Registered substances

Registered substances

Registered substances

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REACH - Registration, Evaluation, Authorisation and Restriction of Chemicals Regulation

Registered Substances Factsheets

Substances which have been registered and can be placed on the EEA market by those companies with a valid registration



No results were found
Details
(1S)-1-Phenylethanaminium (2S)-2-(2-fluorobiphenyl-4-yl)propanoate
942-079-2 - No longer Valid Intermediate Individual No longer valid 05-03-2020 View substance registered dossier
(2,3,5,6-tetrafluoro-4-methylphenyl)methanol
453-520-9 - No longer Valid NONS Individual No longer valid 08-12-2020 View substance registered dossier
(2,5-dimethyl-2,3-dihydro-1H-inden-2-yl)methanol
437-760-1 - Active Full Joint ≥ 10 to < 100 tonnes 12-12-2022 View substance registered dossier
(2,5-dimethyl-2,3-dihydro-1H-inden-2-yl)methanol
437-760-1 - Active NONS Individual Tonnage data confidential 10-11-2008 View substance registered dossier
(2-((2 S,3 S)-2-(( S)-3-( tert-butoxy)-2-(( S)-2-(( S)-4-( tert-butoxy)-2-(( S)-3-( tert-butoxy)-2-((2 S,3 R)-3-( tert-butoxy)-2-(( S)-2-((2 S,3 R)-3-( tert-butoxy)-2-(2-(( S)-5-( tert-butoxy)-2-(2-(( S)-3-(4-( tert-butoxy)phenyl)-2-(( tert-butoxycarbonyl)amino)propanamido)-2-methylpropanamido)-5-oxopentanamido)acetamido)butanamido)-3-phenylpropanamido)butanamido)propanamido)-4-oxobutanamido)-3-(4-( tert-butoxy)phenyl)propanamido)propanamido)-3-methylpentanamido)-2-methylpropanoyl)- L-leucine
955-183-8 - Active Intermediate Joint Intermediate use only 21-12-2021 View substance registered dossier
(2-(1-Chlorocyclopropyl)-3-(2-chlorophenyl)propyl)hydrazine
449-460-8 - Active NONS Joint Tonnage data confidential 30-01-2023 View substance registered dossier
(2-(1-isopropyl-1H-pyrazol-5-yl)pyrid-3-yl)methanol hydrochloride (1:1)
941-991-8 - Active Intermediate Joint Intermediate use only 11-04-2018 View substance registered dossier
(2-(2-hydroxyethoxy)ethyl) oxo(phenyl)acetate;reaction mass of: 2-(2-((oxo(phenyl)acetyl)oxy)ethoxy)ethyl oxo(phenyl)acetate
442-300-8 - Active Full Joint ≥ 100 to < 1 000 tonnes 24-11-2020 View substance registered dossier
(2-butoxyethoxy)acetic acid
451-650-0 - Active NONS Individual Tonnage data confidential 10-12-2010 View substance registered dossier
(2-formamido-1,3-thiazol-4-yl)(oxo)acetic acid
426-680-2 - Active Intermediate Individual Intermediate use only 28-11-2011 View substance registered dossier
(2-formamido-1,3-thiazol-4-yl)(oxo)acetic acid
426-680-2 - Active NONS Individual Tonnage data confidential 09-12-2013 View substance registered dossier
(2E)-N-(5-Cyano-4-{(E)-[(dimethylamino)methylene]amino}-2-methoxyphenyl)-4-(piperidin-1-yl)but-2-enamide
939-152-6 - Active Intermediate Joint Intermediate use only 27-09-2022 View substance registered dossier
(2R)-2-(2,5-difluorophenyl)pyrrolidine, (2R,3R)-2,3-bis[(4-methoxybenzoyl)oxy]butanedioic acid
951-764-5 - Active Intermediate Individual Intermediate use only 15-01-2020 View substance registered dossier
(2R)-N-(2,6-Dimethylphenyl)-1-propylpiperidine-2-carboxamide - (2R,3R)-2,3-dihydroxysuccinic acid - propan-2-ol (2:1:1)
947-841-8 - Active Intermediate Individual Intermediate use only 16-05-2018 View substance registered dossier
(2R*,3S*)-2-(2,4-difluorophenyl)-3-(5-fluoro-4-pyrimidinyl)-1-(1H-1,2,4-triazol-1-yl)butan-2-ol (1R)-10-camphorsulfonate
UK-103,449-BV
427-100-0 - No longer Valid NONS Individual No longer valid 10-11-2008 View substance registered dossier
(2R,3R)-2,3-Dihydroxybutanedioic acid-(2S)-N-(2,6-dimethylphenyl)-1-propylpiperidine-2-carboxamide (1/1)
947-840-2 - Active Intermediate Individual Intermediate use only 16-05-2018 View substance registered dossier
(2R,3R,11bR)-3-Isobutyl-9,10-dimethoxy-1,3,4,6,7,11b-hexahydro-2H-pyrido[2,1-a]isoquinolin-2-ol [(1S,4R)-7,7-Dimethyl-2-oxobicyclo[2.2.1]hept-1-yl]methanesulfonic acid
948-743-8 - Active Intermediate Joint Intermediate use only 04-10-2018 View substance registered dossier
(2S)-2-[[(2S)-6-[[2-[2-[2-[[2-[2-[2-[[(4S)-5-tert-butoxy-4-[(20-tert-butoxy-20-oxo-icosanoyl)amino]-5-oxo-pentanoyl]amino]ethoxy]ethoxy]acetyl]amino]ethoxy]ethoxy]acetyl]amino]-2-[[(2S)-2-[[(2S)-2-[[(2S,3S)-2-[[(2S)-6-(tert-butoxycarbonylamino)-2-[[(2S)-4-tert-butoxy-2-(9H-fluoren-9-ylmethoxycarbonylamino)-4-oxo-butanoyl]amino]hexanoyl]amino]-3-methyl-pentanoyl]amino]propanoyl]amino]-5-oxo-5-(tritylamino)pentanoyl]amino]hexanoyl]amino]propanoic acid
954-943-6 - Active Intermediate Individual Intermediate use only 10-10-2022 View substance registered dossier
(2S)-2-hydrazinyl-3-[4-hydroxy-3-(substituted)phenyl]-2-alkylpropanoic acid
- - Active Intermediate Joint Intermediate use only 04-06-2021 View substance registered dossier
(2S)-2-hydrazinyl-3-[4-hyrdoxy-3-(substituted)phenyl]-2-alkylpropanoic acid — tert-alkylamine (1/1)
- - Active Intermediate Joint Intermediate use only 04-06-2021 View substance registered dossier
No results were found
Registrant/Supplier Address Country Registration Status Name EC / List no. CAS no. Last update year Details
Aesica Pharmaceuticals Limited Windmill Industrial Estate Shotton Lane NE23 3JL Cramlington Northumberland United Kingdom United Kingdom No longer Valid (1S)-1-Phenylethanaminium (2S)-2-(2-fluorobiphenyl-4-yl)propanoate 942-079-2 - 2021 View substance registered dossier
Syngenta Ltd Jealott’s Hill International Research Centre RG42 6EY Bracknell Berkshire United Kingdom United Kingdom No longer Valid (2,3,5,6-tetrafluoro-4-methylphenyl)methanol 453-520-9 - 2021 View substance registered dossier
LES DERIVES RESINIQUES ET TERPENIQUES 30 rue Gambetta B.P. 206 40105 Dax Cedex France France Cease Manufacture (2,5-dimethyl-2,3-dihydro-1H-inden-2-yl)methanol 437-760-1 - 2021 View substance registered dossier
FIRMENICH GRASSE SAS OR 4 Parc Industriel Les Bois de Grasse 06130 Grasse France France Active (2,5-dimethyl-2,3-dihydro-1H-inden-2-yl)methanol 437-760-1 - - View substance registered dossier
FIRMENICH GRASSE SAS OR 1 Parc Industriel Les Bois de Grasse 06130 Grasse France France Active (2,5-dimethyl-2,3-dihydro-1H-inden-2-yl)methanol 437-760-1 - 2011; 2019 View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant UK competent national authority. - - Active (2,5-dimethyl-2,3-dihydro-1H-inden-2-yl)methanol 437-760-1 - - View substance registered dossier
[Confidential] - - - (2-((2 S,3 S)-2-(( S)-3-( tert-butoxy)-2-(( S)-2-(( S)-4-( tert-butoxy)-2-(( S)-3-( tert-butoxy)-2-((2 S,3 R)-3-( tert-butoxy)-2-(( S)-2-((2 S,3 R)-3-( tert-butoxy)-2-(2-(( S)-5-( tert-butoxy)-2-(2-(( S)-3-(4-( tert-butoxy)phenyl)-2-(( tert-butoxycarbonyl)amino)propanamido)-2-methylpropanamido)-5-oxopentanamido)acetamido)butanamido)-3-phenylpropanamido)butanamido)propanamido)-4-oxobutanamido)-3-(4-( tert-butoxy)phenyl)propanamido)propanamido)-3-methylpentanamido)-2-methylpropanoyl)- L-leucine 955-183-8 - - View substance registered dossier
Bayer AG Kaiser-Wilhelm-Allee 51373 Leverkusen Germany Germany Active (2-(1-Chlorocyclopropyl)-3-(2-chlorophenyl)propyl)hydrazine 449-460-8 - 2011; 2023 View substance registered dossier
Esteve Quimica, S.A. Torre Esteve Passeig de la Zona Franca, 109, 4ª Planta 08038 Barcelona Barcelona Spain Spain Active (2-(1-isopropyl-1H-pyrazol-5-yl)pyrid-3-yl)methanol hydrochloride (1:1) 941-991-8 - - View substance registered dossier
Colors & Effects France S.A.S. Rue de la Chapelle 28 68330 Huningue France France Cease Manufacture (2-(2-hydroxyethoxy)ethyl) oxo(phenyl)acetate;reaction mass of: 2-(2-((oxo(phenyl)acetyl)oxy)ethoxy)ethyl oxo(phenyl)acetate 442-300-8 - 2015 View substance registered dossier
WSP UK Ltd. WSP HOUSE 70 CHANCERY LANE WC2A 1AF LONDON United Kingdom United Kingdom No longer Valid (2-(2-hydroxyethoxy)ethyl) oxo(phenyl)acetate;reaction mass of: 2-(2-((oxo(phenyl)acetyl)oxy)ethoxy)ethyl oxo(phenyl)acetate 442-300-8 - 2021 View substance registered dossier
IGM Resins Ltd c/o Baldwins, Wynyard Park House Wynyard Avenue TS22 5TB Wynyard Durham United Kingdom United Kingdom No longer Valid (2-(2-hydroxyethoxy)ethyl) oxo(phenyl)acetate;reaction mass of: 2-(2-((oxo(phenyl)acetyl)oxy)ethoxy)ethyl oxo(phenyl)acetate 442-300-8 - 2021 View substance registered dossier
IGM Resins Italia S.r.l Via Vincenzo Monti, 8 20123 Milano Italy Italy Active (2-(2-hydroxyethoxy)ethyl) oxo(phenyl)acetate;reaction mass of: 2-(2-((oxo(phenyl)acetyl)oxy)ethoxy)ethyl oxo(phenyl)acetate 442-300-8 - 2014; 2016; 2017 View substance registered dossier
Kao Chemicals GmbH Kupferstrasse 1 46446 Emmerich Northrhine-Westfalia Germany Germany Active (2-butoxyethoxy)acetic acid 451-650-0 - 2010 View substance registered dossier
Curia France SAS ZI de Laville 47240 BON-ENCONTRE France France Active (2-formamido-1,3-thiazol-4-yl)(oxo)acetic acid 426-680-2 - - View substance registered dossier
Corden Pharma Latina S.p.A. Via Murillo, 7 IT04013 Sermoneta (LT) Lazio Italy Italy Active (2-formamido-1,3-thiazol-4-yl)(oxo)acetic acid 426-680-2 - 2013 View substance registered dossier
Pfizer Ireland Pharmaceuticals n/a P43 X336 Ringaskiddy Cork Ireland Ireland Active (2E)-N-(5-Cyano-4-{(E)-[(dimethylamino)methylene]amino}-2-methoxyphenyl)-4-(piperidin-1-yl)but-2-enamide 939-152-6 - - View substance registered dossier
MINAKEM Beuvry Production SAS 145, Chemin des Lilas 59310 Beuvry-la-Forêt France France Active (2R)-2-(2,5-difluorophenyl)pyrrolidine, (2R,3R)-2,3-bis[(4-methoxybenzoyl)oxy]butanedioic acid 951-764-5 - - View substance registered dossier
Excella GmbH & Co. KG Nuernberger Str. 12 90537 Feucht Germany Germany Active (2R)-N-(2,6-Dimethylphenyl)-1-propylpiperidine-2-carboxamide - (2R,3R)-2,3-dihydroxysuccinic acid - propan-2-ol (2:1:1) 947-841-8 - - View substance registered dossier
Pfizer Ltd Ramsgate Road (IPC 979) CT13 9NJ Sandwich Kent United Kingdom United Kingdom No longer Valid (2R*,3S*)-2-(2,4-difluorophenyl)-3-(5-fluoro-4-pyrimidinyl)-1-(1H-1,2,4-triazol-1-yl)butan-2-ol (1R)-10-camphorsulfonate 427-100-0 - 2021 View substance registered dossier
Excella GmbH & Co. KG Nuernberger Str. 12 90537 Feucht Germany Germany Active (2R,3R)-2,3-Dihydroxybutanedioic acid-(2S)-N-(2,6-dimethylphenyl)-1-propylpiperidine-2-carboxamide (1/1) 947-840-2 - - View substance registered dossier
F.I.S. Fabbrica Italiana Sintetici S.p.a. Viale Milano, 26 36075 Montecchio Maggiore (VI) Veneto Italy Italy Active (2R,3R,11bR)-3-Isobutyl-9,10-dimethoxy-1,3,4,6,7,11b-hexahydro-2H-pyrido[2,1-a]isoquinolin-2-ol [(1S,4R)-7,7-Dimethyl-2-oxobicyclo[2.2.1]hept-1-yl]methanesulfonic acid 948-743-8 - - View substance registered dossier
[Confidential] - - - (2S)-2-[[(2S)-6-[[2-[2-[2-[[2-[2-[2-[[(4S)-5-tert-butoxy-4-[(20-tert-butoxy-20-oxo-icosanoyl)amino]-5-oxo-pentanoyl]amino]ethoxy]ethoxy]acetyl]amino]ethoxy]ethoxy]acetyl]amino]-2-[[(2S)-2-[[(2S)-2-[[(2S,3S)-2-[[(2S)-6-(tert-butoxycarbonylamino)-2-[[(2S)-4-tert-butoxy-2-(9H-fluoren-9-ylmethoxycarbonylamino)-4-oxo-butanoyl]amino]hexanoyl]amino]-3-methyl-pentanoyl]amino]propanoyl]amino]-5-oxo-5-(tritylamino)pentanoyl]amino]hexanoyl]amino]propanoic acid 954-943-6 - - View substance registered dossier
[Confidential] - - - (2S)-2-hydrazinyl-3-[4-hydroxy-3-(substituted)phenyl]-2-alkylpropanoic acid - - - View substance registered dossier
[Confidential] - - - (2S)-2-hydrazinyl-3-[4-hyrdoxy-3-(substituted)phenyl]-2-alkylpropanoic acid — tert-alkylamine (1/1) - - - View substance registered dossier

In this table, you will find all public data submitted to ECHA in REACH registration dossiers by substance manufacturers, importers, or their representatives, as laid out by the REACH Regulation (see Understanding REACH regulation).

ECHA makes available this information as REACH registered substance factsheets, which contain the full set of non-confidential information from related registration dossiers for a substance. Depending on the number of registrations that have been made for a substance, one factsheet can thus represent data from anything between hundreds of registration dossiers in a joint submission, to data from just one registration dossier.

As noted in the Legal Notice of the ECHA website, ECHA does not give any guarantees or warranties regarding the quality and correctness of the published information. The information in the portal is published ‘as provided’ by industry, and its accuracy has not been verified by ECHA. ECHA is also not in a position to intervene with, edit or correct the published data; this can only be done by the registrant responsible for its submission. Please also note that the information may be protected and its use may require prior permission from its owner (see the ECHA website Legal Notice more details).

In the portal results table are presented:

  • Public substance identity – the best available non-confidential substance name, EC, and CAS numbers.
  • Registration status – indicating the calculated registration status for the whole factsheet: Active – is being manufactured or imported to the EEA by one or more registrants; Cease Manufacture - is no longer being manufactured or imported above 1 tone per calendar year. All registrants of the substance have reported a cease of manufacture or import; or No longer valid - no longer considered registered under REACH and not currently allowed to be manufactured or imported to the EEA, until the substance is registered again.
  • Registration type – indicating whether a given factsheet contains data from a REACH full registration, REACH intermediate registration, or only a limited set of data inherited from a NONS notification.
  • Submission type – indicating whether the data in a given factsheet was submitted jointly or individually.
  • Total tonnage band – calculated per factsheet from all contributing registrations, based on the estimated quantity of the substance placed on the market. Data is excluded from dossiers where the tonnage is claimed confidential, from Intermediate registration dossiers, and from NONs which have not been updated.
  • Last updated – indicating the date on which this registered substance factsheet was last modified with new or updated data, based on an industry submission.
  • Link to the full factsheet.

A subset of the key chemical properties (physico-chemical, environmental fate, ecotoxicological and toxicological data) of registered substances can be searched and accessed via the OECD eChemPortal.

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