Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 202-830-0 | CAS number: 100-21-0
Toxicity to microorganisms
Administrative data
Link to relevant study record(s)
Description of key information
In a reliable (Klimisch 1, guideline- and GLP-compliant) study of the toxicity of terephthalic acid to aquatic microorganisms (Lebertz, 1991), the 3 -h EC50, based on inhibition of respiration of activated sludge, was 1392.8 mg/L. Inhibition, relative to the untreated control, was observed at concentrations >/= 1000 mg/L and the NOEC was 500 mg/L. All the nominal concentrations applied exceeded the water-solubility of the test substance (dosed as the free acid), although it is likely that some more highly soluble terephthalate salts were formed by interaction between the acid and the mineral constituents of the synthetic sewage present in the test system. No pH measurements were reported; consequently it is uncertain to what degree a lowering of pH may have caused or contributed to the observed effect.
Key value for chemical safety assessment
- EC50 for microorganisms:
- 1 392.8 mg/L
- EC10 or NOEC for microorganisms:
- 500 mg/L
Additional information
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
