Registered substances

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New Data Availability System

A new Data Availability System is being developed by ECHA. To begin with this system will take over the responsibility of making REACH registration data available, once it is ready. We expect the first version to be publicly available by the end of 2023.

Since ECHA aims to devote our maximum effort to this new system, we can no longer maintain REACH registration data on the current Dissemination Platform. As such once the IUCLID format change begins on 19th May 2023 we will no longer update REACH registered substance factsheets. The factsheets will remain online, but will not be updated.

New and updated REACH registration submissions, as well as all registrations on file, will be made available in the new system when it is ready. We will inform you of what you can expect in the new system, along with details of when and where to find it.

We appreciate your understanding in the meantime.

DISSEMINATION
PLATFORM

REACH - Registration, Evaluation, Authorisation and Restriction of Chemicals Regulation

Registered Substances Factsheets

Substances which have been registered and can be placed on the EEA market by those companies with a valid registration



No results were found
Details
(1R, 3r, 5S)-3-hydroxyspiro[8-azoniabicyclo[3.2.1]octane-8,1’-pyrrolidinium]chloride
609-015-2 3464-71-9 Active Intermediate Joint Intermediate use only 12-03-2018 View substance registered dossier
(1R, 4R, 5S) 4-hydroxy-6,6-dimethyl-3-Oxabicyclo[3.1.0]hexan-2-one
619-753-7 73611-02-6 Active Intermediate Joint Intermediate use only 12-05-2014 View substance registered dossier
(1R,11aS)-1-acetyl-11a-methyl-2,3,3a,3b,4,5,6,8,9,11-decahydrospiro[cyclopenta[a]phenanthrene-7,2'-[1,3]dioxolan]-1-yl acetate
607-316-3 240806-31-9 Active Intermediate Joint Intermediate use only 19-06-2018 View substance registered dossier
(1R,11aS)-1-hydroxy-11a-methyl-2,3,3a,5,6,8,9,11-octahydrospiro[cyclopenta[a]phenanthrene-7,2'-[1,3]dioxolane]-1-carbonitrile
608-856-2 33300-19-5 Active Intermediate Joint Intermediate use only 19-06-2018 View substance registered dossier
(1R,2R)-1,2-Cyclohexanedimethanol
692-053-7 65376-05-8 Active Intermediate Joint Intermediate use only 24-10-2018 View substance registered dossier
(1R,2R)-1,3-Dihydroxy-1-(4-nitrophenyl)propyl-2-ammonium (1R, 5S)-5-(dimethylphenylsilyl)-2-(hydroxymethyl)cyclopent-2-ene-1-carboxylate
445-910-2 649761-22-8 Active Full Joint ≥ 1 to < 10 tonnes 14-10-2016 View substance registered dossier
(1R,2R)-1-amino-2-difluoromethyl)-N- (1-methylcyclopropylsulfonyl)cyclo propanecarboxyamide hydrochloride
943-460-6 1360828-80-3 Active Intermediate Joint Intermediate use only 16-06-2020 View substance registered dossier
(1R,2R)-cyclohexane-1,2-diamine (2R,3R)-2,3-dihydroxybutanedioic acid
609-759-8 39961-95-0 Active Intermediate Joint Intermediate use only 29-01-2018 View substance registered dossier
(1R,2R,3S,4S)-1-(1,1,3,3-tetraoxido-1,3-dithian-2-yl)pentane-1,2,3,4-tetrol
936-126-6 1352707-53-9 Active Intermediate Joint Intermediate use only 16-02-2018 View substance registered dossier
(1R,2R,3S,4S)-1-(1,3-dithian-2-yl)pentane-1,2,3,4-tetrol
936-125-0 1352707-52-8 Active Intermediate Joint Intermediate use only 16-02-2018 View substance registered dossier
(1R,2R,4S)-1,3,3-trimethylbicyclo[2.2.1]heptan-2-ol
606-948-7 2217-02-9 Active Full Joint ≥ 10 to < 100 tonnes 20-07-2020 View substance registered dossier
(1R,2R,4S)-1,3,3-trimethylbicyclo[2.2.1]heptan-2-yl acetate
807-751-0 4057-31-2 Active Full Joint ≥ 10 to < 100 tonnes 07-05-2018 View substance registered dossier
(1R,2S)-1-(2-amino-4-oxo-3,4-dihydropteridin-6-yl)propane-1,2-diyl diacetate
887-376-7 62933-57-7 Active Intermediate Joint Intermediate use only 14-12-2022 View substance registered dossier
(1R,2S)-1-[(Cyclopropanesulfonyl)carbamoyl]-2-ethenylcyclopropan-1-aminium 4-methylbenzenesulfonate
801-606-5 1028252-16-5 Active Intermediate Joint Intermediate use only 11-05-2017 View substance registered dossier
(1R,2S)-1-phenyl-2-pyrrolidin-1-yl-propan-1-ol;hydrochloride
606-696-8 210558-66-0 Active Intermediate Joint Intermediate use only 06-09-2017 View substance registered dossier
(1R,2S)-2,6-dimethyl-2,3-dihydro-1H-inden-1-amine
700-140-9 - Active Intermediate Joint Intermediate use only 15-03-2023 View substance registered dossier
(1R,2S)-2-ethenyl-1-(ethoxycarbonyl)cyclopropanaminium (2S)-2-[(4-chlorobenzoyl)oxy]propanoate
816-798-6 1352613-22-9 Active Intermediate Joint Intermediate use only 22-10-2021 View substance registered dossier
(1R,2S)-cyclohexane-1,2-diamine; sulfuric acid
613-794-4 65433-80-9 Active Intermediate Joint Intermediate use only 13-04-2018 View substance registered dossier
(1R,2S,10R,11S,15S)-2,15-dimethyl-4-(morpholin-4-yl)-13-(pyrrolidin-1-yl)tetracyclo[8.7.0.0²,⁷.0¹¹,¹⁵]heptadecane-5,14-diol
601-595-5 119302-20-4 Active Intermediate Joint Intermediate use only 31-05-2018 View substance registered dossier
(1R,2S,2'S,4R)-1,7,7-Trimethylbicyclo (2.2.1)heptane-2-spiro-4'-(2'-isopropyl-1',3'-dioxane)
443-460-1 - Active Full Joint ≥ 1 tonnes 05-07-2012 View substance registered dossier
(1R,2S,3S,4R)-3-((2-chloro-5-fluoropyrimidin-4-yl)amino)bicyclo[2.2.2]octane-2-carboxylic acid
821-184-6 1777721-60-4 Cease Manufacture Full Joint Cease manufacture 28-02-2019 View substance registered dossier
(1R,2S,3S,4R)-3-((5-fluoro-2-(5-fluoro-1-tosyl-1H-pyrrolo[2,3-b]pyridin-3-yl)pyrimidin-4-yl)amino)bicyclo[2.2.2]octane-2-carboxylic acid
821-185-1 1777721-63-7 Cease Manufacture Full Joint Cease manufacture 28-02-2019 View substance registered dossier
(1R,2S,5R)-2-Isopropyl-5-methylcyclohexyl (2R,5R)-5-hydroxy-1,3-oxathiolane-2-carboxylate
604-569-1 147126-62-3 Cease Manufacture Intermediate Joint Cease manufacture 13-08-2014 View substance registered dossier
(1R,2S,5R)-2-Isopropyl-5-methylcyclohexyl (2R,5R)-5-hydroxy-1,3-oxathiolane-2-carboxylate
604-569-1 147126-62-3 Active Intermediate Joint Intermediate use only 24-01-2022 View substance registered dossier
(1R,2S,5R)-2-isopropyl-N-(4-methoxyphenyl)-5-methylcyclohexanecarboxamide
700-232-9 68489-09-8 Active Full Joint ≥ 1 to < 10 tonnes 25-05-2016 View substance registered dossier
(1R,2S,5R)-5-methyl-2-(propan-2-yl)cyclohexyl (ethylamino)(oxo)acetate
700-185-4 1122460-01-8 Active Full Joint ≥ 1 to < 10 tonnes 17-12-2012 View substance registered dossier
(1R,2S,5S)-6,6-dimethyl-3-[3-methyl-N-(trifluoroacetyl)-L-valyl]-3-azabicyclo[3.1.0]hexane-2-carboxylic acid
955-024-2 2755812-45-2 Active Intermediate Joint Intermediate use only 07-12-2022 View substance registered dossier
(1R,2S,6R,7S)-4-azatricyclo[5.2.1.0^{2,6}]decane-3,5-dione
689-268-3 14805-29-9 Active Intermediate Joint Intermediate use only 31-10-2018 View substance registered dossier
(1R,2S,6R,7S)-4-{[(1R,2R)-2-{[4-(1,2-benzothiazol-3- yl)piperazin-1-yl]methyl}-cyclohexyl]methyl}-4- azatricyclo[5.2.1.0^{2,6}]decane-3,5-dione
696-042-8 367514-87-2 Active Intermediate Joint Intermediate use only 25-10-2018 View substance registered dossier
(1R,2S,8S,10S,11S,13R,14R,15S,17S)-1,8-difluoro- 14,17dihydroxy-2,13,15-trimethyl-5-oxotetracyclo[8.7.0.0^{2,7}.0^{11,15}]heptadeca-3,6-diene-14-carbothioic S-acid
617-081-9 80473-92-3 Cease Manufacture Full Joint Cease manufacture 21-11-2016 View substance registered dossier
(1R,3R)-Methyl-1,2,3,4-tetrahydro-2-chloroacetyl-1-(3,4-methylenedioxyphenyl)-9H-pyrido[3,4-b]indole-3-carboxylate
689-794-3 171489-59-1 Active Intermediate Joint Intermediate use only 09-10-2020 View substance registered dossier
(1R,3S)-2,2-Dimethyl-3-(2-oxopropyl)cyclopropanecarboxylic acid
615-083-4 70223-33-5 Active Intermediate Joint Intermediate use only 30-04-2013 View substance registered dossier
(1R,3S)-3-aminocyclopentan-1-ol benzoate
946-279-0 1846582-38-4 Active Intermediate Joint Intermediate use only 20-06-2018 View substance registered dossier
(1R,3S,4S,5S)-4,6,6-trimethylspiro[bicyclo[3.1.1]heptane-3,4'-cyclohex-2-ene]-1'-one
430-460-1 133636-82-5 Active NONS Joint Tonnage data confidential 22-11-2012 View substance registered dossier
(1R,3s,5S)-8-benzyl-3-(3-isopropyl-5-methyl-4H-1,2,4-triazol-4-yl)-8-azabicyclo[3.2.1]octane
447-620-1 - Active Intermediate Joint Intermediate use only 13-07-2018 View substance registered dossier
(1R,3s,5S)-8-benzyl-3-(3-isopropyl-5-methyl-4H-1,2,4-triazol-4-yl)-8-azabicyclo[3.2.1]octane
447-620-1 - Active NONS Joint Tonnage data confidential 07-10-2010 View substance registered dossier
(1R,4aS,8R,8aS)-2,2,6,8-tetramethyl-1,2,3,4,4a,5,8,8a-octahydronaphthalen-1-ol
434-960-0 103614-86-4 Active NONS Joint Tonnage data confidential 10-01-2011 View substance registered dossier
(1R,4R,5S)- 4-(1,1-Dichloro-2,2,2-trifluoroethyl)-6,6-dimethyl-3-oxabicyclo[3.1.0]hexan-2-one
606-114-2 187592-70-7 Active Intermediate Joint Intermediate use only 16-09-2013 View substance registered dossier
(1R,4S)-2-azabicyclo[2.2.1]hept-5-en-3-one
1418U90
418-530-1 79200-56-9 Active Intermediate Joint Intermediate use only 29-03-2021 View substance registered dossier
(1R,4S)-2-azabicyclo[2.2.1]hept-5-en-3-one
1418U90
418-530-1 79200-56-9 Active NONS Joint Tonnage data confidential 10-11-2008 View substance registered dossier
(1R,4S)-2-azabicyclo[2.2.1]hept-5-en-3-one
616-668-7 79200-56-9 Active Intermediate Joint Intermediate use only 10-01-2018 View substance registered dossier
(1R,4S)-6-tert-butoxy-4-(tert-butyldimethylsilyloxy)-6-oxo-1-(2-(thiophen-2-yl)acetamido)hexylboronic acid, (+)-pinanediol ester
812-137-0 1681053-97-3 Active Intermediate Joint Intermediate use only 02-05-2018 View substance registered dossier
(1R,4S,4aR,8aS)-9-(dichloromethylidene)octahydro-1,4-methanonaphthalene-5,8-dione
700-729-0 - Active Intermediate Joint Intermediate use only 08-12-2020 View substance registered dossier
(1R,4S,4aS,8aR)-9-(dichloromethylene)-1,4,4a,8a-tetrahydro-1,4-methanonaphthalene-5,8-dione
807-377-8 1263184-85-5 Cease Manufacture Intermediate Joint Cease manufacture 21-08-2017 View substance registered dossier
(1R,5aR,10R,11aS)-1-acetyl-10-[4-(dimethylamino)phenyl]-5a-hydroxy-11a-methyl-3,3a,3b,4,5,6,8,9,10,11-decahydro-2H-spiro[cyclopenta[a]phenanthrene-7,2'-[1,3]dioxolan]-1-yl acetate
615-905-1 730962-28-4 Active Intermediate Joint Intermediate use only 19-06-2018 View substance registered dossier
(1R,5R)-2,6,6-trimethylbicyclo[3.1.1]hept-2-ene
232-087-8 7785-70-8 Active Full Joint ≥ 10 to < 100 tonnes 18-12-2019 View substance registered dossier
(1R,5S)-2-(6,6-dimethylbicyclo[3.1.1]hept-2-en-2-yl) ethyl acetate
800-940-9 35836-72-7 Active Full Joint ≥ 100 to < 1 000 tonnes 13-04-2022 View substance registered dossier
(1R,5S)-8-benzyl-8-azabicyclo[3.2.1]octan-3-one hydrochloride
617-458-8 83393-23-1 Active Intermediate Joint Intermediate use only 16-12-2015 View substance registered dossier
(1R,5S,E)-8-benzyl-8-azabicyclo[3.2.1]octan-3-one oxime
616-314-1 76272-34-9 Active Intermediate Joint Intermediate use only 25-01-2019 View substance registered dossier
(1R,6S)- 4,7,7-Trimethyl-3-oxabicyclo[4.1.0]hept-4-en-2-one
615-077-1 70174-49-1 Active Intermediate Joint Intermediate use only 16-09-2013 View substance registered dossier
No results were found
Registrant/Supplier Address Country Registration Status Name EC / List no. CAS no. Last update year Details
PROCOS SpA via Matteotti 249 28062 Cameri Piemonte Italy Italy Active (1R, 3r, 5S)-3-hydroxyspiro[8-azoniabicyclo[3.2.1]octane-8,1’-pyrrolidinium]chloride 609-015-2 3464-71-9 - View substance registered dossier
[Confidential] - - - (1R, 4R, 5S) 4-hydroxy-6,6-dimethyl-3-Oxabicyclo[3.1.0]hexan-2-one 619-753-7 73611-02-6 - View substance registered dossier
CURIA SPAIN, S.A.U. Parque Tecnológico de Boecillo, parcela 105 47151 Boecillo Valladolid Spain Spain Active (1R,11aS)-1-acetyl-11a-methyl-2,3,3a,3b,4,5,6,8,9,11-decahydrospiro[cyclopenta[a]phenanthrene-7,2'-[1,3]dioxolan]-1-yl acetate 607-316-3 240806-31-9 2018 View substance registered dossier
CURIA SPAIN, S.A.U. Parque Tecnológico de Boecillo, parcela 105 47151 Boecillo Valladolid Spain Spain Active (1R,11aS)-1-hydroxy-11a-methyl-2,3,3a,5,6,8,9,11-octahydrospiro[cyclopenta[a]phenanthrene-7,2'-[1,3]dioxolane]-1-carbonitrile 608-856-2 33300-19-5 2018 View substance registered dossier
Pliva Hrvatska doo Prilaz baruna Filipovića 25 10000 Zagreb Croatia Croatia Active (1R,2R)-1,2-Cyclohexanedimethanol 692-053-7 65376-05-8 - View substance registered dossier
Hovione FarmaCiencia SA Sete Casas 2674-506 Loures Portugal Portugal Active (1R,2R)-1,3-Dihydroxy-1-(4-nitrophenyl)propyl-2-ammonium (1R, 5S)-5-(dimethylphenylsilyl)-2-(hydroxymethyl)cyclopent-2-ene-1-carboxylate 445-910-2 649761-22-8 2010; 2011; 2012; 2014 View substance registered dossier
Swords Laboratories Unlimited Company Cruiserath Road Mulhuddart D15H6EF Dublin 15 Co Dublin Ireland Ireland Active (1R,2R)-1,3-Dihydroxy-1-(4-nitrophenyl)propyl-2-ammonium (1R, 5S)-5-(dimethylphenylsilyl)-2-(hydroxymethyl)cyclopent-2-ene-1-carboxylate 445-910-2 649761-22-8 2010; 2012; 2014; 2016 View substance registered dossier
AbbVie Srl S.R. 148 Pontina Km 52 snc 04011 Campoverde di Aprilia (LT) Italy Italy Active (1R,2R)-1-amino-2-difluoromethyl)-N- (1-methylcyclopropylsulfonyl)cyclo propanecarboxyamide hydrochloride 943-460-6 1360828-80-3 2020 View substance registered dossier
AbbVie Ireland NL B.V. Manorhamilton Road none Sligo Ireland Ireland Active (1R,2R)-1-amino-2-difluoromethyl)-N- (1-methylcyclopropylsulfonyl)cyclo propanecarboxyamide hydrochloride 943-460-6 1360828-80-3 - View substance registered dossier
AbbVie Logistics B.V. Zuiderzeelaan 53 8017 JV Zwolle Netherlands Netherlands Active (1R,2R)-1-amino-2-difluoromethyl)-N- (1-methylcyclopropylsulfonyl)cyclo propanecarboxyamide hydrochloride 943-460-6 1360828-80-3 - View substance registered dossier
Arran Chemical Company Ltd Monksland Industrial Estate N37DN24 Athlone Co. Roscommon Ireland Ireland Active (1R,2R)-cyclohexane-1,2-diamine (2R,3R)-2,3-dihydroxybutanedioic acid 609-759-8 39961-95-0 - View substance registered dossier
DIPHARMA FRANCIS srl Bissone, 5 20021 Baranzate Milano Italy Italy Active (1R,2R,3S,4S)-1-(1,1,3,3-tetraoxido-1,3-dithian-2-yl)pentane-1,2,3,4-tetrol 936-126-6 1352707-53-9 - View substance registered dossier
DIPHARMA FRANCIS srl Bissone, 5 20021 Baranzate Milano Italy Italy Active (1R,2R,3S,4S)-1-(1,3-dithian-2-yl)pentane-1,2,3,4-tetrol 936-125-0 1352707-52-8 - View substance registered dossier
Destilerías Muñoz Gálvez, S.A. Avda. Ciudad de Almería, 162 E30010 Murcia Murcia Spain Spain Active (1R,2R,4S)-1,3,3-trimethylbicyclo[2.2.1]heptan-2-ol 606-948-7 2217-02-9 2018 View substance registered dossier
TAKASAGO TICSA-Producer/Importer Avenida de Mazarrón, 49 30120 El Palmar Murcia Spain Spain Active (1R,2R,4S)-1,3,3-trimethylbicyclo[2.2.1]heptan-2-ol 606-948-7 2217-02-9 - View substance registered dossier
DESTILACIONES BORDAS CHINCHURRETA, S.A. C/ Acueducto, 4-6 Pol. Ind. Ctra la Isla 41703 Dos Hermanas (Sevilla) Spain Spain Active (1R,2R,4S)-1,3,3-trimethylbicyclo[2.2.1]heptan-2-ol 606-948-7 2217-02-9 2019 View substance registered dossier
LLUCH ESSENCE, S.L.U. Lo Gaiter, 160 08820 EL PRAT DE LLOBREGAT CATALUÑA Spain Spain Active (1R,2R,4S)-1,3,3-trimethylbicyclo[2.2.1]heptan-2-ol 606-948-7 2217-02-9 - View substance registered dossier
ERNESTO VENTOS, S.A. Carretera Reial 120B 08960 Sant Just Desvern Spain Spain Active (1R,2R,4S)-1,3,3-trimethylbicyclo[2.2.1]heptan-2-ol 606-948-7 2217-02-9 - View substance registered dossier
Destilerías Muñoz Gálvez, S.A. Avda. Ciudad de Almería, 162 E30010 Murcia Murcia Spain Spain Active (1R,2R,4S)-1,3,3-trimethylbicyclo[2.2.1]heptan-2-yl acetate 807-751-0 4057-31-2 - View substance registered dossier
DESTILACIONES BORDAS CHINCHURRETA, S.A. C/ Acueducto, 4-6 Pol. Ind. Ctra la Isla 41703 Dos Hermanas (Sevilla) Spain Spain Active (1R,2R,4S)-1,3,3-trimethylbicyclo[2.2.1]heptan-2-yl acetate 807-751-0 4057-31-2 - View substance registered dossier
DIPHARMA FRANCIS srl Bissone, 5 20021 Baranzate Milano Italy Italy Active (1R,2S)-1-(2-amino-4-oxo-3,4-dihydropteridin-6-yl)propane-1,2-diyl diacetate 887-376-7 62933-57-7 - View substance registered dossier
MSD International GmbH (Ballydine Branch) Ballydine - Kilsheelan 0 Clonmel Ireland Ireland Active (1R,2S)-1-[(Cyclopropanesulfonyl)carbamoyl]-2-ethenylcyclopropan-1-aminium 4-methylbenzenesulfonate 801-606-5 1028252-16-5 - View substance registered dossier
Siegfried St. Vulbas SAS 530, allée de la Luye 01150 SAINT VULBAS France France Active (1R,2S)-1-phenyl-2-pyrrolidin-1-yl-propan-1-ol;hydrochloride 606-696-8 210558-66-0 - View substance registered dossier
BASF SE Carl-Bosch-Str. 38 67056 Ludwigshafen am Rhein Rheinland-Pfalz Germany Germany Active (1R,2S)-2,6-dimethyl-2,3-dihydro-1H-inden-1-amine 700-140-9 - 2011; 2019; 2020 View substance registered dossier
Bayer AG Kaiser-Wilhelm-Allee 1 51373 Leverkusen Germany Germany Active (1R,2S)-2,6-dimethyl-2,3-dihydro-1H-inden-1-amine 700-140-9 - 2011; 2023 View substance registered dossier
A.C.R.A.F. Spa Via Amelia 70 00181 Roma Italy Italy Active (1R,2S)-2-ethenyl-1-(ethoxycarbonyl)cyclopropanaminium (2S)-2-[(4-chlorobenzoyl)oxy]propanoate 816-798-6 1352613-22-9 2021 View substance registered dossier
Arran Chemical Company Ltd Monksland Industrial Estate N37DN24 Athlone Co. Roscommon Ireland Ireland Active (1R,2S)-cyclohexane-1,2-diamine; sulfuric acid 613-794-4 65433-80-9 - View substance registered dossier
FARMHISPANIA S.A. Passeig del Riu Besós, 9-10 08160 Montmeló Barcelona Spain Spain Active (1R,2S,10R,11S,15S)-2,15-dimethyl-4-(morpholin-4-yl)-13-(pyrrolidin-1-yl)tetracyclo[8.7.0.0²,⁷.0¹¹,¹⁵]heptadecane-5,14-diol 601-595-5 119302-20-4 - View substance registered dossier
CHEMICAL INSPECTION & REGULATION SERVICE LIMITED Room 002, Regus Harcourt Centre D02 HW77 Dublin Ireland Ireland Active (1R,2S,10R,11S,15S)-2,15-dimethyl-4-(morpholin-4-yl)-13-(pyrrolidin-1-yl)tetracyclo[8.7.0.0²,⁷.0¹¹,¹⁵]heptadecane-5,14-diol 601-595-5 119302-20-4 - View substance registered dossier
Givaudan France SAS - OR1 55, Rue de la voie des Bans CS500024 95102 Argenteuil Cedex France France Active (1R,2S,2'S,4R)-1,7,7-Trimethylbicyclo (2.2.1)heptane-2-spiro-4'-(2'-isopropyl-1',3'-dioxane) 443-460-1 - 2012 View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant UK competent national authority. - - Active (1R,2S,2'S,4R)-1,7,7-Trimethylbicyclo (2.2.1)heptane-2-spiro-4'-(2'-isopropyl-1',3'-dioxane) 443-460-1 - - View substance registered dossier
Janssen Pharmaceutica N.V. Turnhoutseweg 30 2340 Beerse Belgium Belgium Cease Manufacture (1R,2S,3S,4R)-3-((2-chloro-5-fluoropyrimidin-4-yl)amino)bicyclo[2.2.2]octane-2-carboxylic acid 821-184-6 1777721-60-4 2022 View substance registered dossier
Janssen Pharmaceutica N.V. Turnhoutseweg 30 2340 Beerse Belgium Belgium Cease Manufacture (1R,2S,3S,4R)-3-((5-fluoro-2-(5-fluoro-1-tosyl-1H-pyrrolo[2,3-b]pyridin-3-yl)pyrimidin-4-yl)amino)bicyclo[2.2.2]octane-2-carboxylic acid 821-185-1 1777721-63-7 2022 View substance registered dossier
Evonik Operations GmbH Rellinghauser Straße 1-11 45128 Essen Germany Germany Cease Manufacture (1R,2S,5R)-2-Isopropyl-5-methylcyclohexyl (2R,5R)-5-hydroxy-1,3-oxathiolane-2-carboxylate 604-569-1 147126-62-3 2021 View substance registered dossier
UNION QUIMICO FARMACÉUTICA S.A. Mallorca 262 08008 Barcelona Barcelona Spain Spain Active (1R,2S,5R)-2-Isopropyl-5-methylcyclohexyl (2R,5R)-5-hydroxy-1,3-oxathiolane-2-carboxylate 604-569-1 147126-62-3 2022 View substance registered dossier
Symrise AG Mühlenfeldstraße 1 37603 Holzminden Germany Germany Active (1R,2S,5R)-2-isopropyl-N-(4-methoxyphenyl)-5-methylcyclohexanecarboxamide 700-232-9 68489-09-8 - View substance registered dossier
Symrise AG Mühlenfeldstraße 1 37603 Holzminden Germany Germany Active (1R,2S,5R)-5-methyl-2-(propan-2-yl)cyclohexyl (ethylamino)(oxo)acetate 700-185-4 1122460-01-8 - View substance registered dossier
FINORGA - MOURENX avenue du lac 64150 MOURENX France France Active (1R,2S,5S)-6,6-dimethyl-3-[3-methyl-N-(trifluoroacetyl)-L-valyl]-3-azabicyclo[3.1.0]hexane-2-carboxylic acid 955-024-2 2755812-45-2 - View substance registered dossier
Thermofisher Scientific Cork Ltd. Currabinny P43 AY66 Carrigaline Co. Cork Ireland Ireland Active (1R,2S,5S)-6,6-dimethyl-3-[3-methyl-N-(trifluoroacetyl)-L-valyl]-3-azabicyclo[3.1.0]hexane-2-carboxylic acid 955-024-2 2755812-45-2 - View substance registered dossier
Pfizer Ireland Pharmaceuticals n/a P43 X336 Ringaskiddy Cork Ireland Ireland Active (1R,2S,5S)-6,6-dimethyl-3-[3-methyl-N-(trifluoroacetyl)-L-valyl]-3-azabicyclo[3.1.0]hexane-2-carboxylic acid 955-024-2 2755812-45-2 - View substance registered dossier
Patheon Austria GmbH & Co KG St. Peterstrasse 25 A-4020 Linz Austria Austria Active (1R,2S,5S)-6,6-dimethyl-3-[3-methyl-N-(trifluoroacetyl)-L-valyl]-3-azabicyclo[3.1.0]hexane-2-carboxylic acid 955-024-2 2755812-45-2 2022 View substance registered dossier
Pliva Hrvatska doo Prilaz baruna Filipovića 25 10000 Zagreb Croatia Croatia Active (1R,2S,6R,7S)-4-azatricyclo[5.2.1.0^{2,6}]decane-3,5-dione 689-268-3 14805-29-9 - View substance registered dossier
Pliva Hrvatska doo Prilaz baruna Filipovića 25 10000 Zagreb Croatia Croatia Active (1R,2S,6R,7S)-4-{[(1R,2R)-2-{[4-(1,2-benzothiazol-3- yl)piperazin-1-yl]methyl}-cyclohexyl]methyl}-4- azatricyclo[5.2.1.0^{2,6}]decane-3,5-dione 696-042-8 367514-87-2 - View substance registered dossier
HH Compliance Ltd Rubicon Building CIT Campus T12 Y275 Bishopstown Cork Ireland Ireland Cease Manufacture (1R,2S,8S,10S,11S,13R,14R,15S,17S)-1,8-difluoro- 14,17dihydroxy-2,13,15-trimethyl-5-oxotetracyclo[8.7.0.0^{2,7}.0^{11,15}]heptadeca-3,6-diene-14-carbothioic S-acid 617-081-9 80473-92-3 2023 View substance registered dossier
POLPHARMA 19 Pelplińska 83-200 Starogard Gdański Poland Poland Active (1R,3R)-Methyl-1,2,3,4-tetrahydro-2-chloroacetyl-1-(3,4-methylenedioxyphenyl)-9H-pyrido[3,4-b]indole-3-carboxylate 689-794-3 171489-59-1 - View substance registered dossier
[Confidential] - - - (1R,3S)-2,2-Dimethyl-3-(2-oxopropyl)cyclopropanecarboxylic acid 615-083-4 70223-33-5 - View substance registered dossier
PCAS 21 Chemin de la Sauvegarde 21 Ecully Parc - CS33167 69134 ECULLY France France Active (1R,3S)-3-aminocyclopentan-1-ol benzoate 946-279-0 1846582-38-4 - View substance registered dossier
Curia France SAS ZI de Laville 47240 BON-ENCONTRE France France Active (1R,3S)-3-aminocyclopentan-1-ol benzoate 946-279-0 1846582-38-4 - View substance registered dossier
FIRMENICH GRASSE SAS OR 1 Parc Industriel Les Bois de Grasse 06130 Grasse France France Active (1R,3S,4S,5S)-4,6,6-trimethylspiro[bicyclo[3.1.1]heptane-3,4'-cyclohex-2-ene]-1'-one 430-460-1 133636-82-5 2011; 2012 View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant UK competent national authority. - - Active (1R,3S,4S,5S)-4,6,6-trimethylspiro[bicyclo[3.1.1]heptane-3,4'-cyclohex-2-ene]-1'-one 430-460-1 133636-82-5 - View substance registered dossier
PCAS 21 Chemin de la Sauvegarde 21 Ecully Parc - CS33167 69134 ECULLY France France Active (1R,3s,5S)-8-benzyl-3-(3-isopropyl-5-methyl-4H-1,2,4-triazol-4-yl)-8-azabicyclo[3.2.1]octane 447-620-1 - 2018 View substance registered dossier
N.V. Ajinomoto OmniChem S.A. Cooppallaan 91 9230 Wetteren Oost-Vlaanderen Belgium Belgium Active (1R,3s,5S)-8-benzyl-3-(3-isopropyl-5-methyl-4H-1,2,4-triazol-4-yl)-8-azabicyclo[3.2.1]octane 447-620-1 - - View substance registered dossier
Pfizer Ireland Pharmaceuticals n/a P43 X3336 Ringaskiddy Cork Ireland Ireland Active (1R,3s,5S)-8-benzyl-3-(3-isopropyl-5-methyl-4H-1,2,4-triazol-4-yl)-8-azabicyclo[3.2.1]octane 447-620-1 - - View substance registered dossier
Bidachem S.p.A. S.S. 11 Padana Superiore No. 8 24040 Fornovo San Giovanni BG Italy Italy Active (1R,3s,5S)-8-benzyl-3-(3-isopropyl-5-methyl-4H-1,2,4-triazol-4-yl)-8-azabicyclo[3.2.1]octane 447-620-1 - - View substance registered dossier
- - - - (1R,3s,5S)-8-benzyl-3-(3-isopropyl-5-methyl-4H-1,2,4-triazol-4-yl)-8-azabicyclo[3.2.1]octane 447-620-1 - - View substance registered dossier
FINORGA SAS 497 route de Givors 38670 CHASSE SUR RHONE France France Active (1R,3s,5S)-8-benzyl-3-(3-isopropyl-5-methyl-4H-1,2,4-triazol-4-yl)-8-azabicyclo[3.2.1]octane 447-620-1 - 2010 View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant UK competent national authority. - - Active (1R,3s,5S)-8-benzyl-3-(3-isopropyl-5-methyl-4H-1,2,4-triazol-4-yl)-8-azabicyclo[3.2.1]octane 447-620-1 - - View substance registered dossier
FIRMENICH GRASSE SAS OR 1 Parc Industriel Les Bois de Grasse 06130 Grasse France France Active (1R,4aS,8R,8aS)-2,2,6,8-tetramethyl-1,2,3,4,4a,5,8,8a-octahydronaphthalen-1-ol 434-960-0 103614-86-4 2011 View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant French competent national authority. - - Active (1R,4aS,8R,8aS)-2,2,6,8-tetramethyl-1,2,3,4,4a,5,8,8a-octahydronaphthalen-1-ol 434-960-0 103614-86-4 - View substance registered dossier
[Confidential] - - - (1R,4R,5S)- 4-(1,1-Dichloro-2,2,2-trifluoroethyl)-6,6-dimethyl-3-oxabicyclo[3.1.0]hexan-2-one 606-114-2 187592-70-7 - View substance registered dossier
PCAS 21 Chemin de la Sauvegarde 21 Ecully Parc - CS33167 69134 ECULLY France France Active (1R,4S)-2-azabicyclo[2.2.1]hept-5-en-3-one 418-530-1 79200-56-9 - View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant UK competent national authority. - - Active (1R,4S)-2-azabicyclo[2.2.1]hept-5-en-3-one 418-530-1 79200-56-9 - View substance registered dossier
SONEAS Chemicals Ltd. Banyaleg Str. 47-59. H-1225 Budapest Hungary Hungary Active (1R,4S)-2-azabicyclo[2.2.1]hept-5-en-3-one 616-668-7 79200-56-9 - View substance registered dossier
Patheon Austria GmbH & Co KG St. Peterstrasse 25 A-4020 Linz Austria Austria Active (1R,4S)-6-tert-butoxy-4-(tert-butyldimethylsilyloxy)-6-oxo-1-(2-(thiophen-2-yl)acetamido)hexylboronic acid, (+)-pinanediol ester 812-137-0 1681053-97-3 - View substance registered dossier
Syngenta Ltd Jealott’s Hill International Research Centre RG42 6EY Bracknell Berkshire United Kingdom United Kingdom No longer Valid (1R,4S,4aR,8aS)-9-(dichloromethylidene)octahydro-1,4-methanonaphthalene-5,8-dione 700-729-0 - 2021 View substance registered dossier
Syngenta Hellas Single Member S.A.C.I. Anthousas Avenue 153 49 Anthousa - Attiki Greece Greece Active (1R,4S,4aR,8aS)-9-(dichloromethylidene)octahydro-1,4-methanonaphthalene-5,8-dione 700-729-0 - 2019 View substance registered dossier
[Confidential] - - - (1R,4S,4aR,8aS)-9-(dichloromethylidene)octahydro-1,4-methanonaphthalene-5,8-dione 700-729-0 - - View substance registered dossier
[Confidential] - - - (1R,4S,4aS,8aR)-9-(dichloromethylene)-1,4,4a,8a-tetrahydro-1,4-methanonaphthalene-5,8-dione 807-377-8 1263184-85-5 - View substance registered dossier
CURIA SPAIN, S.A.U. Parque Tecnológico de Boecillo, parcela 105 47151 Boecillo Valladolid Spain Spain Active (1R,5aR,10R,11aS)-1-acetyl-10-[4-(dimethylamino)phenyl]-5a-hydroxy-11a-methyl-3,3a,3b,4,5,6,8,9,10,11-decahydro-2H-spiro[cyclopenta[a]phenanthrene-7,2'-[1,3]dioxolan]-1-yl acetate 615-905-1 730962-28-4 2018 View substance registered dossier
Destilerías Muñoz Gálvez, S.A. Avda. Ciudad de Almería, 162 E30010 Murcia Murcia Spain Spain Active (1R,5R)-2,6,6-trimethylbicyclo[3.1.1]hept-2-ene 232-087-8 7785-70-8 2019 View substance registered dossier
DESTILACIONES BORDAS CHINCHURRETA, S.A. C/ Acueducto, 4-6 Pol. Ind. Ctra la Isla 41703 Dos Hermanas (Sevilla) Spain Spain Active (1R,5R)-2,6,6-trimethylbicyclo[3.1.1]hept-2-ene 232-087-8 7785-70-8 2019 View substance registered dossier
LES DERIVES RESINIQUES ET TERPENIQUES 30 rue Gambetta B.P. 206 40105 Dax Cedex France France Cease Manufacture (1R,5R)-2,6,6-trimethylbicyclo[3.1.1]hept-2-ene 232-087-8 7785-70-8 2017 View substance registered dossier
TAKASAGO TICSA-Producer/Importer Avenida de Mazarrón, 49 30120 El Palmar Murcia Spain Spain Active (1R,5S)-2-(6,6-dimethylbicyclo[3.1.1]hept-2-en-2-yl) ethyl acetate 800-940-9 35836-72-7 2020 View substance registered dossier
LES DERIVES RESINIQUES ET TERPENIQUES 30 rue Gambetta B.P. 206 40105 Dax Cedex France France Active (1R,5S)-2-(6,6-dimethylbicyclo[3.1.1]hept-2-en-2-yl) ethyl acetate 800-940-9 35836-72-7 2022 View substance registered dossier
ERNESTO VENTOS, S.A. Carretera Reial 120B 08960 Sant Just Desvern Spain Spain Active (1R,5S)-2-(6,6-dimethylbicyclo[3.1.1]hept-2-en-2-yl) ethyl acetate 800-940-9 35836-72-7 - View substance registered dossier
CU Chemie Uetikon GmbH Raiffeisenstrasse 4 77933 Lahr Baden-Württemberg Germany Germany Active (1R,5S)-8-benzyl-8-azabicyclo[3.2.1]octan-3-one hydrochloride 617-458-8 83393-23-1 - View substance registered dossier
Midas Pharma GmbH Rheinstrasse 49 55218 Ingelheim Germany Germany Active (1R,5S)-8-benzyl-8-azabicyclo[3.2.1]octan-3-one hydrochloride 617-458-8 83393-23-1 - View substance registered dossier
[Confidential] - - - (1R,5S)-8-benzyl-8-azabicyclo[3.2.1]octan-3-one hydrochloride 617-458-8 83393-23-1 - View substance registered dossier
N.V. Ajinomoto OmniChem S.A. Cooppallaan 91 9230 Wetteren Oost-Vlaanderen Belgium Belgium Cease Manufacture (1R,5S,E)-8-benzyl-8-azabicyclo[3.2.1]octan-3-one oxime 616-314-1 76272-34-9 2021 View substance registered dossier
PCAS 21 Chemin de la Sauvegarde 21 Ecully Parc - CS33167 69134 ECULLY France France Active (1R,5S,E)-8-benzyl-8-azabicyclo[3.2.1]octan-3-one oxime 616-314-1 76272-34-9 2016 View substance registered dossier
FINORGA SAS 497 route de Givors 38670 CHASSE SUR RHONE France France Active (1R,5S,E)-8-benzyl-8-azabicyclo[3.2.1]octan-3-one oxime 616-314-1 76272-34-9 - View substance registered dossier
[Confidential] - - - (1R,6S)- 4,7,7-Trimethyl-3-oxabicyclo[4.1.0]hept-4-en-2-one 615-077-1 70174-49-1 - View substance registered dossier

In this table, you will find all public data submitted to ECHA in REACH registration dossiers by substance manufacturers, importers, or their representatives, as laid out by the REACH Regulation (see Understanding REACH regulation).

ECHA makes available this information as REACH registered substance factsheets, which contain the full set of non-confidential information from related registration dossiers for a substance. Depending on the number of registrations that have been made for a substance, one factsheet can thus represent data from anything between hundreds of registration dossiers in a joint submission, to data from just one registration dossier.

As noted in the Legal Notice of the ECHA website, ECHA does not give any guarantees or warranties regarding the quality and correctness of the published information. The information in the portal is published ‘as provided’ by industry, and its accuracy has not been verified by ECHA. ECHA is also not in a position to intervene with, edit or correct the published data; this can only be done by the registrant responsible for its submission. Please also note that the information may be protected and its use may require prior permission from its owner (see the ECHA website Legal Notice more details).

In the portal results table are presented:

  • Public substance identity – the best available non-confidential substance name, EC, and CAS numbers.
  • Registration status – indicating the calculated registration status for the whole factsheet: Active – is being manufactured or imported to the EEA by one or more registrants; Cease Manufacture - is no longer being manufactured or imported above 1 tone per calendar year. All registrants of the substance have reported a cease of manufacture or import; or No longer valid - no longer considered registered under REACH and not currently allowed to be manufactured or imported to the EEA, until the substance is registered again.
  • Registration type – indicating whether a given factsheet contains data from a REACH full registration, REACH intermediate registration, or only a limited set of data inherited from a NONS notification.
  • Submission type – indicating whether the data in a given factsheet was submitted jointly or individually.
  • Total tonnage band – calculated per factsheet from all contributing registrations, based on the estimated quantity of the substance placed on the market. Data is excluded from dossiers where the tonnage is claimed confidential, from Intermediate registration dossiers, and from NONs which have not been updated.
  • Last updated – indicating the date on which this registered substance factsheet was last modified with new or updated data, based on an industry submission.
  • Link to the full factsheet.

A subset of the key chemical properties (physico-chemical, environmental fate, ecotoxicological and toxicological data) of registered substances can be searched and accessed via the OECD eChemPortal.