Registered substances

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New Data Availability System

A new Data Availability System is being developed by ECHA. To begin with this system will take over the responsibility of making REACH registration data available, once it is ready. We expect the first version to be publicly available by the end of 2023.

Since ECHA aims to devote our maximum effort to this new system, we can no longer maintain REACH registration data on the current Dissemination Platform. As such once the IUCLID format change begins on 19th May 2023 we will no longer update REACH registered substance factsheets. The factsheets will remain online, but will not be updated.

New and updated REACH registration submissions, as well as all registrations on file, will be made available in the new system when it is ready. We will inform you of what you can expect in the new system, along with details of when and where to find it.

We appreciate your understanding in the meantime.

DISSEMINATION
PLATFORM

REACH - Registration, Evaluation, Authorisation and Restriction of Chemicals Regulation

Registered Substances Factsheets

Substances which have been registered and can be placed on the EEA market by those companies with a valid registration

Showing 701 - 800 of 26,862 results.

Name	EC / List no.	CAS no.	Registration Status	Registration type	Submission type	Total tonnage band	Last Updated	Details
(3R,4S,5S,6R,7R,9R,10E,11S,12R,13S,14R)-6-[(2S,3R,4S,6R)-4-(dimethylamino)-6-methyl-3-trimethylsilyloxyoxan-2-yl]oxy-10-(2-ethoxypropan-2-yloxyimino)-14-ethyl-12,13-dihydroxy-7-methoxy-4-[(2R,4R,5S,6S)-4-methoxy-4,6-dimethyl-5-trimethylsilyloxyoxan-2-yl]oxy-3,5,7,9,11,13-hexamethyl-oxacyclotetradecan-2-one	805-486-5	119665-62-2	Active	Intermediate	Joint	Intermediate use only	13-03-2017	View substance registered dossier
(3R,4S,5S,6R,7R,9R,10E,11S,12R,13S,14R)-6-[(2S,3R,4S,6R)-4-dimethylamino-3-hydroxy-6-methyloxan-2-yl]oxy-14-ethyl-7,12,13-trihydroxy-10-hydroxyimino-4-[(2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyloxan-2-yl]oxy-3,5,7,9,11,13-hexamethyl-1-oxacyclotetradecan-2-one	603-467-4	13127-18-9	Cease Manufacture	Intermediate	Individual	Cease manufacture	22-10-2010	View substance registered dossier
(3R,4S,5S,6R,7R,9R,10E,11S,12R,13S,14R)-6-[(2S,3R,4S,6R)-4-dimethylamino-3-hydroxy-6-methyloxan-2-yl]oxy-14-ethyl-7,12,13-trihydroxy-10-hydroxyimino-4-[(2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyloxan-2-yl]oxy-3,5,7,9,11,13-hexamethyl-1-oxacyclotetradecan-2-one	603-467-4	13127-18-9	Active	Intermediate	Joint	Intermediate use only	07-02-2022	View substance registered dossier
(3R,4S,5S,6R,7R,9R,10E,11S,12R,13S,14R)-6-{[(2S,3R,4S,6R)-4-(Dimethylamino)-3-hydroxy-6-methyltetrahydro-2H-pyran-2-yl]oxy}-14-ethyl-7,12,13-trihydroxy-10-(hydroxyimino)-4-{[(2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyltetrahydro-2H-pyran-2-yl]oxy}-3,5,7,9,11,13-hexamethyloxacyclotetradecan-2-one hydrochloride	607-864-3	26116-57-4	Active	Intermediate	Individual	Intermediate use only	02-05-2013	View substance registered dossier
(3R,4S,5S,6R,7R,9R,10E,11S,12R,13S,14R)-6-{[(2S,3R,4S,6R)-4-(Dimethylamino)-3-hydroxy-6-methyltetrahydro-2H-pyran-2-yl]oxy}-14-ethyl-7,12,13-trihydroxy-10-(hydroxyimino)-4-{[(2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyltetrahydro-2H-pyran-2-yl]oxy}-3,5,7,9,11,13-hexamethyloxacyclotetradecan-2-one hydrochloride	607-864-3	26116-57-4	Active	Intermediate	Individual	Intermediate use only	26-05-2014	View substance registered dossier
(3R,4S,6R,7R,9R,11S,12R,13S,14R)-6-{[4-(dimethylamino)-3-hydroxy-6-methyloxan-2-yl]oxy}-14-ethyl-12,13-dihydroxy-4-[(5-hydroxy-4-methoxy-4,6-dimethyloxan-2-yl)oxy]-10-(hydroxyimino)-7-methoxy-3,5,7,9,11,13-hexamethyl-1-oxacyclotetradecan-2-one	918-279-0	-	Active	Intermediate	Joint	Intermediate use only	26-04-2017	View substance registered dossier
(3R,5aS,6R,8aS,9R,12S,12aR)-3,6,9-trimethyloctahydro-3,12-epoxypyrano[4,3-j][1,2]benzodioxepin-10(3H)-one	700-290-5	63968-64-9	Active	Intermediate	Individual	Intermediate use only	15-11-2012	View substance registered dossier
(3R,5R)-tert-Butyl 7-[2-(4-fluorophenyl)-5-isopropyl-3-phenyl-4-(phenylcarbamoyl)-1H-pyrrol-1-yl]-3,5-dihydroxyheptanoate	603-817-6	134395-00-9	Active	Intermediate	Joint	Intermediate use only	28-09-2017	View substance registered dossier
(3R,5R,8R,9R,10S,13S,14S,17S)-17-(1-hydroxyethyl)-3,13-dimethylhexadecahydro-1H-cyclopenta[a]phenanthren-3-ol	887-813-1	1430063-92-5	Active	Intermediate	Joint	Intermediate use only	07-12-2022	View substance registered dossier
(3R,5S,6E)-methyl-7-(4-(4-fluorophenyl)-6-isopropyl-2-(N-methylmethylsulfonamido)pyrimidin-5-yl)-3,5-dihydroxyhept-6-enoate	604-568-6	147118-40-9	Active	Intermediate	Joint	Intermediate use only	17-01-2018	View substance registered dossier
(3R,5S,E)-tert-butyl 7-(4-(4-fluorophenyl)-6-isopropyl-2-(N-methylmethylsulfonamido)pyrimidin-5-yl)-3,5-dihydroxyhept-6-enoate	609-144-4	355806-00-7	Active	Intermediate	Joint	Intermediate use only	13-03-2020	View substance registered dossier
(3R,5Z)-3-METHYL-5-CYCLOPENTADECEN-1-ONE	851-742-4	464207-51-0	Active	Full	Joint	≥ 1 to < 10 tonnes	28-05-2020	View substance registered dossier
(3R,6R)-3,6-Dimethyl-1,4-dioxane-2,5-dione	603-436-5	13076-17-0	Active	Full	Joint	≥ 10 to < 100 tonnes	17-05-2022	View substance registered dossier
(3R,6S)-1-benzyl-6-methylpiperidin-3-amine acetyl-L-leucinate [1:1]	840-203-9	2295746-51-7	Active	Intermediate	Joint	Intermediate use only	24-11-2020	View substance registered dossier
(3R,7aR)-3-tert-butyl-1,5-dioxodihydro-1H-pyrrolo[1,2-c][1,3]oxazole-7a(5H)-carbaldehyde	812-036-1	1214741-19-1	Cease Manufacture	Intermediate	Individual	Cease manufacture	28-04-2016	View substance registered dossier
(3R,7aR)-3-tert-butyl-7a-{methoxy[(trimethylsilyl)oxy]methyl}dihydro-1H-pyrrolo[1,2-c][1,3]oxazole-1,5(6H)-dione	942-823-6	-	Cease Manufacture	Intermediate	Individual	Cease manufacture	03-11-2015	View substance registered dossier
(3R,7aS)-3-tert-butyldihydro-1H-pyrrolo[1,2-c]oxazole-1,5(6H)-dione	810-392-2	171284-84-7	Cease Manufacture	Intermediate	Individual	Cease manufacture	07-09-2015	View substance registered dossier
(3R-trans)-dihydro-2,5-dioxofuran-3,4-diyl diacetate	228-502-7	6283-74-5	Active	Intermediate	Joint	Intermediate use only	21-01-2022	View substance registered dossier
(3RS,3aRS,6SR,7aSR)-hexahydro-3,6-dimethyl-2(3H)-benzofuranone and (3RS,3aSR,6RS,7aRS)-hexahydro-3,6-dimethyl-2(3H)-benzofuranone	429-980-1	-	Active	NONS	Joint	Tonnage data confidential	15-12-2008	View substance registered dossier
(3S)-1,3,4-Trihydroxy-2-butanone	443-800-9	533-50-6	Active	Full	Joint	≥ 10 to < 100 tonnes	27-04-2023	View substance registered dossier
(3S)-1,3,4-Trihydroxy-2-butanone	443-800-9	533-50-6	Active	NONS	Joint	Tonnage data confidential	10-11-2008	View substance registered dossier
(3S)-2-Ethyl-3-hydroxy-2-[(2E)-2-(6-methoxy-3,4-dihydronaphtalen-1(2H)-ylidene)ethyl]cyclopentanone	692-111-1	14507-43-8	Active	Intermediate	Joint	Intermediate use only	18-01-2021	View substance registered dossier
(3S)-3,7-Dimethyl-1-octanol	814-059-2	68680-98-8	Active	Full	Joint	≥ 1 to < 10 tonnes	30-05-2018	View substance registered dossier
(3S)-3,7-dimethylocta-1,6-dien-1-yl acetate	946-529-9	1439355-19-7	Active	Intermediate	Joint	Intermediate use only	24-01-2018	View substance registered dossier
(3S)-3-hydroxypyrrolidin-2-one	676-349-3	34368-52-0	Active	Intermediate	Individual	Intermediate use only	12-11-2019	View substance registered dossier
(3S)-3-thiophen-2-ylsulfanylbutanoic acid	948-811-7	133359-80-5	Active	Intermediate	Joint	Intermediate use only	23-10-2018	View substance registered dossier
(3S)-3-{4-[8-(2,4-dichlorophenyl)-3-(methoxycarbonyl)-6,7-dihydro-5H-benzocyclohepten-9-yl]phenoxy}-1-(3-fluoropropyl)pyrrolidinium hydrogen oxalate	950-060-5	-	Active	Intermediate	Joint	Intermediate use only	15-01-2020	View substance registered dossier
(3S)-9,10-difluoro-2,3-dihidro-3-metil-7-oxo-7H-pyrido[1,2,3-de]-1,4-benzoxacine-6-carboxílic acid ethyl ester	691-244-2	106939-34-8	Active	Intermediate	Individual	Intermediate use only	12-06-2014	View substance registered dossier
(3S)-N,N-dimethyl-3-(naphthalen-1-yloxy)-3-(thiophen-2-yl)propan-1-amine ethanedioate	603-567-8	132335-47-8	Active	Intermediate	Individual	Intermediate use only	08-10-2009	View substance registered dossier
(3S,1R)-3-N-Boc-aminocyclopentan-1-ol	807-383-0	167465-99-8	Active	Intermediate	Joint	Intermediate use only	04-05-2018	View substance registered dossier
(3S,3S’)-Dineopentyl 4,4’-disulfanediylbis(3-(benzyloxycarbonylamino)butane-1-sulfonate	954-955-1	-	Active	Intermediate	Joint	Intermediate use only	27-09-2021	View substance registered dossier
(3S,4aS,8aS)-2-[(2R,3S)-3-amino-2-hydroxy-4-phenylbutyl]-N-tert-butyldecahydroisoquinoline-3-carboxamide PTH-AA	430-230-0	136522-17-3	Cease Manufacture	NONS	Individual	Cease manufacture	13-09-2010	View substance registered dossier
(3S,4aS,8aS)-N-tert-butyldecahydro-3-isoquinolinecarboxamide	420-380-5	136465-81-1	Active	NONS	Joint	Tonnage data confidential	10-11-2008	View substance registered dossier
(3S,4aS,8aS)-N-tert-butyldecahydro-3-isoquinolinecarboxamide	420-380-5	136465-81-1	Cease Manufacture	Intermediate	Individual	Cease manufacture	29-10-2012	View substance registered dossier
(3S,4R)-3-[(1,3-Benzodioxol-5-yloxy)methyl]-1-benzyl-4-(4-fluorophenyl)piperidine	929-011-7	-	Active	Intermediate	Joint	Intermediate use only	20-04-2018	View substance registered dossier
(3S,4R)-3-[(1,3-benzodioxol-5-yloxy)methyl]-4-(4-fluorophenyl)-1-methylpiperidine	924-787-3	110429-36-2	Active	Intermediate	Joint	Intermediate use only	08-03-2021	View substance registered dossier
(3S,4S)-3-hexyl-4-[(R)-2-hydroxytridecyl]-2-oxetanone THL-HBL	418-650-2	104872-06-2	Active	NONS	Joint	Tonnage data confidential	10-11-2008	View substance registered dossier
(3S,5R)-4-chloro-[5-(2,4-difluorophenyl)tetrahydro-5-(1H-1,2,4-triazol-1-ylmethyl)furan-3-yl]methylbenzenesulfonate	436-150-2	-	Active	Intermediate	Joint	Intermediate use only	16-05-2018	View substance registered dossier
(3S,5R)-4-chloro-[5-(2,4-difluorophenyl)tetrahydro-5-(1H-1,2,4-triazol-1-ylmethyl)furan-3-yl]methylbenzenesulfonate	436-150-2	-	Active	Intermediate	Joint	Intermediate use only	12-07-2013	View substance registered dossier
(3S,5R,8aS)-3-phenyl-3,5,6,7,8,8a-hexahydro-2H-oxazolo[3,2-a]pyridine-5-carbonitrile	634-598-5	106565-71-3	Cease Manufacture	Intermediate	Individual	Cease manufacture	15-10-2014	View substance registered dossier
(3S,5S)-5-[(1S,3S)-1-azido-3-{[4-methoxy-3-(3-methoxypropoxy)phenyl]methyl}-4-methylpentyl]-3-(propan-2-yl)oxolan-2-one	608-748-5	324763-46-4	Active	Intermediate	Joint	Intermediate use only	13-08-2014	View substance registered dossier
(3S,5S,6S,9R)-6-isopropyl-3,9-dimethyl-1,4- and (3S,5R,6S,9R)-6-isopropyl-3,9-dimethyl-1,4-	457-410-1	831213-72-0	Active	NONS	Joint	Tonnage data confidential	10-11-2008	View substance registered dossier
(3S,6E)- 3,7,11-trimethyldodeca-6,10-dien-1-ol	450-320-3	-	Active	Full	Joint	≥ 0 to < 10 tonnes	16-04-2018	View substance registered dossier
(3S,6E)- 3,7,11-trimethyldodeca-6,10-dien-1-ol	450-320-3	-	Active	NONS	Individual	Tonnage data confidential	10-11-2008	View substance registered dossier
(3S,6E)-3,7,11-trimethyl-dodeca-6,10-dienal	810-298-1	194934-66-2	Active	Full	Joint	≥ 1 to < 10 tonnes	07-09-2020	View substance registered dossier
(3S,6R,7E,9R,10R,12R,14S,15E,17E,19E,21S,23S,26R,27R,34aS)-9,10,12,13,14,21,22,23,24,25,26,27,32,33,34,34a-hexadecahydro-9,27-dihydroxy-3-[(1R)-2-[(1S,3R,4R)-4-hydroxy-3-methoxycyclohexyl]-1-methylethyl]-10,21-dimethoxy-6,8,12,14,20,26-hexamethyl-23,27-epoxy-3H-pyrido[2,1-c][1,4]-oxaazacyclohentriacontine-1,5,11,28,29(4H,6H,31H)-pentone	610-965-5	53123-88-9	Cease Manufacture	Intermediate	Individual	Cease manufacture	26-08-2014	View substance registered dossier
(3S,6R,9S,12R,15S,18R,21S,24R)-6,18-dibenzyl-3,9,15,21-tetraisobutyl-4,10,12,16,22,24-hexamethyl-1,7,13,19-tetraoxa-4,10,16,22-tetraazacyclo-tetracosane-2,5,8,11,14,17,20,23-octaone	444-350-6	133413-70-4	Active	Intermediate	Joint	Intermediate use only	24-09-2019	View substance registered dossier
(3S,6S,7R,8R)-8-Benzyl-3-{[(3-hydroxy-4-methoxypyridin-2-yl)carbonyl]amino}-6-methyl-4,9-dioxo-1,5-dioxonan-7-yl 2-methylpropanoate	844-009-5	167173-85-5	Active	Intermediate	Joint	Intermediate use only	04-02-2022	View substance registered dossier
(3S-cis)-3,6-dimethyl-1,4-dioxane-2,5-dione	224-832-0	4511-42-6	Active	Full	Joint	≥ 1 000 to < 10 000 tonnes	01-08-2022	View substance registered dossier
(3S-cis)-3,6-dimethyl-1,4-dioxane-2,5-dione	224-832-0	4511-42-6	Cease Manufacture	Full	Individual	Cease manufacture	17-08-2015	View substance registered dossier
(3S-trans)-phenyl-3-[(1,3-benzodioxol-5-yloxy)methyl]-4-(4-fluorophenyl)-1-piperidinecarboxylate	430-510-2	-	Active	NONS	Joint	Tonnage data confidential	10-11-2008	View substance registered dossier
(3Z)-hex-3-en-1-yl 2-methylprop-2-en-1-yl ether	439-790-0	292605-05-1	Active	Full	Individual	≥ 0 to < 10 tonnes	18-01-2013	View substance registered dossier
(3Z)-hex-3-en-1-yl cyclopropanecarboxylate	425-200-9	188570-78-7	Active	Full	Joint	≥ 1 tonnes	17-12-2012	View substance registered dossier
(3α,5β,7β)-3,7-Dihydroxy-24-norcholane-23-nitrile	828-107-5	118316-12-4	Active	Intermediate	Joint	Intermediate use only	05-09-2018	View substance registered dossier
(3β)-17-(1,1,1-trifluoromethanesulfonate)-Androsta-5,16-diene-3,17-diol, 3-(2,2,2-trifluoroacetate)	840-627-4	1802323-89-2	Active	Intermediate	Joint	Intermediate use only	26-06-2019	View substance registered dossier
(3β)-3-[(2,2,2-trifluoroacetyl)oxy]-Androst-5-en-17-one	840-626-9	3798-17-2	Active	Intermediate	Joint	Intermediate use only	26-06-2019	View substance registered dossier
(3β,20β)-3-acetoxy-11-oxoolean-12-en-29-oic acid	228-475-1	6277-14-1	Active	Full	Joint	≥ 0 to < 10 tonnes	27-06-2019	View substance registered dossier
(3β,5Z,7E)-9,10-secocholesta-5,7,10(19)-trien-3-yl butyrate	250-567-5	31316-20-8	Active	Intermediate	Joint	Intermediate use only	24-01-2022	View substance registered dossier
(4'-methyl-3-fluoro[1,1'-biphenyl]-4-yl)-boronic acid	813-651-8	1698890-39-9	Active	Full	Joint	≥ 0 to < 10 tonnes	05-07-2022	View substance registered dossier
(4,5-dibromo-1H-pyrrol-2-yl)(phenyl)methanone	700-338-5	50372-61-7	Active	Intermediate	Joint	Intermediate use only	05-10-2016	View substance registered dossier
(4-(1-methylethyl)phenyl)-(4-methylphenyl)iodonium tetrakis(pentafluorophenyl)borate (1-) PHOTOAMORCEUR 22074; RHODORSIL PHOTOINITIATOR 2074; TEPBI	422-960-3	178233-72-2	Active	NONS	Joint	Tonnage data confidential	04-01-2023	View substance registered dossier
(4-(4-(4-dimethylaminobenzyliden-1-yl)-3-methyl-5-oxo-2-pyrazolin-1-yl)benzoic acid (ALKYLAMINOARYLALKYLIDENYL)PYRAZOLINONE	410-430-4	117573-89-4	Active	NONS	Joint	Tonnage data confidential	10-11-2008	View substance registered dossier
(4-(4-amino-6,7-dimethoxyquinazolin-2-yl)piperazin-1-yl)(tetrahydrofuran-2-yl)methanone	613-265-8	63590-64-7	Active	Intermediate	Joint	Intermediate use only	25-07-2018	View substance registered dossier
(4-(4-aminophenyl)(4-iminocyclohexa-2,5-dienylidene)methyl)-2-methylaniline hydrochloride	211-189-6	632-99-5	Cease Manufacture	Full	Joint	Cease manufacture	25-03-2018	View substance registered dossier
(4-(5-Oxo-4,5-dihydro-1,2,4-oxadiazol-3-yl)-phenylamino)-acetic acid ethyl ester	927-587-4	872728-83-1	Active	Intermediate	Joint	Intermediate use only	28-07-2016	View substance registered dossier
(4-(5-Oxo-4,5-dihydro-1,2,4-oxadiazole-3-yl)phenylamino)acetic acid	460-450-2	872728-82-0	Active	Intermediate	Joint	Intermediate use only	17-05-2019	View substance registered dossier
(4-(6-diethylamino-2-methylpyridin-3-yl)imino-4,5-dihydro-3-methyl-1-(4-methylphenyl)-1H-pyrazol-5-one	427-070-9	-	Active	NONS	Individual	Tonnage data confidential	10-11-2008	View substance registered dossier
(4-6) PEPTIDE	427-550-8	-	Active	NONS	Joint	Tonnage data confidential	10-11-2008	View substance registered dossier
(4-acetamido-2,2,6,6-tetramethyl-1-piperidinyl)oxidanyl;N-(2,2,6,6-tetramethyl-1-oxylpiperidin-4-yl)acetamide	423-840-3	14691-89-5	Cease Manufacture	NONS	Individual	Cease manufacture	10-11-2008	View substance registered dossier
(4-acetamido-2,2,6,6-tetramethyl-1-piperidinyl)oxidanyl;N-(2,2,6,6-tetramethyl-1-oxylpiperidin-4-yl)acetamide	423-840-3	14691-89-5	Active	Full	Joint	≥ 0 tonnes	19-12-2022	View substance registered dossier
(4-amino-1-hydroxy-1-phosphonobutyl)phosphonic acid;hydrate	680-378-7	138624-11-0	Active	Full	Joint	≥ 1 to < 10 tonnes	02-02-2018	View substance registered dossier
(4-amino-2-chloro-5-methylphenyl)(4-chlorophenyl)acetonitrile	262-792-6	61437-85-2	Active	Intermediate	Joint	Intermediate use only	09-03-2018	View substance registered dossier
(4-aminophenyl)-N-methylmethylenesulfonamide hydrochloride SULPHONAMIDO-ANILINE	406-010-5	88918-84-7	Active	NONS	Joint	Tonnage data confidential	10-11-2008	View substance registered dossier
(4-benzylpiperazin-1-yl)(cyclopropyl)methanone hydrochloride	816-907-7	1294454-93-5	Cease Manufacture	Intermediate	Joint	Cease manufacture	28-05-2020	View substance registered dossier
(4-butoxy-2,3-difluorophenyl)boronic acid	692-793-0	156487-12-6	Active	Full	Joint	≥ 1 to < 10 tonnes	18-10-2022	View substance registered dossier
(4-carboxybutyl)triphenylphosphonium bromide	241-782-5	17814-85-6	Active	Intermediate	Joint	Intermediate use only	20-07-2022	View substance registered dossier
(4-Chloro-2-fluoro-phenyl)-acetonitrile	642-783-7	75279-53-7	Cease Manufacture	Intermediate	Individual	Cease manufacture	30-03-2016	View substance registered dossier
(4-Chloro-3-(4-ethoxybenzyl)phenyl)((3aS,5R,6S,6aS)-6-hydroxy-2,2-dimethyltetrahydrofuro[2,3-d][1,3]dioxol-5-yl)methanone	695-300-7	1103738-30-2	Active	Intermediate	Joint	Intermediate use only	24-11-2020	View substance registered dossier
(4-chlorophenyl)-(2,2,8-trimethyl-4H-[1,3]dioxino[4,5-c]pyridin-5-yl)methanol	814-124-5	133545-64-9	Active	Intermediate	Joint	Intermediate use only	10-05-2017	View substance registered dossier
(4-chlorophenyl)hydrazine	214-029-3	1073-69-4	No longer Valid	Intermediate	Individual	No longer valid	13-11-2013	View substance registered dossier
(4-chlorophenyl)hydrazine	214-029-3	1073-69-4	Active	Intermediate	Individual	Intermediate use only	28-09-2010	View substance registered dossier
(4-cyclopropyl-6-methyl-pyrimidin-5-yl)boronic acid	826-639-2	1817776-86-5	Cease Manufacture	Intermediate	Joint	Cease manufacture	20-07-2020	View substance registered dossier
(4-ethoxyphenyl)(3-(4-fluoro-3-phenoxyphenyl)propyl)dimethylsilane SILANEOPHAN	405-020-7	105024-66-6	Cease Manufacture	NONS	Joint	Cease manufacture	10-11-2008	View substance registered dossier
(4-hydrazinophenyl)-N-methylmethanesulfonamide hydrochloride SULPHAZINE	406-090-1	81880-96-8	No longer Valid	NONS	Individual	No longer valid	10-11-2008	View substance registered dossier
(4-methoxybiphenyl-3-yl)hydrazine hydrochloride	924-885-6	-	Active	Intermediate	Joint	Intermediate use only	22-10-2012	View substance registered dossier
(4-Methoxyphenyl)diphenylsulfoniumnonaflate	435-570-3	-	Active	NONS	Joint	Tonnage data confidential	24-06-2009	View substance registered dossier
(4-methylphenyl)mesitylene sulfonate KAYAKU TG-MC	407-530-5	67811-06-7	No longer Valid	NONS	Individual	No longer valid	10-11-2008	View substance registered dossier
(4-nitrophenyl)methanesulfonyl chloride	609-806-2	4025-75-6	Active	Intermediate	Individual	Intermediate use only	18-12-2019	View substance registered dossier
(4-nitrophenyl)methyl [6R,(6α,7β)]-[3-hydroxy-5,8-dioxo-7-(phenoxyacetylamino)-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate] ENOL SULFOXIDE ESTER	411-820-7	-	Active	NONS	Individual	Tonnage data confidential	10-11-2008	View substance registered dossier
(4-nonylphenoxy)acetic acid	221-486-2	3115-49-9	Active	Full	Joint	≥ 100 to < 1 000 tonnes	04-07-2014	View substance registered dossier
(4-phenylbutyl)phosphinic acid	420-450-5	86552-32-1	Active	Intermediate	Joint	Intermediate use only	09-12-2013	View substance registered dossier
(4-pyridylmethyl)amine	223-092-6	3731-53-1	Active	Intermediate	Joint	Intermediate use only	19-02-2018	View substance registered dossier
(4-pyridylthio)acetyl chloride hydrochloride	248-348-4	27230-51-9	Active	Intermediate	Joint	Intermediate use only	25-10-2021	View substance registered dossier
(4-tert-butyl-2,6-dimethylphenyl)acetonitrile	284-183-4	84803-57-6	Active	Intermediate	Joint	Intermediate use only	30-07-2015	View substance registered dossier
(4-vinylphenyl)methyl-2-[(1Z)-1-aza-3-methyl-2-(4-methylthiophenyl)-3-morpholin-4-ylbut-1-enyloxy]acetate	453-050-4	-	Active	NONS	Individual	Tonnage data confidential	04-02-2011	View substance registered dossier
(4aR, 8aR)-1-bromo-4a,5,9,10,11,12-hexahydro-3-methoxy-6H-benzofuro[3a,3,2-ef] [2]benzazepin-6-one hydrochloride (1:1)	700-867-1	-	Active	Full	Joint	≥ 1 to < 10 tonnes	11-06-2020	View substance registered dossier
(4aR,8aR)-4a,5,9,10,11,12-hexahydro-3-methoxy-11-methyl-6H-benzofuro[3a,3,2-ef][2]benzazepin-6-one	428-690-2	1668-86-6	Cease Manufacture	NONS	Individual	Cease manufacture	23-11-2010	View substance registered dossier
(4aR,4bS,5S,6aS,6bS,9aR,10aS,10bS)-6b-Acetyl-5-hydroxy-4a,6a,8-trimethyl-4a,4b,5,6,6a,6b,9a,10,10a,10b,11,12-dodecahydro-2H-naphtho[2',1':4,5]indeno[1,2-d][1,3]oxazol-2-one	680-670-4	13649-88-2	Active	Intermediate	Joint	Intermediate use only	10-08-2021	View substance registered dossier
(4aR,4bS,6aS,7aS,8aS,8bR,8cR)-2-methoxy-4a,6a-dimethyl-4,4a,4b,5,6,6a,7a,8,8a,8b,8c,9-dodecahydrocyclopropa[4,5]cyclopenta[1,2-a]phenanthren-7(3H)-one	607-934-3	26441-40-7	Active	Intermediate	Joint	Intermediate use only	29-04-2020	View substance registered dossier
(4aR,4bS,6aS,7S,7aS,8aS,8bR,8cR)-7-[2-(1,3-dioxolan-2-yl)ethyl]-2-methoxy-4a,6a-dimethyl-3,4,4a,4b,5,6,6a,7,7a,8,8a,8b,8c,9-tetradecahydrocyclopropa[4,5]cyclopenta[1,2-a]phenanthren-7-ol	618-226-9	889652-22-6	Active	Intermediate	Joint	Intermediate use only	05-05-2020	View substance registered dossier

Showing 701 - 800 of 26,862 results.

Registrant/Supplier	Address	Country	Registration Status	Name	EC / List no.	CAS no.	Last update year	Details
Ercros SA	Avenida Diagonal 593-595 08014 Barcelona Spain	Spain	Active	(3R,4S,5S,6R,7R,9R,10E,11S,12R,13S,14R)-6-[(2S,3R,4S,6R)-4-(dimethylamino)-6-methyl-3-trimethylsilyloxyoxan-2-yl]oxy-10-(2-ethoxypropan-2-yloxyimino)-14-ethyl-12,13-dihydroxy-7-methoxy-4-[(2R,4R,5S,6S)-4-methoxy-4,6-dimethyl-5-trimethylsilyloxyoxan-2-yl]oxy-3,5,7,9,11,13-hexamethyl-oxacyclotetradecan-2-one	805-486-5	119665-62-2	-	View substance registered dossier
Hovione FarmaCiencia SA	Sete Casas 2674-506 Loures Portugal	Portugal	Cease Manufacture	(3R,4S,5S,6R,7R,9R,10E,11S,12R,13S,14R)-6-[(2S,3R,4S,6R)-4-dimethylamino-3-hydroxy-6-methyloxan-2-yl]oxy-14-ethyl-7,12,13-trihydroxy-10-hydroxyimino-4-[(2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyloxan-2-yl]oxy-3,5,7,9,11,13-hexamethyl-1-oxacyclotetradecan-2-one	603-467-4	13127-18-9	2017	View substance registered dossier
EUROAPI FRANCE	15 rue Traversière 75012 Paris France	France	Active	(3R,4S,5S,6R,7R,9R,10E,11S,12R,13S,14R)-6-[(2S,3R,4S,6R)-4-dimethylamino-3-hydroxy-6-methyloxan-2-yl]oxy-14-ethyl-7,12,13-trihydroxy-10-hydroxyimino-4-[(2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyloxan-2-yl]oxy-3,5,7,9,11,13-hexamethyl-1-oxacyclotetradecan-2-one	603-467-4	13127-18-9	2017; 2021; 2022	View substance registered dossier
Sandoz Industrial Products SA	Ctra. Granollers - Cardedeu C-251, Km 4 08520 Les Franqueses del Vallés Catalunya Spain	Spain	Active	(3R,4S,5S,6R,7R,9R,10E,11S,12R,13S,14R)-6-{[(2S,3R,4S,6R)-4-(Dimethylamino)-3-hydroxy-6-methyltetrahydro-2H-pyran-2-yl]oxy}-14-ethyl-7,12,13-trihydroxy-10-(hydroxyimino)-4-{[(2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyltetrahydro-2H-pyran-2-yl]oxy}-3,5,7,9,11,13-hexamethyloxacyclotetradecan-2-one hydrochloride	607-864-3	26116-57-4	-	View substance registered dossier
Pliva Hrvatska doo	Prilaz baruna Filipovića 25 10000 Zagreb Croatia	Croatia	Active	(3R,4S,5S,6R,7R,9R,10E,11S,12R,13S,14R)-6-{[(2S,3R,4S,6R)-4-(Dimethylamino)-3-hydroxy-6-methyltetrahydro-2H-pyran-2-yl]oxy}-14-ethyl-7,12,13-trihydroxy-10-(hydroxyimino)-4-{[(2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyltetrahydro-2H-pyran-2-yl]oxy}-3,5,7,9,11,13-hexamethyloxacyclotetradecan-2-one hydrochloride	607-864-3	26116-57-4	-	View substance registered dossier
Ercros SA	Avenida Diagonal 593-595 08014 Barcelona Spain	Spain	Active	(3R,4S,6R,7R,9R,11S,12R,13S,14R)-6-{[4-(dimethylamino)-3-hydroxy-6-methyloxan-2-yl]oxy}-14-ethyl-12,13-dihydroxy-4-[(5-hydroxy-4-methoxy-4,6-dimethyloxan-2-yl)oxy]-10-(hydroxyimino)-7-methoxy-3,5,7,9,11,13-hexamethyl-1-oxacyclotetradecan-2-one	918-279-0	-	-	View substance registered dossier
Huvepharma Italia s.r.l.	Via Roberto Lepetit, 142 12075 GARESSIO (CN) Italy	Italy	Active	(3R,5aS,6R,8aS,9R,12S,12aR)-3,6,9-trimethyloctahydro-3,12-epoxypyrano[4,3-j][1,2]benzodioxepin-10(3H)-one	700-290-5	63968-64-9	2009; 2010; 2012	View substance registered dossier
Krka, d. d., Novo mesto	Smarjeska cesta 6 SI-8501 Novo mesto Slovenia	Slovenia	Active	(3R,5R)-tert-Butyl 7-[2-(4-fluorophenyl)-5-isopropyl-3-phenyl-4-(phenylcarbamoyl)-1H-pyrrol-1-yl]-3,5-dihydroxyheptanoate	603-817-6	134395-00-9	-	View substance registered dossier
F.I.S. Fabbrica Italiana Sintetici S.p.a.	Viale Milano, 26 36075 Montecchio Maggiore (VI) Veneto Italy	Italy	Active	(3R,5R,8R,9R,10S,13S,14S,17S)-17-(1-hydroxyethyl)-3,13-dimethylhexadecahydro-1H-cyclopenta[a]phenanthren-3-ol	887-813-1	1430063-92-5	-	View substance registered dossier
Lek Pharmaceuticals d.d.	Verovskova 57 1526 Ljubljana Slovenia	Slovenia	Active	(3R,5S,6E)-methyl-7-(4-(4-fluorophenyl)-6-isopropyl-2-(N-methylmethylsulfonamido)pyrimidin-5-yl)-3,5-dihydroxyhept-6-enoate	604-568-6	147118-40-9	2015; 2018	View substance registered dossier
EGIS Pharmaceuticals PLC	Keresztúri út 30-38 H-1106 Budapest Hungary	Hungary	Active	(3R,5S,6E)-methyl-7-(4-(4-fluorophenyl)-6-isopropyl-2-(N-methylmethylsulfonamido)pyrimidin-5-yl)-3,5-dihydroxyhept-6-enoate	604-568-6	147118-40-9	-	View substance registered dossier
Lek Pharmaceuticals d.d.	Verovskova 57 1526 Ljubljana Slovenia	Slovenia	Active	(3R,5S,E)-tert-butyl 7-(4-(4-fluorophenyl)-6-isopropyl-2-(N-methylmethylsulfonamido)pyrimidin-5-yl)-3,5-dihydroxyhept-6-enoate	609-144-4	355806-00-7	2020	View substance registered dossier
EGIS Pharmaceuticals PLC	Keresztúri út 30-38 H-1106 Budapest Hungary	Hungary	Active	(3R,5S,E)-tert-butyl 7-(4-(4-fluorophenyl)-6-isopropyl-2-(N-methylmethylsulfonamido)pyrimidin-5-yl)-3,5-dihydroxyhept-6-enoate	609-144-4	355806-00-7	-	View substance registered dossier
FIRMENICH GRASSE SAS OR 1	Parc Industriel Les Bois de Grasse 06130 Grasse France	France	Active	(3R,5Z)-3-METHYL-5-CYCLOPENTADECEN-1-ONE	851-742-4	464207-51-0	-	View substance registered dossier
TotalEnergies Corbion BV	Stadhuisplein 70 4203 NS Gorinchem Netherlands	Netherlands	Active	(3R,6R)-3,6-Dimethyl-1,4-dioxane-2,5-dione	603-436-5	13076-17-0	-	View substance registered dossier
Purac Biochem bv	Arkelsedijk 46 4206AC Gorinchem Netherlands	Netherlands	Active	(3R,6R)-3,6-Dimethyl-1,4-dioxane-2,5-dione	603-436-5	13076-17-0	2011; 2015; 2022	View substance registered dossier
Evonik Operations GmbH	Rellinghauser Straße 1-11 45128 Essen Germany	Germany	Active	(3R,6R)-3,6-Dimethyl-1,4-dioxane-2,5-dione	603-436-5	13076-17-0	-	View substance registered dossier
Pfizer Ireland Pharmaceuticals	n/a P43 X336 Ringaskiddy Cork Ireland	Ireland	Active	(3R,6S)-1-benzyl-6-methylpiperidin-3-amine acetyl-L-leucinate [1:1]	840-203-9	2295746-51-7	2020	View substance registered dossier
MINAKEM Beuvry Production SAS	145, Chemin des Lilas 59310 Beuvry-la-Forêt France	France	Cease Manufacture	(3R,7aR)-3-tert-butyl-1,5-dioxodihydro-1H-pyrrolo[1,2-c][1,3]oxazole-7a(5H)-carbaldehyde	812-036-1	1214741-19-1	2019	View substance registered dossier
MINAKEM Beuvry Production SAS	145, Chemin des Lilas 59310 Beuvry-la-Forêt France	France	Cease Manufacture	(3R,7aR)-3-tert-butyl-7a-{methoxy[(trimethylsilyl)oxy]methyl}dihydro-1H-pyrrolo[1,2-c][1,3]oxazole-1,5(6H)-dione	942-823-6	-	2019	View substance registered dossier
MINAKEM Beuvry Production SAS	145, Chemin des Lilas 59310 Beuvry-la-Forêt France	France	Cease Manufacture	(3R,7aS)-3-tert-butyldihydro-1H-pyrrolo[1,2-c]oxazole-1,5(6H)-dione	810-392-2	171284-84-7	2019	View substance registered dossier
All'Chem	rue Marceau 03108 MONTLUCON CEDEX France	France	Active	(3R-trans)-dihydro-2,5-dioxofuran-3,4-diyl diacetate	228-502-7	6283-74-5	2018	View substance registered dossier
EUROAPI FRANCE	15 rue Traversière 75012 Paris France	France	Active	(3R-trans)-dihydro-2,5-dioxofuran-3,4-diyl diacetate	228-502-7	6283-74-5	2021; 2022	View substance registered dossier
-	-	-	-	(3RS,3aRS,6SR,7aSR)-hexahydro-3,6-dimethyl-2(3H)-benzofuranone and (3RS,3aSR,6RS,7aRS)-hexahydro-3,6-dimethyl-2(3H)-benzofuranone	429-980-1	-	-	View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant UK competent national authority.	-	-	Active	(3RS,3aRS,6SR,7aSR)-hexahydro-3,6-dimethyl-2(3H)-benzofuranone and (3RS,3aSR,6RS,7aRS)-hexahydro-3,6-dimethyl-2(3H)-benzofuranone	429-980-1	-	-	View substance registered dossier
[Confidential]	-	-	-	(3S)-1,3,4-Trihydroxy-2-butanone	443-800-9	533-50-6	-	View substance registered dossier
SpecChem GmbH	Schiessstr. 55 40549 Düsseldorf Germany	Germany	Active	(3S)-1,3,4-Trihydroxy-2-butanone	443-800-9	533-50-6	-	View substance registered dossier
Givaudan France Fragrances SA	19-23, Voie des Bans, B.P. 98 95102 Argenteuil France	France	Active	(3S)-1,3,4-Trihydroxy-2-butanone	443-800-9	533-50-6	2023	View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant Italian competent national authority.	-	-	Active	(3S)-1,3,4-Trihydroxy-2-butanone	443-800-9	533-50-6	-	View substance registered dossier
DSM Nutritional Products GmbH	Emil-Barell-Str. 3 79639 Grenzach-Wyhlen Germany	Germany	Active	(3S)-1,3,4-Trihydroxy-2-butanone	443-800-9	533-50-6	-	View substance registered dossier
Gedeon Richter Plc.	Gyomroi ut 19-21 1103 Budapest Hungary	Hungary	Active	(3S)-2-Ethyl-3-hydroxy-2-[(2E)-2-(6-methoxy-3,4-dihydronaphtalen-1(2H)-ylidene)ethyl]cyclopentanone	692-111-1	14507-43-8	2021	View substance registered dossier
TAKASAGO TEPL-OR(1)	12 rue Torricelli 75017 Paris France	France	Active	(3S)-3,7-Dimethyl-1-octanol	814-059-2	68680-98-8	-	View substance registered dossier
TAKASAGO TICSA-Producer/Importer	Avenida de Mazarrón, 49 30120 El Palmar Murcia Spain	Spain	Active	(3S)-3,7-dimethylocta-1,6-dien-1-yl acetate	946-529-9	1439355-19-7	-	View substance registered dossier
Bayer AG	Kaiser-Wilhelm-Allee 1 51373 Leverkusen Germany	Germany	Active	(3S)-3-hydroxypyrrolidin-2-one	676-349-3	34368-52-0	-	View substance registered dossier
DUKE CHEM, S.A.	Avgda. Mare de Déu de Montserrat, 93 - 99 Pol. Ind. Sant Pere Molanta 08799 Olèrdola Barcelona Spain	Spain	Active	(3S)-3-thiophen-2-ylsulfanylbutanoic acid	948-811-7	133359-80-5	-	View substance registered dossier
sanofi chimie	82 avenue Raspail 94250 Gentilly France	France	Active	(3S)-3-{4-[8-(2,4-dichlorophenyl)-3-(methoxycarbonyl)-6,7-dihydro-5H-benzocyclohepten-9-yl]phenoxy}-1-(3-fluoropropyl)pyrrolidinium hydrogen oxalate	950-060-5	-	-	View substance registered dossier
QUIMICA SINTETICA, S.A.	C/ Dulcinea, s/n 28805 Alcalá de Henares Madrid Spain	Spain	Active	(3S)-9,10-difluoro-2,3-dihidro-3-metil-7-oxo-7H-pyrido[1,2,3-de]-1,4-benzoxacine-6-carboxílic acid ethyl ester	691-244-2	106939-34-8	2014	View substance registered dossier
Saneca Pharmaceuticals a.s.	Nitrianska 100 92027 Hlohovec Slovakia	Slovakia	Active	(3S)-N,N-dimethyl-3-(naphthalen-1-yloxy)-3-(thiophen-2-yl)propan-1-amine ethanedioate	603-567-8	132335-47-8	2009	View substance registered dossier
PCAS	21 Chemin de la Sauvegarde 21 Ecully Parc - CS33167 69134 ECULLY France	France	Active	(3S,1R)-3-N-Boc-aminocyclopentan-1-ol	807-383-0	167465-99-8	-	View substance registered dossier
Curia France SAS	ZI de Laville 47240 BON-ENCONTRE France	France	Active	(3S,1R)-3-N-Boc-aminocyclopentan-1-ol	807-383-0	167465-99-8	-	View substance registered dossier
ORGAPHARM	Rue du Moulin de la Canne 45300 PITHIVIERS France	France	Active	(3S,3S’)-Dineopentyl 4,4’-disulfanediylbis(3-(benzyloxycarbonylamino)butane-1-sulfonate	954-955-1	-	-	View substance registered dossier
Roche Ireland Limited	Clarehill . Clarecastle Ireland	Ireland	Cease Manufacture	(3S,4aS,8aS)-2-[(2R,3S)-3-amino-2-hydroxy-4-phenylbutyl]-N-tert-butyldecahydroisoquinoline-3-carboxamide	430-230-0	136522-17-3	2020	View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant Dutch competent national authority.	-	-	Active	(3S,4aS,8aS)-N-tert-butyldecahydro-3-isoquinolinecarboxamide	420-380-5	136465-81-1	-	View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant UK competent national authority.	-	-	Active	(3S,4aS,8aS)-N-tert-butyldecahydro-3-isoquinolinecarboxamide	420-380-5	136465-81-1	-	View substance registered dossier
Roche Ireland Limited	Clarehill . Clarecastle Ireland	Ireland	Cease Manufacture	(3S,4aS,8aS)-N-tert-butyldecahydro-3-isoquinolinecarboxamide	420-380-5	136465-81-1	2020	View substance registered dossier
Gedeon Richter Plc.	Gyomroi ut 19-21 1103 Budapest Hungary	Hungary	Active	(3S,4R)-3-[(1,3-Benzodioxol-5-yloxy)methyl]-1-benzyl-4-(4-fluorophenyl)piperidine	929-011-7	-	-	View substance registered dossier
Thermofisher Scientific Cork Ltd.	Currabinny P43 AY66 Carrigaline Co. Cork Ireland	Ireland	Active	(3S,4R)-3-[(1,3-benzodioxol-5-yloxy)methyl]-4-(4-fluorophenyl)-1-methylpiperidine	924-787-3	110429-36-2	2021	View substance registered dossier
CHEMI S.p.A.	Via dei lavoratori, 54 20092 Cinisello balsamo Lombardia Italy	Italy	Active	(3S,4R)-3-[(1,3-benzodioxol-5-yloxy)methyl]-4-(4-fluorophenyl)-1-methylpiperidine	924-787-3	110429-36-2	-	View substance registered dossier
F.I.S. Fabbrica Italiana Sintetici S.p.a.	Viale Milano, 26 36075 Montecchio Maggiore (VI) Veneto Italy	Italy	Active	(3S,4S)-3-hexyl-4-[(R)-2-hydroxytridecyl]-2-oxetanone	418-650-2	104872-06-2	-	View substance registered dossier
Patheon Austria GmbH & Co KG	St. Peterstrasse 25 A-4020 Linz Austria	Austria	Cease Manufacture	(3S,4S)-3-hexyl-4-[(R)-2-hydroxytridecyl]-2-oxetanone	418-650-2	104872-06-2	2022	View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant Austrian competent national authority.	-	-	No longer Valid	(3S,4S)-3-hexyl-4-[(R)-2-hydroxytridecyl]-2-oxetanone	418-650-2	104872-06-2	2022	View substance registered dossier
MINAKEM Beuvry Production SAS	145, Chemin des Lilas 59310 Beuvry-la-Forêt France	France	Active	(3S,5R)-4-chloro-[5-(2,4-difluorophenyl)tetrahydro-5-(1H-1,2,4-triazol-1-ylmethyl)furan-3-yl]methylbenzenesulfonate	436-150-2	-	-	View substance registered dossier
MSD International GmbH	Ballydine - Kilsheelan 0 Clonmel Ireland	Ireland	Active	(3S,5R)-4-chloro-[5-(2,4-difluorophenyl)tetrahydro-5-(1H-1,2,4-triazol-1-ylmethyl)furan-3-yl]methylbenzenesulfonate	436-150-2	-	2011; 2015	View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant Irish competent national authority.	-	-	Active	(3S,5R)-4-chloro-[5-(2,4-difluorophenyl)tetrahydro-5-(1H-1,2,4-triazol-1-ylmethyl)furan-3-yl]methylbenzenesulfonate	436-150-2	-	-	View substance registered dossier
[Confidential]	-	-	-	(3S,5R)-4-chloro-[5-(2,4-difluorophenyl)tetrahydro-5-(1H-1,2,4-triazol-1-ylmethyl)furan-3-yl]methylbenzenesulfonate	436-150-2	-	-	View substance registered dossier
CU Chemie Uetikon GmbH	Raiffeisenstrasse 4 77933 Lahr Germany	Germany	Cease Manufacture	(3S,5R,8aS)-3-phenyl-3,5,6,7,8,8a-hexahydro-2H-oxazolo[3,2-a]pyridine-5-carbonitrile	634-598-5	106565-71-3	2020	View substance registered dossier
Novartis Integrated Services Limited	Ringaskiddy P43 FR63 Ringaskiddy Co. Cork Ireland	Ireland	Active	(3S,5S)-5-[(1S,3S)-1-azido-3-{[4-methoxy-3-(3-methoxypropoxy)phenyl]methyl}-4-methylpentyl]-3-(propan-2-yl)oxolan-2-one	608-748-5	324763-46-4	2014	View substance registered dossier
Novartis Grimsby Limited	Moody Lane, Pyewipe DN31 2SR Grimsby N.E. Lincolnshire United Kingdom	United Kingdom	No longer Valid	(3S,5S)-5-[(1S,3S)-1-azido-3-{[4-methoxy-3-(3-methoxypropoxy)phenyl]methyl}-4-methylpentyl]-3-(propan-2-yl)oxolan-2-one	608-748-5	324763-46-4	2021	View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant UK competent national authority.	-	-	Active	(3S,5S,6S,9R)-6-isopropyl-3,9-dimethyl-1,4- and (3S,5R,6S,9R)-6-isopropyl-3,9-dimethyl-1,4-	457-410-1	831213-72-0	-	View substance registered dossier
-	-	-	-	(3S,5S,6S,9R)-6-isopropyl-3,9-dimethyl-1,4- and (3S,5R,6S,9R)-6-isopropyl-3,9-dimethyl-1,4-	457-410-1	831213-72-0	-	View substance registered dossier
TAKASAGO TEPL-OR(1)	12 rue Torricelli 75017 Paris France	France	Active	(3S,6E)- 3,7,11-trimethyldodeca-6,10-dien-1-ol	450-320-3	-	2018	View substance registered dossier
-	-	-	-	(3S,6E)- 3,7,11-trimethyldodeca-6,10-dien-1-ol	450-320-3	-	-	View substance registered dossier
TAKASAGO TEPL-Importer	12 rue Torricelli 75017 Paris France	France	Active	(3S,6E)-3,7,11-trimethyl-dodeca-6,10-dienal	810-298-1	194934-66-2	2020	View substance registered dossier
TAKASAGO TEPL-OR(1)	12 rue Torricelli 75017 Paris France	France	Active	(3S,6E)-3,7,11-trimethyl-dodeca-6,10-dienal	810-298-1	194934-66-2	-	View substance registered dossier
Lek Pharmaceuticals d.d.	Verovskova 57 1526 Ljubljana Slovenia	Slovenia	Cease Manufacture	(3S,6R,7E,9R,10R,12R,14S,15E,17E,19E,21S,23S,26R,27R,34aS)-9,10,12,13,14,21,22,23,24,25,26,27,32,33,34,34a-hexadecahydro-9,27-dihydroxy-3-[(1R)-2-[(1S,3R,4R)-4-hydroxy-3-methoxycyclohexyl]-1-methylethyl]-10,21-dimethoxy-6,8,12,14,20,26-hexamethyl-23,27-epoxy-3H-pyrido[2,1-c][1,4]-oxaazacyclohentriacontine-1,5,11,28,29(4H,6H,31H)-pentone	610-965-5	53123-88-9	2017	View substance registered dossier
Elanco Animal Health GmbH	Alfred Nobel Straße 50 40789 Monheim Germany	Germany	Active	(3S,6R,9S,12R,15S,18R,21S,24R)-6,18-dibenzyl-3,9,15,21-tetraisobutyl-4,10,12,16,22,24-hexamethyl-1,7,13,19-tetraoxa-4,10,16,22-tetraazacyclo-tetracosane-2,5,8,11,14,17,20,23-octaone	444-350-6	133413-70-4	-	View substance registered dossier
Bayer AG	Kaiser-Wilhelm-Allee 1 51373 Leverkusen Germany	Germany	Active	(3S,6R,9S,12R,15S,18R,21S,24R)-6,18-dibenzyl-3,9,15,21-tetraisobutyl-4,10,12,16,22,24-hexamethyl-1,7,13,19-tetraoxa-4,10,16,22-tetraazacyclo-tetracosane-2,5,8,11,14,17,20,23-octaone	444-350-6	133413-70-4	2010; 2018	View substance registered dossier
Corteva Agriscience Belgium B.V.	Rue Montoyer 25, 1000 Brussels Belgium	Belgium	Active	(3S,6S,7R,8R)-8-Benzyl-3-{[(3-hydroxy-4-methoxypyridin-2-yl)carbonyl]amino}-6-methyl-4,9-dioxo-1,5-dioxonan-7-yl 2-methylpropanoate	844-009-5	167173-85-5	-	View substance registered dossier
Purac Bioquímica S.A.U.	Gran Vial 19-25 08160 Montmeló (Barcelona) Spain	Spain	Active	(3S-cis)-3,6-dimethyl-1,4-dioxane-2,5-dione	224-832-0	4511-42-6	-	View substance registered dossier
Purac Biochem bv	Arkelsedijk 46 4206AC Gorinchem Netherlands	Netherlands	Active	(3S-cis)-3,6-dimethyl-1,4-dioxane-2,5-dione	224-832-0	4511-42-6	2011; 2015; 2022	View substance registered dossier
TotalEnergies Corbion BV	Stadhuisplein 70 4203 NS Gorinchem Netherlands	Netherlands	Active	(3S-cis)-3,6-dimethyl-1,4-dioxane-2,5-dione	224-832-0	4511-42-6	-	View substance registered dossier
Evonik Operations GmbH	Rellinghauser Straße 1-11 45128 Essen Germany	Germany	Active	(3S-cis)-3,6-dimethyl-1,4-dioxane-2,5-dione	224-832-0	4511-42-6	-	View substance registered dossier
Futerro SA	Rue du Renouveau 7760 Escannafles Belgium	Belgium	Active	(3S-cis)-3,6-dimethyl-1,4-dioxane-2,5-dione	224-832-0	4511-42-6	-	View substance registered dossier
Santrol Europe ApS	Aagade 103 Pjedsted 7000 Fredericia Denmark	Denmark	Cease Manufacture	(3S-cis)-3,6-dimethyl-1,4-dioxane-2,5-dione	224-832-0	4511-42-6	2016	View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant Irish competent national authority.	-	-	Active	(3S-trans)-phenyl-3-[(1,3-benzodioxol-5-yloxy)methyl]-4-(4-fluorophenyl)-1-piperidinecarboxylate	430-510-2	-	-	View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant UK competent national authority.	-	-	Active	(3S-trans)-phenyl-3-[(1,3-benzodioxol-5-yloxy)methyl]-4-(4-fluorophenyl)-1-piperidinecarboxylate	430-510-2	-	-	View substance registered dossier
IFF Benicarlo, S.L.	Avda. Felipe Klein 2 12580 Benicarlo Castellon Spain	Spain	Active	(3Z)-hex-3-en-1-yl 2-methylprop-2-en-1-yl ether	439-790-0	292605-05-1	2013	View substance registered dossier
IFF Benicarlo, S.L.	Avda. Felipe Klein 2 12580 Benicarlo Castellon Spain	Spain	Active	(3Z)-hex-3-en-1-yl cyclopropanecarboxylate	425-200-9	188570-78-7	2012	View substance registered dossier
-	-	-	-	(3Z)-hex-3-en-1-yl cyclopropanecarboxylate	425-200-9	188570-78-7	-	View substance registered dossier
Farmabios Spa	Via Pavia, 1 27027 Gropello Cairoli PV Italy	Italy	Active	(3α,5β,7β)-3,7-Dihydroxy-24-norcholane-23-nitrile	828-107-5	118316-12-4	-	View substance registered dossier
OLON Spa	Strada Rivoltana Km 6/7 20053 RODANO Milano Italy	Italy	Active	(3β)-17-(1,1,1-trifluoromethanesulfonate)-Androsta-5,16-diene-3,17-diol, 3-(2,2,2-trifluoroacetate)	840-627-4	1802323-89-2	-	View substance registered dossier
OLON Spa	Strada Rivoltana Km 6/7 20053 RODANO Milano Italy	Italy	Active	(3β)-3-[(2,2,2-trifluoroacetyl)oxy]-Androst-5-en-17-one	840-626-9	3798-17-2	-	View substance registered dossier
Indena S.p.A.	Viale Ortles, 12 20139 Milan Italy	Italy	Active	(3β,20β)-3-acetoxy-11-oxoolean-12-en-29-oic acid	228-475-1	6277-14-1	2019	View substance registered dossier
DSM Nutritional Products France SAS	1 boulevard d'Alsace F-68128 Village-Neuf France	France	Active	(3β,5Z,7E)-9,10-secocholesta-5,7,10(19)-trien-3-yl butyrate	250-567-5	31316-20-8	2022	View substance registered dossier
Merck KGaA	Frankfurter Strasse 250 64293 Darmstadt Germany	Germany	Active	(4'-methyl-3-fluoro[1,1'-biphenyl]-4-yl)-boronic acid	813-651-8	1698890-39-9	2022	View substance registered dossier
QUIMICA SINTETICA, S.A.	C/ Dulcinea, s/n 28805 Alcalá de Henares Madrid Spain	Spain	Active	(4,5-dibromo-1H-pyrrol-2-yl)(phenyl)methanone	700-338-5	50372-61-7	2016	View substance registered dossier
UNION QUIMICO FARMACÉUTICA S.A.	Mallorca 262 08008 Barcelona Barcelona Spain	Spain	Active	(4,5-dibromo-1H-pyrrol-2-yl)(phenyl)methanone	700-338-5	50372-61-7	2016	View substance registered dossier
ELKEM SILICONES FRANCE S.A.S.	Immeuble DANICA 21, Avenue Georges Pompidou 69003 Lyon France	France	Active	(4-(1-methylethyl)phenyl)-(4-methylphenyl)iodonium tetrakis(pentafluorophenyl)borate (1-)	422-960-3	178233-72-2	2023	View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant UK competent national authority.	-	-	Active	(4-(1-methylethyl)phenyl)-(4-methylphenyl)iodonium tetrakis(pentafluorophenyl)borate (1-)	422-960-3	178233-72-2	-	View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant French competent national authority.	-	-	Active	(4-(1-methylethyl)phenyl)-(4-methylphenyl)iodonium tetrakis(pentafluorophenyl)borate (1-)	422-960-3	178233-72-2	-	View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant UK competent national authority.	-	-	Active	(4-(4-(4-dimethylaminobenzyliden-1-yl)-3-methyl-5-oxo-2-pyrazolin-1-yl)benzoic acid	410-430-4	117573-89-4	-	View substance registered dossier
CU Chemie Uetikon GmbH	Raiffeisenstrasse 4 77933 Lahr Baden-Württemberg Germany	Germany	Active	(4-(4-amino-6,7-dimethoxyquinazolin-2-yl)piperazin-1-yl)(tetrahydrofuran-2-yl)methanone	613-265-8	63590-64-7	2018	View substance registered dossier
Global Product Compliance (Europe) AB	IDEON, Beta 5, Scheelevägen 17 22363 Lund Sweden	Sweden	Cease Manufacture	(4-(4-aminophenyl)(4-iminocyclohexa-2,5-dienylidene)methyl)-2-methylaniline hydrochloride	211-189-6	632-99-5	2023	View substance registered dossier
AllessaProduktion GmbH	Alt-Fechenheim 34 60386 Frankfurt am Main Germany	Germany	Active	(4-(5-Oxo-4,5-dihydro-1,2,4-oxadiazol-3-yl)-phenylamino)-acetic acid ethyl ester	927-587-4	872728-83-1	2016	View substance registered dossier
Bidachem S.p.A.	S.S. 11 Padana Superiore No. 8 24040 Fornovo San Giovanni BG Italy	Italy	Cease Manufacture	(4-(5-Oxo-4,5-dihydro-1,2,4-oxadiazol-3-yl)-phenylamino)-acetic acid ethyl ester	927-587-4	872728-83-1	2023	View substance registered dossier
Boehringer Ingelheim Pharma GmbH & Co. KG	Binger Strasse 173 55216 Ingelheim am Rhein Germany	Germany	Active	(4-(5-Oxo-4,5-dihydro-1,2,4-oxadiazole-3-yl)phenylamino)acetic acid	460-450-2	872728-82-0	2012; 2014; 2016	View substance registered dossier
F.I.S. Fabbrica Italiana Sintetici S.p.a.	Viale Milano, 26 36075 Montecchio Maggiore (VI) Veneto Italy	Italy	Active	(4-(5-Oxo-4,5-dihydro-1,2,4-oxadiazole-3-yl)phenylamino)acetic acid	460-450-2	872728-82-0	-	View substance registered dossier
Bidachem S.p.A.	S.S. 11 Padana Superiore No. 8 24040 Fornovo San Giovanni BG Italy	Italy	Active	(4-(5-Oxo-4,5-dihydro-1,2,4-oxadiazole-3-yl)phenylamino)acetic acid	460-450-2	872728-82-0	2013; 2016	View substance registered dossier
AllessaProduktion GmbH	Alt-Fechenheim 34 60386 Frankfurt am Main Germany	Germany	Active	(4-(5-Oxo-4,5-dihydro-1,2,4-oxadiazole-3-yl)phenylamino)acetic acid	460-450-2	872728-82-0	2012; 2019	View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant UK competent national authority.	-	-	Active	(4-(6-diethylamino-2-methylpyridin-3-yl)imino-4,5-dihydro-3-methyl-1-(4-methylphenyl)-1H-pyrazol-5-one	427-070-9	-	-	View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant Belgian competent national authority.	-	-	Active	(4-6) PEPTIDE	427-550-8	-	-	View substance registered dossier
United Initiators GmbH	Dr. Gustav-Adolph-Str. 3 D-82049 Pullach Bavaria Germany	Germany	Cease Manufacture	(4-acetamido-2,2,6,6-tetramethyl-1-piperidinyl)oxidanyl;N-(2,2,6,6-tetramethyl-1-oxylpiperidin-4-yl)acetamide	423-840-3	14691-89-5	2022	View substance registered dossier
Evonik Operations GmbH	Rellinghauser Straße 1-11 45128 Essen Germany	Germany	Active	(4-acetamido-2,2,6,6-tetramethyl-1-piperidinyl)oxidanyl;N-(2,2,6,6-tetramethyl-1-oxylpiperidin-4-yl)acetamide	423-840-3	14691-89-5	2012; 2022	View substance registered dossier
[Confidential]	-	-	-	(4-acetamido-2,2,6,6-tetramethyl-1-piperidinyl)oxidanyl;N-(2,2,6,6-tetramethyl-1-oxylpiperidin-4-yl)acetamide	423-840-3	14691-89-5	-	View substance registered dossier
MSD International GmbH (Ballydine Branch)	Ballydine - Kilsheelan 0 Clonmel Ireland	Ireland	Active	(4-amino-1-hydroxy-1-phosphonobutyl)phosphonic acid;hydrate	680-378-7	138624-11-0	-	View substance registered dossier
Menadiona SL	Pol Ind Mas Puigvert, Ctra Nacional II Km 680, 5 08389 Palafolls Barcelona Spain	Spain	Active	(4-amino-2-chloro-5-methylphenyl)(4-chlorophenyl)acetonitrile	262-792-6	61437-85-2	-	View substance registered dossier
Globalquimia, S.L.U.	Avenida Diagonal, 519, 1º 1ª 08029 Barcelona Spain Spain	Spain	Active	(4-amino-2-chloro-5-methylphenyl)(4-chlorophenyl)acetonitrile	262-792-6	61437-85-2	-	View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant Irish competent national authority.	-	-	Active	(4-aminophenyl)-N-methylmethylenesulfonamide hydrochloride	406-010-5	88918-84-7	-	View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant UK competent national authority.	-	-	Active	(4-aminophenyl)-N-methylmethylenesulfonamide hydrochloride	406-010-5	88918-84-7	-	View substance registered dossier
Evonik Operations GmbH	Rellinghauser Straße 1-11 45128 Essen Germany	Germany	Cease Manufacture	(4-benzylpiperazin-1-yl)(cyclopropyl)methanone hydrochloride	816-907-7	1294454-93-5	2021	View substance registered dossier
Merck KGaA	Frankfurter Strasse 250 64293 Darmstadt Germany	Germany	Active	(4-butoxy-2,3-difluorophenyl)boronic acid	692-793-0	156487-12-6	2022	View substance registered dossier
Evonik Operations GmbH	Rellinghauser Straße 1-11 45128 Essen Germany	Germany	Active	(4-carboxybutyl)triphenylphosphonium bromide	241-782-5	17814-85-6	2022	View substance registered dossier
Derivados Quimicos SAU	Strada Rivoltana km6/7 20053 Rodano (Milano) Lombardia Spain	Spain	Cease Manufacture	(4-Chloro-2-fluoro-phenyl)-acetonitrile	642-783-7	75279-53-7	2020	View substance registered dossier
F.I.S. Fabbrica Italiana Sintetici S.p.a.	Viale Milano, 26 36075 Montecchio Maggiore (VI) Veneto Italy	Italy	Active	(4-Chloro-3-(4-ethoxybenzyl)phenyl)((3aS,5R,6S,6aS)-6-hydroxy-2,2-dimethyltetrahydrofuro[2,3-d][1,3]dioxol-5-yl)methanone	695-300-7	1103738-30-2	-	View substance registered dossier
sanofi chimie	82 avenue Raspail 94250 Gentilly France	France	Active	(4-Chloro-3-(4-ethoxybenzyl)phenyl)((3aS,5R,6S,6aS)-6-hydroxy-2,2-dimethyltetrahydrofuro[2,3-d][1,3]dioxol-5-yl)methanone	695-300-7	1103738-30-2	2020	View substance registered dossier
Derivados Químicos S.A.	Camino de Pliego, 150 30820 Alcantarilla Murcia Spain	Spain	Active	(4-chlorophenyl)-(2,2,8-trimethyl-4H-[1,3]dioxino[4,5-c]pyridin-5-yl)methanol	814-124-5	133545-64-9	-	View substance registered dossier
Fine Organics Limited	Seal Sands TS2 1UB Middlesbrough Teesside United Kingdom	United Kingdom	No longer Valid	(4-chlorophenyl)hydrazine	214-029-3	1073-69-4	2018	View substance registered dossier
BASF SE	Carl-Bosch-Str. 38 67056 Ludwigshafen am Rhein Rheinland-Pfalz Germany	Germany	Active	(4-chlorophenyl)hydrazine	214-029-3	1073-69-4	2010	View substance registered dossier
Bidachem S.p.A.	S.S. 11 Padana Superiore No. 8 24040 Fornovo San Giovanni BG Italy	Italy	Cease Manufacture	(4-cyclopropyl-6-methyl-pyrimidin-5-yl)boronic acid	826-639-2	1817776-86-5	2022	View substance registered dossier
Boehringer Ingelheim Pharma GmbH & Co. KG	Binger Strasse 173 55216 Ingelheim am Rhein Germany	Germany	Cease Manufacture	(4-cyclopropyl-6-methyl-pyrimidin-5-yl)boronic acid	826-639-2	1817776-86-5	2022	View substance registered dossier
INTEROR	49, rue d'Ostende F-62100 CALAIS France	France	Cease Manufacture	(4-ethoxyphenyl)(3-(4-fluoro-3-phenoxyphenyl)propyl)dimethylsilane	405-020-7	105024-66-6	2022	View substance registered dossier
Bayer AG	Kaiser-Wilhelm-Allee 1 51373 Leverkusen Germany	Germany	Cease Manufacture	(4-ethoxyphenyl)(3-(4-fluoro-3-phenoxyphenyl)propyl)dimethylsilane	405-020-7	105024-66-6	2010	View substance registered dossier
Fine Organics Limited	Seal Sands TS2 1UB Middlesbrough Teesside United Kingdom	United Kingdom	No longer Valid	(4-hydrazinophenyl)-N-methylmethanesulfonamide hydrochloride	406-090-1	81880-96-8	2021	View substance registered dossier
Synthesia, a.s.	Semtín103 53002 Pardubice Czech Republic	Czech Republic	Active	(4-methoxybiphenyl-3-yl)hydrazine hydrochloride	924-885-6	-	-	View substance registered dossier
-	-	-	-	(4-Methoxyphenyl)diphenylsulfoniumnonaflate	435-570-3	-	-	View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant UK competent national authority.	-	-	Active	(4-Methoxyphenyl)diphenylsulfoniumnonaflate	435-570-3	-	-	View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant UK competent national authority.	-	-	No longer Valid	(4-methylphenyl)mesitylene sulfonate	407-530-5	67811-06-7	2022	View substance registered dossier
MINAKEM Beuvry Production SAS	145, Chemin des Lilas 59310 Beuvry-la-Forêt France	France	Active	(4-nitrophenyl)methanesulfonyl chloride	609-806-2	4025-75-6	-	View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant Irish competent national authority.	-	-	Active	(4-nitrophenyl)methyl [6R,(6α,7β)]-[3-hydroxy-5,8-dioxo-7-(phenoxyacetylamino)-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate]	411-820-7	-	-	View substance registered dossier
BASF Lampertheim GmbH	Chemiestrasse 22 68619 Lampertheim Germany	Germany	Active	(4-nonylphenoxy)acetic acid	221-486-2	3115-49-9	2014	View substance registered dossier
BASF SE	Carl-Bosch-Str. 38 67056 Ludwigshafen am Rhein Rheinland-Pfalz Germany	Germany	Active	(4-nonylphenoxy)acetic acid	221-486-2	3115-49-9	-	View substance registered dossier
Colors & Effects France S.A.S.	Rue de la Chapelle 28 68330 Huningue France	France	Cease Manufacture	(4-nonylphenoxy)acetic acid	221-486-2	3115-49-9	2015	View substance registered dossier
Corden Pharma Latina S.p.A.	Via Murillo, 7 IT04013 Sermoneta (LT) Lazio Italy	Italy	Cease Manufacture	(4-phenylbutyl)phosphinic acid	420-450-5	86552-32-1	2017	View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant Irish competent national authority.	-	-	Active	(4-phenylbutyl)phosphinic acid	420-450-5	86552-32-1	-	View substance registered dossier
INTEROR	49, rue d'Ostende F-62100 CALAIS France	France	Active	(4-pyridylmethyl)amine	223-092-6	3731-53-1	-	View substance registered dossier
Fine and Performance Chemicals Ltd	Skutterskelfe TS15 0JR Hutton Rudby North Yorkshire United Kingdom	United Kingdom	No longer Valid	(4-pyridylthio)acetyl chloride hydrochloride	248-348-4	27230-51-9	2021	View substance registered dossier
Corden Pharma Latina S.p.A.	Via Murillo, 7 IT04013 Sermoneta (LT) Lazio Italy	Italy	Active	(4-pyridylthio)acetyl chloride hydrochloride	248-348-4	27230-51-9	-	View substance registered dossier
ChemLeader 11 Fine & Performance Chemicals Ltd	Długosza 67 43-188 Orzesze Poland	Poland	Active	(4-pyridylthio)acetyl chloride hydrochloride	248-348-4	27230-51-9	2021	View substance registered dossier
CHEMSAFE srl on behalf of AZO INTERNATIONAL CHEMICAL ltd	Via Ribes, 5 10010 Colleretto Giacosa TO Italy	Italy	Active	(4-pyridylthio)acetyl chloride hydrochloride	248-348-4	27230-51-9	-	View substance registered dossier
Siegfried PharmaChemikalien Minden GmbH	Karlstr. 15-39, 42-44 32423 Minden Nordrhein-Westphalen Germany	Germany	Active	(4-tert-butyl-2,6-dimethylphenyl)acetonitrile	284-183-4	84803-57-6	-	View substance registered dossier
FujiFilm Manufacturing Europe BV	Oudenstaart 1 5047 TK Tilburg Netherlands	Netherlands	Active	(4-vinylphenyl)methyl-2-[(1Z)-1-aza-3-methyl-2-(4-methylthiophenyl)-3-morpholin-4-ylbut-1-enyloxy]acetate	453-050-4	-	2011	View substance registered dossier
Janssen Pharmaceutica N.V.	Turnhoutseweg 30 2340 Beerse Belgium	Belgium	Active	(4aR, 8aR)-1-bromo-4a,5,9,10,11,12-hexahydro-3-methoxy-6H-benzofuro[3a,3,2-ef] [2]benzazepin-6-one hydrochloride (1:1)	700-867-1	-	2020	View substance registered dossier
Janssen Pharmaceutica N.V.	Turnhoutseweg 30 2340 Beerse Belgium	Belgium	Cease Manufacture	(4aR,8aR)-4a,5,9,10,11,12-hexahydro-3-methoxy-11-methyl-6H-benzofuro[3a,3,2-ef][2]benzazepin-6-one	428-690-2	1668-86-6	2019	View substance registered dossier
NEWCHEM S.P.A.	VIA EDMONDO DE AMICIS 47 20123 MILANO ITALY Italy	Italy	Active	(4aR,4bS,5S,6aS,6bS,9aR,10aS,10bS)-6b-Acetyl-5-hydroxy-4a,6a,8-trimethyl-4a,4b,5,6,6a,6b,9a,10,10a,10b,11,12-dodecahydro-2H-naphtho[2',1':4,5]indeno[1,2-d][1,3]oxazol-2-one	680-670-4	13649-88-2	-	View substance registered dossier
Gedeon Richter Plc.	Gyomroi ut 19-21 1103 Budapest Hungary	Hungary	Active	(4aR,4bS,6aS,7aS,8aS,8bR,8cR)-2-methoxy-4a,6a-dimethyl-4,4a,4b,5,6,6a,7a,8,8a,8b,8c,9-dodecahydrocyclopropa[4,5]cyclopenta[1,2-a]phenanthren-7(3H)-one	607-934-3	26441-40-7	2020	View substance registered dossier
Gedeon Richter Plc.	Gyomroi ut 19-21 1103 Budapest Hungary	Hungary	Active	(4aR,4bS,6aS,7S,7aS,8aS,8bR,8cR)-7-[2-(1,3-dioxolan-2-yl)ethyl]-2-methoxy-4a,6a-dimethyl-3,4,4a,4b,5,6,6a,7,7a,8,8a,8b,8c,9-tetradecahydrocyclopropa[4,5]cyclopenta[1,2-a]phenanthren-7-ol	618-226-9	889652-22-6	2020	View substance registered dossier

Showing 701 - 800 of 26,862 results.

In this table, you will find all public data submitted to ECHA in REACH registration dossiers by substance manufacturers, importers, or their representatives, as laid out by the REACH Regulation (see Understanding REACH regulation).

ECHA makes available this information as REACH registered substance factsheets, which contain the full set of non-confidential information from related registration dossiers for a substance. Depending on the number of registrations that have been made for a substance, one factsheet can thus represent data from anything between hundreds of registration dossiers in a joint submission, to data from just one registration dossier.

As noted in the Legal Notice of the ECHA website, ECHA does not give any guarantees or warranties regarding the quality and correctness of the published information. The information in the portal is published ‘as provided’ by industry, and its accuracy has not been verified by ECHA. ECHA is also not in a position to intervene with, edit or correct the published data; this can only be done by the registrant responsible for its submission. Please also note that the information may be protected and its use may require prior permission from its owner (see the ECHA website Legal Notice more details).

In the portal results table are presented:

Public substance identity – the best available non-confidential substance name, EC, and CAS numbers.
Registration status – indicating the calculated registration status for the whole factsheet: Active – is being manufactured or imported to the EEA by one or more registrants; Cease Manufacture - is no longer being manufactured or imported above 1 tone per calendar year. All registrants of the substance have reported a cease of manufacture or import; or No longer valid - no longer considered registered under REACH and not currently allowed to be manufactured or imported to the EEA, until the substance is registered again.
Registration type – indicating whether a given factsheet contains data from a REACH full registration, REACH intermediate registration, or only a limited set of data inherited from a NONS notification.
Submission type – indicating whether the data in a given factsheet was submitted jointly or individually.
Total tonnage band – calculated per factsheet from all contributing registrations, based on the estimated quantity of the substance placed on the market. Data is excluded from dossiers where the tonnage is claimed confidential, from Intermediate registration dossiers, and from NONs which have not been updated.
Last updated – indicating the date on which this registered substance factsheet was last modified with new or updated data, based on an industry submission.
Link to the full factsheet.

Chemical Property Data Search

A subset of the key chemical properties (physico-chemical, environmental fate, ecotoxicological and toxicological data) of registered substances can be searched and accessed via the OECD eChemPortal.

RELATED INFORMATION

Welcome to the REACH Registered Substance Factsheets

Here you will find details from REACH registrations submitted to ECHA. Registrations under REACH can be submitted either jointly – where a group of legal entities pool their data – or individually. The set of details from each published joint or individual submission is presented as a row in the results table. For each row there is also an ‘eye’ icon leading to the detailed factsheet which contains the entire public dataset, following the IUCLID format.

Note that there can be more than one joint or individual submission for the same substance, thus there can be cases where one substance is covered by many REACH registered substance factsheets.

Note too, that as mentioned in the Legal Notice of the ECHA website, ECHA does not give any guarantees or warranties regarding the quality and correctness of the published information. The information in the portal is published ‘as provided’ by industry, and its accuracy has not been verified by ECHA. ECHA is also not in a position to intervene with, edit or correct the published data; this can only be done by the registrant responsible for its submission.

Finally, please note that the information may be protected and its use may require prior permission from its owner (see the ECHA website Legal Notice more details).

All substances table

The “All substances” table gives an overview of all the REACH registered substance factsheets on file at ECHA. Since this covers all data ever submitted since the entry into force of the REACH Regulation, there are some substances which are no longer considered registered under REACH in the EU / EEA. These can be for example substances that were registered only in the UK; since Brexit they are no longer registered in the EU / EEA.

The following columns are presented in the “All substances” table:

Public substance identity – the best available non-confidential substance name, EC, and CAS numbers.
Registration status – indicating the calculated registration status for the whole factsheet: Active – is being manufactured or imported to the EEA by one or more registrants; Cease Manufacture - is no longer being manufactured or imported above 1 tone per calendar year. All registrants of the substance have reported a cease of manufacture or import; or No longer valid - no longer considered registered under REACH and not currently allowed to be manufactured or imported to the EEA, until the substance is registered again.
Registration type – indicating whether a given factsheet contains data from a REACH full registration, REACH intermediate registration, or only a limited set of data inherited from a NONS notification.
Submission type – indicating whether the data in a given factsheet was submitted jointly or individually.
Total tonnage band – calculated per factsheet from all contributing registrations, based on the estimated quantity of the substance placed on the market. Data is excluded from dossiers where the tonnage is claimed confidential, from Intermediate registration dossiers, and from NONs which have not been updated.
Last updated – indicating the date on which this registered substance factsheet was last modified with new or updated data, based on an industry submission.
‘Eye’ icon linking to the full factsheet.

Searching

The search for REACH registered substance factsheets is divided into logically separated blocks of related search filters. Note that the search works so that if you provide filters in different blocks, then the results returned must match the filters in block 1 AND those in block 2 etc. Searches are conducted on all the public data included in all published REACH registrations.

Substance identity

In this block you can search by substance identifiers, under filters for Name, EC / List number, and CAS number. Full or partial identifiers can be used. And under the Name filter you can search by any substance name of any kind from any source. Other numerical identifiers such as Harmonised C&L Index number, or PIC CN code can also optionally be used.

Administrative data

In this block you can search by administrative information relating to REACH registered substance factsheets:

Registration type – picklist of Full, Intermediate, NONS
Registration status – picklist of Active, Cease Manufacture, No longer valid
Submission type – Individual or Joint
Country in which registered – picklist of current and former EU / EEA member states from which REACH registrations were received
First published date – the date when a REACH registration factsheet was first published
Last update date – the last date when any registrant / supplier submission contributing to a given REACH registration factsheet was submitted
Last update year – the year in which any registrant / supplier last made an update submission included in a given REACH registration factsheet
Registrant / supplier name – where available and not claimed confidential
Registration number – where available and not claimed confidential
Registrant address – where available and not claimed confidential

Substance data

In this block you can search by substance related data from REACH registered substance factsheets:

Tonnage band – picklist of Tonnage range, Tonnage Confidential, Intermediate use only
Selected total tonnage band range – available only if Tonnage range is selected, and allows to filter REACH registered substance factsheets within any selected min and max value
Substance has nanoform – picklist of Yes, No
PBT assessment outcome – picklist of all possible PBT assessment outcomes
CSA performed – picklist of Yes, No

Use and exposure

In this block you can search by elements relating to how use and exposure are encoded in REACH registrations.

Under the Life cycle option you can select one or more life cycle stages. The search results returned will include only factsheets containing uses reported under the selected life cycle stages.

Under the Category option there are modal popups for each of the use descriptor categories – Product, Sector of use, Process, Environmental release, and Article categories. In each of these are multi select picklists for all the related descriptor codes. The search results returned will include only factsheets containing uses which include the selected descriptor codes.

Note that the Life cycle and Category options work together, so that if a life cycle stage and Category options are both selected the search results will include factsheets containing specific uses in the selected life cycle stage, and where the use includes the selected descriptor codes.

With the search operator option you can select to refine how the search works. AND refines results and returns only those factsheets where ALL the search filter criteria are met. OR broadens the results and returns factsheets where ANY of the selected search filter criteria are met.

The factsheets

There is always a detailed factsheet per joint or individual submission, and it is generated based primarily on the IUCLID format.

The factsheet header begins with the identity of the substance in question, to which the factsheet is linked. The substance identity should always be aligned with that shown in the related substance Infocard. Note that since the Infocard refreshes daily, whereas the factsheet sometimes refreshes on a slower pace, sometimes the data may be out of alignment. In such cases it will always realign as quickly as possible.

The substance identification is enriched with the data provided in the relevant IUCLID section of the primary submitted dossier – either the joint submission lead, or the single individual submission.

In this section are also provided the type of substance, all other identifiers such as trade names, common names, other names etc, as well as all distinct submitted compositions for the substance.

Next is a page covering administrative type information from the data submitted, including:

Registration details, on the total tonnage band informed to ECHA, the registration type, first published and last updated dates, and whether a chemical safety assessment has been performed.

Registrant / supplier details, giving the identity and status of registrants / suppliers, except where the identity has been claimed confidential.

Registration numbers, giving again the identity and status of registration numbers, except where claimed confidential.

Contact persons responsible for the SDS, giving the non-confidential SDS contacts provided to ECHA.

The remainder of the factsheet faithfully follows the IUCLID structure, covering the C&L and PBT, Manufacture, use, and exposure, Physical and chemical properties, Environmental fate and pathways, Ecotoxicological information, Toxicological information, Analytical methods (if available), Guidance on safe use, Assessment reports, and Reference substances.

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