Registration Dossier
Registration Dossier
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EC number: 905-728-0 | CAS number: -
Endpoint summary
Administrative data
Link to relevant study record(s)
Description of key information
The absorption efficiencies used in the assessment are:
Dermal - 10%
Oral - 100%
Inhalation - 100%
Key value for chemical safety assessment
- Bioaccumulation potential:
- low bioaccumulation potential
- Absorption rate - oral (%):
- 100
- Absorption rate - dermal (%):
- 10
- Absorption rate - inhalation (%):
- 100
Additional information
There are no specific toxicokinetic studies of 2 -EHDPP, but toxicology testing appears to indicate that it is readily absorbed via the oral route. Due to its rapid hydrolysis in water, it may be appropriate to consider the toxicokinetics of phenol for oral and inhalation routes since there would be a high likelihood of hydrolysis via these routes. The Phenol RAR (ECB 2006) concludes 100% absorption via the oral and inhalation routes and rapid elimination with low potential for bioaccumulation. These conclusions are also being applied to 2 -EHDPP.
The basis for the dermal absorption recommendation is discussed in Section 7.1.2.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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