Registration Dossier
Registration Dossier
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EC number: 207-959-6 | CAS number: 503-01-5
Guidance on Safe Use
Administrative data
First-aid measures
4.1 Description of first aid measures
General information: First aider: Pay attention to self-protection!
Inhalation: Remove to fresh air. Get medical aid.
Skin contact: Wash off with plenty of water and soap for at least 15 minutes. Remove contaminated clothing and shoes. If irritation occurs or persists, get medical attention. Wash clothing and shoes before reuse.
In case of eye contact: After contact with the eyes, rinse with water with the eyelids open for a sufficient length of time, then consult an ophthalmologist immediately.
In case of ingestion: Wash mouth out with water. Call a physician immediately.
4.2 Most important symptoms and effects, both acute and delayed
Isomethepten is the API in different dosage form. The therapeutic category is: adrenergic, bronchodilator, mydriatic, antiglaucoma.
4.3 Indication of immediate medical attention and special treatment needed
When symptoms suggesting toxicity, immediate medical treatment necessary. If possible, show this data sheet.
Fire-fighting measures
5.1 Extinguishing media
Water spray, carbon dioxide, dry chemical powder, foam.
5.2 Special hazards arising from the substance or mixture
In case of fire may be liberated: Carbon monoxide, nitrogen oxides
5.3 Precautions for fire-fighters
Do not inhale explosion and combustion gases.
5.4 Further information
Contaminated fire extinguishing water must collect separately. It must not be discharged into drains.
Accidental release measures
6.1 Personal precautions, protective equipment and emergency procedures
Wear personal protection equipment. Wear breathing apparatus if exposed to vapours/dusts.
6.2 Environmental precautions
Do not allow to enter drains/surface water/ground-water.
6.3 Methods and materials for containment and cleaning up
Adsorb with chemical adsorbent material and dispose as waste requiring special attention.
Handling and storage
7.1 Precautions for safe handling
All work processes must always be designed so that the following is as low as possible: Inhalation, Skin contact, Eye contact. The substance is combustible.
The substance is registered under the Regulation EG1907/2006 (REACH) as a transported isolated intermediate; the use must be complied with the conditions in Article 18 (4).
7.2 Conditions for safe storage, including any incompatibilities
Provide adequate ventilation as well as local exhaustion at critical locations.
Keep container tightly closed and in a well-ventilated place. Do not store at temperatures above 30 °C.
7.3 Specific end uses
not applicable
Transport information
Land transport (UN RTDG/ADR/RID)
- UN number:
- 1993
Shipping information
- Proper shipping name and description:
- FLAMMABLE LIQUID, N.O.S.
- Chemical name:
- Isometheptene
- Language:
- English
- Labels:
- 3
SpecialProvisionsopen allclose all
Inland waterway transport (UN RTDG/ADN(R))
- UN number:
- 1993
Shipping information
- Proper shipping name and description:
- FLAMMABLE LIQUID, N.O.S.
- Chemical name:
- Isometheptene
- Language:
- English
- Labels:
- 3
Remarksopen allclose all
Marine transport (UN RTDG/IMDG)
- UN number:
- 1993
Shipping information
- Proper shipping name and description:
- FLAMMABLE LIQUID, N.O.S.
- Chemical name:
- Isomethepten
- Labels:
- 3
Remarksopen allclose all
Air transport (UN RTDG/ICAO/IATA)
- UN number:
- 1993
Shipping information
- Proper shipping name and description:
- FLAMMABLE LIQUID, N.O.S.
- Chemical name:
- Isomethepten
- Labels:
- 3
Remarksopen allclose all
SpecialProvisionsopen allclose all
Exposure controls / personal protection
8.1 Control parameters
Limits for occupational safety are not be valid, because the substance must be used in closed system according to Article 18 (4) REACH. Exposures are therefore minimized.
8.2 Exposure controls
Appropriate engineering controls:
Immediately change contaminated clothing. Wash thoroughly after handling. General room ventilation is adequate unless the process generates dust or fumes. Work clothing should be removed in a change room on site and laundered professionally. Employees should shower and change into street clothes before leaving the facility. Prevent the accumulation of dust in the work area by thorough periodic cleaning of the area.
Personal protective equipment:
Protective clothing should be selected specifically for the working place, depending on concentration and quantity of the hazardous substances handled. The resistance of the protective clothing to chemicals should be ascertained with the respective supplier.
Respiratory protection: Is required whenever air contamination (dust, mist, or vapors) is generated by the process. A NIOSH-approved high efficiency toxic dust/mist/fume respirator is recommended.
Eye protection: required
Hand protection: In full and splash contact:
Glove material: Butyl-/Nitrile rubber
Layer thickness: 0.11 mm
The protective gloves to be used must comply with the specifications of EC directive 89/686/EEC and the resultant standard EN374.
This recommendation applies only to the product stated in the safe data sheet and supplied by us as well as to the purpose specified by us. When dissolving in or mixing with other substances and under conditions deviating from those stated in EN374 please contact the supplier of CE-approved gloves.
Stability and reactivity
10.1 Reactivity
no special conditions
10.2 Chemical stability
Stable under normal conditions
10.3 Possibility of hazardous reactions
Oxidizing agents
10.4 Conditions to avoid
Light and elevated temperature
10.5 Incompatible materials
strong alkali, acids
Disposal considerations
Waste treatment methods
Product:
Product waste and residues must be disposed of according to current laws.
Packaging:
Non-contaminated packages may be recycled. Handle contaminated packaging in the same way as the substance itself.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
