Tributyltin chloride

Melting point / freezing point

Link to relevant study record(s)

Reference

Endpoint:

melting point/freezing point

Type of information:

experimental study

Adequacy of study:

key study

Study period:

22 April 2010 to 02 June 2010

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

guideline study

Qualifier:

according to guideline

Guideline:

EU Method A.1 (Melting / Freezing Temperature)

Version / remarks:

Using BS4633: Method for the Determination of Crystallizing Point, designed to be compatible with Method A.1

Deviations:

no

GLP compliance:

yes (incl. QA statement)

Remarks:

in compliance with UK GLP standards (Schedule 1, Good Laboratory Practice Regulations 1999 (SI 1999/3106 as amended by SI 2004/0994))

Type of method:

method to determine freezing temperature

Key result

Melting / freezing pt.:

< 253 K

Remarks on result:

other: ± 0.5 K

Key result

Melting / freezing pt.:

< -20 °C

Remarks on result:

other: ± 0.5 °c

Table 1: Cooling Data from Determination 1

Time(s)	Temperature (K)	Time(s)	Temperature (K)	Time(s)	Temperature (K)
0	291.55	690	264.55	1380	257.55
30	290.75	720	263.75	1410	257.55
60	289.15	750	263.15	1440	257.35
90	287.35	780	262.15	1470	257.35
120	286.15	810	261.35	1500	257.15
150	284.15	840	261.15	1530	256.95
180	283.15	870	260.75	1560	256.95
210	281.55	900	260.35	1590	256.95
240	280.15	930	259.95	1620	256.55
270	279.15	960	259.55	1650	256.15
300	178.15	990	259.15	1680	255.95
330	276.15	1020	258.95	1710	255.75
360	275.75	1050	258.55	1740	255.35
390	274.55	1080	258.35	1770	255.35
420	273.75	1110	258.15	1800	255.55
450	272.55	1140	258.35	1830	255.95
480	271.35	1170	258.35	1860	256.15
510	270.15	1200	258.35	1890	256.15
540	269.15	1230	258.15	1920	256.15
570	268.15	1260	257.95	1950	256.15
600	267.15	1290	257.75	1980	256.15
630	266.15	1320	257.75	2700*	252.15
660	265.35	1350	257.75
*No readings were performed between 1980 and 2700 seconds due to the technician and Study Director discussing the test procedure.

Observations: The test material did not change in appearance throughout the test.
Result: Freezing temperature <253 K (<-20.0 °C)

Table 2: Cooling Data from Determination 2

Time(s)	Temperature (K)	Time(s)	Temperature (K)	Time(s)	Temperature (K)
0	288.75	690	263.35	1380	256.75
30	287.75	720	262.55	1410	256.15
60	286.95	750	262.15	1440	255.75
90	284.75	780	261.95	1470	255.35
120	283.15	810	261.35	1500	255.15
150	281.35	840	260.95	1530	254.95
180	280.15	870	260.35	1560	254.75
210	279.15	900	259.95	1590	254.35
240	277.95	930	259.75	1620	254.15
270	276.55	960	259.15	1650	253.75
300	275.55	990	258.95	1680	253.35
330	274.15	1020	258.55	1710	253.35
360	272.75	1050	258.15	1740	253.35
390	271.55	1080	257.95	1770	253.15
420	270.35	1110	257.55	1800	252.95
450	269.15	1140	257.35	1830	252.55
480	268.35	1170	257.55	1860	252.35
510	267.35	1200	257.75	1890	252.35
540	266.35	1230	257.75	1920	252.15
570	265.95	1260	257.75
600	265.35	1290	257.55
630	264.55	1320	257.55
660	263.95	1350	257.15

Observations: The test material did not change in appearance throughout the test.
Result: Freezing temperature <253 K (<-20.0 °C)

Conclusions:

The freezing temperature of the the test material has been determined to be less than 253 ± 0.5 K (less than -20.0 ± 0.5 °C).

Executive summary:

In a GLP study conducted to a BS4633: Method for the Determination of Crystallizing Point, designed to be compatible with EU Method A.1, the freezing point of the test material was determined.

Under the conditions of this study, the freezing point of the test material was recorded to be less than 253 K (± 0.5 K), less than 20 °C (± 0.5 °C).

Description of key information

In a GLP study conducted to a BS4633: Method for the Determination of Crystallizing Point, designed to be compatible with EU Method A.1, the freezing point of the test material was determined. The freezing point of the test material was recorded to be less than 253 K (± 0.5 K), less than -20 °C (± 0.5 °C).

Key value for chemical safety assessment

Melting / freezing point at 101 325 Pa:

-20 °C

Additional information

Butler RE & White DF (2010) was selected as the key study for this data requirementas the study was performed to a method designed to be compatible with EU method A.1, and was GLP compliant. The study was considered of high reliability and therefore suitable as a stand alone study. A reliability rating of 1 was assigned to this study, according to the criteria of Klimisch, 1997

Supporting information is also available from a material safety data sheet, Atofina Chemicals Inc. (2001).

A reliability rating of 4 was assigned to this study, according to the criteria of Klimisch, 1997 as this information is from a secondary source.

Result: - 18 °C (no pressure reported)