-dimethylbenzonitrile
452-810-2 - Active Full Joint ≥ 1 to < 10 tonnes 23-05-2018 View substance registered dossier
4-Hydroxy-3,5-dimethylbenzonitrile
452-810-2 - Cease Manufacture NONS Individual Cease manufacture 14-09-2010 View substance registered dossier
4-hydroxy-3-methyl-5-[(1R)-2,2,3-trimethylcyclopent-3-en-1-yl]pentan-2-one
949-712-1 - Active Intermediate Joint Intermediate use only 11-02-2019 View substance registered dossier
4-hydroxybutan-2-one + 3-(hydroxymethyl)but-3-en-2-one
908-868-0 - Active Intermediate Joint Intermediate use only 22-01-2020 View substance registered dossier
4-hydroxybutane-1-sulfonic acid
928-903-3 - Active Intermediate Individual Intermediate use only 29-04-2015 View substance registered dossier
4-hydroxyphenyl 4-(allyloxy)benzoate
4-ALLYLOXYBENZOESÄUREHYDROCHINONESTER
433-210-1 - Active NONS Joint Tonnage data confidential 10-11-2008 View substance registered dossier
4-hydroxystyrene, 4-tbutoxy styrene and styrene copolymer
433-660-7 - Active NONS Joint Tonnage data confidential 10-11-2008 View substance registered dossier
4-Isobutylbenzaldehyde
464-400-0 - Active NONS Joint Tonnage data confidential 22-07-2014 View substance registered dossier
4-Methoxy-5-(3-morpholin-4-yl-propoxy)-2-nitro-benzonitrile
936-067-6 - Cease Manufacture Intermediate Joint Cease manufacture 24-10-2017 View substance registered dossier
4-methoxybenzyl 3-chloromethyl-5-oxo-6-phenylacetamido-(2H)5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate
GCLE
403-040-0 - Active NONS Joint Tonnage data confidential 10-11-2008 View substance registered dossier
4-methoxybenzyl 3-chloromethyl-5-oxo-6-phenylacetamido-(2H)5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate
GCLE
403-040-0 - Active Intermediate Individual Intermediate use only 16-11-2011 View substance registered dossier
4-Methoxycarbonyl-2-methylthiophen-3-yl-ammonium hydrochloride
929-732-7 - Active Intermediate Joint Intermediate use only 21-02-2013 View substance registered dossier
4-methoxycyclohexanone
480-410-8 - Active Intermediate Joint Intermediate use only 11-11-2022 View substance registered dossier
4-Methyl-2-propylbenzimidazole-6-carboxylic acid
424-450-6 - Active Intermediate Individual Intermediate use only 21-04-2010 View substance registered dossier
4-Methyl-2-propylbenzimidazole-6-carboxylic acid
424-450-6 - Active NONS Joint Tonnage data confidential 10-11-2008 View substance registered dossier
4-methyl-5-(2-(1,1,1-trifluoro-2-methylpropan-2-yl)pyridin-4-yl)thiazol-2-amine dihydrobromide
946-432-1 - Active Intermediate Individual Intermediate use only 09-01-2018 View substance registered dossier
No results were found
Registrant/Supplier Address Country Registration Status Name EC / List no. CAS no. Last update year Details
- - - - 4-Fluoro-3-hydroxybenzoic acid 434-190-5 - - View substance registered dossier
Fareva La Vallée 928 avenue Lavoisier ZI de Blavozy 43700 Saint Germain Laprade Auvergne France France Active 4-Fluoro-3-hydroxybenzoic acid 434-190-5 - - View substance registered dossier
Saltigo GmbH HSEQ-RA Kaiser-Wilhelm-Allee 40 51373 Leverkusen Germany Germany Active 4-fluoro-N-(propan-2-yl)aniline 448-100-7 - 2010; 2022 View substance registered dossier
Bayer AG Kaiser-Wilhelm-Allee 1 51373 Leverkusen Germany Germany Active 4-fluoro-N-(propan-2-yl)aniline 448-100-7 - 2010; 2014; 2020; 2021 View substance registered dossier
ACETO GmbH Hans-Henny-Jahnn-Weg 53 22085 Hamburg Germany Germany Active 4-fluoro-N-(propan-2-yl)aniline 448-100-7 - - View substance registered dossier
[Confidential] - - - 4-fluoro-N-(propan-2-yl)aniline 448-100-7 - - View substance registered dossier
FujiFilm Manufacturing Europe BV Oudenstaart 1 5047 TK Tilburg Netherlands Netherlands Active 4-hexadecyl-1-phenylpyrazolidin-3-one 430-840-7 - 2011 View substance registered dossier
Honeywell Specialty Chemicals Seelze GmbH Wunstorfer Str. 40 30926 Seelze Deutschland Germany Germany Cease Manufacture 4-hexadecyl-1-phenylpyrazolidin-3-one 430-840-7 - 2020 View substance registered dossier
Janssen Pharmaceutical Science Unlimited Company Little Island County NA Cork Ireland Ireland Active 4-Hydroxy-3,5-dimethylbenzonitrile 452-810-2 - 2018 View substance registered dossier
Janssen Pharmaceutica N.V. Turnhoutseweg 30 2340 Beerse Belgium Belgium Cease Manufacture 4-Hydroxy-3,5-dimethylbenzonitrile 452-810-2 - 2019 View substance registered dossier
TAKASAGO TICSA-Producer/Importer Avenida de Mazarrón, 49 30120 El Palmar Murcia Spain Spain Active 4-hydroxy-3-methyl-5-[(1R)-2,2,3-trimethylcyclopent-3-en-1-yl]pentan-2-one 949-712-1 - - View substance registered dossier
DSM Nutritional Products GmbH - OR1 Emil-Barell-Str. 3 79639 Grenzach-Wyhlen Germany Germany Active 4-hydroxybutan-2-one + 3-(hydroxymethyl)but-3-en-2-one 908-868-0 - 2020 View substance registered dossier
ORGANICA Feinchemie GmbH Wolfen Ortsteil Wolfen Kunstseidestraße 5 06766 Bitterfeld-Wolfen Germany Germany Active 4-hydroxybutane-1-sulfonic acid 928-903-3 - - View substance registered dossier
- - - - 4-hydroxyphenyl 4-(allyloxy)benzoate 433-210-1 - - View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant German competent national authority. - - No longer Valid 4-hydroxyphenyl 4-(allyloxy)benzoate 433-210-1 - 2022 View substance registered dossier
- - - - 4-hydroxystyrene, 4-tbutoxy styrene and styrene copolymer 433-660-7 - - View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant Dutch competent national authority. - - Active 4-hydroxystyrene, 4-tbutoxy styrene and styrene copolymer 433-660-7 - - View substance registered dossier
MITSUBISHI GAS CHEMICAL EUROPE GMBH Immermannstr.13 40210 Duesseldorf Germany Germany Active 4-Isobutylbenzaldehyde 464-400-0 - 2014 View substance registered dossier
MITSUBISHI GAS CHEMICAL EUROPE GMBH Immermannstr. 13 40210 Duesseldorf Germany Germany Active 4-Isobutylbenzaldehyde 464-400-0 - 2014 View substance registered dossier
Patheon Austria GmbH & Co KG St. Peterstrasse 25 A-4020 Linz Austria Austria Cease Manufacture 4-Methoxy-5-(3-morpholin-4-yl-propoxy)-2-nitro-benzonitrile 936-067-6 - 2022 View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant Spanish competent national authority. - - No longer Valid 4-methoxybenzyl 3-chloromethyl-5-oxo-6-phenylacetamido-(2H)5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate 403-040-0 - 2022 View substance registered dossier
Bristol Myers Squibb Srl Via del Murillo., km 2, 8 004013 Sermoneta Lazio Italy Italy Active 4-methoxybenzyl 3-chloromethyl-5-oxo-6-phenylacetamido-(2H)5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate 403-040-0 - - View substance registered dossier
ACS DOBFAR S.p.A Viale Addetta 4/12 20067 Tribiano Milano Italy Italy Active 4-methoxybenzyl 3-chloromethyl-5-oxo-6-phenylacetamido-(2H)5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate 403-040-0 - - View substance registered dossier
CBW Chemie GmbH Bitterfeld-Wolfen Kühlturmstrasse 3 06803 Bitterfeld-Wolfen / OT Greppin Germany Germany Active 4-Methoxycarbonyl-2-methylthiophen-3-yl-ammonium hydrochloride 929-732-7 - 2013 View substance registered dossier
AllessaProduktion GmbH Alt-Fechenheim 34 60386 Frankfurt am Main Germany Germany Cease Manufacture 4-methoxycyclohexanone 480-410-8 - 2019 View substance registered dossier
Saltigo GmbH HSEQ-RA Kaiser-Wilhelm-Allee 40 51373 Leverkusen Germany Germany Active 4-methoxycyclohexanone 480-410-8 - 2008; 2011; 2017 View substance registered dossier
BASF SE Carl-Bosch-Str. 38 67056 Ludwigshafen am Rhein Rheinland-Pfalz Germany Germany Active 4-methoxycyclohexanone 480-410-8 - - View substance registered dossier
Bayer AG Kaiser-Wilhelm-Allee 1 51373 Leverkusen Germany Germany Active 4-methoxycyclohexanone 480-410-8 - 2011; 2022 View substance registered dossier
AGC Pharma Chemicals Europe, S.L.U. Camí de la Pomereda, 13 08380 Malgrat de Mar (Barcelona) Spain Spain Active 4-Methyl-2-propylbenzimidazole-6-carboxylic acid 424-450-6 - - View substance registered dossier
Boehringer Ingelheim Pharma GmbH & Co. KG Binger Strasse 173 55216 Ingelheim am Rhein Germany Germany Cease Manufacture 4-Methyl-2-propylbenzimidazole-6-carboxylic acid 424-450-6 - 2015 View substance registered dossier
ORGAPHARM Rue du Moulin de la Canne 45300 PITHIVIERS France France Active 4-Methyl-2-propylbenzimidazole-6-carboxylic acid 424-450-6 - - View substance registered dossier
Merck KGaA Frankfurter Strasse 250 64293 Darmstadt Germany Germany Cease Manufacture 4-Methyl-2-propylbenzimidazole-6-carboxylic acid 424-450-6 - 2019 View substance registered dossier
Lek Pharmaceuticals d.d. Verovskova 57 1526 Ljubljana Slovenia Slovenia Active 4-methyl-5-(2-(1,1,1-trifluoro-2-methylpropan-2-yl)pyridin-4-yl)thiazol-2-amine dihydrobromide 946-432-1 - - View substance registered dossier

In this table, you will find all public data submitted to ECHA in REACH registration dossiers by substance manufacturers, importers, or their representatives, as laid out by the REACH Regulation (see Understanding REACH regulation).

ECHA makes available this information as REACH registered substance factsheets, which contain the full set of non-confidential information from related registration dossiers for a substance. Depending on the number of registrations that have been made for a substance, one factsheet can thus represent data from anything between hundreds of registration dossiers in a joint submission, to data from just one registration dossier.

As noted in the Legal Notice of the ECHA website, ECHA does not give any guarantees or warranties regarding the quality and correctness of the published information. The information in the portal is published ‘as provided’ by industry, and its accuracy has not been verified by ECHA. ECHA is also not in a position to intervene with, edit or correct the published data; this can only be done by the registrant responsible for its submission. Please also note that the information may be protected and its use may require prior permission from its owner (see the ECHA website Legal Notice more details).

In the portal results table are presented:

  • Public substance identity – the best available non-confidential substance name, EC, and CAS numbers.
  • Registration status – indicating the calculated registration status for the whole factsheet: Active – is being manufactured or imported to the EEA by one or more registrants; Cease Manufacture - is no longer being manufactured or imported above 1 tone per calendar year. All registrants of the substance have reported a cease of manufacture or import; or No longer valid - no longer considered registered under REACH and not currently allowed to be manufactured or imported to the EEA, until the substance is registered again.
  • Registration type – indicating whether a given factsheet contains data from a REACH full registration, REACH intermediate registration, or only a limited set of data inherited from a NONS notification.
  • Submission type – indicating whether the data in a given factsheet was submitted jointly or individually.
  • Total tonnage band – calculated per factsheet from all contributing registrations, based on the estimated quantity of the substance placed on the market. Data is excluded from dossiers where the tonnage is claimed confidential, from Intermediate registration dossiers, and from NONs which have not been updated.
  • Last updated – indicating the date on which this registered substance factsheet was last modified with new or updated data, based on an industry submission.
  • Link to the full factsheet.

A subset of the key chemical properties (physico-chemical, environmental fate, ecotoxicological and toxicological data) of registered substances can be searched and accessed via the OECD eChemPortal.