1-(2,2,4-trimethyl-3,4-dihydroquinolin-l (2H)-yl)ethanone

Guidance on Safe Use

First-aid measures

- General advice:

Move out of dangerous area. Place and transport victim in stable position (lying sideways). Remove contaminated clothing immediately and dispose of safely.

- Following inhalation:

Move to fresh air. Keep patient warm and at rest. Call a physician or poison control center immediately

- Following skin contact:

Wash off thoroughly with plenty of soap and water, if available with polyethyleneglycol 400, subsequently rinse with water. Call a physician or poison control center immediately.

- Following eye contact:

Rinse immediately with plenty of water, also under the eyelids, for at least 15 minutes. Remove contact lenses, if present, after the first 5 minutes, then continue rinsing eye. Call a physician or poison control center immediately.

- Following ingestion:

Rinse mouth. Do NOT induce vomiting. Call a physician or poison control center immediately.

- Most important symptoms and effects: No further relevant information available.

Fire-fighting measures

- Suitable extinguishing media:

Use fire fighting measures that suit the environment.

- Special hazards arising from the substance or mixture:

Dangerous gases are evolved in the event of a fire. In the event of fire the following may be released: Nitrogen oxides (NOx), Carbon monoxide (CO), Carbon dioxide (CO2)

- Advice for fire fighter: In the event of fire and/or explosion do not breathe fumes. Wear self-contained breathing apparatus and protective suit.

Accidental release measures

- Personal precautions, protective equipment and emergency procedures:

Avoid causing dust. Avoid contact with spilled product or contaminated surfaces. Use personal protective equipment.

- Environmental precautions:

Do not allow to enter drainage system, surface or ground water.

- Methods and material for containment and cleaning up: Avoid dust formation. Use mechanical handling equipment. Clean contaminated floors and objects thoroughly, observing environmental regulations. Collect and transfer the product into a properly labelled and tightly closed container.

Handling and storage

This substance is handled under Strictly Controlled Conditions in accordance with  REACH regulation Article 17(3) for on-site isolated intermediates and, in case the substance is transported to other sites for further processing, the substance should be handled at these sites under the Strictly Controlled Conditions as specified in REACH regulation Article 18(4).  Site documentation to support safe handling arrangements including the selection of engineering, administrative and personal protective equipment controls in accordance with risk-based management systems is available at each manufacturing site.

 

Written confirmation of application of Strictly Controlled Conditions has been received from every affected Distributor and Downstream Processor/User of the Registrant’s intermediate.

 

- Precautions for safe handling:

Avoid dust formation. Use only in area provided with appropriate exhaust ventilation. 

- Hygiene measures
Avoid contact with skin, eyes and clothing. Keep working clothes separately. Wash thoroughly with soap and water after handling. Remove soiled clothing immediately and clean thoroughly before using again. Garments that cannot be cleaned must be destroyed (burnt).

- Advice on protection against fire and explosion:

Use only in suitably equipped explosive areas using devices suitable for these areas. Dust may form explosive mixture in air. Keep away from heat and sources of ignition. Dust may form explosive mixture in air.

- Conditions for safe storage, including any incompatibilities: Store in original container. Keep containers tightly closed in a cool, well-ventilated place. Store in a place accessible by authorized persons only. Keep away from direct sunlight.

Transport information

Land transport (UN RTDG/ADR/RID)

UN number:

UN 3077

Shipping information

Proper shipping name and description:

ENVIRONMENTALLY HAZARDOUS SUBSTANCE, SOLID, N.O.S.

Chemical name:

1-ACETYL-2,2,4-TRIMETHYL-1,2,3,4-TETRAHYDROQUINOLINE

Language:

English

Class or division:

Class 9: Miscellaneous dangerous substances and articles, including environmentally hazardous substances

Packing group:

Packing group III: Substances presenting low danger

Labels:

Packaging/Bulk: 9 +EHS
Haz ID 90, EAC 2Z

SpecialProvisions

Inland waterway transport (UN RTDG/ADN(R))

UN number:

UN 3077

Shipping information

Proper shipping name and description:

ENVIRONMENTALLY HAZARDOUS SUBSTANCE, SOLID, N.O.S.

Chemical name:

1-ACETYL-2,2,4-TRIMETHYL-1,2,3,4-TETRAHYDROQUINOLINE

Language:

English

Class or division:

Class 9: Miscellaneous dangerous substances and articles, including environmentally hazardous substances

Packing group:

Packing group III: Substances presenting low danger

Labels:

Packaging/Bulk: 9 +EHS
Haz ID 90

Remarks

Marine transport (UN RTDG/IMDG)

UN number:

UN 3077

Shipping information

Proper shipping name and description:

ENVIRONMENTALLY HAZARDOUS SUBSTANCE, SOLID, N.O.S.

Chemical name:

1-ACETYL-2,2,4-TRIMETHYL-1,2,3,4-TETRAHYDROQUINOLINE

Language:

English

Class or division:

Class 9: Miscellaneous dangerous substances and articles, including environmentally hazardous substances

Packing group:

Packing group III: Substances presenting low danger

EmS code:

F-A

S-F

Labels:

9

Marine pollutant

Remarks

Air transport (UN RTDG/ICAO/IATA)

UN number:

UN 3077

Shipping information

Proper shipping name and description:

ENVIRONMENTALLY HAZARDOUS SUBSTANCE, SOLID, N.O.S.

Chemical name:

1-ACETYL-2,2,4-TRIMETHYL-1,2,3,4-TETRAHYDROQUINOLINE

Language:

English

Class or division:

Class 9: Miscellaneous dangerous substances and articles, including environmentally hazardous substances

Packing group:

Packing group III: Substances presenting low danger

Labels:

9 + EHS

Remarks

SpecialProvisions

Exposure controls / personal protection

This substance is handled under Strictly Controlled Conditions in accordance with REACH regulation Article 17(3) for on-site isolated intermediates and, in case the substance is transported to other sites for further processing, the substance should be handled at these sites under the Strictly Controlled Conditions as specified in REACH regulation Article 18(4). Site documentation to support safe handling arrangements including the selection of engineering, administrative and personal protective equipment controls in accordance with risk-based management systems is available at each manufacturing site.

 

Written confirmation of application of Strictly Controlled Conditions has been received from every affected Distributor and Downstream Processor/User of the Registrant’s intermediate.

 

 

- Respiratory protection:

Respiratory protection is not required under anticipated circumstances of exposure.
Respiratory protection should only be used to control residual risk of short duration activities, when all reasonably practicable steps have been taken to reduce exposure at source e.g. containment and/or local extract ventilation. Always follow respirator manufacturer's instructions regarding wearing and maintenance.

 

- Hand protection: 

Please observe the instructions regarding permeability and breakthrough time which are provided by the supplier of the gloves. Also take into consideration the specific local conditions under which the product is used, such as the danger of cuts, abrasion, and the contact time. Wash gloves when contaminated. Dispose of when contaminated inside, when perforated or when contamination on the outside cannot be removed. Wash hands frequently and always before eating, drinking, smoking or using the toilet.

Material: Nitrile rubber

Rate of permeability: > 480 min

Glove thickness: > 0,4 mm

Protective index: Class 6

Directive Protective gloves complying with EN 374.

 

- Eye protection:

Wear goggles (conforming to EN166, Field of Use = 5 or equivalent).

 

- Skin and body protection:

Wear standard coveralls and Category 3 Type 4 suit. If there is a risk of significant exposure, consider a higher protective type suit. Wear two layers of clothing wherever possible. Polyester/cotton or cotton overalls should be worn under chemical protection suit and should be professionally laundered frequently.

If chemical protection suit is splashed, sprayed or significantly contaminated, decontaminate as far as possible, then carefully remove and dispose of as advised by manufacturer

Stability and reactivity

- Reactivity: 

Thermal decomposition: Stable under normal conditions.

 

- Chemical stability: Stable under recommended storage conditions.

 

- Possibility of hazardous reactions: No hazardous reactions when stored and handled according to prescribed instructions.

 

- Conditions to avoid: Extremes of temperature and direct sunlight. Heat, flames and sparks.

 

- Incompatible materials: Store only in the original container.

 

- Hazardous decomposition products: No decomposition products expected under normal conditions of use.

Disposal considerations

During the whole life cycle of the substance all necessary measures in accordance to art. 18(4) of (EC) 1907/2006 are undertaken. The substance is handled under strictly controlled conditions.

Dispose in accordance with current regulations and, if necessary, after consultation with the site operator and/or with the responsible authority, the product may be taken to a waste disposal site or incineration plant.