Registration Dossier
Registration Dossier
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EC number: 907-745-9 | CAS number: -
Carcinogenicity
Administrative data
Description of key information
Weight of evidence: Read-across approach from an analogue.
The analogue CAS No. 128-37-0 (BHT) which shares the same functional group (alkylphenol) with the two main constituents of the substance Reaction mass of 2,6-di-tert-butylphenol and 2,4,6-tri-tert-butylphenol, also has comparable values for the relevant molecular properties. Therefore, the results obtained with the substance CAS No. 128 -37-0 can be used for the read-across approach.
Based on experimental data, the read-across approach is applied and the substance is considered to be non-carcinogenic.
Key value for chemical safety assessment
Carcinogenicity: via oral route
Endpoint conclusion
- Endpoint conclusion:
- no adverse effect observed
- Quality of whole database:
- Weight of evidence: Read-across approach from an analogue.
Carcinogenicity: via inhalation route
Endpoint conclusion
- Endpoint conclusion:
- no study available
Carcinogenicity: via dermal route
Endpoint conclusion
- Endpoint conclusion:
- no study available
Justification for classification or non-classification
Based on the available data, the substance is not classified as carcinogenic.
Additional information
Weight of evidence: Read-across approach from an analogue.
The analogue CAS No. 128-37-0 (BHT) which shares the same functional group (alkylphenol) with the two main constituents of the substance Reaction mass of 2,6-di-tert-butylphenol and 2,4,6-tri-tert-butylphenol, also has comparable values for the relevant molecular properties. Therefore, the results obtained with the substance CAS No. 128 -37-0 can be used for the read-across approach.
Based on experimental data, the read-across approach is applied and the substance is considered to be non-carcinogenic.
Justification for selection of carcinogenicity via oral route endpoint:
Weight of evidence: Read-across approach from an analogue.
The analogue CAS No. 128-37-0 (BHT) which shares the same functional group (alkylphenol) with the two main constituents of the substance Reaction mass of 2,6-di-tert-butylphenol and 2,4,6-tri-tert-butylphenol, also has comparable values for the relevant molecular properties. Therefore, the results obtained with the substance CAS No. 128 -37-0 can be used for the read-across approach.
Based on experimental data, the read-across approach is applied and the substance is considered to be non-carcinogenic.
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