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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Physical & Chemical properties

Flammability

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Administrative data

Endpoint:
flammable solids
Type of information:
experimental study
Adequacy of study:
key study
Study period:
27 February 2020
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2020
Report date:
2020

Materials and methods

Test guidelineopen allclose all
Qualifier:
according to guideline
Guideline:
UN Manual of Tests and Criteria: Test N.1 (Test method for readily combustible solids)
Deviations:
no
Qualifier:
according to guideline
Guideline:
EU Method A.10 (Flammability (Solids))
Deviations:
no
GLP compliance:
yes (incl. QA statement)

Test material

Constituent 1
Chemical structure
Reference substance name:
(R*,R*)-1,4-dimercaptobutane-2,3-diol
EC Number:
222-468-7
EC Name:
(R*,R*)-1,4-dimercaptobutane-2,3-diol
Cas Number:
3483-12-3
Molecular formula:
C4H10O2S2
IUPAC Name:
1,4-disulfanylbutane-2,3-diol
Specific details on test material used for the study:
Batch No.: 44606300 / 50774
Storage Conditions: 2°C to 8°C, under nitrogen

Results and discussion

Flammable solids
Key result
Test procedure:
burning rate test: preliminary screening test
Remarks on result:
substance does not ignite and propagate combustion either by burning with flame or smouldering along 200 mm of the powder train within the 2 minutes test period

Any other information on results incl. tables

The test item1,4-Dithiothreitol (CAS no.3483-12-3) did not ignite at room temperature using a flame as ignition source being applied for at least 2 minutes. The test item melted. Thus, the performance of the main test was not necessary.

Applicant's summary and conclusion

Interpretation of results:
not classified based on GHS criteria
Conclusions:
The test item 1,4 Dithiothreitol (CAS no. 3483-12-3) could not be ignited applying a flame as ignition source for at least 2 minutes. Therefore, the product should not be classified as readily combustible solid in class 4, Division 4.1 according to the UN Transport Regualtion or as flammable solid according to the GHS/CLP Regulation EC 1272/2008 Annex 1: 2.7.
Executive summary:

The test item 1,4 Dithiothreitol (CAS no. 3483-12-3) could not be ignited applying a flame as ignition source for at least 2 minutes. Therefore, the product should not be classified as readily combustible solid in class 4, Division 4.1 according to the UN Transport Regualtion or as flammable solid according to the GHS/CLP Regulation EC 1272/2008 Annex 1: 2.7.