Registered substances

Data platform availability banner - registered substances

New Data Availability System

A new Data Availability System is being developed by ECHA. To begin with this system will take over the responsibility of making REACH registration data available, once it is ready. We expect the first version to be publicly available by the end of 2023.

Since ECHA aims to devote our maximum effort to this new system, we can no longer maintain REACH registration data on the current Dissemination Platform. As such once the IUCLID format change begins on 19th May 2023 we will no longer update REACH registered substance factsheets. The factsheets will remain online, but will not be updated.

New and updated REACH registration submissions, as well as all registrations on file, will be made available in the new system when it is ready. We will inform you of what you can expect in the new system, along with details of when and where to find it.

We appreciate your understanding in the meantime.

DISSEMINATION
PLATFORM

REACH - Registration, Evaluation, Authorisation and Restriction of Chemicals Regulation

Registered Substances Factsheets

Substances which have been registered and can be placed on the EEA market by those companies with a valid registration



No results were found
Details
4,4’-isopropylidenediphenol, reaction products with 1-chloro-2,3-epoxypropane, mono, di and triesters with acrylic acid
948-054-2 - Active Full Joint ≥ 0 to < 10 tonnes 13-01-2023 View substance registered dossier
4,5-di-tert-butyl-6-ethoxy-2,2-dimethyl-3,7-dioxa-4-aza-6-phosphanonan-1-oic acid 6-oxide
449-920-8 - Active NONS Individual Tonnage data confidential 16-12-2010 View substance registered dossier
4,5-Dihydro-5-methyl-3,4-diphenyl-5-isoxazolol
443-400-4 - Active Intermediate Joint Intermediate use only 20-08-2018 View substance registered dossier
4,5-Dihydro-5-methyl-3,4-diphenyl-5-isoxazolol
443-400-4 - Active NONS Individual Tonnage data confidential 10-11-2008 View substance registered dossier
4,5-dihydro-5-oxo-1-(4-sulfophenyl)-4-(4-{2-[1,2,7,8-tetrahydro-7-(4-nitro-2-sulfophenylhydrazono)-1,8-dioxo-3,6-disulfo-2-naphthylidene]hydrazino}-3-sulfophenylhydrazono)pyrazole-3-carboxylic acid, lithium sodium salt
445-080-1 - No longer Valid NONS Individual No longer valid 24-11-2010 View substance registered dossier
4,5-dihydro-5-oxo-1-(4-sulfophenyl)-4-(4-{2-[1,2,7,8-tetrahydro-7-(4-nitro-2-sulfophenylhydrazono)-1,8-dioxo-3,6-disulfo-2-naphthylidene]hydrazino}-3-sulfophenylhydrazono)pyrazole-3-carboxylic acid, lithium sodium salt
445-080-1 - Active NONS Individual Tonnage data confidential 29-04-2021 View substance registered dossier
4,6-Dichloro-5-fluoropyrimidine
446-560-3 - Active Intermediate Joint Intermediate use only 30-06-2022 View substance registered dossier
4,7-methanooctahydro-1H-indene-diyldimethyl bis(2-carboxybenzoate)
TCD EMULGATOR
407-410-2 - Active Full Individual ≥ 100 to < 1 000 tonnes 08-12-2016 View substance registered dossier
4,7-methanooctahydro-1H-indene-diyldimethyl bis(2-carboxybenzoate)
TCD EMULGATOR
407-410-2 - Active NONS Joint Tonnage data confidential 09-11-2011 View substance registered dossier
4-(1-((3-((2-(tert-butoxycarbonyl(methyl)amino)acetoxy)methyl)pyridin-2-yl)(methyl)carbamoyloxy)ethyl)-1-((2R,3S)-3-(4-(4-cyanophenyl)thiazol-2-yl)-2-(2,5-difluorophenyl)-2-hydroxybutyl)-1H-1,2,4-triazol-4-ium sulphate
926-418-1 - Active Intermediate Individual Intermediate use only 09-05-2018 View substance registered dossier
4-(2-aminoethyl)indole, fumarate
947-445-5 - Active Intermediate Joint Intermediate use only 07-05-2018 View substance registered dossier
4-(2-carboxymethylthio)ethoxy-1-hydroxy-5-isobutyloxycarbonylamino-N-(3-dodecyloxypropyl)-2-naphthamide
UC-135
420-730-7 - Cease Manufacture NONS Individual Cease manufacture 10-11-2008 View substance registered dossier
4-(2-Hydroxyethyl)indolin-2-one
925-636-4 - Active Intermediate Individual Intermediate use only 08-03-2021 View substance registered dossier
4-(3,4-dichlorophenyl)tetralin-1-one
406-300-1 - Active Intermediate Joint Intermediate use only 25-07-2021 View substance registered dossier
4-(3,4-dichlorophenyl)tetralin-1-one
406-300-1 - Active Intermediate Joint Intermediate use only 15-02-2018 View substance registered dossier
4-(3,4-dichlorophenyl)tetralin-1-one
406-300-1 - Active NONS Joint Tonnage data confidential 20-08-2010 View substance registered dossier
4-(4'-Trifluoromethylphenyl)benzaldehyde
473-430-3 - Cease Manufacture NONS Individual Cease manufacture 10-11-2008 View substance registered dossier
4-(4-(4-(hydroxydiphenylmethyl)-1-piperidinyl)-1-butynyl)-α,α-dimethylbenzeneacetic acid
462-560-6 - No longer Valid Intermediate Individual No longer valid 10-05-2011 View substance registered dossier
4-(4-(4-(hydroxydiphenylmethyl)-1-piperidinyl)-1-butynyl)-α,α-dimethylbenzeneacetic acid
462-560-6 - Active Intermediate Joint Intermediate use only 06-07-2015 View substance registered dossier
4-(4-Brom-5-ethyl-tetrahydropyran-2-yl)-phenol
919-822-4 - Active Intermediate Joint Intermediate use only 25-05-2018 View substance registered dossier
4-(4-Brom-5-propyl-tetrahydropyran-2-yl)-phenol
917-991-9 - Active Intermediate Joint Intermediate use only 16-02-2018 View substance registered dossier
4-(4-chloro-3-nitro-phenyl)-3-methyl-4-oxo-butanoic acid
918-019-6 - Active Intermediate Joint Intermediate use only 31-05-2018 View substance registered dossier
4-(4-chlorophenyl)-1-imidazol-1-ylbutan-2-ol
925-590-5 - Active Intermediate Joint Intermediate use only 16-01-2017 View substance registered dossier
4-(4-cyano-2-methoxyphenyl)-5-ethoxy-2,8-dimethyl-1,4-dihydro-1,6-naphthyridine-3-carboxamide
810-201-2 - Active Intermediate Individual Intermediate use only 22-02-2023 View substance registered dossier
4-(4-cyano-2-methoxyphenyl)-5-ethoxy-2,8-dimethyl-1,4-dihydro-1,6-naphthyridine-3-carboxylic acid
810-200-7 - Active Intermediate Individual Intermediate use only 22-02-2023 View substance registered dossier
4-(4-hydroxyphenyl)cyclohexanone
4-(4'-HYDROXYPHENYL)-CYCLOHEXANON
423-920-8 - Cease Manufacture NONS Individual Cease manufacture 10-11-2008 View substance registered dossier
4-(4-trans-propylcylohexyl)phenol
PCH-3-PHENOL
440-740-5 - Active Intermediate Joint Intermediate use only 20-12-2019 View substance registered dossier
4-(4-trans-vinyl-[1,1'-bicyclohexyl]-4'-trans-yl)-1,2-difluorobenzene
430-860-6 - Active NONS Individual Tonnage data confidential 05-11-2019 View substance registered dossier
4-(5-(3,5-dichloro-4-fluorophenyl)-5-(trifluoromethyl)-4,5-dihydro-1,2-oxazol-3-yl)-N-(2-ethyl-3-oxo-1,2-oxazolidin-4-yl)-2-methylbenzamide
954-921-6 - Active Full Joint ≥ 0 to < 10 tonnes 04-04-2023 View substance registered dossier
4-(5-(5-[1-(4-carboxyphenyl)hexahydro-2,4,6-trioxopyrimidin-5-ylidene]penta-1,3-dienyl)-1,2,3,4-tetrahydro-6-hydroxy-2,4-dioxopyrimidin-1-yl)benzoic acid-triethylamine salt
426-900-7 - Active NONS Joint Tonnage data confidential 10-11-2008 View substance registered dossier
4-(5-ethoxyheptyl)perhydropentalen-2-one
ETHOCYN
419-880-6 - No longer Valid NONS Individual No longer valid 10-11-2008 View substance registered dossier
4-(5-Ethyl-tetrahydropyran-2-yl)-phenol
921-114-5 - Active Full Joint ≥ 0 to < 10 tonnes 23-10-2020 View substance registered dossier
4-(5-methyl-3-phenylisoxazol-4-yl)benzenesulfonamide
VALDECOXIB
448-010-8 - Active NONS Individual Tonnage data confidential 15-12-2008 View substance registered dossier
4-(5-methyl-3-phenylisoxazol-4-yl)benzenesulfonamide
VALDECOXIB
448-010-8 - Active Intermediate Joint Intermediate use only 20-08-2018 View substance registered dossier
4-(5-Propyl-tetrahydropyran-2-yl)-phenol
919-949-5 - Active Full Joint ≥ 0 to < 10 tonnes 17-12-2021 View substance registered dossier
4-(6-(3,6-diazabicyclo[3.1.1]heptan-3-yl)pyridin-3-yl)-6-(2-hydroxy-2-methylpropoxy)pyrazolo[1,5-a]pyridine-3-carbonitrile bis sulphate
951-814-6 - Active Intermediate Individual Intermediate use only 03-01-2020 View substance registered dossier
4-(6-acryloyloxyhexyloxy)benzoic acid (4-(trans-4-propylcyclohexyl)phenyl ester)
425-880-7 - Active Full Joint ≥ 1 to < 10 tonnes 21-05-2019 View substance registered dossier
4-(6-acryloyloxyhexyloxy)benzoic acid (4-(trans-4-propylcyclohexyl)phenyl ester)
425-880-7 - No longer Valid NONS Individual No longer valid 10-11-2008 View substance registered dossier
4-(Difluoro-(3,4,5-trifluoro-phenoxy)-methyl)-3,5-difluoro-benzaldehyde
942-738-4 - Active Full Joint ≥ 0 to < 10 tonnes 18-10-2022 View substance registered dossier
4-(nitromethyl)-1-(2-phenylethyl)piperidin-4-ol;hydrochloride
928-867-9 - Active Intermediate Joint Intermediate use only 14-02-2017 View substance registered dossier
4-(trans-4-Propylcyclohexyl)-1-bromobenzene
485-340-1 - Active Intermediate Joint Intermediate use only 19-11-2019 View substance registered dossier
4-(trans-4-propylcyclohexyl)phenyl acetic acid
PCH-3-ESSIGSÄURE
435-100-7 - No longer Valid NONS Individual No longer valid 10-11-2008 View substance registered dossier
4-({6-AMINO-2-[(4-CYANOPHENYL)AMINO]PYRIMIDIN-4-YL}OXY)-3,5-DIMETHYLBENZONITRILE
458-850-7 - Active NONS Joint Tonnage data confidential 23-05-2018 View substance registered dossier
4-[(2-{[3,5-bis(trifluoromethyl)benzyl][(2R,4S)-1-(ethoxycarbonyl)-2-ethyl-6-(trifluoromethyl)-1,2,3,4-tetrahydroquinolin-4-yl]amino}pyrimidin-5-yl)oxy]butanoic acid
- - Active Intermediate Joint Intermediate use only 19-04-2023 View substance registered dossier
4-[(3-isobutoxy-1-isobutoxycarbonyl-3-oxopropyl)(3-octyloxypropyl)amino]-4-oxobutyric acid;reaction mass of: 4-[(3-decyloxypropyl)(3-isobutoxy-1-isobutoxycarbonyl-3-oxopropyl)amino]-4-oxobutyric acid
423-750-4 - Active NONS Individual Tonnage data confidential 11-04-2012 View substance registered dossier
4-[(4,6-bis{[3-(diethylamino)propyl]amino}-heteromonocycle-2-yl)amino]-N-[2-(4,5,6,7-tetrachloro-1,3-dioxo-2,3-dihydro-1H-inden-2-yl)quinolin-8-yl]benzenesulfonamide
- - Active Full Individual ≥ 1 to < 10 tonnes 05-10-2011 View substance registered dossier
4-[(4-(aminoiminomethyl)phenyl)amino]-4-oxobutanoic acid hydrochloride
ABAS
430-340-9 - Active NONS Individual Tonnage data confidential 10-11-2008 View substance registered dossier
4-[(4-chloro-6-{[(3 or 4)-sulfophenyl]amino}-1,3,5-triazin-2-yl)amino]-2-{[1-ethyl-2-hydroxy-4-methyl-6-oxo-5-(sulfonatomethyl)-1,6-dihydropyridin-3-yl]diazenyl}benzenesulfonic acid, lithium sodium salts
- - Active Full Individual ≥ 10 to < 100 tonnes 01-10-2019 View substance registered dossier
4-[(4-Fluorophenylimino)methyl]phenol
438-950-7 - Active NONS Joint Tonnage data confidential 10-11-2008 View substance registered dossier
4-[(4-Fluorophenylimino)methyl]phenol
438-950-7 - Active Intermediate Joint Intermediate use only 25-07-2019 View substance registered dossier
No results were found
Registrant/Supplier Address Country Registration Status Name EC / List no. CAS no. Last update year Details
Yordas GmbH Äußere Nürnberger Str. 62, 91301 Forchheim Germany Germany Active 4,4’-isopropylidenediphenol, reaction products with 1-chloro-2,3-epoxypropane, mono, di and triesters with acrylic acid 948-054-2 - 2019; 2023 View substance registered dossier
ARKEMA FRANCE 420 rue d'Estienne d'Orves 92700 COLOMBES France France Active 4,5-di-tert-butyl-6-ethoxy-2,2-dimethyl-3,7-dioxa-4-aza-6-phosphanonan-1-oic acid 6-oxide 449-920-8 - 2010 View substance registered dossier
Pfizer Ireland Pharmaceuticals n/a P43 X336 Ringaskiddy Cork Ireland Ireland Active 4,5-Dihydro-5-methyl-3,4-diphenyl-5-isoxazolol 443-400-4 - 2016 View substance registered dossier
Piramal Healthcare UK Ltd Whalton Road NE61 3YA Morpeth Northumberland United Kingdom United Kingdom No longer Valid 4,5-Dihydro-5-methyl-3,4-diphenyl-5-isoxazolol 443-400-4 - 2021 View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant UK competent national authority. - - Active 4,5-Dihydro-5-methyl-3,4-diphenyl-5-isoxazolol 443-400-4 - - View substance registered dossier
Fujifilm Imaging Colorants Limited Patricia Way Pysons Road Industrial Estate CT10 2LE Broadstairs Kent United Kingdom United Kingdom No longer Valid 4,5-dihydro-5-oxo-1-(4-sulfophenyl)-4-(4-{2-[1,2,7,8-tetrahydro-7-(4-nitro-2-sulfophenylhydrazono)-1,8-dioxo-3,6-disulfo-2-naphthylidene]hydrazino}-3-sulfophenylhydrazono)pyrazole-3-carboxylic acid, lithium sodium salt 445-080-1 - 2021 View substance registered dossier
Fujifilm Europe GmbH (OR1) Balcke-Dürr-Allee 6 40882 Ratingen Germany Germany Active 4,5-dihydro-5-oxo-1-(4-sulfophenyl)-4-(4-{2-[1,2,7,8-tetrahydro-7-(4-nitro-2-sulfophenylhydrazono)-1,8-dioxo-3,6-disulfo-2-naphthylidene]hydrazino}-3-sulfophenylhydrazono)pyrazole-3-carboxylic acid, lithium sodium salt 445-080-1 - 2021 View substance registered dossier
Bayer AG Kaiser-Wilhelm-Allee 1 51373 Leverkusen Germany Germany Active 4,6-Dichloro-5-fluoropyrimidine 446-560-3 - 2010; 2022 View substance registered dossier
ELIX Polymers, S.L. Poligono Industrial s/n Ctra. de Vilaseca - La Pineda 43006 Tarragona Spain Spain Active 4,7-methanooctahydro-1H-indene-diyldimethyl bis(2-carboxybenzoate) 407-410-2 - 2016 View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant German competent national authority. - - Active 4,7-methanooctahydro-1H-indene-diyldimethyl bis(2-carboxybenzoate) 407-410-2 - - View substance registered dossier
INEOS Styrolution Köln GmbH Alte Str. 201 50769 Köln NRW Germany Germany Active 4,7-methanooctahydro-1H-indene-diyldimethyl bis(2-carboxybenzoate) 407-410-2 - 2011 View substance registered dossier
[Confidential] - - - 4-(1-((3-((2-(tert-butoxycarbonyl(methyl)amino)acetoxy)methyl)pyridin-2-yl)(methyl)carbamoyloxy)ethyl)-1-((2R,3S)-3-(4-(4-cyanophenyl)thiazol-2-yl)-2-(2,5-difluorophenyl)-2-hydroxybutyl)-1H-1,2,4-triazol-4-ium sulphate 926-418-1 - - View substance registered dossier
URQUIMA S.A. AVDA. CAMÍ REIAL, 51 -57 08184 PALAU-SOLITÀ I PLEGAMANS CATALUNYA Spain Spain Active 4-(2-aminoethyl)indole, fumarate 947-445-5 - - View substance registered dossier
FujiFilm Manufacturing Europe BV Oudenstaart 1 5047 TK Tilburg Netherlands Netherlands Cease Manufacture 4-(2-carboxymethylthio)ethoxy-1-hydroxy-5-isobutyloxycarbonylamino-N-(3-dodecyloxypropyl)-2-naphthamide 420-730-7 - 2019 View substance registered dossier
Thermofisher Scientific Cork Ltd. Currabinny P43 AY66 Carrigaline Co. Cork Ireland Ireland Active 4-(2-Hydroxyethyl)indolin-2-one 925-636-4 - 2021 View substance registered dossier
Alkaloida Chemical Company Zrt. Kabay Janos 29 H-4440 Tiszavasvari Hungary Hungary Active 4-(3,4-dichlorophenyl)tetralin-1-one 406-300-1 - - View substance registered dossier
Aceto France SAS 3 Rue de Genève CS 50363 BP 50367 Lyon Cedex 06 France France Active 4-(3,4-dichlorophenyl)tetralin-1-one 406-300-1 - 2017 View substance registered dossier
MOEHS CATALANA Cesar Martinell i Brunet 12 A 08191 Rubi Barcelona Spain Spain Active 4-(3,4-dichlorophenyl)tetralin-1-one 406-300-1 - - View substance registered dossier
MOEHS BCN, S.L. C/ Zenc, 12 08755 Castellbisbal Barcelona Spain Spain Active 4-(3,4-dichlorophenyl)tetralin-1-one 406-300-1 - - View substance registered dossier
FINORGA SAS 497 route de Givors 38670 CHASSE SUR RHONE France France Active 4-(3,4-dichlorophenyl)tetralin-1-one 406-300-1 - 2010 View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant Italian competent national authority. - - Active 4-(3,4-dichlorophenyl)tetralin-1-one 406-300-1 - - View substance registered dossier
- - - - 4-(4'-Trifluoromethylphenyl)benzaldehyde 473-430-3 - - View substance registered dossier
Fine and Performance Chemicals Ltd Skutterskelfe TS15 0JR Hutton Rudby North Yorkshire United Kingdom United Kingdom No longer Valid 4-(4-(4-(hydroxydiphenylmethyl)-1-piperidinyl)-1-butynyl)-α,α-dimethylbenzeneacetic acid 462-560-6 - 2021 View substance registered dossier
DIPHARMA FRANCIS srl Bissone, 5 20021 Baranzate Milano Italy Italy Active 4-(4-(4-(hydroxydiphenylmethyl)-1-piperidinyl)-1-butynyl)-α,α-dimethylbenzeneacetic acid 462-560-6 - 2013; 2015 View substance registered dossier
Amino Chemicals Ltd Industrial Estate, A61 MRS3000 Marsa Malta Malta Active 4-(4-(4-(hydroxydiphenylmethyl)-1-piperidinyl)-1-butynyl)-α,α-dimethylbenzeneacetic acid 462-560-6 - - View substance registered dossier
Merck KGaA Frankfurter Strasse 250 64293 Darmstadt Germany Germany Active 4-(4-Brom-5-ethyl-tetrahydropyran-2-yl)-phenol 919-822-4 - - View substance registered dossier
Merck KGaA Frankfurter Strasse 250 64293 Darmstadt Germany Germany Active 4-(4-Brom-5-propyl-tetrahydropyran-2-yl)-phenol 917-991-9 - - View substance registered dossier
All'Chem rue Marceau 03108 MONTLUCON CEDEX France France Active 4-(4-chloro-3-nitro-phenyl)-3-methyl-4-oxo-butanoic acid 918-019-6 - - View substance registered dossier
Derivados Químicos S.A. Camino de Pliego, 150 30820 Alcantarilla Murcia Spain Spain Active 4-(4-chlorophenyl)-1-imidazol-1-ylbutan-2-ol 925-590-5 - - View substance registered dossier
Bayer AG Kaiser-Wilhelm-Allee 1 51373 Leverkusen Germany Germany Active 4-(4-cyano-2-methoxyphenyl)-5-ethoxy-2,8-dimethyl-1,4-dihydro-1,6-naphthyridine-3-carboxamide 810-201-2 - 2018; 2023 View substance registered dossier
Bayer AG Kaiser-Wilhelm-Allee 1 51373 Leverkusen Germany Germany Active 4-(4-cyano-2-methoxyphenyl)-5-ethoxy-2,8-dimethyl-1,4-dihydro-1,6-naphthyridine-3-carboxylic acid 810-200-7 - 2018; 2023 View substance registered dossier
- - - - 4-(4-hydroxyphenyl)cyclohexanone 423-920-8 - - View substance registered dossier
Merck KGaA Frankfurter Strasse 250 64293 Darmstadt Germany Germany Active 4-(4-trans-propylcylohexyl)phenol 440-740-5 - 2009; 2010; 2013; 2017; 2019 View substance registered dossier
Merck KGaA Frankfurter Strasse 250 64293 Darmstadt Germany Germany Active 4-(4-trans-vinyl-[1,1'-bicyclohexyl]-4'-trans-yl)-1,2-difluorobenzene 430-860-6 - 2019 View substance registered dossier
Syngenta Hellas Single Member S.A.C.I. Anthousas Avenue 153 49 Anthousa-Attiki Greece Greece Active 4-(5-(3,5-dichloro-4-fluorophenyl)-5-(trifluoromethyl)-4,5-dihydro-1,2-oxazol-3-yl)-N-(2-ethyl-3-oxo-1,2-oxazolidin-4-yl)-2-methylbenzamide 954-921-6 - 2023 View substance registered dossier
Syngenta Hellas Single Member S.A.C.I. Anthousas Avenue 153 49 Anthousa-Attiki Greece Greece Active 4-(5-(3,5-dichloro-4-fluorophenyl)-5-(trifluoromethyl)-4,5-dihydro-1,2-oxazol-3-yl)-N-(2-ethyl-3-oxo-1,2-oxazolidin-4-yl)-2-methylbenzamide 954-921-6 - 2021 View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant French competent national authority. - - Active 4-(5-(5-[1-(4-carboxyphenyl)hexahydro-2,4,6-trioxopyrimidin-5-ylidene]penta-1,3-dienyl)-1,2,3,4-tetrahydro-6-hydroxy-2,4-dioxopyrimidin-1-yl)benzoic acid-triethylamine salt 426-900-7 - - View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant German competent national authority. - - No longer Valid 4-(5-ethoxyheptyl)perhydropentalen-2-one 419-880-6 - 2022 View substance registered dossier
Merck KGaA Frankfurter Strasse 250 64293 Darmstadt Germany Germany Active 4-(5-Ethyl-tetrahydropyran-2-yl)-phenol 921-114-5 - 2020 View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant Irish competent national authority. - - Active 4-(5-methyl-3-phenylisoxazol-4-yl)benzenesulfonamide 448-010-8 - - View substance registered dossier
Piramal Healthcare UK Ltd Whalton Road NE61 3YA Morpeth Northumberland United Kingdom United Kingdom No longer Valid 4-(5-methyl-3-phenylisoxazol-4-yl)benzenesulfonamide 448-010-8 - 2021 View substance registered dossier
Pfizer Ireland Pharmaceuticals n/a P43 X336 Ringaskiddy Cork Ireland Ireland Active 4-(5-methyl-3-phenylisoxazol-4-yl)benzenesulfonamide 448-010-8 - 2016 View substance registered dossier
Merck KGaA Frankfurter Strasse 250 64293 Darmstadt Germany Germany Active 4-(5-Propyl-tetrahydropyran-2-yl)-phenol 919-949-5 - 2021 View substance registered dossier
Eli Lilly Kinsale Limited Dunderrow Kinsale P17 NY71 Cork Co. Cork Ireland Ireland Active 4-(6-(3,6-diazabicyclo[3.1.1]heptan-3-yl)pyridin-3-yl)-6-(2-hydroxy-2-methylpropoxy)pyrazolo[1,5-a]pyridine-3-carbonitrile bis sulphate 951-814-6 - - View substance registered dossier
Merck KGaA Frankfurter Strasse 250 64293 Darmstadt Germany Germany Active 4-(6-acryloyloxyhexyloxy)benzoic acid (4-(trans-4-propylcyclohexyl)phenyl ester) 425-880-7 - - View substance registered dossier
ORGAPHARM Rue du Moulin de la Canne 45300 PITHIVIERS France France Active 4-(6-acryloyloxyhexyloxy)benzoic acid (4-(trans-4-propylcyclohexyl)phenyl ester) 425-880-7 - 2019 View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant UK competent national authority. - - No longer Valid 4-(6-acryloyloxyhexyloxy)benzoic acid (4-(trans-4-propylcyclohexyl)phenyl ester) 425-880-7 - 2022 View substance registered dossier
Merck KGaA Frankfurter Strasse 250 64293 Darmstadt Germany Germany Active 4-(Difluoro-(3,4,5-trifluoro-phenoxy)-methyl)-3,5-difluoro-benzaldehyde 942-738-4 - 2018; 2022 View substance registered dossier
ERREGIERRE SPA Via Francesco Baracca, 19 24060 SAN PAOLO D'ARGON BERGAMO Italy Italy Active 4-(nitromethyl)-1-(2-phenylethyl)piperidin-4-ol;hydrochloride 928-867-9 - - View substance registered dossier
Merck KGaA Frankfurter Strasse 250 64293 Darmstadt Germany Germany Active 4-(trans-4-Propylcyclohexyl)-1-bromobenzene 485-340-1 - 2018; 2019 View substance registered dossier
ORGAPHARM Rue du Moulin de la Canne 45300 PITHIVIERS France France Active 4-(trans-4-Propylcyclohexyl)-1-bromobenzene 485-340-1 - - View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant German competent national authority. - - No longer Valid 4-(trans-4-propylcyclohexyl)phenyl acetic acid 435-100-7 - 2022 View substance registered dossier
Janssen Pharmaceutical Science Unlimited Company Little Island County NA Cork Ireland Ireland Active 4-({6-AMINO-2-[(4-CYANOPHENYL)AMINO]PYRIMIDIN-4-YL}OXY)-3,5-DIMETHYLBENZONITRILE 458-850-7 - 2018 View substance registered dossier
Patheon Austria GmbH & Co KG St. Peterstrasse 25 A-4020 Linz Austria Austria Active 4-[(2-{[3,5-bis(trifluoromethyl)benzyl][(2R,4S)-1-(ethoxycarbonyl)-2-ethyl-6-(trifluoromethyl)-1,2,3,4-tetrahydroquinolin-4-yl]amino}pyrimidin-5-yl)oxy]butanoic acid - - 2023 View substance registered dossier
King Industries International Science Park 402 1098 XH Amsterdam Amsterdam Netherlands Netherlands Active 4-[(3-isobutoxy-1-isobutoxycarbonyl-3-oxopropyl)(3-octyloxypropyl)amino]-4-oxobutyric acid;reaction mass of: 4-[(3-decyloxypropyl)(3-isobutoxy-1-isobutoxycarbonyl-3-oxopropyl)amino]-4-oxobutyric acid 423-750-4 - 2012 View substance registered dossier
TOYO INK EUROPE SPECIALTY CHEMICALS Boulevard Dambourney 76350 Oissel France France Active 4-[(4,6-bis{[3-(diethylamino)propyl]amino}-heteromonocycle-2-yl)amino]-N-[2-(4,5,6,7-tetrachloro-1,3-dioxo-2,3-dihydro-1H-inden-2-yl)quinolin-8-yl]benzenesulfonamide - - - View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant UK competent national authority. - - Active 4-[(4-(aminoiminomethyl)phenyl)amino]-4-oxobutanoic acid hydrochloride 430-340-9 - - View substance registered dossier
Only representative (No publishable name) - - Active 4-[(4-chloro-6-{[(3 or 4)-sulfophenyl]amino}-1,3,5-triazin-2-yl)amino]-2-{[1-ethyl-2-hydroxy-4-methyl-6-oxo-5-(sulfonatomethyl)-1,6-dihydropyridin-3-yl]diazenyl}benzenesulfonic acid, lithium sodium salts - - 2017; 2019 View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant Irish competent national authority. - - Active 4-[(4-Fluorophenylimino)methyl]phenol 438-950-7 - - View substance registered dossier
Krka, d. d., Novo mesto Smarjeska cesta 6 SI-8501 Novo mesto Slovenia Slovenia Active 4-[(4-Fluorophenylimino)methyl]phenol 438-950-7 - - View substance registered dossier

In this table, you will find all public data submitted to ECHA in REACH registration dossiers by substance manufacturers, importers, or their representatives, as laid out by the REACH Regulation (see Understanding REACH regulation).

ECHA makes available this information as REACH registered substance factsheets, which contain the full set of non-confidential information from related registration dossiers for a substance. Depending on the number of registrations that have been made for a substance, one factsheet can thus represent data from anything between hundreds of registration dossiers in a joint submission, to data from just one registration dossier.

As noted in the Legal Notice of the ECHA website, ECHA does not give any guarantees or warranties regarding the quality and correctness of the published information. The information in the portal is published ‘as provided’ by industry, and its accuracy has not been verified by ECHA. ECHA is also not in a position to intervene with, edit or correct the published data; this can only be done by the registrant responsible for its submission. Please also note that the information may be protected and its use may require prior permission from its owner (see the ECHA website Legal Notice more details).

In the portal results table are presented:

  • Public substance identity – the best available non-confidential substance name, EC, and CAS numbers.
  • Registration status – indicating the calculated registration status for the whole factsheet: Active – is being manufactured or imported to the EEA by one or more registrants; Cease Manufacture - is no longer being manufactured or imported above 1 tone per calendar year. All registrants of the substance have reported a cease of manufacture or import; or No longer valid - no longer considered registered under REACH and not currently allowed to be manufactured or imported to the EEA, until the substance is registered again.
  • Registration type – indicating whether a given factsheet contains data from a REACH full registration, REACH intermediate registration, or only a limited set of data inherited from a NONS notification.
  • Submission type – indicating whether the data in a given factsheet was submitted jointly or individually.
  • Total tonnage band – calculated per factsheet from all contributing registrations, based on the estimated quantity of the substance placed on the market. Data is excluded from dossiers where the tonnage is claimed confidential, from Intermediate registration dossiers, and from NONs which have not been updated.
  • Last updated – indicating the date on which this registered substance factsheet was last modified with new or updated data, based on an industry submission.
  • Link to the full factsheet.

A subset of the key chemical properties (physico-chemical, environmental fate, ecotoxicological and toxicological data) of registered substances can be searched and accessed via the OECD eChemPortal.