Registered substances

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New Data Availability System

A new Data Availability System is being developed by ECHA. To begin with this system will take over the responsibility of making REACH registration data available, once it is ready. We expect the first version to be publicly available by the end of 2023.

Since ECHA aims to devote our maximum effort to this new system, we can no longer maintain REACH registration data on the current Dissemination Platform. As such once the IUCLID format change begins on 19th May 2023 we will no longer update REACH registered substance factsheets. The factsheets will remain online, but will not be updated.

New and updated REACH registration submissions, as well as all registrations on file, will be made available in the new system when it is ready. We will inform you of what you can expect in the new system, along with details of when and where to find it.

We appreciate your understanding in the meantime.

DISSEMINATION
PLATFORM

REACH - Registration, Evaluation, Authorisation and Restriction of Chemicals Regulation

Registered Substances Factsheets

Substances which have been registered and can be placed on the EEA market by those companies with a valid registration



No results were found
Details
tert-Butyl 4-({6-[7-cyclopentyl-6-(dimethylcarbamoyl)-7H-pyrrolo[2,3-d]pyrimidin-2-yl]amino}pyridin-3-yl)piperazine-1-carboxylate
810-753-4 1374639-78-7 No longer Valid Full Individual No longer valid 27-08-2019 View substance registered dossier
tert-butyl 4-(methylsulfonyloxymethyl)piperidine-1-carboxylate
800-659-1 161975-39-9 Active Intermediate Joint Intermediate use only 12-05-2022 View substance registered dossier
tert-butyl 4-(aminomethyl)piperidine-1-carboxylate;2-hydroxypropane-1,2,3-tricarboxylic acid
870-310-6 2368870-32-8 Active Intermediate Joint Intermediate use only 28-07-2021 View substance registered dossier
tert-Butyl 4-(6-nitropyridin-3-yl)piperazine-1-carboxylate
801-163-8 571189-16-7 Active Intermediate Joint Intermediate use only 17-12-2021 View substance registered dossier
tert-butyl 4-(6-aminopyridin-3-yl)piperazine-1-carboxylate
695-268-4 571188-59-5 Active Full Individual ≥ 10 to < 100 tonnes 24-07-2018 View substance registered dossier
tert-butyl 4-(6-aminopyridin-3-yl)piperazine-1-carboxylate
695-268-4 571188-59-5 Active Intermediate Joint Intermediate use only 22-09-2021 View substance registered dossier
tert-butyl 4-(6-aminopyridin-3-yl)piperazine-1-carboxylate
695-268-4 571188-59-5 Active Intermediate Individual Intermediate use only 16-07-2013 View substance registered dossier
tert-butyl 4-((4'-chloro-5,5-dimethyl-3,4,5,6-tetrahydro-[1,1'-biphenyl]-2-yl)methyl)piperazine-1-carboxylate
941-919-5 1228780-71-9 Active Intermediate Joint Intermediate use only 27-11-2015 View substance registered dossier
tert-butyl 3-oxobutanoate
216-904-5 1694-31-1 Active Full Joint ≥ 10 to < 100 tonnes 07-05-2018 View substance registered dossier
tert-butyl 3-oxobutanoate
216-904-5 1694-31-1 Active Intermediate Joint Intermediate use only 08-02-2022 View substance registered dossier
Tert-butyl 3-Cyano-4-oxo-pyrrolidine-1-carboxylate
700-004-9 175463-32-8 Active Intermediate Individual Intermediate use only 12-02-2009 View substance registered dossier
tert-butyl 3-[(2S)-3-[[(1S)-1-[[(1S,2S)-1-[[(1S)-2-[[2-[[2-[(2S)-2-[[(1S)-2-[[(1S)-2-[[2-[[(1S)-2-[(2S)-2-[(2S)-2-[(2S)-2-[[(1S)-2-amino-1-(tert-butoxymethyl)-2-oxo-ethyl]carbamoyl]pyrrolidine-1-carbonyl]pyrrolidine-1-carbonyl]pyrrolidin-1-yl]-1-methyl-2-oxo-ethyl]amino]-2-oxo-ethyl]amino]-1-(tert-butoxymethyl)-2-oxo-ethyl]amino]-1-(tert-butoxymethyl)-2-oxo-ethyl]carbamoyl]pyrrolidin-1-yl]-2-oxo-ethyl]amino]-2-oxo-ethyl]amino]-1-methyl-2-oxo-ethyl]carbamoyl]-2-methyl-butyl]carbamoyl]-3-methyl-butyl]amino]-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S,3S)-2-[[(2S)-2-[[(2S)-4-tert-butoxy-2-[[(2S)-2-[[2-[[(2S,3S)-2-[[(2S)-3-tert-butoxy-2-[[(2S)-2-[[(2S)-4-tert-butoxy-2-[[(2S)-3-tert-butoxy-2-[[(2S,3R)-3-tert-butoxy-2-[[(2S)-2-[[(2S,3R)-3-tert-butoxy-2-[[2-[[(2S)-5-tert-butoxy-2-[[2-[[(2S)-2-(tert-butoxycarbonylamino)-3-(4-tert-butoxyphenyl)propanoyl]amino]-2-methyl-propanoyl]amino]-5-oxo-pentanoyl]amino]acetyl]amino]butanoyl]amino]-3-phenyl-propanoyl]amino]butanoyl]amino]propanoyl]amino]-4-oxo-butanoyl]amino]-3-(4-tert-butoxyphenyl)propanoyl]amino]propanoyl]amino]-3-methyl-pentanoyl]amino]-2-methyl-propanoyl]amino]-4-methyl-pentanoyl]amino]-4-oxo-butanoyl]amino]-6-(tert-butoxycarbonylamino)hexanoyl]amino]-3-methyl-pentanoyl]amino]propanoyl]amino]-5-oxo-5-(tritylamino)pentanoyl]amino]-6-[[2-[2-[2-[[2-[2-[2-[[(4S)-5-tert-butoxy-4-[(20-tert-butoxy-20-oxo-icosanoyl)amino]-5-oxo-pentanoyl]amino]ethoxy]ethoxy]acetyl]amino]ethoxy]ethoxy]acetyl]amino]hexanoyl]amino]propanoyl]amino]-3-phenyl-propanoyl]amino]-3-methyl-butanoyl]amino]-5-oxo-5-(tritylamino)pentanoyl]amino]-3-oxo-propyl]indole-1-carboxylate
955-944-4 - Active Intermediate Individual Intermediate use only 25-07-2022 View substance registered dossier
tert-butyl 3-[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-3-phenyl-propanoyl]amino]-3-methyl-butanoyl]amino]-5-oxo-5-(tritylamino)pentanoyl]amino]-3-[[(1S)-1-[[(1S,2S)-1-[[(1S)-2-(2-hydroxyethylamino)-1-methyl-2-oxo-ethyl]carbamoyl]-2-methyl-butyl]carbamoyl]-3-methyl-butyl]amino]-3-oxo-propyl]indole-1-carboxylate
874-918-2 2461524-68-3 Active Intermediate Individual Intermediate use only 10-10-2022 View substance registered dossier
tert-butyl 3,5,5-trimethylperoxyhexanoate
236-050-7 13122-18-4 Active Full Joint ≥ 1 000 to < 10 000 tonnes 11-04-2023 View substance registered dossier
tert-butyl 2-oxopyrrolidine-1-carboxylate
617-776-7 85909-08-6 Active Intermediate Joint Intermediate use only 05-03-2020 View substance registered dossier
tert-butyl 2-hydroxyisobutyrate
252-952-3 36293-63-7 Active Intermediate Joint Intermediate use only 08-11-2017 View substance registered dossier
tert-butyl 2-ethylperoxyhexanoate
221-110-7 3006-82-4 Active Full Joint ≥ 1 000 to < 10 000 tonnes 22-04-2022 View substance registered dossier
tert-butyl 2-bromopropanoate
675-664-3 39149-80-9 Active Intermediate Joint Intermediate use only 24-04-2018 View substance registered dossier
Tert-butyl 2-[4-(2-pyridinyl) phenylmethyl] hydrazine carboxylate
429-080-9 - Active Full Joint ≥ 1 to < 10 tonnes 12-10-2017 View substance registered dossier
Tert-butyl 2-[4-(2-pyridinyl) phenylmethyl] hydrazine carboxylate
429-080-9 - Active NONS Joint Tonnage data confidential 10-11-2008 View substance registered dossier
tert-butyl 2-[(4R,6S)-6-(hydroxymethyl)-2,2-dimethyl-1,3-dioxan-4-yl]acetate
432-960-5 124655-09-0 Active Intermediate Joint Intermediate use only 20-05-2014 View substance registered dossier
tert-butyl 2-[(4R,6R)-6-{2-[2-(4-fluorophenyl)-3-phenyl-4-(phenylcarbamoyl)-5-(propan-2-yl)-1H-pyrrol-1-yl]ethyl}-2,2-dimethyl-1,3-dioxan-4-yl]acetate
700-258-0 125971-95-1 Active Intermediate Individual Intermediate use only 29-09-2010 View substance registered dossier
tert-butyl 2-[(4R,6R)-6-{2-[2-(4-fluorophenyl)-3-phenyl-4-(phenylcarbamoyl)-5-(propan-2-yl)-1H-pyrrol-1-yl]ethyl}-2,2-dimethyl-1,3-dioxan-4-yl]acetate
700-258-0 125971-95-1 Active Intermediate Individual Intermediate use only 27-10-2010 View substance registered dossier
tert-butyl 2-[(4R,6R)-6-{2-[2-(4-fluorophenyl)-3-phenyl-4-(phenylcarbamoyl)-5-(propan-2-yl)-1H-pyrrol-1-yl]ethyl}-2,2-dimethyl-1,3-dioxan-4-yl]acetate
700-258-0 125971-95-1 Active Intermediate Joint Intermediate use only 09-06-2022 View substance registered dossier
tert-butyl 2-[(4R,6R)-6-{2-[2-(4-fluorophenyl)-3-phenyl-4-(phenylcarbamoyl)-5-(propan-2-yl)-1H-pyrrol-1-yl]ethyl}-2,2-dimethyl-1,3-dioxan-4-yl]acetate
700-258-0 125971-95-1 Active Intermediate Individual Intermediate use only 04-03-2011 View substance registered dossier
tert-butyl 2-[(2S,3S)-2-(benzyloxy)pentan-3-yl]hydrazinecarboxylate
606-022-2 184177-88-6 Active Intermediate Individual Intermediate use only 30-05-2018 View substance registered dossier
tert-butyl 2-((4R,6S)-6-((E)-2-(4-(4-fluorophenyl)-6-isopropyl-2-(N-methylmethylsulfonamido)pyrimidin-5-yl)vinyl)-2,2-dimethyl-1,3-dioxan-4-yl)acetate
432-810-9 - Active Intermediate Joint Intermediate use only 02-12-2020 View substance registered dossier
tert-butyl 2-((4R,6S)-6-((E)-2-(4-(4-fluorophenyl)-6-isopropyl-2-(N-methylmethylsulfonamido)pyrimidin-5-yl)vinyl)-2,2-dimethyl-1,3-dioxan-4-yl)acetate
432-810-9 - Active Intermediate Joint Intermediate use only 24-10-2012 View substance registered dossier
tert-butyl 2-((1H-pyrrolo[2,3-b]pyridin-5-yl)oxy)-4-bromobenzoate
942-459-8 1628047-84-6 Active Intermediate Joint Intermediate use only 23-11-2015 View substance registered dossier
tert-butyl 1H-pyrrol-1-ylcarbamate
810-523-3 937046-95-2 Active Intermediate Individual Intermediate use only 27-02-2018 View substance registered dossier
tert-butyl 1H-pyrrol-1-ylcarbamate
810-523-3 937046-95-2 Cease Manufacture Intermediate Individual Cease manufacture 24-08-2015 View substance registered dossier
tert-butyl (triphenylphosphoranylidene) acetate
1,1-DIMETHYLETHOXY-CARBONYL-METHYLEN-TRIPHENYLPHOSPHORAN; DMY; PHOSPHORANE
412-880-7 35000-38-5 Active NONS Joint Tonnage data confidential 14-07-2011 View substance registered dossier
tert-butyl (S)-2-carbamoylpyrrolidine-1-carboxylate
626-262-1 35150-07-3 Active Intermediate Joint Intermediate use only 28-11-2017 View substance registered dossier
tert-butyl (5S,6R,7R)-3-bromomethyl-5,8-dioxo-7-(2-phenylacetamido)-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate
3-BMC
407-620-4 33610-13-8 Active NONS Individual Tonnage data confidential 10-11-2008 View substance registered dossier
tert-butyl (4R)-cis-6-cyanomethyl-2,2-dimethyl-1,3-dioxane-4-acetate
PD138153
425-780-3 125971-94-0 Active Intermediate Joint Intermediate use only 16-03-2018 View substance registered dossier
tert-butyl (4R)-cis-6-cyanomethyl-2,2-dimethyl-1,3-dioxane-4-acetate
PD138153
425-780-3 125971-94-0 Active NONS Joint Tonnage data confidential 10-11-2008 View substance registered dossier
tert-butyl (4-bromo-2-cyano-1H-pyrrol-1-yl)carbamate
810-525-4 937047-04-6 Active Intermediate Individual Intermediate use only 23-04-2019 View substance registered dossier
tert-butyl (4-bromo-2-cyano-1H-pyrrol-1-yl)carbamate
810-525-4 937047-04-6 Cease Manufacture Intermediate Individual Cease manufacture 24-08-2015 View substance registered dossier
tert-butyl (3S,6S)-3-((tert-butyldimethylsilyl)oxy)-6-chloro-6-((3aS,4S,6S,7aR)-3a,5,5-trimethylhexahydro-4,6-methanobenzo[d][1,3,2]dioxaborol-2-yl)hexanoate
811-363-7 1681053-96-2 Active Intermediate Joint Intermediate use only 02-05-2018 View substance registered dossier
tert-butyl (3S,5S)-3-isopropyl-5-((2S,4S)-tetrahydro-4-isopropyl-5-oxo-furan-2-yl)-2-oxo-pyrrolidine-carboxylate
472-680-0 - No longer Valid NONS Individual No longer valid 15-12-2008 View substance registered dossier
tert-butyl (3S)-3-hydroxypiperidine-1-carboxylate
626-373-5 143900-44-1 Active Intermediate Individual Intermediate use only 06-10-2021 View substance registered dossier
tert-butyl (3R,5S,6E)-7-[4-(4-fluorophenyl)-2-(N-methylmethanesulfonamido)-6-(propan-2-yl)pyrimidin-5-yl]-3,5-dihydroxyhept-6-enoate
609-144-4 355806-00-7 Active Intermediate Joint Intermediate use only 13-03-2020 View substance registered dossier
tert-butyl (3R)-3-{3-iodo-4-[(triphenylphosphanylidene)amino]-1H-pyrazolo[3,4-d]pyrimidin-1-yl}piperidine-1-carboxylate
953-572-7 - Active Intermediate Individual Intermediate use only 06-07-2022 View substance registered dossier
tert-butyl (2S,4S)-2-[4-(2-{(2S,5S)-1-[N-(methoxycarbonyl)-L-valyl]-5-methylpyrrolidin-2-yl}-1,11-dihydroisochromeno[4',3':6,7]naphtho[1,2-d]imidazol-9-yl)-1H-imidazol-2-yl]-4-(methoxymethyl)pyrrolidine-1-carboxylate
807-100-0 1378391-45-7 Active Intermediate Individual Intermediate use only 28-09-2016 View substance registered dossier
tert-butyl (2S)-2-{5-[4-(4-{2-[(2S)-1-[(tert-butoxy)carbonyl]pyrrolidin-2-yl]-1H-imidazol-5-yl}phenyl)phenyl]-1H-imidazol-2-yl}pyrrolidine-1-carboxylate
941-432-8 - Active Intermediate Individual Intermediate use only 26-09-2014 View substance registered dossier
tert-butyl (2S)-2-carbamoyl-2,3-dihydropyrrole-1-carboxylate
615-204-0 709031-38-9 Active Intermediate Individual Intermediate use only 21-03-2017 View substance registered dossier
tert-butyl (2S)-2-(3-fluoro-4-phenylphenyl)propanoate
945-962-0 - Active Intermediate Joint Intermediate use only 07-12-2017 View substance registered dossier
tert-butyl (2-cyano-1H-pyrrol-1-yl)carbamate
810-524-9 937046-96-3 Cease Manufacture Intermediate Individual Cease manufacture 24-08-2015 View substance registered dossier
tert-butyl (2-cyano-1H-pyrrol-1-yl)carbamate
810-524-9 937046-96-3 Active Intermediate Individual Intermediate use only 26-03-2019 View substance registered dossier
tert-butyl (1S,3S,5S)-3-carbamoyl-2-azabicyclo[3.1.0]hexane-2-carboxylate
609-213-9 361440-67-7 Active Intermediate Individual Intermediate use only 20-03-2017 View substance registered dossier
No results were found
Registrant/Supplier Address Country Registration Status Name EC / List no. CAS no. Last update year Details
Novartis Grimsby Limited Moody Lane, Pyewipe DN31 2SR Grimsby N.E. Lincolnshire United Kingdom United Kingdom No longer Valid tert-Butyl 4-({6-[7-cyclopentyl-6-(dimethylcarbamoyl)-7H-pyrrolo[2,3-d]pyrimidin-2-yl]amino}pyridin-3-yl)piperazine-1-carboxylate 810-753-4 1374639-78-7 2021 View substance registered dossier
Merck KGaA Frankfurter Strasse 250 64293 Darmstadt Germany Germany Active tert-butyl 4-(methylsulfonyloxymethyl)piperidine-1-carboxylate 800-659-1 161975-39-9 - View substance registered dossier
Merck KGaA Frankfurter Strasse 250 64293 Darmstadt Germany Germany Active tert-butyl 4-(aminomethyl)piperidine-1-carboxylate;2-hydroxypropane-1,2,3-tricarboxylic acid 870-310-6 2368870-32-8 - View substance registered dossier
MinAscent Leuna Production GmbH Am Haupttor Gebäude 4208 06237 Leuna Germany Germany Active tert-Butyl 4-(6-nitropyridin-3-yl)piperazine-1-carboxylate 801-163-8 571189-16-7 2021 View substance registered dossier
PCAS 21 Chemin de la Sauvegarde 21 Ecully Parc - CS33167 69134 ECULLY France France Active tert-Butyl 4-(6-nitropyridin-3-yl)piperazine-1-carboxylate 801-163-8 571189-16-7 2015; 2017; 2021 View substance registered dossier
Pfizer Ireland Pharmaceuticals n/a P43 X336 Ringaskiddy Cork Ireland Ireland Active tert-Butyl 4-(6-nitropyridin-3-yl)piperazine-1-carboxylate 801-163-8 571189-16-7 - View substance registered dossier
PCAS 21 Chemin de la Sauvegarde 21 Ecully Parc - CS33167 69134 ECULLY France France No longer Valid tert-Butyl 4-(6-nitropyridin-3-yl)piperazine-1-carboxylate 801-163-8 571189-16-7 - View substance registered dossier
Novartis Integrated Services Limited Ringaskiddy P43 FR63 Ringaskiddy Co. Cork Ireland Ireland Active tert-butyl 4-(6-aminopyridin-3-yl)piperazine-1-carboxylate 695-268-4 571188-59-5 - View substance registered dossier
Pfizer Ireland Pharmaceuticals n/a P43 X336 Ringaskiddy Cork Ireland Ireland Active tert-butyl 4-(6-aminopyridin-3-yl)piperazine-1-carboxylate 695-268-4 571188-59-5 - View substance registered dossier
PCAS 21 Chemin de la Sauvegarde 21 Ecully Parc - CS33167 69134 ECULLY France France Active tert-butyl 4-(6-aminopyridin-3-yl)piperazine-1-carboxylate 695-268-4 571188-59-5 2021 View substance registered dossier
MinAscent Leuna Production GmbH Am Haupttor Gebäude 4208 06237 Leuna Germany Germany Active tert-butyl 4-(6-aminopyridin-3-yl)piperazine-1-carboxylate 695-268-4 571188-59-5 - View substance registered dossier
[Confidential] - - - tert-butyl 4-((4'-chloro-5,5-dimethyl-3,4,5,6-tetrahydro-[1,1'-biphenyl]-2-yl)methyl)piperazine-1-carboxylate 941-919-5 1228780-71-9 - View substance registered dossier
Valtris Specialty Chemicals Ltd Lankro Way PO Box 1 , Eccles M30 OLX Manchester Greater Manchester United Kingdom United Kingdom No longer Valid tert-butyl 3-oxobutanoate 216-904-5 1694-31-1 2021 View substance registered dossier
Global Product Compliance (Europe) AB IDEON, Beta 5, Scheelevägen 17 223 63 Lund Sweden Sweden Active tert-butyl 3-oxobutanoate 216-904-5 1694-31-1 2018 View substance registered dossier
Eastman Chemical B.V. Watermanweg 70 3067 GG Rotterdam Netherlands Netherlands Active tert-butyl 3-oxobutanoate 216-904-5 1694-31-1 - View substance registered dossier
SYNTHESIA TECHNOLOGY EUROPE S.L.U C/ Argent, 3 08755 Castellbisbal (Barcelona) Spain Spain Active tert-butyl 3-oxobutanoate 216-904-5 1694-31-1 - View substance registered dossier
YOU Solutions Germany GmbH - REACH (part of Arxada) Freundallee 9 a 30173 Hannover Germany Germany Active tert-butyl 3-oxobutanoate 216-904-5 1694-31-1 2017 View substance registered dossier
F.I.S. Fabbrica Italiana Sintetici S.p.a. Viale Milano, 26 36075 Montecchio Maggiore (VI) Veneto Italy Italy Active tert-butyl 3-oxobutanoate 216-904-5 1694-31-1 - View substance registered dossier
PROCOS SpA via Matteotti 249 28062 Cameri Piemonte Italy Italy Active Tert-butyl 3-Cyano-4-oxo-pyrrolidine-1-carboxylate 700-004-9 175463-32-8 - View substance registered dossier
[Confidential] - - - tert-butyl 3-[(2S)-3-[[(1S)-1-[[(1S,2S)-1-[[(1S)-2-[[2-[[2-[(2S)-2-[[(1S)-2-[[(1S)-2-[[2-[[(1S)-2-[(2S)-2-[(2S)-2-[(2S)-2-[[(1S)-2-amino-1-(tert-butoxymethyl)-2-oxo-ethyl]carbamoyl]pyrrolidine-1-carbonyl]pyrrolidine-1-carbonyl]pyrrolidin-1-yl]-1-methyl-2-oxo-ethyl]amino]-2-oxo-ethyl]amino]-1-(tert-butoxymethyl)-2-oxo-ethyl]amino]-1-(tert-butoxymethyl)-2-oxo-ethyl]carbamoyl]pyrrolidin-1-yl]-2-oxo-ethyl]amino]-2-oxo-ethyl]amino]-1-methyl-2-oxo-ethyl]carbamoyl]-2-methyl-butyl]carbamoyl]-3-methyl-butyl]amino]-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S,3S)-2-[[(2S)-2-[[(2S)-4-tert-butoxy-2-[[(2S)-2-[[2-[[(2S,3S)-2-[[(2S)-3-tert-butoxy-2-[[(2S)-2-[[(2S)-4-tert-butoxy-2-[[(2S)-3-tert-butoxy-2-[[(2S,3R)-3-tert-butoxy-2-[[(2S)-2-[[(2S,3R)-3-tert-butoxy-2-[[2-[[(2S)-5-tert-butoxy-2-[[2-[[(2S)-2-(tert-butoxycarbonylamino)-3-(4-tert-butoxyphenyl)propanoyl]amino]-2-methyl-propanoyl]amino]-5-oxo-pentanoyl]amino]acetyl]amino]butanoyl]amino]-3-phenyl-propanoyl]amino]butanoyl]amino]propanoyl]amino]-4-oxo-butanoyl]amino]-3-(4-tert-butoxyphenyl)propanoyl]amino]propanoyl]amino]-3-methyl-pentanoyl]amino]-2-methyl-propanoyl]amino]-4-methyl-pentanoyl]amino]-4-oxo-butanoyl]amino]-6-(tert-butoxycarbonylamino)hexanoyl]amino]-3-methyl-pentanoyl]amino]propanoyl]amino]-5-oxo-5-(tritylamino)pentanoyl]amino]-6-[[2-[2-[2-[[2-[2-[2-[[(4S)-5-tert-butoxy-4-[(20-tert-butoxy-20-oxo-icosanoyl)amino]-5-oxo-pentanoyl]amino]ethoxy]ethoxy]acetyl]amino]ethoxy]ethoxy]acetyl]amino]hexanoyl]amino]propanoyl]amino]-3-phenyl-propanoyl]amino]-3-methyl-butanoyl]amino]-5-oxo-5-(tritylamino)pentanoyl]amino]-3-oxo-propyl]indole-1-carboxylate 955-944-4 - - View substance registered dossier
[Confidential] - - - tert-butyl 3-[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-3-phenyl-propanoyl]amino]-3-methyl-butanoyl]amino]-5-oxo-5-(tritylamino)pentanoyl]amino]-3-[[(1S)-1-[[(1S,2S)-1-[[(1S)-2-(2-hydroxyethylamino)-1-methyl-2-oxo-ethyl]carbamoyl]-2-methyl-butyl]carbamoyl]-3-methyl-butyl]amino]-3-oxo-propyl]indole-1-carboxylate 874-918-2 2461524-68-3 - View substance registered dossier
ARKEMA Gmbh Tersteegenstrasse 28 40401 Düsseldorf Germany Germany Active tert-butyl 3,5,5-trimethylperoxyhexanoate 236-050-7 13122-18-4 2016; 2017 View substance registered dossier
PERGAN GmbH Schlavenhorst 71 46395 Bocholt NRW Germany Germany Active tert-butyl 3,5,5-trimethylperoxyhexanoate 236-050-7 13122-18-4 2017 View substance registered dossier
AKPA CHEMICAL IBERIA, S.L. AV DIAGONAL 601, 8 08028 Barcelona Spain Spain Active tert-butyl 3,5,5-trimethylperoxyhexanoate 236-050-7 13122-18-4 - View substance registered dossier
3M Belgium BVBA/SPRL (OR1) Hermeslaan 7 1831 Diegem Belgium Belgium Active tert-butyl 3,5,5-trimethylperoxyhexanoate 236-050-7 13122-18-4 2023 View substance registered dossier
Perga-Chem GmbH Vor dem Gröperntor 20 06484 Quedlinburg Germany Germany Active tert-butyl 3,5,5-trimethylperoxyhexanoate 236-050-7 13122-18-4 2017 View substance registered dossier
United Initiators GmbH Dr. Gustav-Adolph-Str. 3 D-82049 Pullach Bavaria Germany Germany Active tert-butyl 3,5,5-trimethylperoxyhexanoate 236-050-7 13122-18-4 2011; 2014; 2017; 2020; 2021; 2023 View substance registered dossier
Nouryon Chemicals NV/SA Parc Industriel de Ghlin Zone A 7011 Ghlin Mons Belgium Belgium Active tert-butyl 3,5,5-trimethylperoxyhexanoate 236-050-7 13122-18-4 2012; 2014; 2017; 2019 View substance registered dossier
Chr. Olesen ChemPharm GmbH Innungsstr. 3 21244 Buchholz Germany Germany Active tert-butyl 2-oxopyrrolidine-1-carboxylate 617-776-7 85909-08-6 - View substance registered dossier
MINAKEM Beuvry Production SAS 145, Chemin des Lilas 59310 Beuvry-la-Forêt France France Active tert-butyl 2-oxopyrrolidine-1-carboxylate 617-776-7 85909-08-6 2020 View substance registered dossier
PCAS 21 Chemin de la Sauvegarde 21 Ecully Parc - CS33167 69134 ECULLY France France Active tert-butyl 2-hydroxyisobutyrate 252-952-3 36293-63-7 - View substance registered dossier
ARKEMA Gmbh Tersteegenstrasse 28 40401 Düsseldorf Germany Germany Active tert-butyl 2-ethylperoxyhexanoate 221-110-7 3006-82-4 2016; 2017; 2019; 2022 View substance registered dossier
SCAS Europe S.A./N.V. Leonardo Da Vincilaan 19 B-1831 Diegem Belgium Belgium Active tert-butyl 2-ethylperoxyhexanoate 221-110-7 3006-82-4 - View substance registered dossier
United Initiators GmbH Dr. Gustav-Adolph-Str. 3 D-82049 Pullach Bavaria Germany Germany Active tert-butyl 2-ethylperoxyhexanoate 221-110-7 3006-82-4 2011; 2014; 2016; 2019; 2020; 2022 View substance registered dossier
3M Belgium BVBA/SPRL (OR1) Hermeslaan 7 1831 Diegem Belgium Belgium Active tert-butyl 2-ethylperoxyhexanoate 221-110-7 3006-82-4 - View substance registered dossier
Evonik Operations GmbH Rellinghauser Straße 1-11 45128 Essen Germany Germany Active tert-butyl 2-ethylperoxyhexanoate 221-110-7 3006-82-4 - View substance registered dossier
Perga-Chem GmbH Vor dem Gröperntor 20 06484 Quedlinburg Germany Germany Active tert-butyl 2-ethylperoxyhexanoate 221-110-7 3006-82-4 2013; 2017 View substance registered dossier
PERGAN GmbH Schlavenhorst 71 46395 Bocholt NRW Germany Germany Active tert-butyl 2-ethylperoxyhexanoate 221-110-7 3006-82-4 2016 View substance registered dossier
AKPA CHEMICAL IBERIA, S.L. AV DIAGONAL 601, 8 08028 Barcelona Spain Spain Active tert-butyl 2-ethylperoxyhexanoate 221-110-7 3006-82-4 - View substance registered dossier
Valspar b.v. Zuiveringweg 89 8243 PE Lelystad Netherlands Netherlands Active tert-butyl 2-ethylperoxyhexanoate 221-110-7 3006-82-4 2020 View substance registered dossier
Nouryon Chemicals NV/SA Parc Industriel de Ghlin Zone A 7011 Ghlin Mons Belgium Belgium Active tert-butyl 2-ethylperoxyhexanoate 221-110-7 3006-82-4 2012; 2013; 2017; 2019 View substance registered dossier
Axalta Coating Systems Germany GmbH & Co. KG Christbusch 25 42285 Wuppertal Germany Germany Active tert-butyl 2-ethylperoxyhexanoate 221-110-7 3006-82-4 - View substance registered dossier
DIPHARMA FRANCIS srl Bissone, 5 20021 Baranzate Milano Italy Italy Active tert-butyl 2-bromopropanoate 675-664-3 39149-80-9 - View substance registered dossier
TSE, OR for Tosoh Finechem Rembrandt Tower Amstelplein 1 1096 HA Amsterdam Netherlands Netherlands Active tert-butyl 2-bromopropanoate 675-664-3 39149-80-9 - View substance registered dossier
B-Lands Consulting (811725-2) 5 Place Robert Schuman - BP 1516 38025 Grenoble France France France Active tert-butyl 2-bromopropanoate 675-664-3 39149-80-9 - View substance registered dossier
Swords Laboratories Unlimited Company Cruiserath Road Mulhuddart D15H6EF Dublin 15 Co Dublin Ireland Ireland Active Tert-butyl 2-[4-(2-pyridinyl) phenylmethyl] hydrazine carboxylate 429-080-9 - 2010; 2017 View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant Italian competent national authority. - - Active Tert-butyl 2-[4-(2-pyridinyl) phenylmethyl] hydrazine carboxylate 429-080-9 - - View substance registered dossier
Curia Italy S.r.l. VIA DEL VECCHIO POLITECNICO, n. 9 20121 Milano Italy Italy Active Tert-butyl 2-[4-(2-pyridinyl) phenylmethyl] hydrazine carboxylate 429-080-9 - - View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant Irish competent national authority. - - Active Tert-butyl 2-[4-(2-pyridinyl) phenylmethyl] hydrazine carboxylate 429-080-9 - - View substance registered dossier
DSM Pharma Chemicals Venlo B.V. Grubbenvorsterweg 8 Postbox 81 5900 AB Venlo Netherlands Netherlands Active tert-butyl 2-[(4R,6S)-6-(hydroxymethyl)-2,2-dimethyl-1,3-dioxan-4-yl]acetate 432-960-5 124655-09-0 2014 View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant UK competent national authority. - - Active tert-butyl 2-[(4R,6S)-6-(hydroxymethyl)-2,2-dimethyl-1,3-dioxan-4-yl]acetate 432-960-5 124655-09-0 - View substance registered dossier
N.V. Ajinomoto OmniChem S.A. Cooppallaan 91 9230 Wetteren Oost-Vlaanderen Belgium Belgium Active tert-butyl 2-[(4R,6S)-6-(hydroxymethyl)-2,2-dimethyl-1,3-dioxan-4-yl]acetate 432-960-5 124655-09-0 2011 View substance registered dossier
EGIS Pharmaceuticals PLC Keresztúri út 30-38 H-1106 Budapest Hungary Hungary Active tert-butyl 2-[(4R,6R)-6-{2-[2-(4-fluorophenyl)-3-phenyl-4-(phenylcarbamoyl)-5-(propan-2-yl)-1H-pyrrol-1-yl]ethyl}-2,2-dimethyl-1,3-dioxan-4-yl]acetate 700-258-0 125971-95-1 - View substance registered dossier
Lek Pharmaceuticals d.d. Verovskova 57 1526 Ljubljana Slovenia Slovenia Active tert-butyl 2-[(4R,6R)-6-{2-[2-(4-fluorophenyl)-3-phenyl-4-(phenylcarbamoyl)-5-(propan-2-yl)-1H-pyrrol-1-yl]ethyl}-2,2-dimethyl-1,3-dioxan-4-yl]acetate 700-258-0 125971-95-1 2008; 2010 View substance registered dossier
ORIL INDUSTRIE 13 rue Auguste Desgenétais 76210 BOLBEC France France Active tert-butyl 2-[(4R,6R)-6-{2-[2-(4-fluorophenyl)-3-phenyl-4-(phenylcarbamoyl)-5-(propan-2-yl)-1H-pyrrol-1-yl]ethyl}-2,2-dimethyl-1,3-dioxan-4-yl]acetate 700-258-0 125971-95-1 2019; 2020; 2022 View substance registered dossier
Krka, d. d., Novo mesto Smarjeska cesta 6 SI-8501 Novo mesto Slovenia Slovenia Active tert-butyl 2-[(4R,6R)-6-{2-[2-(4-fluorophenyl)-3-phenyl-4-(phenylcarbamoyl)-5-(propan-2-yl)-1H-pyrrol-1-yl]ethyl}-2,2-dimethyl-1,3-dioxan-4-yl]acetate 700-258-0 125971-95-1 2018 View substance registered dossier
Gedeon Richter Plc. Gyomroi ut 19-21 1103 Budapest Hungary Hungary Active tert-butyl 2-[(4R,6R)-6-{2-[2-(4-fluorophenyl)-3-phenyl-4-(phenylcarbamoyl)-5-(propan-2-yl)-1H-pyrrol-1-yl]ethyl}-2,2-dimethyl-1,3-dioxan-4-yl]acetate 700-258-0 125971-95-1 - View substance registered dossier
DKSH France S.A. 1475 Quai du Rhone 01702 Miribel France France Active tert-butyl 2-[(4R,6R)-6-{2-[2-(4-fluorophenyl)-3-phenyl-4-(phenylcarbamoyl)-5-(propan-2-yl)-1H-pyrrol-1-yl]ethyl}-2,2-dimethyl-1,3-dioxan-4-yl]acetate 700-258-0 125971-95-1 - View substance registered dossier
Saneca Pharmaceuticals a.s. Nitrianska 100 92027 Hlohovec Slovakia Slovakia Active tert-butyl 2-[(4R,6R)-6-{2-[2-(4-fluorophenyl)-3-phenyl-4-(phenylcarbamoyl)-5-(propan-2-yl)-1H-pyrrol-1-yl]ethyl}-2,2-dimethyl-1,3-dioxan-4-yl]acetate 700-258-0 125971-95-1 2011 View substance registered dossier
MINAKEM Beuvry Production SAS 145, Chemin des Lilas 59310 Beuvry-la-Forêt France France Active tert-butyl 2-[(2S,3S)-2-(benzyloxy)pentan-3-yl]hydrazinecarboxylate 606-022-2 184177-88-6 - View substance registered dossier
Lek Pharmaceuticals d.d. Verovskova 57 1526 Ljubljana Slovenia Slovenia Active tert-butyl 2-((4R,6S)-6-((E)-2-(4-(4-fluorophenyl)-6-isopropyl-2-(N-methylmethylsulfonamido)pyrimidin-5-yl)vinyl)-2,2-dimethyl-1,3-dioxan-4-yl)acetate 432-810-9 - - View substance registered dossier
N.V. Ajinomoto OmniChem S.A. Cooppallaan 91 9230 Wetteren Oost-Vlaanderen Belgium Belgium Active tert-butyl 2-((4R,6S)-6-((E)-2-(4-(4-fluorophenyl)-6-isopropyl-2-(N-methylmethylsulfonamido)pyrimidin-5-yl)vinyl)-2,2-dimethyl-1,3-dioxan-4-yl)acetate 432-810-9 - 2010; 2012; 2018; 2020 View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant UK competent national authority. - - Active tert-butyl 2-((4R,6S)-6-((E)-2-(4-(4-fluorophenyl)-6-isopropyl-2-(N-methylmethylsulfonamido)pyrimidin-5-yl)vinyl)-2,2-dimethyl-1,3-dioxan-4-yl)acetate 432-810-9 - - View substance registered dossier
Avara Avlon Pharma Services Ltd Avlon Works Severn Road, Hallen BS10 7ZE Bristol United Kingdom United Kingdom No longer Valid tert-butyl 2-((4R,6S)-6-((E)-2-(4-(4-fluorophenyl)-6-isopropyl-2-(N-methylmethylsulfonamido)pyrimidin-5-yl)vinyl)-2,2-dimethyl-1,3-dioxan-4-yl)acetate 432-810-9 - 2021 View substance registered dossier
[Confidential] - - - tert-butyl 2-((1H-pyrrolo[2,3-b]pyridin-5-yl)oxy)-4-bromobenzoate 942-459-8 1628047-84-6 - View substance registered dossier
Minakem Dunkerque Production 224 avenue de la Dordogne Zone d'entreprises du Nord Gracht 59640 DUNKERQUE France France Active tert-butyl 1H-pyrrol-1-ylcarbamate 810-523-3 937046-95-2 - View substance registered dossier
MINAKEM Beuvry Production SAS 145, Chemin des Lilas 59310 Beuvry-la-Forêt France France Cease Manufacture tert-butyl 1H-pyrrol-1-ylcarbamate 810-523-3 937046-95-2 2016 View substance registered dossier
Glaxo Operations UK Glaxo Wellcome House Berkeley Avenue UB6 0NN Greenford Middlesex United Kingdom United Kingdom No longer Valid tert-butyl (triphenylphosphoranylidene) acetate 412-880-7 35000-38-5 2021 View substance registered dossier
Evonik Operations GmbH Rellinghauser Straße 1-11 45128 Essen Germany Germany Active tert-butyl (triphenylphosphoranylidene) acetate 412-880-7 35000-38-5 2011 View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant UK competent national authority. - - Active tert-butyl (triphenylphosphoranylidene) acetate 412-880-7 35000-38-5 - View substance registered dossier
[Confidential] - - - tert-butyl (S)-2-carbamoylpyrrolidine-1-carboxylate 626-262-1 35150-07-3 - View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant Dutch competent national authority. - - Active tert-butyl (5S,6R,7R)-3-bromomethyl-5,8-dioxo-7-(2-phenylacetamido)-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate 407-620-4 33610-13-8 - View substance registered dossier
Krka, d. d., Novo mesto Smarjeska cesta 6 SI-8501 Novo mesto Slovenia Slovenia Active tert-butyl (4R)-cis-6-cyanomethyl-2,2-dimethyl-1,3-dioxane-4-acetate 425-780-3 125971-94-0 - View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant Irish competent national authority. - - Active tert-butyl (4R)-cis-6-cyanomethyl-2,2-dimethyl-1,3-dioxane-4-acetate 425-780-3 125971-94-0 - View substance registered dossier
Minakem Dunkerque Production 224 avenue de la Dordogne Zone d'entreprises du Nord Gracht 59640 DUNKERQUE France France Active tert-butyl (4-bromo-2-cyano-1H-pyrrol-1-yl)carbamate 810-525-4 937047-04-6 - View substance registered dossier
MINAKEM Beuvry Production SAS 145, Chemin des Lilas 59310 Beuvry-la-Forêt France France Cease Manufacture tert-butyl (4-bromo-2-cyano-1H-pyrrol-1-yl)carbamate 810-525-4 937047-04-6 2016 View substance registered dossier
Patheon Austria GmbH & Co KG St. Peterstrasse 25 A-4020 Linz Austria Austria Active tert-butyl (3S,6S)-3-((tert-butyldimethylsilyl)oxy)-6-chloro-6-((3aS,4S,6S,7aR)-3a,5,5-trimethylhexahydro-4,6-methanobenzo[d][1,3,2]dioxaborol-2-yl)hexanoate 811-363-7 1681053-96-2 - View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant Irish competent national authority. - - No longer Valid tert-butyl (3S,5S)-3-isopropyl-5-((2S,4S)-tetrahydro-4-isopropyl-5-oxo-furan-2-yl)-2-oxo-pyrrolidine-carboxylate 472-680-0 - 2022 View substance registered dossier
Flamma S.p.a. via Bedeschi, 22 24040 Chignolo d'Isola Bergamo Italy Italy Active tert-butyl (3S)-3-hydroxypiperidine-1-carboxylate 626-373-5 143900-44-1 - View substance registered dossier
Lek Pharmaceuticals d.d. Verovskova 57 1526 Ljubljana Slovenia Slovenia Active tert-butyl (3R,5S,6E)-7-[4-(4-fluorophenyl)-2-(N-methylmethanesulfonamido)-6-(propan-2-yl)pyrimidin-5-yl]-3,5-dihydroxyhept-6-enoate 609-144-4 355806-00-7 2020 View substance registered dossier
EGIS Pharmaceuticals PLC Keresztúri út 30-38 H-1106 Budapest Hungary Hungary Active tert-butyl (3R,5S,6E)-7-[4-(4-fluorophenyl)-2-(N-methylmethanesulfonamido)-6-(propan-2-yl)pyrimidin-5-yl]-3,5-dihydroxyhept-6-enoate 609-144-4 355806-00-7 - View substance registered dossier
Flamma S.p.a. via Bedeschi, 22 24040 Chignolo d'Isola Bergamo Italy Italy Active tert-butyl (3R)-3-{3-iodo-4-[(triphenylphosphanylidene)amino]-1H-pyrazolo[3,4-d]pyrimidin-1-yl}piperidine-1-carboxylate 953-572-7 - - View substance registered dossier
F.I.S. Fabbrica Italiana Sintetici S.p.a. Viale Milano, 26 36075 Montecchio Maggiore (VI) Veneto Italy Italy Active tert-butyl (2S,4S)-2-[4-(2-{(2S,5S)-1-[N-(methoxycarbonyl)-L-valyl]-5-methylpyrrolidin-2-yl}-1,11-dihydroisochromeno[4',3':6,7]naphtho[1,2-d]imidazol-9-yl)-1H-imidazol-2-yl]-4-(methoxymethyl)pyrrolidine-1-carboxylate 807-100-0 1378391-45-7 - View substance registered dossier
Swords Laboratories Unlimited Company Cruiserath Road Mulhuddart D15H6EF Dublin 15 Co Dublin Ireland Ireland Active tert-butyl (2S)-2-{5-[4-(4-{2-[(2S)-1-[(tert-butoxy)carbonyl]pyrrolidin-2-yl]-1H-imidazol-5-yl}phenyl)phenyl]-1H-imidazol-2-yl}pyrrolidine-1-carboxylate 941-432-8 - - View substance registered dossier
[Confidential] - - - tert-butyl (2S)-2-carbamoyl-2,3-dihydropyrrole-1-carboxylate 615-204-0 709031-38-9 - View substance registered dossier
DIPHARMA FRANCIS srl Bissone, 5 20021 Baranzate Milano Italy Italy Active tert-butyl (2S)-2-(3-fluoro-4-phenylphenyl)propanoate 945-962-0 - - View substance registered dossier
MINAKEM Beuvry Production SAS 145, Chemin des Lilas 59310 Beuvry-la-Forêt France France Cease Manufacture tert-butyl (2-cyano-1H-pyrrol-1-yl)carbamate 810-524-9 937046-96-3 2016 View substance registered dossier
Minakem Dunkerque Production 224 avenue de la Dordogne Zone d'entreprises du Nord Gracht 59640 DUNKERQUE France France Active tert-butyl (2-cyano-1H-pyrrol-1-yl)carbamate 810-524-9 937046-96-3 - View substance registered dossier
[Confidential] - - - tert-butyl (1S,3S,5S)-3-carbamoyl-2-azabicyclo[3.1.0]hexane-2-carboxylate 609-213-9 361440-67-7 - View substance registered dossier

In this table, you will find all public data submitted to ECHA in REACH registration dossiers by substance manufacturers, importers, or their representatives, as laid out by the REACH Regulation (see Understanding REACH regulation).

ECHA makes available this information as REACH registered substance factsheets, which contain the full set of non-confidential information from related registration dossiers for a substance. Depending on the number of registrations that have been made for a substance, one factsheet can thus represent data from anything between hundreds of registration dossiers in a joint submission, to data from just one registration dossier.

As noted in the Legal Notice of the ECHA website, ECHA does not give any guarantees or warranties regarding the quality and correctness of the published information. The information in the portal is published ‘as provided’ by industry, and its accuracy has not been verified by ECHA. ECHA is also not in a position to intervene with, edit or correct the published data; this can only be done by the registrant responsible for its submission. Please also note that the information may be protected and its use may require prior permission from its owner (see the ECHA website Legal Notice more details).

In the portal results table are presented:

  • Public substance identity – the best available non-confidential substance name, EC, and CAS numbers.
  • Registration status – indicating the calculated registration status for the whole factsheet: Active – is being manufactured or imported to the EEA by one or more registrants; Cease Manufacture - is no longer being manufactured or imported above 1 tone per calendar year. All registrants of the substance have reported a cease of manufacture or import; or No longer valid - no longer considered registered under REACH and not currently allowed to be manufactured or imported to the EEA, until the substance is registered again.
  • Registration type – indicating whether a given factsheet contains data from a REACH full registration, REACH intermediate registration, or only a limited set of data inherited from a NONS notification.
  • Submission type – indicating whether the data in a given factsheet was submitted jointly or individually.
  • Total tonnage band – calculated per factsheet from all contributing registrations, based on the estimated quantity of the substance placed on the market. Data is excluded from dossiers where the tonnage is claimed confidential, from Intermediate registration dossiers, and from NONs which have not been updated.
  • Last updated – indicating the date on which this registered substance factsheet was last modified with new or updated data, based on an industry submission.
  • Link to the full factsheet.

A subset of the key chemical properties (physico-chemical, environmental fate, ecotoxicological and toxicological data) of registered substances can be searched and accessed via the OECD eChemPortal.