Registration Dossier
Registration Dossier
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EC number: 935-411-2 | CAS number: -
Hydrolysis
Administrative data
Link to relevant study record(s)
Description of key information
A hydrolysis as a function of pH was conducted on the analogue substance 2 moles ethoxylated bisphenol A dimethacrylate, EC 939-702-5, in accordance with the OECD 111 test guideline and GLP principles.
The hydrolysis of the test item was assessed in aqueous buffers pH 4, 7 and 9 at 50 ± 0.5°C (Tier I). Tier II tests were conducted at pH 4, 7 and 9, for which a significant loss of test item had occurred, at 15, 37 and 50°C.
The half-life of the test item at pH 4.0 and 25°C was determined to be 39.6 days (i.e. 950.9 hours).
The half-life of the test item at pH 7.0 and 25°C was determined to be 12.7 days (i.e. 304.2 hours).
The half-life of the test item at pH 9.0 and 25°C was determined to be 8.1 days (i.e. 194.0 hours).
The results indicate that hydrolysis takes place at a slow rate under environmental conditions, with a half-life over several days. For the chemical safety assessment, a half-life of 12.7 days (pH 7 at 25°C) was selected as a representative value.
Key value for chemical safety assessment
- Half-life for hydrolysis:
- 12.7 d
- at the temperature of:
- 25 °C
Additional information
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