Registration Dossier
Registration Dossier
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EC number: - | CAS number: -
Toxicity to microorganisms
Administrative data
Link to relevant study record(s)
Description of key information
EC 50 >> 655 mg/L (based on active ingredient)
EC 20 > 655 mg/L (based on active ingredient)
Key value for chemical safety assessment
- EC50 for microorganisms:
- 655 mg/L
- EC10 or NOEC for microorganisms:
- 655 mg/L
Additional information
A study is available on Reactive Orange 16, with a contact time of 30 minutes. At the highest tested concentration :100 mg / L , no significant inhibition was observed. Thus, the values of EC50 and EC20 are greater than 100 mg / L.
An examination of similar substance 3 , toxicity to bacteria ("bacterial toxicity") was made in the oxygen-inhibition test ("test Robra") plants with activated sludge from municipal wastewater biological treatment Frankfurt / M - Sindlingen as inoculum. The provision of the inhibition rate of oxygen consumption after 3 hours of exposure to the test item on bacteria test gave the following results:
Median inhibitory concentration, EC50: >> 1000 mg/L , NOEC, EC20 : >1000 mg/L (655 mg/L based on active ingresient) , EC 80: >> 1000 mg/L.
Similar substance 2 is very similar isomer of reactive orange 16 and therefore the microbial toxicity can be taken in read across supported also by the qualitative assessment on Reactive Orange 16 described in Chemosphere article and the result on similar substance 3.
All the assessments have consistent results.
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