Registration Dossier
Registration Dossier
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EC number: 310-051-3 | CAS number: 102110-50-9 The residues obtained by the addition of aluminum or zinc to end liquors obtained from secondary refining of gold, iridium, osmium, palladium, platinum, rhenium, ruthenium or silver. Composed primarily of the precious metals, ammonium chloride and chlorides of aluminum, magnesium and zinc.
Endpoint summary
Administrative data
Key value for chemical safety assessment
Additional information
Substance specific information for the UVCB substance "Residues, precious metal refining cementation" is not available for the endpoint "Genetic Toxicity". In order to meet the requirements for Annex VII till Annex X of Regulation (EC) 1907/2006, read across information from any constituents being relevant needs to be included. Due to the high number of constituents and variability in C&L it was agreed within the consortium to use the classification information from the individual constituents and calculate the resulting classification by using the “generic concentration limits of ingredients of a mixture classified as germ cell mutagens that trigger classification of the mixture.” and respective rules of Regulation (EC) 1272/2006 section 3.5.3.1. “Classification of mixtures when data are available for all ingredients or only for some ingredients of the mixture” with the MeClas tool.
In total two different grades of "Residues, precious metal refining cementation" (Residues 1 and Residues 2) were identified by the consortium that could be grouped according to their calculated C&L resulting from the individual composition. Thus, for "Residues, precious metal refining cementation" two C&L entries (no C&L (Residues 1) and Muta. 2 (Residues 2)) for genetic toxicity were calculated.
Short description of key information:
No information on animal testing of "Residues, precious metal refining cementation" is available. "Residues, precious metal refining cementation" (Residues 2) contains no constituent ≥ 0.1 % classified as mutagen Muta. 1, but one constituent ≥ 1 % classified as mutagen Muta. 2 (NiSO4). Thus, the substance should be classified as germ cell mutagen Muta. 2 (H341).
Endpoint Conclusion: Adverse effect observed (positive)
Justification for classification or non-classification
"Residues, precious metal refining cementation" (Residues 2) contains no constituent ≥ 0.1 % classified as mutagen Muta. 1, but one constituent ≥ 1 % classified as mutagen Muta. 2 (NiSO4). Thus, the substance should be classified as germ cell mutagen Muta. 2 (H341) in accordance with Regulation (EC) 1272/2008.
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