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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Physical & Chemical properties

Dissociation constant

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Administrative data

Link to relevant study record(s)

Reference
Endpoint:
dissociation constant
Type of information:
other: Expert assessment
Adequacy of study:
key study
Study period:
2010
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: Assessment based on properties of the substance and chemical structure.
Qualifier:
no guideline followed
Principles of method if other than guideline:
Assessment based on properties of the substance and chemical structure.
GLP compliance:
no
Dissociating properties:
no
Conclusions:
The substance is not expected to dissociate under normal conditions.
Executive summary:

The dissociation constant of the registered substance was estimated via an assessment of the properties and chemical structure of the substance. Although this study is technically possible to perform (although being surface active, multi-constituent and poorly water soluble, any testing would be very difficult), structural assessment suggests that there will be no dissociation under normal environmental or biological conditions. Under extreme acid or basic conditions, the OH group at the end of each propylene oxide group could in theory dissociate, but the conditions would need to be more extreme than found under normal biological conditions. The substance is not considered to dissociate under normal conditions.

Description of key information

Although this study is technically possible to perform (although being surface active, multi-constituent and poorly water soluble, any testing would be very difficult), structural assessment suggests that there will be no dissociation under normal environmental or biological conditions. Under extreme acid or basic conditions, the OH group at the end of each propylene oxide group could in theory dissociate, but the conditions would need to be more extreme than found under normal biological conditions. The substance is not considered to dissociate under normal conditions. This waiver is supported by the following information gathered from an assessment of the properties of the substance and the chemical structure.

Key value for chemical safety assessment

Additional information

The dissociation constant of the registered substance was estimated via an assessment of the properties and chemical structure of the substance. Although this study is technically possible to perform (although being surface active, multi-constituent and poorly water soluble, any testing would be very difficult), structural assessment suggests that there will be no dissociation under normal environmental or biological conditions. Under extreme acid or basic conditions, the OH group at the end of each propylene oxide group could in theory dissociate, but the conditions would need to be more extreme than found under normal biological conditions. The substance is not considered to dissociate under normal conditions.