Registered substances

Data platform availability banner - registered substances

The new ECHA CHEM database has been released by ECHA. At first this system will contain only substances and data from REACH registration dossiers. For new and updated REACH registration data please check ECHA CHEM. See for more information on the transition to ECHA CHEM.  More

Please be aware that REACH registration data here on the current Dissemination Platform is no longer maintained; it remains frozen as of 19th May 2023.


 

DISSEMINATION
PLATFORM

REACH - Registration, Evaluation, Authorisation and Restriction of Chemicals Regulation

Registered Substances Factsheets

Substances which have been registered and can be placed on the EEA market by those companies with a valid registration



No results were found
Details
(4-6) PEPTIDE
427-550-8 - Active NONS Joint Tonnage data confidential 10-11-2008 View substance registered dossier
(4-methoxybiphenyl-3-yl)hydrazine hydrochloride
924-885-6 - Active Intermediate Joint Intermediate use only 22-10-2012 View substance registered dossier
(4-Methoxyphenyl)diphenylsulfoniumnonaflate
435-570-3 - Active NONS Joint Tonnage data confidential 24-06-2009 View substance registered dossier
(4-nitrophenyl)methyl [6R,(6α,7β)]-[3-hydroxy-5,8-dioxo-7-(phenoxyacetylamino)-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate]
ENOL SULFOXIDE ESTER
411-820-7 - Active NONS Individual Tonnage data confidential 10-11-2008 View substance registered dossier
(4-vinylphenyl)methyl-2-[(1Z)-1-aza-3-methyl-2-(4-methylthiophenyl)-3-morpholin-4-ylbut-1-enyloxy]acetate
453-050-4 - Active NONS Individual Tonnage data confidential 04-02-2011 View substance registered dossier
(4aR*, 8aR*)-1-bromo-4a,5,9,10,11,12-hexahydro-3-methoxy-6H-benzofuro[3a,3,2-ef] [2]benzazepin-6-one hydrochloride (1:1)
700-867-1 - Active Full Joint ≥ 1 to < 10 tonnes 11-06-2020 View substance registered dossier
(4aR,5S,8R,8aS)-1,2,3,4,4a,5,8,8a-octahydro-1,4:5,8-dimethanonaphthalene
700-678-4 - Active Full Individual ≥ 100 to < 1 000 tonnes 05-05-2020 View substance registered dossier
(4E)-4-(C13-C17)alkylidene-3-(C12-C16)alkyloxetan-2-one
939-401-9 - Active Full Joint ≥ 100 to < 1 000 tonnes 09-05-2023 View substance registered dossier
(4R)-4-[(3R,5S,7S,8R,9S,10S,13R,14S,17R)-3,7-dihydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]pentanoic acid;N,N-diethylethanamine
926-346-0 - Active Intermediate Joint Intermediate use only 10-11-2017 View substance registered dossier
(4R)-4-methyl-1,3-dioxolan-2-one
(R)-1,2-PROPYLENE CARBONATE
437-320-9 - Active NONS Joint Tonnage data confidential 10-11-2008 View substance registered dossier
(4R)-Tetrahydro-4-hydroxy-4-methyl-2H-Pyran-2-one
433-160-9 - Active Full Joint ≥ 1 to < 10 tonnes 18-08-2020 View substance registered dossier
(4R)-Tetrahydro-4-hydroxy-4-methyl-2H-Pyran-2-one
433-160-9 - Cease Manufacture NONS Individual Cease manufacture 10-11-2008 View substance registered dossier
(4R,4aS,7aR,12bS)-4a,9-dihydroxy-2,3,4,4a,5,6-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinolin-7(7aH)-one hemi((2R,3R)-2,3-dihydroxysuccinate)
956-466-9 - Active Intermediate Joint Intermediate use only 07-10-2022 View substance registered dossier
(4S)-3-carbamoyl-4-(4-cyano-2-methoxyphenyl)-5-ethoxy-2,8-dimethyl-1,4-dihydro-1,6-naphthyridin-1-ium (2S,3S)-2,3-bis(benzoyloxy)-3-carboxypropanoate
947-346-7 - Active Intermediate Individual Intermediate use only 03-01-2023 View substance registered dossier
(4S,4aR,5S,5aR,6R,12aS)-4-(dimethylamino)-3,5,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-1,4,4a,5,5a,6,11,12aoctahydrotetracene-2-carboxamide 4-methylbenzenesulfonate (1:1)
940-053-5 - Active Intermediate Joint Intermediate use only 19-01-2017 View substance registered dossier
(4S,4aS,5aR,12aS)-4-(dimethylamino)-3,10,12,12a-tetrahydroxy-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamide p-toluenesulfonate
947-931-7 - Active Intermediate Individual Intermediate use only 24-05-2018 View substance registered dossier
(4S,4aS,5aS,6S,12aS)-4,7-bis(dimethylamino)-3,10,12,12a-tetrahydroxy-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamide di(4-chlorobenzenesulfonic acid)
925-915-0 - Active Intermediate Individual Intermediate use only 24-05-2018 View substance registered dossier
(4S,5S)-5-hydroxy-2-methyl-3,4,5,6-tetrahydropyrimidine-4-carboxylic acid
HYDROXYECTOIN
442-870-8 - Cease Manufacture NONS Joint Cease manufacture 10-11-2008 View substance registered dossier
(4S,6S)-5,6-dihydro-4-[ethylamin-N-(2-nitrobenzenesulfonic)]-6-methyl-4H-thieno(2,3-b)thiopyran-7,7-dioxide
947-800-4 - Active Intermediate Joint Intermediate use only 21-06-2018 View substance registered dossier
(4S,7S,12bR)-7-amino-1,2,3,4,6,7,8,12b-octahydro-6-oxobenzo(c)pyrido(1,2-a)azepin-4-carbonic acid
MDL 28,690
443-440-2 - Active NONS Individual Tonnage data confidential 10-11-2008 View substance registered dossier
No results were found
Registrant/Supplier Address Country Registration Status Name EC / List no. CAS no. Last update year Details
Former NONS notifier unknown to ECHA - Contact the relevant Belgian competent national authority. - - Active (4-6) PEPTIDE 427-550-8 - - View substance registered dossier
Synthesia, a.s. Semtín103 53002 Pardubice Czech Republic Czech Republic Active (4-methoxybiphenyl-3-yl)hydrazine hydrochloride 924-885-6 - - View substance registered dossier
- - - - (4-Methoxyphenyl)diphenylsulfoniumnonaflate 435-570-3 - - View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant UK competent national authority. - - Active (4-Methoxyphenyl)diphenylsulfoniumnonaflate 435-570-3 - - View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant Irish competent national authority. - - Active (4-nitrophenyl)methyl [6R,(6α,7β)]-[3-hydroxy-5,8-dioxo-7-(phenoxyacetylamino)-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate] 411-820-7 - - View substance registered dossier
FujiFilm Manufacturing Europe BV Oudenstaart 1 5047 TK Tilburg Netherlands Netherlands Active (4-vinylphenyl)methyl-2-[(1Z)-1-aza-3-methyl-2-(4-methylthiophenyl)-3-morpholin-4-ylbut-1-enyloxy]acetate 453-050-4 - 2011 View substance registered dossier
Janssen Pharmaceutica N.V. Turnhoutseweg 30 2340 Beerse Belgium Belgium Active (4aR*, 8aR*)-1-bromo-4a,5,9,10,11,12-hexahydro-3-methoxy-6H-benzofuro[3a,3,2-ef] [2]benzazepin-6-one hydrochloride (1:1) 700-867-1 - 2020 View substance registered dossier
Labcorp Development SA 163 Parque Empresarial Las Tablas, Edificio 1 Calle Federico Mompou, 5 -5 Planta 28050 Madrid Spain Spain Active (4aR,5S,8R,8aS)-1,2,3,4,4a,5,8,8a-octahydro-1,4:5,8-dimethanonaphthalene 700-678-4 - 2019; 2020 View substance registered dossier
Solenis Netherlands B.V. Pesetastraat 62 2991 XT Barendrecht Netherlands Netherlands Active (4E)-4-(C13-C17)alkylidene-3-(C12-C16)alkyloxetan-2-one 939-401-9 - 2022; 2023 View substance registered dossier
Solenis Belgium B.V.B.A. Industrieweg 15 3583 Beringen Belgium Belgium Cease Manufacture (4E)-4-(C13-C17)alkylidene-3-(C12-C16)alkyloxetan-2-one 939-401-9 - 2016 View substance registered dossier
Mare S.p.A. Via Verdi No. 3 20002 Ossona Fraz. Asmonte Italy Italy Active (4E)-4-(C13-C17)alkylidene-3-(C12-C16)alkyloxetan-2-one 939-401-9 - 2020 View substance registered dossier
Red Orchid Consulting Oy Ltd Viherkallionkuja 3 I 59 02710 Espoo Finland Finland Active (4E)-4-(C13-C17)alkylidene-3-(C12-C16)alkyloxetan-2-one 939-401-9 - 2022 View substance registered dossier
DIPHARMA FRANCIS srl Bissone, 5 20021 Baranzate Milano Italy Italy Active (4R)-4-[(3R,5S,7S,8R,9S,10S,13R,14S,17R)-3,7-dihydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]pentanoic acid;N,N-diethylethanamine 926-346-0 - - View substance registered dossier
Sterling Pharma Solutions Ltd Dudley NE23 7QG Cramlington Northumberland United Kingdom United Kingdom No longer Valid (4R)-4-methyl-1,3-dioxolan-2-one 437-320-9 - 2021 View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant UK competent national authority. - - Active (4R)-4-methyl-1,3-dioxolan-2-one 437-320-9 - - View substance registered dossier
Visolis, B.V. Urmonderbaan 22 6167 RD Geleen Netherlands Netherlands Active (4R)-Tetrahydro-4-hydroxy-4-methyl-2H-Pyran-2-one 433-160-9 - - View substance registered dossier
- - - - (4R)-Tetrahydro-4-hydroxy-4-methyl-2H-Pyran-2-one 433-160-9 - - View substance registered dossier
Cambrex Karlskoga AB Bjorkborns Industriomrade 69185 Karlskoga Sweden Sweden Active (4R,4aS,7aR,12bS)-4a,9-dihydroxy-2,3,4,4a,5,6-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinolin-7(7aH)-one hemi((2R,3R)-2,3-dihydroxysuccinate) 956-466-9 - - View substance registered dossier
Bayer AG Kaiser-Wilhelm-Allee 1 51373 Leverkusen Germany Germany Active (4S)-3-carbamoyl-4-(4-cyano-2-methoxyphenyl)-5-ethoxy-2,8-dimethyl-1,4-dihydro-1,6-naphthyridin-1-ium (2S,3S)-2,3-bis(benzoyloxy)-3-carboxypropanoate 947-346-7 - 2020; 2021; 2023 View substance registered dossier
Hovione FarmaCiencia SA Sete Casas 2674-506 Loures Portugal Portugal Active (4S,4aR,5S,5aR,6R,12aS)-4-(dimethylamino)-3,5,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-1,4,4a,5,5a,6,11,12aoctahydrotetracene-2-carboxamide 4-methylbenzenesulfonate (1:1) 940-053-5 - 2017 View substance registered dossier
Hovione Limited Loughbeg not available Ringaskiddy County Cork Ireland Ireland Active (4S,4aR,5S,5aR,6R,12aS)-4-(dimethylamino)-3,5,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-1,4,4a,5,5a,6,11,12aoctahydrotetracene-2-carboxamide 4-methylbenzenesulfonate (1:1) 940-053-5 - 2017 View substance registered dossier
Cipan - Companhia Industrial Produtora de Antibióticos Rua da Estação, 42 Vala do Carregado 2600-726 Castanheira do Ribatejo Lisboa Portugal Portugal Active (4S,4aS,5aR,12aS)-4-(dimethylamino)-3,10,12,12a-tetrahydroxy-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamide p-toluenesulfonate 947-931-7 - - View substance registered dossier
Cipan - Companhia Industrial Produtora de Antibióticos Rua da Estação, 42 Vala do Carregado 2600-726 Castanheira do Ribatejo Lisboa Portugal Portugal Active (4S,4aS,5aS,6S,12aS)-4,7-bis(dimethylamino)-3,10,12,12a-tetrahydroxy-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamide di(4-chlorobenzenesulfonic acid) 925-915-0 - - View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant German competent national authority. - - No longer Valid (4S,5S)-5-hydroxy-2-methyl-3,4,5,6-tetrahydropyrimidine-4-carboxylic acid 442-870-8 - 2022 View substance registered dossier
- - - - (4S,5S)-5-hydroxy-2-methyl-3,4,5,6-tetrahydropyrimidine-4-carboxylic acid 442-870-8 - - View substance registered dossier
DUKE CHEM, S.A. Avgda. Mare de Déu de Montserrat, 93 - 99 Pol. Ind. Sant Pere Molanta 08799 Olèrdola Barcelona Spain Spain Active (4S,6S)-5,6-dihydro-4-[ethylamin-N-(2-nitrobenzenesulfonic)]-6-methyl-4H-thieno(2,3-b)thiopyran-7,7-dioxide 947-800-4 - - View substance registered dossier
Sanofi S.R.L. Viale Luigi Bodio n. 37/b 20158 Milano Italy Italy Active (4S,7S,12bR)-7-amino-1,2,3,4,6,7,8,12b-octahydro-6-oxobenzo(c)pyrido(1,2-a)azepin-4-carbonic acid 443-440-2 - - View substance registered dossier

In this table, you will find all public data submitted to ECHA in REACH registration dossiers by substance manufacturers, importers, or their representatives, as laid out by the REACH Regulation (see Understanding REACH regulation).

ECHA makes available this information as REACH registered substance factsheets, which contain the full set of non-confidential information from related registration dossiers for a substance. Depending on the number of registrations that have been made for a substance, one factsheet can thus represent data from anything between hundreds of registration dossiers in a joint submission, to data from just one registration dossier.

As noted in the Legal Notice of the ECHA website, ECHA does not give any guarantees or warranties regarding the quality and correctness of the published information. The information in the portal is published ‘as provided’ by industry, and its accuracy has not been verified by ECHA. ECHA is also not in a position to intervene with, edit or correct the published data; this can only be done by the registrant responsible for its submission. Please also note that the information may be protected and its use may require prior permission from its owner (see the ECHA website Legal Notice more details).

In the portal results table are presented:

  • Public substance identity – the best available non-confidential substance name, EC, and CAS numbers.
  • Registration status – indicating the calculated registration status for the whole factsheet: Active – is being manufactured or imported to the EEA by one or more registrants; Cease Manufacture - is no longer being manufactured or imported above 1 tone per calendar year. All registrants of the substance have reported a cease of manufacture or import; or No longer valid - no longer considered registered under REACH and not currently allowed to be manufactured or imported to the EEA, until the substance is registered again.
  • Registration type – indicating whether a given factsheet contains data from a REACH full registration, REACH intermediate registration, or only a limited set of data inherited from a NONS notification.
  • Submission type – indicating whether the data in a given factsheet was submitted jointly or individually.
  • Total tonnage band – calculated per factsheet from all contributing registrations, based on the estimated quantity of the substance placed on the market. Data is excluded from dossiers where the tonnage is claimed confidential, from Intermediate registration dossiers, and from NONs which have not been updated.
  • Last updated – indicating the date on which this registered substance factsheet was last modified with new or updated data, based on an industry submission.
  • Link to the full factsheet.

A subset of the key chemical properties (physico-chemical, environmental fate, ecotoxicological and toxicological data) of registered substances can be searched and accessed via the OECD eChemPortal.